Rocks: multifunctional kinases in cell behaviour.

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat Biotechnol (2011) 4.06

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells. J Cell Biol (2007) 4.03

Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection. Arterioscler Thromb Vasc Biol (2004) 3.18

Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J Cell Biol (2004) 3.03

Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A (2010) 3.01

Apical constriction: a cell shape change that can drive morphogenesis. Dev Biol (2009) 2.90

Physiological role of ROCKs in the cardiovascular system. Am J Physiol Cell Physiol (2006) 2.61

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol (2011) 2.59

mTORC2 regulates neutrophil chemotaxis in a cAMP- and RhoA-dependent fashion. Dev Cell (2010) 2.56

ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol (2005) 2.50

Applications for ROCK kinase inhibition. Curr Opin Cell Biol (2008) 2.28

GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA. Mol Biol Cell (2008) 2.24

Human keratinocytes are efficiently immortalized by a Rho kinase inhibitor. J Clin Invest (2010) 2.19

The Rho kinases I and II regulate different aspects of myosin II activity. J Cell Biol (2005) 2.16

ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton. Mol Biol Cell (2009) 2.10

Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice. Circulation (2005) 2.09

Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb Perspect Biol (2013) 2.00

Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation. Dev Cell (2010) 1.99

Rho GTPases: functions and association with cancer. Clin Exp Metastasis (2007) 1.98

ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury. J Clin Invest (2008) 1.92

Rho kinase (ROCK) inhibitors. J Cardiovasc Pharmacol (2007) 1.89

Big roles for small GTPases in the control of directed cell movement. Biochem J (2007) 1.89

Keeping in touch with contact inhibition of locomotion. Trends Cell Biol (2010) 1.85

Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma. Int J Cancer (2010) 1.81

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest (2013) 1.81

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol (2010) 1.79

Positive feedback between Dia1, LARG, and RhoA regulates cell morphology and invasion. Genes Dev (2007) 1.77

Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis. Proc Natl Acad Sci U S A (2006) 1.76

Rho signaling regulates pannexin 1-mediated ATP release from airway epithelia. J Biol Chem (2011) 1.76

An expression screen reveals modulators of class II histone deacetylase phosphorylation. Proc Natl Acad Sci U S A (2005) 1.71

Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab (2012) 1.66

Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy. EMBO Rep (2012) 1.66

Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins. Proc Natl Acad Sci U S A (2006) 1.64

Cyclooxygenase-2-derived prostaglandin E₂ promotes injury-induced vascular neointimal hyperplasia through the E-prostanoid 3 receptor. Circ Res (2013) 1.61

Rho kinase in the regulation of cell death and survival. Arch Immunol Ther Exp (Warsz) (2007) 1.60

Dynamics of the Rho-family small GTPases in actin regulation and motility. Cell Adh Migr (2011) 1.60

The Rho GTPase effector ROCK regulates cyclin A, cyclin D1, and p27Kip1 levels by distinct mechanisms. Mol Cell Biol (2006) 1.59

RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J (2005) 1.59

Regulation of V-ATPase recycling via a RhoA- and ROCKII-dependent pathway in epididymal clear cells. Am J Physiol Cell Physiol (2011) 1.57

Forcing stem cells to behave: a biophysical perspective of the cellular microenvironment. Annu Rev Biophys (2012) 1.55

Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis. Mol Biol Cell (2011) 1.54

Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices. Mol Biol Cell (2008) 1.54

Substrate stiffening promotes endothelial monolayer disruption through enhanced physical forces. Am J Physiol Cell Physiol (2010) 1.53

The Rho-Rock-Myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cells. PLoS One (2008) 1.52

Calcium-dependent neuroepithelial contractions expel damaged cells from the developing brain. Dev Cell (2014) 1.50

Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions. Mol Biol Cell (2007) 1.50

Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain (2009) 1.49

Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells. PLoS One (2010) 1.49

The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN. EMBO J (2007) 1.48

ROCK inhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells. Mol Reprod Dev (2009) 1.45

Regulation of RhoGEF proteins by G12/13-coupled receptors. Br J Pharmacol (2009) 1.45

Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR-/- mice. FASEB J (2008) 1.41

Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice. J Clin Invest (2010) 1.40

Elaborating polarity: PAR proteins and the cytoskeleton. Development (2011) 1.40

Rho-linked genes and neurological disorders. Pflugers Arch (2007) 1.39

Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions. Small GTPases (2014) 1.38

ROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinases. Neuroscientist (2007) 1.38

Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation. Cardiovasc Res (2009) 1.38

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and beta-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol (2007) 1.37

The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria. Nat Cell Biol (2009) 1.36

Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. Stem Cells (2009) 1.36

Phosphorylation of profilin by ROCK1 regulates polyglutamine aggregation. Mol Cell Biol (2008) 1.35

Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension. Br J Pharmacol (2008) 1.35

Isoform-specific contributions of alpha-actinin to glioma cell mechanobiology. PLoS One (2009) 1.34

ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency. PLoS One (2011) 1.34

Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system. J Cell Biol (2009) 1.33

Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. PLoS Med (2005) 1.32

Targeted disruption of ROCK1 causes insulin resistance in vivo. J Biol Chem (2009) 1.31

The genetics of pre-eclampsia and other hypertensive disorders of pregnancy. Best Pract Res Clin Obstet Gynaecol (2011) 1.31

Nonmuscle myosin-2: mix and match. Cell Mol Life Sci (2012) 1.30

The mammalian formin FHOD1 is activated through phosphorylation by ROCK and mediates thrombin-induced stress fibre formation in endothelial cells. EMBO J (2008) 1.28

Symmetry breaking and polarization of the C. elegans zygote by the polarity protein PAR-2. Development (2010) 1.28

The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol (2011) 1.28

A method for measuring Rho kinase activity in tissues and cells. Methods Enzymol (2008) 1.27

Thrombin promotes release of ATP from lung epithelial cells through coordinated activation of rho- and Ca2+-dependent signaling pathways. J Biol Chem (2009) 1.27

Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure. EMBO J (2008) 1.27

MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway. Carcinogenesis (2012) 1.27

ROCKs as therapeutic targets in cardiovascular diseases. Expert Rev Cardiovasc Ther (2005) 1.25

RHOA-FAK is a required signaling axis for the maintenance of KRAS-driven lung adenocarcinomas. Cancer Discov (2013) 1.25

Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil. J Cardiovasc Pharmacol (2013) 1.24

Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. Cancer Cell (2011) 1.24

RhoA/Rho-kinase and vascular diseases: what is the link? Cell Mol Life Sci (2010) 1.24

Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells. J Clin Invest (2010) 1.21

Individual cell movement, asymmetric colony expansion, rho-associated kinase, and E-cadherin impact the clonogenicity of human embryonic stem cells. Biophys J (2010) 1.21

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Blood (2009) 1.19

The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture. Nat Immunol (2014) 1.19

Rho overexpression leads to mitosis-associated detachment of cells from epithelial sheets: a link to the mechanism of cancer dissemination. Proc Natl Acad Sci U S A (2004) 1.19

Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease. Trends Pharmacol Sci (2011) 1.17

Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. Mol Biol Cell (2004) 1.17

Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration. Proc Natl Acad Sci U S A (2008) 1.17

MYBPH, a transcriptional target of TTF-1, inhibits ROCK1, and reduces cell motility and metastasis. EMBO J (2011) 1.17

Rho GTPase and Shroom direct planar polarized actomyosin contractility during convergent extension. J Cell Biol (2014) 1.16

Non-muscle myosin II regulates survival threshold of pluripotent stem cells. Nat Commun (2010) 1.16

P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts. J Cell Biol (2006) 1.16

Rho GTPases in platelet function. J Thromb Haemost (2013) 1.15

Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element. Mol Cell Biol (2006) 1.13

Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells. Blood (2007) 1.13

Emodin-induced generation of reactive oxygen species inhibits RhoA activation to sensitize gastric carcinoma cells to anoikis. Neoplasia (2008) 1.13

The R(h)oads to Stat3: Stat3 activation by the Rho GTPases. Exp Cell Res (2011) 1.12

