Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis.

PubWeight™: 1.45‹?› | Rank: Top 5%

🔗 View Article (PMC 165659)

Published in EMBO J on July 01, 2003

Authors

Hanjo Hellmann1, Lawrence Hobbie, Anngela Chapman, Sunethra Dharmasiri, Nihal Dharmasiri, Carlos del Pozo, Didier Reinhardt, Mark Estelle

Author Affiliations

1: Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA.

Articles citing this

Auxin: regulation, action, and interaction. Ann Bot (2005) 8.88

Ubiquitin, hormones and biotic stress in plants. Ann Bot (2007) 2.77

The ubiquitin-proteasome pathway and plant development. Plant Cell (2004) 2.72

The ubiquitin-proteasome system regulates plant hormone signaling. Plant J (2010) 1.63

Arabidopsis ETA2, an apparent ortholog of the human cullin-interacting protein CAND1, is required for auxin responses mediated by the SCF(TIR1) ubiquitin ligase. Plant Cell (2004) 1.58

yucca6, a dominant mutation in Arabidopsis, affects auxin accumulation and auxin-related phenotypes. Plant Physiol (2007) 1.57

Mutations in an auxin receptor homolog AFB5 and in SGT1b confer resistance to synthetic picolinate auxins and not to 2,4-dichlorophenoxyacetic acid or indole-3-acetic acid in Arabidopsis. Plant Physiol (2006) 1.54

Auxin signaling. Curr Opin Plant Biol (2006) 1.49

Genetic regulation of embryonic pattern formation. Plant Cell (2004) 1.41

SCFTIR1/AFB-based auxin perception: mechanism and role in plant growth and development. Plant Cell (2015) 1.35

Auxin perception--structural insights. Cold Spring Harb Perspect Biol (2010) 1.27

The ASK1 and ASK2 genes are essential for Arabidopsis early development. Plant Cell (2003) 1.26

Characterization of a novel temperature-sensitive allele of the CUL1/AXR6 subunit of SCF ubiquitin-ligases. Plant J (2005) 1.25

AtCAND1, a HEAT-repeat protein that participates in auxin signaling in Arabidopsis. Plant Physiol (2004) 1.21

A role for auxin response factor 19 in auxin and ethylene signaling in Arabidopsis. Plant Physiol (2006) 1.17

Related to ubiquitin 1 and 2 are redundant and essential and regulate vegetative growth, auxin signaling, and ethylene production in Arabidopsis. Plant Cell (2004) 1.15

Genetic analysis of CAND1-CUL1 interactions in Arabidopsis supports a role for CAND1-mediated cycling of the SCFTIR1 complex. Proc Natl Acad Sci U S A (2008) 1.12

A new CULLIN 1 mutant has altered responses to hormones and light in Arabidopsis. Plant Physiol (2006) 1.12

Auxin dynamics: the dazzling complexity of a small molecule's message. Planta (2008) 1.07

Analysis of the Arabidopsis rsr4-1/pdx1-3 mutant reveals the critical function of the PDX1 protein family in metabolism, development, and vitamin B6 biosynthesis. Plant Cell (2006) 1.04

Isolation and characterization of cul1-7, a recessive allele of CULLIN1 that disrupts SCF function at the C terminus of CUL1 in Arabidopsis thaliana. Genetics (2008) 1.00

The Arabidopsis F-box protein CORONATINE INSENSITIVE1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway. Plant Cell (2013) 0.97

Genetic characterization of mutants resistant to the antiauxin p-chlorophenoxyisobutyric acid reveals that AAR3, a gene encoding a DCN1-like protein, regulates responses to the synthetic auxin 2,4-dichlorophenoxyacetic acid in Arabidopsis roots. Plant Physiol (2007) 0.96

COP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis. J Biol Chem (2009) 0.96

Embryogenesis: pattern formation from a single cell. Arabidopsis Book (2009) 0.95

Regulation of flower development in Arabidopsis by SCF complexes. Plant Physiol (2004) 0.95

Mutation of E1-CONJUGATING ENZYME-RELATED1 decreases RELATED TO UBIQUITIN conjugation and alters auxin response and development. Plant Physiol (2007) 0.95

CUL1 regulates TOC1 protein stability in the Arabidopsis circadian clock. Plant J (2008) 0.93

