Published in PLoS One on May 15, 2012
The effect of a connexin43-based Peptide on the healing of chronic venous leg ulcers: a multicenter, randomized trial. J Invest Dermatol (2014) 1.53
ERBB4 confers metastatic capacity in Ewing sarcoma. EMBO Mol Med (2013) 1.05
Cardiac to cancer: connecting connexins to clinical opportunity. FEBS Lett (2014) 0.96
Absence of venous valves in mice lacking Connexin37. Dev Biol (2012) 0.84
Embryonic wound healing: a primer for engineering novel therapies for tissue repair. Birth Defects Res C Embryo Today (2012) 0.82
Mind the gap: connexins and cell-cell communication in the diabetic kidney. Diabetologia (2014) 0.77
The Role of Connexins in Wound Healing and Repair: Novel Therapeutic Approaches. Front Physiol (2016) 0.76
Specific functional pathologies of Cx43 mutations associated with oculodentodigital dysplasia. Mol Biol Cell (2016) 0.76
The assembly of developing motor neurons depends on an interplay between spontaneous activity, type II cadherins and gap junctions. Development (2017) 0.75
Reduction in gap junction intercellular communication promotes glioma migration. Oncotarget (2015) 0.75
Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia. PLoS One (2015) 0.75
Connexin 43: Key roles in the skin. Biomed Rep (2017) 0.75
Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol (2005) 16.77
Human skin wounds: a major and snowballing threat to public health and the economy. Wound Repair Regen (2009) 7.29
Spatiotemporal dynamics of RhoA activity in migrating cells. Nature (2006) 6.84
Coordination of Rho GTPase activities during cell protrusion. Nature (2009) 6.54
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol Cell Biol (2002) 4.50
Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell (2007) 3.52
Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells. J Cell Sci (1995) 3.27
The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 protein. Curr Biol (1998) 2.80
Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion. Mol Biol Cell (2005) 2.62
Selective stabilization of microtubules oriented toward the direction of cell migration. Proc Natl Acad Sci U S A (1988) 2.52
Connexins and cell signaling in development and disease. Annu Rev Cell Dev Biol (2004) 2.25
Gap junction protein connexin-43 interacts directly with microtubules. Curr Biol (2001) 1.76
Connexin 43 enhances the adhesivity and mediates the invasion of malignant glioma cells. J Neurosci (2002) 1.62
Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing. J Invest Dermatol (2004) 1.61
Connexin43 associated with an N-cadherin-containing multiprotein complex is required for gap junction formation in NIH3T3 cells. J Biol Chem (2005) 1.59
Microtubule involvement in NIH 3T3 Golgi and MTOC polarity establishment. J Cell Sci (2003) 1.58
Imaging of single light-responsive clock cells reveals fluctuating free-running periods. Nat Cell Biol (2005) 1.51
Targeting connexin43 expression accelerates the rate of wound repair. Curr Biol (2003) 1.48
Cadherins promote skeletal muscle differentiation in three-dimensional cultures. J Cell Biol (1997) 1.47
Glucocorticoids regulate transendothelial fluid flow resistance and formation of intercellular junctions. Am J Physiol (1999) 1.46
Drebrin is a novel connexin-43 binding partner that links gap junctions to the submembrane cytoskeleton. Curr Biol (2004) 1.41
A specialized wound-healing center concept: importance of a multidisciplinary department structure and surgical treatment facilities in the treatment of chronic wounds. Am J Surg (2004) 1.41
Novel therapies for scar reduction and regenerative healing of skin wounds. Trends Biotechnol (2008) 1.38
Gap junction-mediated cell-cell communication modulates mouse neural crest migration. J Cell Biol (1998) 1.37
Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration. J Cell Sci (2006) 1.36
Connexin 43-mediated modulation of polarized cell movement and the directional migration of cardiac neural crest cells. Development (2006) 1.27
Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate. J Cell Biol (2007) 1.25
Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells. Blood (2010) 1.25
Altered connexin expression and wound healing in the epidermis of connexin-deficient mice. J Cell Sci (2003) 1.20
Abnormal connexin expression underlies delayed wound healing in diabetic skin. Diabetes (2007) 1.20
Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368. J Cell Biol (2004) 1.18
Involvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound models. Mol Biol Cell (2003) 1.15
The cytoplasmic face of cell contact sites. Curr Opin Struct Biol (2002) 1.14
Adhesive properties of connexin hemichannels. Glia (2008) 1.14
Functional analysis of amino acid sequences in connexin43 involved in intercellular communication through gap junctions. J Cell Sci (1995) 1.13
Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication. Mol Biol Cell (1995) 1.12
Dynamic changes in connexin expression correlate with key events in the wound healing process. Cell Biol Int (2003) 1.11
Connexin43 carboxyl-terminal peptides reduce scar progenitor and promote regenerative healing following skin wounding. Regen Med (2009) 1.09
Connexin43 knockdown accelerates wound healing but inhibits mesenchymal transition after corneal endothelial injury in vivo. Invest Ophthalmol Vis Sci (2008) 1.09
PAR1b promotes cell-cell adhesion and inhibits dishevelled-mediated transformation of Madin-Darby canine kidney cells. Mol Biol Cell (2006) 1.07
Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics. PLoS One (2011) 1.05
Zonula occludens-1 (ZO-1) is involved in morula to blastocyst transformation in the mouse. Dev Biol (2008) 1.04
Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia. J Biol Chem (2004) 1.02
Connexin mimetic peptides improve cell migration rates of human epidermal keratinocytes and dermal fibroblasts in vitro. Wound Repair Regen (2009) 1.02
Changes in the expression of gap junction proteins (connexins) in hamster tongue epithelium during wound healing and carcinogenesis. Carcinogenesis (1997) 0.99
Abeta1-42 stimulates actin polymerization in hippocampal neurons through Rac1 and Cdc42 Rho GTPases. J Cell Sci (2007) 0.97
Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells. J Cell Mol Med (2011) 0.97
N-Cadherin inhibits Schwann cell migration on astrocytes. Mol Cell Neurosci (1999) 0.95
E-cadherin suppression directs cytoskeletal rearrangement and intraepithelial tumor cell migration in 3D human skin equivalents. J Invest Dermatol (2008) 0.94
Limiting burn extension by transient inhibition of Connexin43 expression at the site of injury. Br J Plast Surg (2005) 0.93
Expression and function of connexins in the epidermis, analyzed with transgenic mouse mutants. Eur J Cell Biol (2004) 0.92
Microinjected anti-actin antibodies decrease gap junctional intercellular commmunication in cultured astrocytes. Exp Cell Res (2002) 0.90
The unstoppable connexin43 carboxyl-terminus: new roles in gap junction organization and wound healing. Ann N Y Acad Sci (2006) 0.89
ZO-1: lamellipodial localization in a corneal fibroblast wound model. Invest Ophthalmol Vis Sci (2005) 0.88
Fine structural differentiation of germ layers in the mouse at the time of mesoderm formation. Anat Rec (1979) 0.86
E-cadherin differentially regulates the assembly of Connexin43 and Connexin32 into gap junctions in human squamous carcinoma cells. J Biol Chem (2010) 0.86
Gap junction intercellular communication in gliomas is inversely related to cell motility. Int J Dev Neurosci (1999) 0.85
Gap-junctional protein connexin 43 is expressed in dermis and epidermis of human skin: differential modulation by retinoids. J Invest Dermatol (1992) 0.83
Role of gap junctions in the development of the preimplantation mouse embryo. Microsc Res Tech (1995) 0.81