Endosomes generate localized Rho-ROCK-MLC2-based contractile signals via Endo180 to promote adhesion disassembly. J Cell Biol (2006) 1.12

Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol (2008) 8.99

Rho GTPases in cancer cell biology. FEBS Lett (2008) 4.47

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. Nature (2008) 3.19

Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains. Nat Cell Biol (2006) 3.08

Rho GTPases and the regulation of endothelial permeability. Vascul Pharmacol (2002) 2.88

Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res (2004) 2.83

RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol (2011) 2.59

RhoE binds to ROCK I and inhibits downstream signaling. Mol Cell Biol (2003) 2.46

Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron (2011) 2.42

Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J Cell Biol (2003) 2.14

Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability. J Cell Physiol (2007) 2.03

Crossing the endothelial barrier during metastasis. Nat Rev Cancer (2013) 2.00

Phosphoinositide 3-kinases in cell migration. Biol Cell (2009) 1.95

14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins. Cell (2013) 1.90

Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J Cell Sci (2004) 1.88

Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein. J Biol Chem (2002) 1.88

Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology (2004) 1.82

IQGAP1 promotes cell motility and invasion. J Biol Chem (2003) 1.72

Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. J Cell Sci (2006) 1.70

Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins. Proc Natl Acad Sci U S A (2006) 1.64

Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis. Cancer Res (2002) 1.63

RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J (2005) 1.59

Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP. Mol Cell (2003) 1.53

Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol (2010) 1.52

Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells. PLoS One (2010) 1.49

The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN. EMBO J (2007) 1.48

RhoE inhibits cell cycle progression and Ras-induced transformation. Mol Cell Biol (2004) 1.41

Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages. J Cell Sci (2008) 1.39

RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Curr Biol (2006) 1.37

Rho GTPases and leukocyte adhesion receptor expression and function in endothelial cells. Circ Res (2006) 1.35

Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. J Cell Biol (2010) 1.35

Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis. Blood (2005) 1.34

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J Cell Sci (2008) 1.32

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol (2011) 1.30

The PI3K p110alpha isoform regulates endothelial adherens junctions via Pyk2 and Rac1. J Cell Biol (2010) 1.28

Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure. EMBO J (2008) 1.27

Intercellular adhesion molecule (ICAM)-1, but not ICAM-2, activates RhoA and stimulates c-fos and rhoA transcription in endothelial cells. J Immunol (2002) 1.25

Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1. Exp Cell Res (2003) 1.25

PAK4 is activated via PI3K in HGF-stimulated epithelial cells. J Cell Sci (2002) 1.24

Cell migration in development and disease. Dev Cell (2002) 1.23

Rnd proteins: multifunctional regulators of the cytoskeleton and cell cycle progression. Bioessays (2010) 1.21

Cdc42 promotes transendothelial migration of cancer cells through β1 integrin. J Cell Biol (2012) 1.20

Involvement of phosphoinositide 3-kinase gamma, Rac, and PAK signaling in chemokine-induced macrophage migration. J Biol Chem (2004) 1.20

Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation. Biochem J (2009) 1.19

p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulation. J Biol Chem (2003) 1.18

Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration. Proc Natl Acad Sci U S A (2008) 1.17

Cell motility: braking WAVEs. Nature (2002) 1.14

RhoB affects macrophage adhesion, integrin expression and migration. Exp Cell Res (2007) 1.13

T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice. J Clin Invest (2008) 1.13

Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering. J Biol Chem (2004) 1.12

Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages. J Biol Chem (2003) 1.11

PAK1 and PAK2 have different roles in HGF-induced morphological responses. Cell Signal (2009) 1.10

Extension, retraction and contraction in the formation of a dendritic cell dendrite: distinct roles for Rho GTPases. Eur J Immunol (2002) 1.10

SnapShot: Rho family GTPases. Cell (2007) 1.10

Rho GTPases and cell cycle control. Growth Factors (2006) 1.08

The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability. J Biol Chem (2003) 1.08

Rho GTPases and leucocyte-induced endothelial remodelling. Biochem J (2005) 1.07

Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms. Mol Biol Cell (2006) 1.07

