Published in J Cell Sci on July 02, 2003
The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A (2007) 4.01
Life cycle of connexins in health and disease. Biochem J (2006) 3.44
Connexin43 phosphorylation: structural changes and biological effects. Biochem J (2009) 2.75
Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. J Clin Invest (2006) 1.22
Specific Cx43 phosphorylation events regulate gap junction turnover in vivo. FEBS Lett (2014) 1.19
Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368. J Cell Biol (2004) 1.18
Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics. PLoS One (2011) 1.05
Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells. J Cell Mol Med (2011) 0.97
GJB2 Gene Mutations in Syndromic Skin Diseases with Sensorineural Hearing Loss. Curr Genomics (2011) 0.96
Cardiac to cancer: connecting connexins to clinical opportunity. FEBS Lett (2014) 0.96
CASK (LIN2) interacts with Cx43 in wounded skin and their coexpression affects cell migration. J Cell Sci (2012) 0.93
Temporal regulation of connexin phosphorylation in embryonic and adult tissues. Biochim Biophys Acta (2005) 0.92
Gap junctions and blood-tissue barriers. Adv Exp Med Biol (2012) 0.92
Targeting Cx43 and N-cadherin, which are abnormally upregulated in venous leg ulcers, influences migration, adhesion and activation of Rho GTPases. PLoS One (2012) 0.90
Human dermal fibroblasts derived from oculodentodigital dysplasia patients suggest that patients may have wound-healing defects. Hum Mutat (2011) 0.88
Expression and function of connexin 43 in human gingival wound healing and fibroblasts. PLoS One (2015) 0.84
The potency of the fs260 connexin43 mutant to impair keratinocyte differentiation is distinct from other disease-linked connexin43 mutants. Biochem J (2010) 0.84
The adhesion modulating properties of tenascin-W. Int J Biol Sci (2011) 0.81
A Snapshot of Direct Cell-Cell Communications in Wound Healing and Scarring. Adv Wound Care (New Rochelle) (2013) 0.80
Connexin hemichannels influence genetically determined inflammatory and hyperproliferative skin diseases. Pharmacol Res (2015) 0.79
Connexin channels in congenital skin disorders. Semin Cell Dev Biol (2016) 0.79
Helicobacter pylori VacA induces apoptosis by accumulation of connexin 43 in autophagic vesicles via a Rac1/ERK-dependent pathway. Cell Death Discov (2015) 0.78
Connexin 43 deficiency accelerates skin wound healing and extracellular matrix remodeling in mice. J Dermatol Sci (2015) 0.78
GATA-3 augmentation down-regulates Connexin43 in Helicobacter pylori associated gastric carcinogenesis. Cancer Biol Ther (2015) 0.77
Differentiation of organotypic epidermis in the presence of skin disease-linked dominant-negative Cx26 mutants and knockdown Cx26. J Membr Biol (2007) 0.77
Kinase programs spatiotemporally regulate gap junction assembly and disassembly: Effects on wound repair. Semin Cell Dev Biol (2015) 0.76
The Role of Connexins in Wound Healing and Repair: Novel Therapeutic Approaches. Front Physiol (2016) 0.76
Human diseases associated with connexin mutations. Biochim Biophys Acta (2017) 0.75
Effect of connexin 43 inhibition by the mimetic peptide Gap27 on corneal wound healing, inflammation and neovascularization. Br J Pharmacol (2016) 0.75
Cell coupling mediated by connexin 26 selectively contributes to reduced adhesivity and increased migration. J Cell Sci (2016) 0.75
Connexin 43: Key roles in the skin. Biomed Rep (2017) 0.75
Structural and functional diversity of connexin genes in the mouse and human genome. Biol Chem (2002) 5.40
Gap junctions and the connexin protein family. Cardiovasc Res (2004) 3.66
Astroglial metabolic networks sustain hippocampal synaptic transmission. Science (2008) 3.49
Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia. Nature (2007) 3.46
A gene expression atlas of the model legume Medicago truncatula. Plant J (2008) 3.38
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat Cell Biol (2011) 3.25
Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proc Natl Acad Sci U S A (2001) 3.17
Expression and functions of neuronal gap junctions. Nat Rev Neurosci (2005) 2.91
The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. J Neurosci (2006) 2.85
Targeted ablation of connexin26 in the inner ear epithelial gap junction network causes hearing impairment and cell death. Curr Biol (2002) 2.72