Regulated proteolysis and plant development. Plant Cell Rep (2004) 0.89

HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1. Nat Commun (2016) 0.86

A mutation in the anticodon of a single tRNAala is sufficient to confer auxin resistance in Arabidopsis. Plant Physiol (2005) 0.86

Digital gene expression profiling by 5'-end sequencing of cDNAs during reprogramming in the moss Physcomitrella patens. PLoS One (2012) 0.85

Arabidopsis BPM proteins function as substrate adaptors to a cullin3-based E3 ligase to affect fatty acid metabolism in plants. Plant Cell (2013) 0.84

The NEDD8 modification pathway in plants. Front Plant Sci (2014) 0.83

The evolutionarily conserved TOUGH protein is required for proper development of Arabidopsis thaliana. Plant Cell (2005) 0.82

Knockdown of CELL DIVISION CYCLE16 reveals an inverse relationship between lateral root and nodule numbers and a link to auxin in Medicago truncatula. Plant Physiol (2009) 0.81

Rapid identification of angulata leaf mutations using next-generation sequencing. Planta (2014) 0.78

Role of HEMIVENATA and the Ubiquitin Pathway in Venation Pattern Formation. Plant Signal Behav (2007) 0.77

2,4-D and IAA Amino Acid Conjugates Show Distinct Metabolism in Arabidopsis. PLoS One (2016) 0.75

Composition, roles, and regulation of cullin-based ubiquitin e3 ligases. Arabidopsis Book (2014) 0.75

Change in Auxin and Cytokinin Levels Coincides with Altered Expression of Branching Genes during Axillary Bud Outgrowth in Chrysanthemum. PLoS One (2016) 0.75

A new temperature-insensitive allele of the Arabidopsis AXR6/CUL1 locus derived from a missense mutation in the C-terminal RBX1 binding region. Plant Signal Behav (2015) 0.75

New perspective on the stabilization and degradation of the F-box protein COI1 in Arabidopsis. Plant Signal Behav (2013) 0.75

Articles cited by this

Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J (1998) 97.93

Mechanisms underlying ubiquitination. Annu Rev Biochem (2001) 18.87

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature (2002) 10.96

SCF and Cullin/Ring H2-based ubiquitin ligases. Annu Rev Cell Dev Biol (1999) 9.54

Requirement of the Auxin Polar Transport System in Early Stages of Arabidopsis Floral Bud Formation. Plant Cell (1991) 9.38

Growth and development of the axr1 mutants of Arabidopsis. Plant Cell (1990) 8.73

Auxin regulates SCF(TIR1)-dependent degradation of AUX/IAA proteins. Nature (2001) 6.91

The Arabidopsis gene MONOPTEROS encodes a transcription factor mediating embryo axis formation and vascular development. EMBO J (1998) 6.03

Auxin regulates the initiation and radial position of plant lateral organs. Plant Cell (2000) 5.96

Auxin-responsive gene expression: genes, promoters and regulatory factors. Plant Mol Biol (2002) 5.02

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science (2001) 4.82

The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p. Genes Dev (1998) 4.72

Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes Dev (1999) 4.35

The roles of auxin response factor domains in auxin-responsive transcription. Plant Cell (2003) 4.19

Genetics of Aux/IAA and ARF action in plant growth and development. Plant Mol Biol (2002) 4.11

Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science (2001) 3.87

The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc Natl Acad Sci U S A (2002) 3.82

Ubiquitin-like proteins: new wines in new bottles. Gene (2000) 3.46

AUX/IAA proteins are active repressors, and their stability and activity are modulated by auxin. Plant Cell (2001) 3.42

The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis. Plant Cell (2002) 3.34

Studies on the role of the Arabidopsis gene MONOPTEROS in vascular development and plant cell axialization. Planta (1996) 3.34

Roles and activities of Aux/IAA proteins in Arabidopsis. Trends Plant Sci (2001) 3.29

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes Dev (1999) 3.11

The Arabidopsis BODENLOS gene encodes an auxin response protein inhibiting MONOPTEROS-mediated embryo patterning. Genes Dev (2002) 2.90

Auxin signaling in Arabidopsis leaf vascular development. Plant Physiol (2003) 2.75