Use of pIRES vectors to express EGFP and connexin constructs in studies of the role of gap junctional communication in the early development of the chick retina and brain. Cell Commun Adhes (2001) 0.81
Organ failure and infection of pancreatic necrosis as determinants of mortality in patients with acute pancreatitis. Gastroenterology (2010) 1.88
Guidelines for the treatment of diabetic ulcers. Wound Repair Regen (2007) 1.67
Additive effect of pretransplant obesity, diabetes, and cardiovascular risk factors on outcomes after liver transplantation. Liver Transpl (2014) 1.53
Targeting connexin43 expression accelerates the rate of wound repair. Curr Biol (2003) 1.48
Redox status of acute pancreatitis as measured by cyclic voltammetry: initial rodent studies to assess disease severity. Crit Care Med (2008) 1.39
Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration. J Cell Sci (2006) 1.36
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Aging Cell (2012) 1.35
Second harmonic generation confocal microscopy of collagen type I from rat tendon cryosections. Biophys J (2006) 1.33
A novel role for Wnt/Ca2+ signaling in actin cytoskeleton remodeling and cell motility in prostate cancer. PLoS One (2010) 1.26
Mutations in the gene for connexin 26 (GJB2) that cause hearing loss have a dominant negative effect on connexin 30. Hum Mol Genet (2003) 1.25
Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells. J Neurosci (2005) 1.24
Transcriptomic analysis of the cardiac left ventricle in a rodent model of diabetic cardiomyopathy: molecular snapshot of a severe myocardial disease. Physiol Genomics (2006) 1.21
Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitro. Biol Reprod (2004) 1.20
Abnormal connexin expression underlies delayed wound healing in diabetic skin. Diabetes (2007) 1.20
Newly diagnosed diabetes mellitus after acute pancreatitis: a systematic review and meta-analysis. Gut (2013) 1.20
A systematic review of experimental treatments for mitochondrial dysfunction in sepsis and multiple organ dysfunction syndrome. Free Radic Biol Med (2009) 1.19
Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury. Mol Cell Neurosci (2008) 1.16
Three-colour fluorescence immunohistochemistry reveals the diversity of cells staining for macrophage markers in murine spleen and liver. J Immunol Methods (2008) 1.13
Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system. Eur J Neurosci (2008) 1.12
The inner ear contains heteromeric channels composed of cx26 and cx30 and deafness-related mutations in cx26 have a dominant negative effect on cx30. Cell Commun Adhes (2003) 1.04
Regeneration of the heart in diabetes by selective copper chelation. Diabetes (2004) 1.04
Quantification of retinal transneuronal degeneration in human glaucoma: a novel multiphoton-DAPI approach. Invest Ophthalmol Vis Sci (2008) 1.03
Electric field effects on human spinal injury: Is there a basis in the in vitro studies? Dev Neurobiol (2008) 1.02
The proteome of rodent mesenteric lymph. Am J Physiol Gastrointest Liver Physiol (2008) 1.00
Altered calcium homeostasis does not explain the contractile deficit of diabetic cardiomyopathy. Diabetes (2008) 0.99
Changes in the mesenteric lymph proteome induced by hemorrhagic shock. Shock (2010) 0.97
ProNGF, sortilin, and age-related neurodegeneration. Ann N Y Acad Sci (2007) 0.97
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation. J Immunol (2011) 0.97
Guidelines for the prevention of diabetic ulcers. Wound Repair Regen (2008) 0.96
Connexins in wound healing; perspectives in diabetic patients. Biochim Biophys Acta (2011) 0.94
Early nasogastric tube feeding versus nil per os in mild to moderate acute pancreatitis: a randomized controlled trial. Clin Nutr (2012) 0.92
Overexpression of the gap junction protein Cx43 as found in diabetic foot ulcers can retard fibroblast migration. Cell Biol Int (2012) 0.91
The challenge for a European network of biobanks for rare diseases taken up by RD-Connect. Pathobiology (2015) 0.91