MtHAP2-1 is a key transcriptional regulator of symbiotic nodule development regulated by microRNA169 in Medicago truncatula. Genes Dev (2006) 2.41
Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release. Diabetes (2005) 2.24
Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circulation (2004) 2.23
Connexin30 (Gjb6)-deficiency causes severe hearing impairment and lack of endocochlear potential. Hum Mol Genet (2003) 2.17
Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43. J Cell Sci (2006) 2.06
Global changes in transcription orchestrate metabolic differentiation during symbiotic nitrogen fixation in Lotus japonicus. Plant J (2004) 1.99
Remorin, a solanaceae protein resident in membrane rafts and plasmodesmata, impairs potato virus X movement. Plant Cell (2009) 1.91
Connexin hemichannel-mediated CO2-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity. J Physiol (2010) 1.81
An update on connexin genes and their nomenclature in mouse and man. Cell Commun Adhes (2003) 1.77
Cardiomyocyte-restricted deletion of connexin43 during mouse development. J Mol Cell Cardiol (2006) 1.70
Role of olivary electrical coupling in cerebellar motor learning. Neuron (2008) 1.67
Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem Cells (2009) 1.63
Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J Neurosci (2002) 1.62
A remorin protein interacts with symbiotic receptors and regulates bacterial infection. Proc Natl Acad Sci U S A (2010) 1.61
The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans. Hum Mol Genet (2007) 1.61
Accelerated hippocampal spreading depression and enhanced locomotory activity in mice with astrocyte-directed inactivation of connexin43. J Neurosci (2003) 1.59
Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas. J Biol Chem (2009) 1.58
A central role of connexin 43 in hypoxic preconditioning. J Neurosci (2008) 1.56
Functional properties of mouse connexin30.2 expressed in the conduction system of the heart. Circ Res (2005) 1.54
Connexin43 interacts with NOV: a possible mechanism for negative regulation of cell growth in choriocarcinoma cells. J Biol Chem (2004) 1.50
Connexin 47 (Cx47)-deficient mice with enhanced green fluorescent protein reporter gene reveal predominant oligodendrocytic expression of Cx47 and display vacuolized myelin in the CNS. J Neurosci (2003) 1.48
C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques. Circ Res (2007) 1.46
The connexin 40 A96S mutation causes renin-dependent hypertension. J Am Soc Nephrol (2011) 1.46
Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate. Cardiovasc Res (2010) 1.45
Cardiac morphogenetic defects and conduction abnormalities in mice homozygously deficient for connexin40 and heterozygously deficient for connexin45. J Mol Cell Cardiol (2006) 1.45
Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness. Proc Natl Acad Sci U S A (2007) 1.44
Extracellular Ca²⁺ acts as a mediator of communication from neurons to glia. Sci Signal (2012) 1.42
Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level. J Neurosci (2003) 1.41
Gating properties of heterotypic gap junction channels formed of connexins 40, 43, and 45. Biophys J (2006) 1.40
Connexin mediates gap junction-independent resistance to cellular injury. J Neurosci (2003) 1.38
The sulfate transporter SST1 is crucial for symbiotic nitrogen fixation in Lotus japonicus root nodules. Plant Cell (2005) 1.38
Dissection of symbiosis and organ development by integrated transcriptome analysis of lotus japonicus mutant and wild-type plants. PLoS One (2009) 1.38
Functional expression of connexin57 in horizontal cells of the mouse retina. Eur J Neurosci (2004) 1.38
Connexin 30 deficiency impairs renal tubular ATP release and pressure natriuresis. J Am Soc Nephrol (2009) 1.37
Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission. J Neurosci (2005) 1.34
Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. J Biol Chem (2004) 1.34
Protein kinase A-mediated phosphorylation of connexin36 in mouse retina results in decreased gap junctional communication between AII amacrine cells. J Biol Chem (2006) 1.33
Properties of mouse connexin 30.2 and human connexin 31.9 hemichannels: implications for atrioventricular conduction in the heart. Proc Natl Acad Sci U S A (2006) 1.32
Defective epidermal barrier in neonatal mice lacking the C-terminal region of connexin43. Mol Biol Cell (2004) 1.31
