Published in Nat Cell Biol on August 01, 2003
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TRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damage. Mol Cell Biol (2014) 1.00
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Ubiquitylation of Cdk9 by Skp2 facilitates optimal Tat transactivation. J Virol (2005) 0.87
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Regulation of peroxisome proliferator-activated receptor-alpha by MDM2. Toxicol Sci (2008) 0.83
Identifying chemicals with potential therapy of HIV based on protein-protein and protein-chemical interaction network. PLoS One (2013) 0.82
HIV-1 Rev downregulates Tat expression and viral replication via modulation of NAD(P)H:quinine oxidoreductase 1 (NQO1). Nat Commun (2015) 0.81
Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases. J Biol Chem (2009) 0.80
Tat-induced histopathological alterations mediate hippocampus-associated behavioural impairments in rats. Behav Brain Funct (2015) 0.80
p53-derived host restriction of HIV-1 replication by protein kinase R-mediated Tat phosphorylation and inactivation. J Virol (2015) 0.80
A design principle underlying the paradoxical roles of E3 ubiquitin ligases. Sci Rep (2014) 0.79
The ubiquitin-conjugating system: multiple roles in viral replication and infection. Cells (2014) 0.79
Newly designed six-membered azasugar nucleotide-containing phosphorothioate oligonucleotides as potent human immunodeficiency virus type 1 inhibitors. Antimicrob Agents Chemother (2005) 0.78
Cullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signaling. Front Plant Sci (2015) 0.78
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation. Nat Commun (2016) 0.78
HIV-1 Vpr redirects host ubiquitination pathway. J Virol (2014) 0.77
The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7. J Biol Chem (2016) 0.76
Modulation of the stability and activities of HIV-1 Tat by its ubiquitination and carboxyl-terminal region. Cell Biosci (2014) 0.76
PJA2 ubiquitinates the HIV-1 Tat protein with atypical chain linkages to activate viral transcription. Sci Rep (2017) 0.75
Induced degradation of Tat by nucleocapsid (NC) via the proteasome pathway and its effect on HIV transcription. Viruses (2013) 0.75
Monsef Benkirane awarded 2013 Ming K. Jeang Foundation Retrovirology Prize: landmark HIV-1 research honoured. Retrovirology (2013) 0.75
Regulation of transcriptional activators by DNA-binding domain ubiquitination. Cell Death Differ (2017) 0.75
Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cells. Virol J (2010) 0.75
HIV-1 Tat Recruits HDM2 E3 Ligase To Target IRF-1 for Ubiquitination and Proteasomal Degradation. MBio (2016) 0.75
Immune regulator ABIN1 suppresses HIV-1 transcription by negatively regulating the ubiquitination of Tat. Retrovirology (2017) 0.75
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx. Nature (2011) 9.30
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature (2003) 6.11
Towards an HIV cure: a global scientific strategy. Nat Rev Immunol (2012) 5.52
Suppression of microRNA-silencing pathway by HIV-1 during virus replication. Science (2007) 5.07
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol (2002) 5.02
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation. Nat Rev Cancer (2007) 4.69
Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development. Proc Natl Acad Sci U S A (2007) 4.04
Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function. Cell (2004) 3.73
Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing. Immunity (2005) 3.70
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP. Mol Cell (2010) 3.49
Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65. J Biol Chem (2002) 3.48
Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J (2002) 3.42
Molecular mechanisms of cellular transformation by HTLV-1 Tax. Oncogene (2005) 2.96
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells. Retrovirology (2012) 2.92
Impact factor, H index, peer comparisons, and Retrovirology: is it time to individualize citation metrics? Retrovirology (2007) 2.87
The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation. Cell (2005) 2.85
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53. Proc Natl Acad Sci U S A (2003) 2.73
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein. Cell Host Microbe (2012) 2.66
Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1. Cell Rep (2013) 2.56
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation. Cell (2006) 2.50
A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. J Biol Chem (2009) 2.40
Suv39H1 and HP1gamma are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency. EMBO J (2007) 2.37
Transportin-SR2 imports HIV into the nucleus. Curr Biol (2008) 2.35
HIV-1 encoded candidate micro-RNAs and their cellular targets. Retrovirology (2004) 2.23
Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies. Cell (2012) 2.18
SAMHD1 is mutated recurrently in chronic lymphocytic leukemia and is involved in response to DNA damage. Blood (2013) 2.18
