Published in J Mol Biol on December 27, 2005
A quantitative estimation of the global translational activity in logarithmically growing yeast cells. BMC Syst Biol (2008) 1.32
The 3' cap-independent translation element of Barley yellow dwarf virus binds eIF4F via the eIF4G subunit to initiate translation. RNA (2007) 1.22
Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands. EMBO J (2006) 1.21
The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond. Plant Physiol (2007) 1.10
eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition. Proc Natl Acad Sci U S A (2013) 1.09
Reduction in structural disorder and functional complexity in the thermal adaptation of prokaryotes. PLoS One (2010) 1.02
Binding specificities and potential roles of isoforms of eukaryotic initiation factor 4E in Leishmania. Eukaryot Cell (2006) 1.01
Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap. J Biol Chem (2009) 0.98
Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP. Eur J Med Chem (2009) 0.94
Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression. RNA (2012) 0.94
Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex. J Biol Chem (2008) 0.92
Structural insights into the allosteric effects of 4EBP1 on the eukaryotic translation initiation factor eIF4E. J Mol Biol (2011) 0.90
The eukaryotic translation initiation factor eIF4E in the nucleus: taking the road less traveled. Immunol Rev (2015) 0.84
Structural insights into parasite eIF4E binding specificity for m7G and m2,2,7G mRNA caps. J Biol Chem (2009) 0.83
Dynamic recognition of the mRNA cap by Saccharomyces cerevisiae eIF4E. Structure (2013) 0.83
eIF4E-binding protein regulation of mRNAs with differential 5'-UTR secondary structure: a polyelectrostatic model for a component of protein-mRNA interactions. Nucleic Acids Res (2012) 0.78
Minimum-noise production of translation factor eIF4G maps to a mechanistically determined optimal rate control window for protein synthesis. Nucleic Acids Res (2016) 0.75
Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol (2008) 9.24
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix. Science (2004) 7.63
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat Genet (2011) 6.89
Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science (2010) 5.44
Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A. Nat Chem Biol (2006) 3.89
Regulation of fungal gene expression via short open reading frames in the mRNA 5'untranslated region. Mol Microbiol (2003) 3.61
Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell (2003) 3.46
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science (2008) 3.38
The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell (2003) 3.36
The structural basis of yeast prion strain variants. Nature (2007) 3.31
Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha. Proc Natl Acad Sci U S A (2002) 3.28
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature (2006) 3.23
Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G. Cell (2007) 3.21
HIV-1 broadly neutralizing antibody extracts its epitope from a kinked gp41 ectodomain region on the viral membrane. Immunity (2008) 3.01
A nuclear receptor-like pathway regulating multidrug resistance in fungi. Nature (2008) 3.00
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival. Cell (2011) 2.98
Position of eukaryotic initiation factor eIF1 on the 40S ribosomal subunit determined by directed hydroxyl radical probing. Genes Dev (2003) 2.77
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection. Nature (2011) 2.71
Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation. Cell (2009) 2.60
The rhesus rotavirus VP4 sialic acid binding domain has a galectin fold with a novel carbohydrate binding site. EMBO J (2002) 2.41
The alphabeta T cell receptor is an anisotropic mechanosensor. J Biol Chem (2009) 2.41
Ultrahigh-resolution (1)H-(13)C HSQC spectra of metabolite mixtures using nonlinear sampling and forward maximum entropy reconstruction. J Am Chem Soc (2007) 2.40
Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase. Nature (2008) 2.39
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression. Nat Struct Mol Biol (2004) 2.37
Translation initiation: structures, mechanisms and evolution. Q Rev Biophys (2005) 2.31
Accelerated acquisition of high resolution triple-resonance spectra using non-uniform sampling and maximum entropy reconstruction. J Magn Reson (2004) 2.30
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a. Biochemistry (2002) 2.29
In situ observation of protein phosphorylation by high-resolution NMR spectroscopy. Nat Struct Mol Biol (2008) 2.23
Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2. Nat Struct Biol (2003) 2.23
A general framework for development and data analysis of competitive high-throughput screens for small-molecule inhibitors of protein-protein interactions by fluorescence polarization. Biochemistry (2004) 2.20
Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75. Nat Struct Mol Biol (2005) 2.17
Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways. Mol Cell Biol (2005) 2.13
Dynamics and processivity of 40S ribosome scanning on mRNA in yeast. Mol Microbiol (2004) 2.12
Mammalian SCAN domain dimer is a domain-swapped homolog of the HIV capsid C-terminal domain. Mol Cell (2005) 2.07
Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. J Am Chem Soc (2013) 1.90
Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites. Structure (2005) 1.86
Structural basis for the enhancement of eIF4A helicase activity by eIF4G. Genes Dev (2005) 1.83
Application of iterative soft thresholding for fast reconstruction of NMR data non-uniformly sampled with multidimensional Poisson Gap scheduling. J Biomol NMR (2012) 1.81
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface. Proc Natl Acad Sci U S A (2009) 1.79
Poisson-gap sampling and forward maximum entropy reconstruction for enhancing the resolution and sensitivity of protein NMR data. J Am Chem Soc (2010) 1.78
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL. Biochemistry (2007) 1.76
Modulation of eukaryotic mRNA stability via the cap-binding translation complex eIF4F. J Mol Biol (2002) 1.75
