Published in Mol Biol Evol on July 28, 2003
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The scale of mutational variation in the murid genome. Genome Res (2005) 1.95
Reduced X-linked diversity in derived populations of house mice. Genetics (2007) 1.70
Characteristics, causes and evolutionary consequences of male-biased mutation. Proc Biol Sci (2007) 1.57
Human-macaque comparisons illuminate variation in neutral substitution rates. Genome Biol (2008) 1.41
Genome-wide survey for biologically functional pseudogenes. PLoS Comput Biol (2006) 1.38
X chromosomes and autosomes evolve at similar rates in Drosophila: no evidence for faster-X protein evolution. Genome Res (2006) 1.31
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CpG dinucleotides and the mutation rate of non-CpG DNA. Genome Res (2008) 1.19
Genomic regionality in rates of evolution is not explained by clustering of genes of comparable expression profile. Genome Res (2004) 1.14
A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome. Genome Res (2006) 1.06
Insertions and deletions are male biased too: a whole-genome analysis in rodents. Genome Res (2004) 1.05
Recombination, dominance and selection on amino acid polymorphism in the Drosophila genome: contrasting patterns on the X and fourth chromosomes. Genetics (2003) 1.04
Hypermutation of the inactive X chromosome is a frequent event in cancer. Cell (2013) 0.96
Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution rates. Genome Biol Evol (2009) 0.88
Male-driven evolution in closely related species of the mouse genus Mus. J Mol Evol (2005) 0.88
Substitution rate heterogeneity and the male mutation bias. J Mol Evol (2006) 0.87
Measuring the prevalence of regional mutation rates: an analysis of silent substitutions in mammals, fungi, and insects. BMC Evol Biol (2008) 0.84
Evaluating the relationship between spermatogenic silencing of the X chromosome and evolution of the Y chromosome in chimpanzee and human. PLoS One (2010) 0.83
The genetics of sex chromosomes: evolution and implications for hybrid incompatibility. Ann N Y Acad Sci (2012) 0.82
Late replicating domains are highly recombining in females but have low male recombination rates: implications for isochore evolution. PLoS One (2011) 0.78
Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics. BMC Evol Biol (2006) 0.76
Organizational heterogeneity of vertebrate genomes. PLoS One (2012) 0.76
Male Mutation Bias Is the Main Force Shaping Chromosomal Substitution Rates in Monotreme Mammals. Genome Biol Evol (2017) 0.75
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science (2005) 5.55
Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science (2005) 4.79
Geometric cues for directing the differentiation of mesenchymal stem cells. Proc Natl Acad Sci U S A (2010) 4.63
Accelerated evolution of nervous system genes in the origin of Homo sapiens. Cell (2004) 4.24
Testing the neutral theory of molecular evolution with genomic data from Drosophila. Nature (2002) 3.51
Human lineage-specific amplification, selection, and neuronal expression of DUF1220 domains. Science (2006) 2.18
Systematic comparison of constitutive promoters and the doxycycline-inducible promoter. PLoS One (2010) 2.08
Positive selection on the human genome. Hum Mol Genet (2004) 1.95
Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity. Nat Genet (2004) 1.71
Nestin is required for the proper self-renewal of neural stem cells. Stem Cells (2010) 1.62
Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans. Hum Mol Genet (2004) 1.61
Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage. Proc Natl Acad Sci U S A (2006) 1.54
Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size. Hum Mol Genet (2004) 1.46
How mammalian sex chromosomes acquired their peculiar gene content. Bioessays (2004) 1.45
Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells. Mol Cell Biochem (2007) 1.39
Genetic links between brain development and brain evolution. Nat Rev Genet (2005) 1.33
Selective constraint on noncoding regions of hominid genomes. PLoS Comput Biol (2005) 1.32
Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ. Gene (2006) 1.29
The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. Hum Mol Genet (2003) 1.24
Genetic basis of human brain evolution. Trends Neurosci (2008) 1.22
The structures of coiled-coil domains from type III secretion system translocators reveal homology to pore-forming toxins. J Mol Biol (2012) 1.20
Protecting against wayward human induced pluripotent stem cells with a suicide gene. Biomaterials (2012) 1.20
The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. Hum Mol Genet (2007) 1.16
Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming. Mol Cell (2012) 1.14
Proteomic identification of differently expressed proteins responsible for osteoblast differentiation from human mesenchymal stem cells. Mol Cell Biochem (2007) 1.13
A highly unexpected strong correlation between fixation probability of nonsynonymous mutations and mutation rate. Trends Genet (2005) 1.13
FunnyBase: a systems level functional annotation of Fundulus ESTs for the analysis of gene expression. BMC Genomics (2004) 1.12
A genome-wide screen for noncoding elements important in primate evolution. BMC Evol Biol (2008) 1.12