The chaperone-associated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation. J Biol Chem (2005) 2.01
Heterozygous deletion of mitotic arrest-deficient protein 1 (MAD1) increases the incidence of tumors in mice. Cancer Res (2007) 1.96
MicroRNA profile changes in human immunodeficiency virus type 1 (HIV-1) seropositive individuals. Retrovirology (2008) 1.96
Changes in microRNA expression profiles in HIV-1-transfected human cells. Retrovirology (2005) 1.95
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency. J Clin Invest (2003) 1.92
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J (2006) 1.87
Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac. Retrovirology (2012) 1.87
Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation. EMBO J (2008) 1.87
Human cellular restriction factors that target HIV-1 replication. BMC Med (2009) 1.86
Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation. EMBO J (2002) 1.81
Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. Nature (2002) 1.80
siRNA targeting of the viral E6 oncogene efficiently kills human papillomavirus-positive cancer cells. Oncogene (2003) 1.78
Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2. Nat Cell Biol (2007) 1.70
Pyrosequencing of small non-coding RNAs in HIV-1 infected cells: evidence for the processing of a viral-cellular double-stranded RNA hybrid. Nucleic Acids Res (2009) 1.69
The roles of microRNAs in mammalian virus infection. Biochim Biophys Acta (2008) 1.64
Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1. Cancer Res (2008) 1.63
Viral and cellular RNA helicases as antiviral targets. Nat Rev Drug Discov (2005) 1.59
Role of the histone acetyl transferase Tip60 in the p53 pathway. J Biol Chem (2004) 1.56
The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms. Mol Cell (2007) 1.56
Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin. Proc Natl Acad Sci U S A (2011) 1.56
NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression. MBio (2013) 1.55
Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII. Cell (2012) 1.49
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. Mol Cell (2012) 1.44
Suppression of HIV-1 replication by microRNA effectors. Retrovirology (2009) 1.44
Involvement of the DNA repair protein hHR23 in p53 degradation. Mol Cell Biol (2003) 1.38
HIV-1 TAR RNA subverts RNA interference in transfected cells through sequestration of TAR RNA-binding protein, TRBP. J Biol Chem (2006) 1.35
Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein. Mol Cell Biol (2002) 1.34
RISCy business: MicroRNAs, pathogenesis, and viruses. J Biol Chem (2007) 1.32
Transcriptional and post-transcriptional regulation of HIV-1 gene expression: role of cellular factors for Tat and Rev. Future Microbiol (2006) 1.32
Histone acetyltransferase hALP and nuclear membrane protein hsSUN1 function in de-condensation of mitotic chromosomes. J Biol Chem (2007) 1.31
Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein. Mol Cell Biol (2006) 1.31
Requirement for Sun1 in the expression of meiotic reproductive genes and piRNA. Development (2009) 1.30
A capsid-encoded PPxY-motif facilitates adenovirus entry. PLoS Pathog (2010) 1.29
FAT10 plays a role in the regulation of chromosomal stability. J Biol Chem (2006) 1.28
Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF. EMBO J (2002) 1.27
Interferon-induced exonuclease ISG20 exhibits an antiviral activity against human immunodeficiency virus type 1. J Gen Virol (2005) 1.27
Human T-lymphotropic virus type I tax activates I-kappa B kinase by inhibiting I-kappa B kinase-associated serine/threonine protein phosphatase 2A. J Biol Chem (2002) 1.25
HTLV-1 Tax and adult T-cell leukemia. Front Biosci (2007) 1.25
UBE1L2, a novel E1 enzyme specific for ubiquitin. J Biol Chem (2007) 1.25
Abnormal centrosome amplification in cells through the targeting of Ran-binding protein-1 by the human T cell leukemia virus type-1 Tax oncoprotein. Proc Natl Acad Sci U S A (2005) 1.24
MicroRNAs and human retroviruses. Biochim Biophys Acta (2011) 1.23
The role of the ubiquitin ligase E6-AP in human papillomavirus E6-mediated degradation of PDZ domain-containing proteins. J Biol Chem (2006) 1.23
Prevalent loss of mitotic spindle checkpoint in adult T-cell leukemia confers resistance to microtubule inhibitors. J Biol Chem (2001) 1.23
The LINC complex is essential for hearing. J Clin Invest (2013) 1.22
Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity. J Virol (2004) 1.22
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling. J Virol (2011) 1.21
H-index, mentoring-index, highly-cited and highly-accessed: how to evaluate scientists? Retrovirology (2008) 1.20
HIV-1 Tat interaction with Dicer: requirement for RNA. Retrovirology (2006) 1.20
Tat and trans-activation-responsive (TAR) RNA-independent induction of HIV-1 long terminal repeat by human and murine cyclin T1 requires Sp1. J Biol Chem (2002) 1.19