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts. J Biol Chem (2007) 1.72
RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation. Chem Biol (2006) 1.71
Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function. Mol Microbiol (2002) 1.71
Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact oocytes. Proc Natl Acad Sci U S A (2006) 1.70
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature (2008) 1.66
Domain-swapped dimerization of the HIV-1 capsid C-terminal domain. Proc Natl Acad Sci U S A (2007) 1.66
An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model. J Mol Biol (2009) 1.62
Modular architecture of the bacteriophage T7 primase couples RNA primer synthesis to DNA synthesis. Mol Cell (2003) 1.61
Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. Proc Natl Acad Sci U S A (2010) 1.61
Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing. Nucleic Acids Res (2009) 1.61
Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein. J Biol Chem (2002) 1.61
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. J Am Chem Soc (2009) 1.55
The kinetochore-bound Ska1 complex tracks depolymerizing microtubules and binds to curved protofilaments. Dev Cell (2012) 1.54
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proc Natl Acad Sci U S A (2008) 1.52
FM reconstruction of non-uniformly sampled protein NMR data at higher dimensions and optimization by distillation. J Biomol NMR (2009) 1.52
mRNA decapping is promoted by an RNA-binding channel in Dcp2. Mol Cell (2008) 1.50
Selective pharmacological targeting of a DEAD box RNA helicase. PLoS One (2008) 1.49
Solution structure of human initiation factor eIF2alpha reveals homology to the elongation factor eEF1B. Structure (2004) 1.48
Tetracycline-aptamer-mediated translational regulation in yeast. Mol Microbiol (2003) 1.46
The yeast eukaryotic initiation factor 4G (eIF4G) HEAT domain interacts with eIF1 and eIF5 and is involved in stringent AUG selection. Mol Cell Biol (2003) 1.46
Non-uniformly sampled double-TROSY hNcaNH experiments for NMR sequential assignments of large proteins. J Am Chem Soc (2006) 1.45
Mapping the binding interface between human eukaryotic initiation factors 1A and 5B: a new interaction between old partners. Proc Natl Acad Sci U S A (2003) 1.41
Reengineering orthogonally selective riboswitches. Proc Natl Acad Sci U S A (2010) 1.41
Is routine hysteroscopy during LLETZ a valuable additional procedure? Acta Obstet Gynecol Scand (2011) 1.39
Solution NMR structure determination of proteins revisited. J Biomol NMR (2008) 1.39
Alternate 13C-12C labeling for complete mainchain resonance assignments using C alpha direct-detection with applicability toward fast relaxing protein systems. J Am Chem Soc (2008) 1.39
Applications of non-uniform sampling and processing. Top Curr Chem (2012) 1.37
Selective inhibition of calcineurin-NFAT signaling by blocking protein-protein interaction with small organic molecules. Proc Natl Acad Sci U S A (2004) 1.37
Eukaryotic initiation factor (eIF) 1 carries two distinct eIF5-binding faces important for multifactor assembly and AUG selection. J Biol Chem (2007) 1.34
The eukaryotic initiation factor (eIF) 5 HEAT domain mediates multifactor assembly and scanning with distinct interfaces to eIF1, eIF2, eIF3, and eIF4G. Proc Natl Acad Sci U S A (2005) 1.34
Solution structure of the CD3epsilondelta ectodomain and comparison with CD3epsilongamma as a basis for modeling T cell receptor topology and signaling. Proc Natl Acad Sci U S A (2004) 1.33
Reinitiation and recycling are distinct processes occurring downstream of translation termination in yeast. J Mol Biol (2004) 1.32
Coupled decomposition of four-dimensional NOESY spectra. J Am Chem Soc (2009) 1.31
The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals. Nat Struct Mol Biol (2013) 1.31
Position of eukaryotic initiation factor eIF5B on the 80S ribosome mapped by directed hydroxyl radical probing. EMBO J (2007) 1.31
A PHD finger motif in the C terminus of RAG2 modulates recombination activity. J Biol Chem (2005) 1.31
Antibody mechanics on a membrane-bound HIV segment essential for GP41-targeted viral neutralization. Nat Struct Mol Biol (2011) 1.29
Exploring signal-to-noise ratio and sensitivity in non-uniformly sampled multi-dimensional NMR spectra. J Biomol NMR (2012) 1.29
eIF4G and CBP80 share a common origin and similar domain organization: implications for the structure and function of eIF4G. Biochemistry (2005) 1.26
Nonmicellar systems for solution NMR spectroscopy of membrane proteins. Curr Opin Struct Biol (2010) 1.24
IBIS--a tool for automated sequential assignment of protein spectra from triple resonance experiments. J Biomol NMR (2003) 1.24
Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA. EMBO J (2007) 1.23
CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. Mol Cell (2013) 1.23
Using codon optimization, chaperone co-expression, and rational mutagenesis for production and NMR assignments of human eIF2 alpha. J Biomol NMR (2004) 1.23
Fast assignment of 15N-HSQC peaks using high-resolution 3D HNcocaNH experiments with non-uniform sampling. J Biomol NMR (2005) 1.22
Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation. Proc Natl Acad Sci U S A (2011) 1.22
Translation initiation: variations in the mechanism can be anticipated. Cell Mol Life Sci (2010) 1.22
Molecular framework for the activation of RNA-dependent protein kinase. J Biol Chem (2007) 1.21
A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8. Science (2003) 1.21
Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p. J Biol Chem (2008) 1.20
Cell-free expressed bacteriorhodopsin in different soluble membrane mimetics: biophysical properties and NMR accessibility. Structure (2013) 1.19
NMR methods for studying protein-protein interactions involved in translation initiation. Methods Enzymol (2007) 1.19
Tumor suppression by small molecule inhibitors of translation initiation. Oncotarget (2012) 1.17
Unwinding single RNA molecules using helicases involved in eukaryotic translation initiation. J Mol Biol (2006) 1.17