PubRank

Wolf Reik

Author PubWeight™ 215.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Evolution and functions of long noncoding RNAs. Cell 2009 17.54
2 Active genes dynamically colocalize to shared sites of ongoing transcription. Nat Genet 2004 9.57
3 Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 2011 9.33
4 Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010 8.84
5 Epigenetic reprogramming in mammals. Hum Mol Genet 2005 6.73
6 Epigenetic reprogramming in mouse primordial germ cells. Mech Dev 2002 6.67
7 CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A 2006 5.95
8 Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 2002 5.86
9 5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nat Commun 2011 5.66
10 Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops. Nat Genet 2004 5.47
11 Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis 2003 5.19
12 Epigenetic reprogramming in plant and animal development. Science 2010 5.18
13 Quantitative sequencing of 5-methylcytosine and 5-hydroxymethylcytosine at single-base resolution. Science 2012 5.17
14 Placental-specific IGF-II is a major modulator of placental and fetal growth. Nature 2002 5.10
15 Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 2004 4.86
16 The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell 2012 4.32
17 Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet 2011 4.25
18 Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet 2003 4.25
19 Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet 2008 3.89
20 DNA demethylation by DNA repair. Trends Genet 2009 3.49
21 Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation. Nat Genet 2004 3.47
22 Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet 2009 3.25
23 BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol 2012 3.24
24 Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal. Nat Rev Mol Cell Biol 2009 3.12
25 FGF signaling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency. Cell Stem Cell 2013 2.79
26 Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol 2008 2.77
27 The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat Cell Biol 2012 2.73
28 NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature 2013 2.63
29 Molecular subtypes and phenotypic expression of Beckwith-Wiedemann syndrome. Eur J Hum Genet 2005 2.62
30 Dynamic chromatin modifications characterise the first cell cycle in mouse embryos. Dev Biol 2005 2.51
31 Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians. Nat Genet 2008 2.20
32 Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos. Curr Biol 2003 2.14
33 Resourceful imprinting. Nature 2004 2.10
34 Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol 2012 1.94
35 Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems. Proc Natl Acad Sci U S A 2005 1.90
36 An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype. Hum Mol Genet 2003 1.85
37 Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions. Hum Mol Genet 2003 1.73
38 Methylome analysis using MeDIP-seq with low DNA concentrations. Nat Protoc 2012 1.70
39 Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers. Philos Trans R Soc Lond B Biol Sci 2013 1.70
40 The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing. Development 2009 1.69
41 Placental overgrowth in mice lacking the imprinted gene Ipl. Proc Natl Acad Sci U S A 2002 1.67
42 Germline mutation in NLRP2 (NALP2) in a familial imprinting disorder (Beckwith-Wiedemann Syndrome). PLoS Genet 2009 1.64
43 Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development 2012 1.55
44 Mice deficient in APOBEC2 and APOBEC3. Mol Cell Biol 2005 1.55
45 Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nat Protoc 2013 1.54
46 A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biol 2013 1.50
47 Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer. Semin Cell Dev Biol 2003 1.44
48 Dnmt2-dependent methylomes lack defined DNA methylation patterns. Proc Natl Acad Sci U S A 2013 1.43
49 Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo. Development 2006 1.38
50 Structural differences in centromeric heterochromatin are spatially reconciled on fertilisation in the mouse zygote. Chromosoma 2007 1.33
51 Conceptual links between DNA methylation reprogramming in the early embryo and primordial germ cells. Curr Opin Cell Biol 2013 1.25
52 Evidence that paternal expression of the epsilon-sarcoglycan gene accounts for reduced penetrance in myoclonus-dystonia. Am J Hum Genet 2002 1.24
53 Clinical and molecular genetic features of Beckwith-Wiedemann syndrome associated with assisted reproductive technologies. Hum Reprod 2008 1.23
54 Direct sequencing of small genomes on the Pacific Biosciences RS without library preparation. Biotechniques 2012 1.18
55 Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans. BMC Genet 2005 1.14
56 Frequent RASSF1A tumour suppressor gene promoter methylation in Wilms' tumour and colorectal cancer. Oncogene 2002 1.10
57 Active demethylation in mouse zygotes involves cytosine deamination and base excision repair. Epigenetics Chromatin 2013 1.06
58 The two-domain hypothesis in Beckwith-Wiedemann syndrome: autonomous imprinting of the telomeric domain of the distal chromosome 7 cluster. Hum Mol Genet 2005 1.02
59 Pairing of homologous regions in the mouse genome is associated with transcription but not imprinting status. PLoS One 2012 1.01
60 Non-coding transcripts in the H19 imprinting control region mediate gene silencing in transgenic Drosophila. EMBO Rep 2007 1.00
61 Disruption of mesodermal enhancers for Igf2 in the minute mutant. Development 2002 1.00
62 Incomplete methylation reprogramming in SCNT embryos. Nat Genet 2012 0.97
63 Evaluation of epigenetic marks in human embryos derived from IVF and ICSI. Hum Reprod 2010 0.97
64 Genomic imprinting controls matrix attachment regions in the Igf2 gene. Mol Cell Biol 2003 0.96
65 Developmental adaptations to increased fetal nutrient demand in mouse genetic models of Igf2-mediated overgrowth. FASEB J 2011 0.95
66 A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA. Mamm Genome 2007 0.95
67 DNA demethylases: a new epigenetic frontier in drug discovery. Drug Discov Today 2011 0.94
68 Shifting behaviour: epigenetic reprogramming in eusocial insects. Curr Opin Cell Biol 2012 0.93
69 Raised late pregnancy glucose concentrations in mice carrying pups with targeted disruption of H19delta13. Diabetes 2009 0.92
70 Tandem repeat hypothesis in imprinting: deletion of a conserved direct repeat element upstream of H19 has no effect on imprinting in the Igf2-H19 region. Mol Cell Biol 2004 0.92
71 Safeguarding parental identity: Dnmt1 maintains imprints during epigenetic reprogramming in early embryogenesis. Genes Dev 2008 0.92
72 Developmental biology: the X-inactivation yo-yo. Nature 2005 0.87
73 Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA. Hum Mol Genet 2003 0.86
74 Robust 3D DNA FISH using directly labeled probes. J Vis Exp 2013 0.84
75 Replication timing properties within the mouse distal chromosome 7 imprinting cluster. Biosci Biotechnol Biochem 2002 0.83
76 Regulation of lineage specific DNA hypomethylation in mouse trophectoderm. PLoS One 2013 0.81
77 Retrotransposons and germ cells: reproduction, death, and diversity. F1000 Biol Rep 2010 0.81
78 Reprogramming by cell fusion: boosted by Tets. Mol Cell 2013 0.80
79 The need for Eed. Nat Genet 2003 0.80
80 Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells. Mol Cell 2016 0.78
81 Artificial sperm and epigenetic reprogramming. Nat Biotechnol 2006 0.78
82 Etoposide induces nuclear re-localisation of AID. PLoS One 2013 0.77
83 Increased placental glucose transport rates in pregnant mice carrying fetuses with targeted disruption of their placental-specific Igf2 transcripts are not associated with raised circulating glucose concentrations. Exp Diabetes Res 2011 0.75
84 The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy. J Clin Invest 2016 0.75
85 Wolf Reik: Inheritance beyond DNA. Interview by Nicole Lebrasseur. J Cell Biol 2010 0.75
86 Gene expression: Silent clones speak up. Nature 2003 0.75
87 Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human. Cell 2015 0.75