Emerging complexities in identity and function of glial connexins. Trends Neurosci (2005) 1.31
Reduction of high-frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36-deficient mice. J Physiol (2002) 1.30
Genome-wide annotation of remorins, a plant-specific protein family: evolutionary and functional perspectives. Plant Physiol (2007) 1.30
Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endothelium. BMC Med (2008) 1.29
The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors. Proc Natl Acad Sci U S A (2008) 1.28
Increased apoptosis and inflammation after focal brain ischemia in mice lacking connexin43 in astrocytes. Am J Pathol (2004) 1.28
Connexin-caused genetic diseases and corresponding mouse models. Antioxid Redox Signal (2009) 1.27
Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet (2011) 1.26
Connexin36 mediates gap junctional coupling of alpha-ganglion cells in mouse retina. J Comp Neurol (2005) 1.26
Involvement of the cytoplasmic C-terminal domain of connexin43 in neuronal migration. J Neurosci (2009) 1.23
Selective permeability of different connexin channels to the second messenger cyclic AMP. J Biol Chem (2005) 1.23
Human connexin26 (GJB2) deafness mutations affect the function of gap junction channels at different levels of protein expression. Hum Genet (2002) 1.23
Expression pattern of lacZ reporter gene representing connexin36 in transgenic mice. J Comp Neurol (2004) 1.22
Distinct types of astroglial cells in the hippocampus differ in gap junction coupling. Glia (2004) 1.21
Pharmacological sensitivity of ATP release triggered by photoliberation of inositol-1,4,5-trisphosphate and zero extracellular calcium in brain endothelial cells. J Cell Physiol (2003) 1.21
Essential myosin light chain as a target for caspase-3 in failing myocardium. Proc Natl Acad Sci U S A (2002) 1.21
A sertoli cell-specific knockout of connexin43 prevents initiation of spermatogenesis. Am J Pathol (2007) 1.20
Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves. Cereb Cortex (2005) 1.20
Some oculodentodigital dysplasia-associated Cx43 mutations cause increased hemichannel activity in addition to deficient gap junction channels. J Membr Biol (2007) 1.20
Expression of connexins during differentiation and regeneration of skeletal muscle: functional relevance of connexin43. J Cell Sci (2004) 1.19
Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J Neurosci (2004) 1.18
Connexin expression by radial glia-like cells is required for neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A (2009) 1.17
Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node. Proc Natl Acad Sci U S A (2006) 1.17
Horizontal cell receptive fields are reduced in connexin57-deficient mice. Eur J Neurosci (2006) 1.14
Connexin45 mediates gap junctional coupling of bistratified ganglion cells in the mouse retina. J Comp Neurol (2005) 1.13
The role of neuronal connexins 36 and 45 in shaping spontaneous firing patterns in the developing retina. J Neurosci (2011) 1.11
Ablation of connexin43 in uterine smooth muscle cells of the mouse causes delayed parturition. J Cell Sci (2006) 1.11
Localization of heterotypic gap junctions composed of connexin45 and connexin36 in the rod pathway of the mouse retina. Eur J Neurosci (2006) 1.11
Connexin-mediated cardiac impulse propagation: connexin 30.2 slows atrioventricular conduction in mouse heart. Trends Cardiovasc Med (2006) 1.10
Oligodendrocytes in mouse corpus callosum are coupled via gap junction channels formed by connexin47 and connexin32. Glia (2010) 1.10
A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells. Exp Cell Res (2008) 1.09
Gating, permselectivity and pH-dependent modulation of channels formed by connexin57, a major connexin of horizontal cells in the mouse retina. J Physiol (2009) 1.08
Perspectives on remorin proteins, membrane rafts, and their role during plant-microbe interactions. Mol Plant Microbe Interact (2011) 1.08
Ganglion cell adaptability: does the coupling of horizontal cells play a role? PLoS One (2008) 1.07
The human deafness-associated connexin 30 T5M mutation causes mild hearing loss and reduces biochemical coupling among cochlear non-sensory cells in knock-in mice. Hum Mol Genet (2010) 1.07
Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets. Exp Cell Res (2004) 1.06
Transcription reprogramming during root nodule development in Medicago truncatula. PLoS One (2011) 1.05