Published in Nature on February 10, 2013
TET enzymes, TDG and the dynamics of DNA demethylation. Nature (2013) 3.49
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription. Nat Rev Mol Cell Biol (2013) 3.18
Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell (2014) 3.17
Mechanisms and models of somatic cell reprogramming. Nat Rev Genet (2013) 2.09
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming. Cell Stem Cell (2013) 1.91
Predicting the human epigenome from DNA motifs. Nat Methods (2014) 1.88
Chromatin dynamics during cellular reprogramming. Nature (2013) 1.79
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C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells. Nature (2013) 1.57
Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming. Cell Stem Cell (2015) 1.53
Vitamin C modulates TET1 function during somatic cell reprogramming. Nat Genet (2013) 1.45
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Breathing-in epigenetic change with vitamin C. EMBO Rep (2013) 1.29
Global DNA methylation remodeling accompanies CD8 T cell effector function. J Immunol (2013) 1.27
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol (2013) 1.27
MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner. Cell Stem Cell (2014) 1.25
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Potential functional roles of DNA demethylation intermediates. Trends Biochem Sci (2013) 1.21
A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal. EMBO J (2013) 1.16
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Genome-wide alteration of 5-hydroxymethylcytosine in a mouse model of fragile X-associated tremor/ataxia syndrome. Hum Mol Genet (2013) 1.03
Concise review: pursuing self-renewal and pluripotency with the stem cell factor Nanog. Stem Cells (2013) 1.00
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Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a. Biochem Biophys Res Commun (2013) 0.95
A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. Mol Cell (2014) 0.94
The role of pluripotency gene regulatory network components in mediating transitions between pluripotent cell states. Curr Opin Genet Dev (2013) 0.93
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A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells. Mol Syst Biol (2013) 0.89
Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation. Mol Cell Biol (2015) 0.88
Roles for Tbx3 in regulation of two-cell state and telomere elongation in mouse ES cells. Sci Rep (2013) 0.88
Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions. Epigenetics (2013) 0.88
The extended pluripotency protein interactome and its links to reprogramming. Curr Opin Genet Dev (2014) 0.86
Insights into Chemoresistance of Prostate Cancer. Int J Biol Sci (2015) 0.86
Collaborative rewiring of the pluripotency network by chromatin and signalling modulating pathways. Nat Commun (2015) 0.86
TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues. Nucleic Acids Res (2015) 0.85
Alterations of 5-hydroxymethylcytosine in human cancers. Cancers (Basel) (2013) 0.85
Chemical approaches to cell reprogramming. Curr Opin Genet Dev (2014) 0.85
Pluripotency transcription factor Oct4 mediates stepwise nucleosome demethylation and depletion. Mol Cell Biol (2015) 0.85
Induction of pluripotency by defined factors. Proc Jpn Acad Ser B Phys Biol Sci (2014) 0.84
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Effects of Tet-mediated oxidation products of 5-methylcytosine on DNA transcription in vitro and in mammalian cells. Sci Rep (2014) 0.83
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Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming. Stem Cell Reports (2014) 0.82
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Cytosine modifications in neurodevelopment and diseases. Cell Mol Life Sci (2013) 0.81
Epigenetic mechanisms of tumorigenicity manifesting in stem cells. Oncogene (2014) 0.81
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First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia. Haematologica (2013) 0.80
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The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells. Genes Dev (2016) 0.79
Nanog, Oct4 and Tet1 interplay in establishing pluripotency. Sci Rep (2016) 0.79
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Reactivation of Х chromosome upon reprogramming leads to changes in the replication pattern and 5hmC accumulation. Chromosoma (2013) 0.78
Zfp281 Coordinates Opposing Functions of Tet1 and Tet2 in Pluripotent States. Cell Stem Cell (2016) 0.78
Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naïve pluripotency by complementary mechanisms. Proc Natl Acad Sci U S A (2016) 0.78
Roles of small molecules in somatic cell reprogramming. Acta Pharmacol Sin (2013) 0.78
An HDAC2-TET1 switch at distinct chromatin regions significantly promotes the maturation of pre-iPS to iPS cells. Nucleic Acids Res (2015) 0.78
DNA methylation and hydroxymethylation in stem cells. Cell Biochem Funct (2015) 0.77
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Pluripotency factor Nanog is tumorigenic by deregulating DNA damage response in somatic cells. Oncogene (2015) 0.77
C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells. Exp Neurol (2015) 0.77
Epigenetics, vitamin supplements and cellular reprogramming. Nat Genet (2013) 0.77
Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901. Stem Cells Int (2015) 0.76
TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells. J Exp Clin Cancer Res (2016) 0.76
Secreted Ephrin Receptor A7 Promotes Somatic Cell Reprogramming by Inducing ERK Activity Reduction. Stem Cell Reports (2015) 0.76
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"TET-on" pluripotency. Cell Res (2013) 0.75
Snai1 represses Nanog to promote embryonic stem cell differentiation. Genom Data (2015) 0.75
The nexus of Tet1 and the pluripotency network. Cell Stem Cell (2013) 0.75
Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells. Stem Cells (2016) 0.75
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A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages. Nat Cell Biol (2013) 1.45