Plant development: regulation by protein degradation. Science (2002) 2.64

The auxin-insensitive bodenlos mutation affects primary root formation and apical-basal patterning in the Arabidopsis embryo. Development (1999) 2.56

Auxin modulates the degradation rate of Aux/IAA proteins. Proc Natl Acad Sci U S A (2001) 2.54

The arabidopsis ATHB-8 HD-zip protein acts as a differentiation-promoting transcription factor of the vascular meristems. Plant Physiol (2001) 2.52

Rapid degradation of auxin/indoleacetic acid proteins requires conserved amino acids of domain II and is proteasome dependent. Plant Cell (2001) 2.50

The HOBBIT gene is required for formation of the root meristem in the Arabidopsis embryo. Development (1998) 2.48

The ubiquitin-related protein RUB1 and auxin response in Arabidopsis. Science (1998) 2.42

The axr6 mutants of Arabidopsis thaliana define a gene involved in auxin response and early development. Development (2000) 2.12

Localized upregulation of a new expansin gene predicts the site of leaf formation in the tomato meristem. Plant Cell (1998) 2.11

The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1. Mol Cell Biol (2000) 2.09

AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response. Plant Cell (2002) 2.09

An Arabidopsis mutant defective in jasmonate response is allelic to the auxin-signaling mutant axr1. Plant Physiol (2002) 2.01

SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase. EMBO J (2001) 1.83

Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis. Mol Biol Cell (2002) 1.78

Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function. Plant Cell (2002) 1.66

Classification and expression analysis of Arabidopsis F-box-containing protein genes. Plant Cell Physiol (2002) 1.59

The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. EMBO J (2003) 1.50

The Arabidopsis HOBBIT gene encodes a CDC27 homolog that links the plant cell cycle to progression of cell differentiation. Genes Dev (2002) 1.48

Auxin and phyllotaxis. Trends Plant Sci (2001) 1.23

Culprits in the degradation of cyclin E apprehended. Genes Dev (1999) 0.98

Articles by these authors

The F-box protein TIR1 is an auxin receptor. Nature (2005) 9.45

Mechanism of auxin perception by the TIR1 ubiquitin ligase. Nature (2007) 8.21

The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants. Science (2007) 8.12

A plant miRNA contributes to antibacterial resistance by repressing auxin signaling. Science (2006) 7.74

Plant development is regulated by a family of auxin receptor F box proteins. Dev Cell (2005) 5.54

A plausible model of phyllotaxis. Proc Natl Acad Sci U S A (2006) 4.31

Recent advances and emerging trends in plant hormone signalling. Nature (2009) 3.32

Auxin receptors and plant development: a new signaling paradigm. Annu Rev Cell Dev Biol (2008) 3.21

Mechanism of auxin-regulated gene expression in plants. Annu Rev Genet (2009) 3.11

The Selaginella genome identifies genetic changes associated with the evolution of vascular plants. Science (2011) 3.10

Sites and regulation of auxin biosynthesis in Arabidopsis roots. Plant Cell (2005) 2.94

The auxin signalling network translates dynamic input into robust patterning at the shoot apex. Mol Syst Biol (2011) 2.74

The ubiquitin-proteasome pathway and plant development. Plant Cell (2004) 2.72

Plant development: regulation by protein degradation. Science (2002) 2.64

Fluorine in pharmaceutical industry: fluorine-containing drugs introduced to the market in the last decade (2001-2011). Chem Rev (2013) 2.38

A combinatorial TIR1/AFB-Aux/IAA co-receptor system for differential sensing of auxin. Nat Chem Biol (2012) 2.18

Auxin signaling and regulated protein degradation. Trends Plant Sci (2004) 2.15

AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response. Plant Cell (2002) 2.09

Phosphate availability alters lateral root development in Arabidopsis by modulating auxin sensitivity via a mechanism involving the TIR1 auxin receptor. Plant Cell (2008) 2.08

Auxin action in a cell-free system. Curr Biol (2003) 1.93

Elastic domains regulate growth and organogenesis in the plant shoot apical meristem. Science (2012) 1.91

Plant hormones are versatile chemical regulators of plant growth. Nat Chem Biol (2009) 1.89

Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Plant J (2003) 1.89

Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis. Mol Biol Cell (2002) 1.78