Connexin expression in homotypic and heterotypic cell coupling in the developing cerebral cortex. J Comp Neurol (2002) 0.91
The involvement of Ca2+ and integrins in directional responses of zebrafish keratocytes to electric fields. J Cell Physiol (2009) 0.90
The proteome of mesenteric lymph during acute pancreatitis and implications for treatment. JOP (2009) 0.90
Proteins associated with immunopurified granules from a model pancreatic islet beta-cell system: proteomic snapshot of an endocrine secretory granule. J Proteome Res (2009) 0.89
Ca(2+) signalling and gap junction coupling within and between pigment epithelium and neural retina in the developing chick. Eur J Neurosci (2004) 0.88
Molecular changes evoked by triethylenetetramine treatment in the extracellular matrix of the heart and aorta in diabetic rats. Mol Pharmacol (2006) 0.88
Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation. Cardiovasc Diabetol (2014) 0.88
Transient upregulation of connexin43 gap junctions and synchronized cell cycle control precede myoblast fusion in regenerating skeletal muscle in vivo. Histochem Cell Biol (2005) 0.87
Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice. Diabetes (2009) 0.87
Donor Hepatic Steatosis and Outcome After Liver Transplantation: a Systematic Review. J Gastrointest Surg (2015) 0.86
Reversal of diabetes-evoked changes in mitochondrial protein expression of cardiac left ventricle by treatment with a copper(II)-selective chelator. Proteomics Clin Appl (2007) 0.86
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells. J Mol Cell Biol (2013) 0.86
Importance of Connexin-43 based gap junction in cirrhosis and acute-on-chronic liver failure. J Hepatol (2013) 0.85
Gap junction protein expression and cellularity: comparison of immature and adult equine digital tendons. J Anat (2007) 0.85
Using a diagnostic tool to identify elevated protease activity levels in chronic and stalled wounds: a consensus panel discussion. Ostomy Wound Manage (2011) 0.85
Knockdown of connexin43-mediated regulation of the zone of polarizing activity in the developing chick limb leads to digit truncation. Dev Growth Differ (2002) 0.85
Immunohistochemical detection of connexin36 in sympathetic preganglionic and somatic motoneurons in the adult rat. Auton Neurosci (2008) 0.84
The impact of hepatic steatosis on hepatic ischemia-reperfusion injury in experimental studies: a systematic review. Biomed Res Int (2013) 0.84
Modulation of intracellular reactive oxygen species level in chondrocytes by IGF-1, FGF, and TGF-beta1. Connect Tissue Res (2007) 0.84
Lymph heart in chick--somitic origin, development and embryonic oedema. Development (2007) 0.83
Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment. Cardiovasc Diabetol (2013) 0.83
Patellofemoral complications after posterior-stabilized total knee arthroplasty: a comparison of 2 different implant designs. J Arthroplasty (2002) 0.83
Impact of ischaemic preconditioning on experimental steatotic livers following hepatic ischaemia-reperfusion injury: a systematic review. HPB (Oxford) (2014) 0.83
Gap-junction proteins in retinal development: new roles for the "nexus". Physiology (Bethesda) (2009) 0.83
Connexin dynamics in the privileged wound healing of the buccal mucosa. Wound Repair Regen (2013) 0.82
Talactoferrin alfa, a recombinant human lactoferrin promotes healing of diabetic neuropathic ulcers: a phase 1/2 clinical study. Am J Surg (2007) 0.82
Birds and longevity: does flight driven aerobicity provide an oxidative sink? Ageing Res Rev (2011) 0.82
Warming and humidification have no effect on oxidative stress during pneumoperitoneum in rats. Minim Invasive Ther Allied Technol (2011) 0.82
Antisense delivery and protein knockdown within the intact central nervous system. Front Biosci (2006) 0.82
Energy substrate metabolism of mouse cumulus-oocyte complexes: response to follicle-stimulating hormone is mediated by the phosphatidylinositol 3-kinase pathway and is associated with oocyte maturation. Biol Reprod (2004) 0.82