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis. Blood (2011) 1.07

Rac activation by the T-cell receptor inhibits T cell migration. PLoS One (2010) 1.03

p120ctn and P-cadherin but not E-cadherin regulate cell motility and invasion of DU145 prostate cancer cells. PLoS One (2010) 1.02

Radixin regulates cell migration and cell-cell adhesion through Rac1. J Cell Sci (2012) 1.00

Analysis of cell migration using the Dunn chemotaxis chamber and time-lapse microscopy. Methods Mol Biol (2005) 0.98

Transcriptional regulation of the small GTPase RhoB gene by TGF{beta}-induced signaling pathways. FASEB J (2009) 0.95

Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1. J Biol Chem (2006) 0.94

Crosstalk between reticular adherens junctions and platelet endothelial cell adhesion molecule-1 regulates endothelial barrier function. Arterioscler Thromb Vasc Biol (2012) 0.94

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization. Exp Cell Res (2005) 0.94

CSF-1 and PI 3-kinase regulate podosome distribution and assembly in macrophages. Cell Motil Cytoskeleton (2006) 0.93

RhoB regulates cell migration through altered focal adhesion dynamics. Open Biol (2012) 0.93

Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin. FEBS Lett (2006) 0.93

Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing. J Biol Chem (2006) 0.92

RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation. J Biol Chem (2009) 0.91

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation. Exp Cell Res (2009) 0.90

In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin. J Biol Chem (2009) 0.90

RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific. Circ Res (2004) 0.89

T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue. Blood (2008) 0.89

Multiple roles for RhoA during T cell transendothelial migration. Small GTPases (2010) 0.88

Rho GTPases and cancer cell transendothelial migration. Methods Mol Biol (2012) 0.88

Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein. Biochemistry (2002) 0.88

FMNL1 promotes proliferation and migration of leukemia cells. J Leukoc Biol (2013) 0.87

Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b. J Leukoc Biol (2011) 0.87

RhoB regulates uPAR signalling. J Cell Sci (2012) 0.87

beta1-Integrins determine the dendritic morphology which enhances DC-SIGN-mediated particle capture by dendritic cells. Int Immunol (2006) 0.86

CD73 represses pro-inflammatory responses in human endothelial cells. J Inflamm (Lond) (2010) 0.85

Rnd3 induces stress fibres in endothelial cells through RhoB. Biol Open (2012) 0.85

Human endometrial stromal cell rho GTPases have opposing roles in regulating focal adhesion turnover and embryo invasion in vitro. Biol Reprod (2010) 0.85

Inhibition of ROCK by RhoE. Methods Enzymol (2006) 0.84

ARHGAP21 is a RhoGAP for RhoA and RhoC with a role in proliferation and migration of prostate adenocarcinoma cells. Biochim Biophys Acta (2012) 0.83

Quantification of transendothelial migration using three-dimensional confocal microscopy. Methods Mol Biol (2011) 0.83

MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression. Mol Biol Cell (2012) 0.83

Effects of microinjected small GTPases on the actin cytoskeleton of human neutrophils. J Anat (2003) 0.82

Getting invasive with GEP100 and Arf6. Nat Cell Biol (2008) 0.82

Roles of Rho GTPases in leucocyte and leukaemia cell transendothelial migration. Philos Trans R Soc Lond B Biol Sci (2013) 0.81

An in vitro model to study the role of endothelial rho GTPases during leukocyte transendothelial migration. Methods Enzymol (2006) 0.80

N-terminus-mediated dimerization of ROCK-I is required for RhoE binding and actin reorganization. Biochem J (2008) 0.80

Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration. Cytoskeleton (Hoboken) (2014) 0.80

Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration. Int J Biochem Cell Biol (2012) 0.79

Analyzing the roles of Rho GTPases in cancer cell migration with a live cell imaging 3D-morphology-based assay. Methods Mol Biol (2014) 0.78

RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress. Curr Biol (2016) 0.77

Using the Dunn chemotaxis chamber to analyze primary cell migration in real time. Methods Mol Biol (2011) 0.77