Adaptive evolution of MRG, a neuron-specific gene family implicated in nociception. Genome Res (2003) 1.10
Evolutionary history and genome organization of DUF1220 protein domains. G3 (Bethesda) (2012) 1.08
Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides. J Mol Biol (2006) 1.07
Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. Nat Genet (2005) 1.06
Molecular evolution of functional genes on the mammalian Y chromosome. Mol Biol Evol (2002) 1.06
Robust signals of coevolution of interacting residues in mammalian proteomes identified by phylogeny-aided structural analysis. Nat Genet (2005) 1.05
A universal evolutionary index for amino acid changes. Mol Biol Evol (2004) 1.03
PPARγ suppression inhibits adipogenesis but does not promote osteogenesis of human mesenchymal stem cells. Int J Biochem Cell Biol (2011) 0.99
CrossSearch, a user-friendly search engine for detecting chemically cross-linked peptides in conjugated proteins. Mol Cell Proteomics (2008) 0.96
Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate. Gene (2005) 0.96
Systematically assessing the influence of 3-dimensional structural context on the molecular evolution of mammalian proteomes. Mol Biol Evol (2006) 0.96
Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway. J Bacteriol (2013) 0.94
Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell. Neuroreport (2006) 0.94
Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. FEBS Lett (2006) 0.92
Expression of nestin in lymph node metastasis and lymphangiogenesis in non-small cell lung cancer patients. Hum Pathol (2010) 0.92
A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway. Hum Mol Genet (2006) 0.90
Diverse fates of paralogs following segmental duplication of telomeric genes. Genomics (2004) 0.88
Systematic identification of cis-silenced genes by trans complementation. Hum Mol Genet (2008) 0.88
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. Cancer Res (2012) 0.88
SPEED: a molecular-evolution-based database of mammalian orthologous groups. Bioinformatics (2006) 0.87
Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells. Differentiation (2008) 0.87
Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells. Biomaterials (2012) 0.87
A genetic legacy from archaic Homo. Trends Genet (2007) 0.87
Evidence for a critical role of gene occlusion in cell fate restriction. Cell Res (2011) 0.85
Generation of functional hepatocytes from mouse induced pluripotent stem cells. J Cell Physiol (2010) 0.85
Chromatin analysis of occluded genes. Hum Mol Genet (2009) 0.84
Virtual polymorphism: finding divergent peptide matches in mass spectrometry data. Anal Chem (2007) 0.84
Uncovering the mutation-fixation correlation in short lineages. BMC Evol Biol (2007) 0.84
Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates. Hum Mol Genet (2006) 0.83
The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun (2009) 0.83
Effects of chromosomal rearrangements on human-chimpanzee molecular evolution. Genomics (2004) 0.82
The evolution of word composition in metazoan promoter sequence. PLoS Comput Biol (2006) 0.81
The X chromosome: not just her brother's keeper. Nat Genet (2005) 0.81
A stem cell-based tool for small molecule screening in adipogenesis. PLoS One (2010) 0.80
Extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host. Hum Mol Genet (2007) 0.80
ChemVassa: A New Method for Identifying Small Molecule Hits in Drug Discovery. Open Med Chem J (2012) 0.79
Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells. Genome Res (2013) 0.79
Slower cycling of nestin-positive cells in neurosphere culture. Neuroreport (2006) 0.79
Hereditary hyperekplexia caused by novel mutations of GLRA1 in Turkish families. Mol Diagn (2004) 0.79
Assessment of embryotoxicity of compounds in cosmetics by the embryonic stem cell test. Toxicol Mech Methods (2010) 0.78
Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene. Biotechniques (2006) 0.78
What makes us human: revisiting an age-old question in the genomic era. J Biomed Discov Collab (2006) 0.77
Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro. BMC Cell Biol (2010) 0.77
Different classes of tissue-specific genes show different levels of noncoding conservation. Genomics (2005) 0.77
Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells. Cell Biol Int (2008) 0.77
Mathematical models for the proliferation of neural stem/progenitor cells in clonogenic culture. Rejuvenation Res (2007) 0.76
Efficient genetic modification of cynomolgus monkey embryonic stem cells with lentiviral vectors. Cell Transplant (2010) 0.76
Involvement of extracellular factors in maintaining self-renewal of neural stem cell by nestin. Neuroreport (2014) 0.76
Establishment and characterization of two new human embryonic stem cell lines, SYSU-1 and SYSU-2. Chin Med J (Engl) (2007) 0.75
Detection of selection utilizing molecular phylogenetics: a possible approach. Genetica (2011) 0.75
Multiple independent origins of sex chromosomes in amniotes. Proc Natl Acad Sci U S A (2006) 0.75
Isolation, characterization and gene modification of fetal neural stem/progenitor cells from cynomolgus monkey. Neuroreport (2008) 0.75
Examining Trichophyton tonsurans genotype and biochemical phenotype as determinants of disease severity in tinea capitis. Med Mycol (2008) 0.75