Connexins and diabetes. Cardiol Res Pract (2012) 0.81
The role of NGF uptake in selective vulnerability to cell death in ageing sympathetic neurons. Eur J Neurosci (2004) 0.81
A simple and rapid method for identifying and semi-quantifying peptide hormones in isolated pancreatic islets by direct-tissue matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom (2011) 0.81
Mice lacking the neuropeptide alpha-calcitonin gene-related peptide are protected against diet-induced obesity. Endocrinology (2010) 0.81
High quantity and variable quality of guidelines for acute pancreatitis: a systematic review. Am J Gastroenterol (2010) 0.81
Impaired ATP turnover and ADP supply depress cardiac mitochondrial respiration and elevate superoxide in nonfailing spontaneously hypertensive rat hearts. Am J Physiol Cell Physiol (2009) 0.81
Quantitative proteomic profiling identifies new renal targets of copper(II)-selective chelation in the reversal of diabetic nephropathy in rats. Proteomics (2009) 0.81
Protection of the heart by treatment with a divalent-copper-selective chelator reveals a novel mechanism underlying cardiomyopathy in diabetic rats. Cardiovasc Diabetol (2013) 0.81
Acute pancreatitis severity is exacerbated by intestinal ischemia-reperfusion conditioned mesenteric lymph. Surgery (2007) 0.80
The use of connexin-based therapeutic approaches to target inflammatory diseases. Methods Mol Biol (2013) 0.80
The potential role for xanthine oxidase inhibition in major intra-abdominal surgery. World J Surg (2008) 0.80
Myoblast proliferation and syncytial fusion both depend on connexin43 function in transfected skeletal muscle primary cultures. Exp Cell Res (2007) 0.80
In vitro optimization of antisense oligodeoxynucleotide design: an example using the connexin gene family. J Biomol Tech (2006) 0.79
Evidence that alpha-calcitonin gene-related peptide is a neurohormone that controls systemic lipid availability and utilization. Endocrinology (2007) 0.78
Impaired insulin secretion in perfused pancreases isolated from offspring of female rats fed a low protein whey-based diet. JOP (2008) 0.78
Illuminating the molecular basis of diabetic arteriopathy: a proteomic comparison of aortic tissue from diabetic and healthy rats. Proteomics (2010) 0.78
Integration of scaffolds into full-thickness skin wounds: the connexin response. Adv Healthc Mater (2013) 0.78
In differentiating prefusion myoblasts connexin43 gap junction coupling is upregulated before myoblast alignment then reduced in post-mitotic cells. Histochem Cell Biol (2005) 0.77
A comprehensive classification of invasive procedures for treating the local complications of acute pancreatitis based on visualization, route, and purpose. Pancreatology (2011) 0.77
Factors affecting patient adherence to recommended measures for prevention of recurrent venous ulcers. J Wound Ostomy Continence Nurs (2013) 0.77
Early organ-specific mitochondrial dysfunction of jejunum and lung found in rats with experimental acute pancreatitis. HPB (Oxford) (2011) 0.77
Multiphoton imaging of chick retinal development in relation to gap junctional communication. J Physiol (2007) 0.76
Levels of gap junction proteins in coronary arterioles and aorta of hamsters exposed to the cold and during hibernation and arousal. J Histochem Cytochem (2004) 0.76
Leptin Is Associated With Persistence of Hyperglycemia in Acute Pancreatitis: A Prospective Clinical Study. Medicine (Baltimore) (2016) 0.76
Probing the urinary proteome of severe acute pancreatitis. HPB (Oxford) (2007) 0.76
Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex i makes the liver susceptible to prolonged cold ischemia. Liver Transpl (2015) 0.75
Indicators of replicative damage in equine tendon fibroblast monolayers. BMC Vet Res (2013) 0.75
Hepatic mitochondrial function analysis using needle liver biopsy samples. PLoS One (2013) 0.75