The TRANSPORT INHIBITOR RESPONSE2 gene is required for auxin synthesis and diverse aspects of plant development. Plant Physiol (2009) 1.70

Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function. Plant Cell (2002) 1.66

The IAA1 protein is encoded by AXR5 and is a substrate of SCF(TIR1). Plant J (2004) 1.63

The ubiquitin-proteasome system regulates plant hormone signaling. Plant J (2010) 1.63

The role of regulated protein degradation in auxin response. Plant Mol Biol (2002) 1.56

Auxin receptors: a new role for F-box proteins. Curr Opin Cell Biol (2006) 1.55

Cullins 3a and 3b assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases (E3s) in Arabidopsis. J Biol Chem (2005) 1.52

The Arabidopsis SUPPRESSOR OF AUXIN RESISTANCE proteins are nucleoporins with an important role in hormone signaling and development. Plant Cell (2006) 1.52

The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. EMBO J (2003) 1.50

Phosphate systemically inhibits development of arbuscular mycorrhiza in Petunia hybrida and represses genes involved in mycorrhizal functioning. Plant J (2010) 1.50

A petunia ABC protein controls strigolactone-dependent symbiotic signalling and branching. Nature (2012) 1.44

Retracted The AFB4 auxin receptor is a negative regulator of auxin signaling in seedlings. Curr Biol (2011) 1.36

Nitric oxide influences auxin signaling through S-nitrosylation of the Arabidopsis TRANSPORT INHIBITOR RESPONSE 1 auxin receptor. Plant J (2012) 1.35

Starch granule biosynthesis in Arabidopsis is abolished by removal of all debranching enzymes but restored by the subsequent removal of an endoamylase. Plant Cell (2008) 1.34

Regulation of cullin-based ubiquitin ligases by the Nedd8/RUB ubiquitin-like proteins. Semin Cell Dev Biol (2004) 1.29

New auxin analogs with growth-promoting effects in intact plants reveal a chemical strategy to improve hormone delivery. Proc Natl Acad Sci U S A (2008) 1.27

Auxin perception--structural insights. Cold Spring Harb Perspect Biol (2010) 1.27

The impact of Arabidopsis on human health: diversifying our portfolio. Cell (2008) 1.27

The plant multidrug resistance ABC transporter AtMRP5 is involved in guard cell hormonal signalling and water use. Plant J (2003) 1.24

Arabidopsis AtCUL3a and AtCUL3b form complexes with members of the BTB/POZ-MATH protein family. Plant Physiol (2004) 1.23

Root gravitropism is regulated by a transient lateral auxin gradient controlled by a tipping-point mechanism. Proc Natl Acad Sci U S A (2012) 1.22

Gibberellins accumulate in the elongating endodermal cells of Arabidopsis root. Proc Natl Acad Sci U S A (2013) 1.16

Hypocotyl transcriptome reveals auxin regulation of growth-promoting genes through GA-dependent and -independent pathways. PLoS One (2012) 1.15

Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response. Plant J (2005) 1.15

Regulation of auxin homeostasis and gradients in Arabidopsis roots through the formation of the indole-3-acetic acid catabolite 2-oxindole-3-acetic acid. Plant Cell (2013) 1.15

Physcomitrella patens auxin-resistant mutants affect conserved elements of an auxin-signaling pathway. Curr Biol (2010) 1.14

The Arabidopsis D-type cyclin CYCD2;1 and the inhibitor ICK2/KRP2 modulate auxin-induced lateral root formation. Plant Cell (2011) 1.14

The auxin influx carrier is essential for correct leaf positioning. Plant J (2002) 1.13

A new CULLIN 1 mutant has altered responses to hormones and light in Arabidopsis. Plant Physiol (2006) 1.12

Degradation of the cyclin-dependent kinase inhibitor KRP1 is regulated by two different ubiquitin E3 ligases. Plant J (2007) 1.10

Microwave-assisted tandem cross metathesis intramolecular Aza-Michael reaction: an easy entry to cyclic beta-amino carbonyl derivatives. J Am Chem Soc (2007) 1.01

Ubiquitin-mediated control of plant hormone signaling. Plant Physiol (2012) 0.99

Flying saucer1 is a transmembrane RING E3 ubiquitin ligase that regulates the degree of pectin methylesterification in Arabidopsis seed mucilage. Plant Cell (2013) 0.97

Mutations in the TIR1 auxin receptor that increase affinity for auxin/indole-3-acetic acid proteins result in auxin hypersensitivity. Plant Physiol (2013) 0.97

Regulation of flower development in Arabidopsis by SCF complexes. Plant Physiol (2004) 0.95

A map of cell type-specific auxin responses. Mol Syst Biol (2013) 0.95

SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway. Plant J (2007) 0.94

The PAM1 gene of petunia, required for intracellular accommodation and morphogenesis of arbuscular mycorrhizal fungi, encodes a homologue of VAPYRIN. Plant J (2010) 0.94

A petunia chorismate mutase specialized for the production of floral volatiles. Plant J (2009) 0.93

A transgenic dTph1 insertional mutagenesis system for forward genetics in mycorrhizal phosphate transport of Petunia. Plant J (2008) 0.92

ENTIRE and GOBLET promote leaflet development in tomato by modulating auxin response. Plant J (2012) 0.91

High resolution linkage maps of the model organism Petunia reveal substantial synteny decay with the related genome of tomato. Genome (2011) 0.88

Total synthesis of natural myriaporones. Angew Chem Int Ed Engl (2004) 0.86

Successful joint ventures of plants: arbuscular mycorrhiza and beyond. Trends Plant Sci (2011) 0.86

The JAZ proteins link jasmonate perception with transcriptional changes. Plant Cell (2007) 0.86

How membranes shape plant symbioses: signaling and transport in nodulation and arbuscular mycorrhiza. Front Plant Sci (2012) 0.85

ROOT ULTRAVIOLET B-SENSITIVE1/weak auxin response3 is essential for polar auxin transport in Arabidopsis. Plant Physiol (2013) 0.85

A petunia mutant affected in intracellular accommodation and morphogenesis of arbuscular mycorrhizal fungi. Plant J (2007) 0.85

The cyclophilin DIAGEOTROPICA has a conserved role in auxin signaling. Development (2012) 0.84

AuX3-mediated selective head-to-head dimerization of difluoropropargyl amides. J Org Chem (2009) 0.83

Complex thyroid nodules with nondiagnostic fine needle aspiration cytology: histopathologic outcomes and comparison of the cytologic variants (cystic vs. acellular). Endocrine (2010) 0.82

Auxin perception: in the IAA of the beholder. Physiol Plant (2014) 0.82

Fluorous (trimethylsilyl)ethanol: a new reagent for carboxylic acid tagging and protection in peptide synthesis. J Org Chem (2006) 0.82

Integrating transcriptional controls for plant cell expansion. Genome Biol (2004) 0.82

N-sulfinyl amines as a nitrogen source in the asymmetric intramolecular aza-Michael reaction: total synthesis of (-)-pinidinol. Chemistry (2010) 0.81

1,7-octadiene-assisted tandem multicomponent cross-enyne metathesis (CEYM)-Diels-Alder reactions: a useful alternative to Mori's conditions. Chemistry (2012) 0.81

1,4-Benzodiazepine N-nitrosoamidines: useful intermediates in the synthesis of tricyclic benzodiazepines. Molecules (2006) 0.81

A novel bioinformatics pipeline to discover genes related to arbuscular mycorrhizal symbiosis based on their evolutionary conservation pattern among higher plants. BMC Plant Biol (2014) 0.80

Tandem asymmetric Michael reaction-intramolecular Michael addition. An easy entry to chiral fluorinated 1,4-dihydropyridines. Org Lett (2010) 0.80

Synthesis of enantiopure pyrrolidine-derived peptidomimetics and oligo-beta-peptides via nucleophilic ring-opening of beta-lactams. J Org Chem (2006) 0.79

Asymmetric synthesis of indolines through intramolecular shifting of aromatic sulfinyl groups. Role of the pi,pi-stacking interactions in these unusual S(N)Ar processes. J Am Chem Soc (2009) 0.78

Tandem gold self-relay catalysis for the synthesis of 2,3-dihydropyridin-4(1 H)-ones: combination of σ and π Lewis acid properties of gold salts. Chemistry (2014) 0.78