Published in Hum Mol Genet on September 15, 2006
The evolution of mammalian gene families. PLoS One (2006) 3.04
A natural history of the human mind: tracing evolutionary changes in brain and cognition. J Anat (2008) 1.35
Genetic causes of microcephaly and lessons for neuronal development. Wiley Interdiscip Rev Dev Biol (2012) 1.34
Genesis of a fungal non-self recognition repertoire. PLoS One (2007) 1.17
In search of a unifying theory of complex brain evolution. Ann N Y Acad Sci (2009) 1.12
Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes. Genome Res (2007) 0.92
Transcriptome-wide expansion of non-coding regulatory switches: evidence from co-occurrence of Alu exonization, antisense and editing. Nucleic Acids Res (2013) 0.84
Human cells display reduced apoptotic function relative to chimpanzee cells. PLoS One (2012) 0.80
Phylogenetic Analysis Supports a Link between DUF1220 Domain Number and Primate Brain Expansion. Genome Biol Evol (2015) 0.78
Genetic correlates of the evolving primate brain. Prog Brain Res (2012) 0.76
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science (2005) 5.55
Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science (2005) 4.79
Geometric cues for directing the differentiation of mesenchymal stem cells. Proc Natl Acad Sci U S A (2010) 4.63
Accelerated evolution of nervous system genes in the origin of Homo sapiens. Cell (2004) 4.24
Systematic comparison of constitutive promoters and the doxycycline-inducible promoter. PLoS One (2010) 2.08
Positive selection on the human genome. Hum Mol Genet (2004) 1.95
Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity. Nat Genet (2004) 1.71
Nestin is required for the proper self-renewal of neural stem cells. Stem Cells (2010) 1.62
Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans. Hum Mol Genet (2004) 1.61
Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage. Proc Natl Acad Sci U S A (2006) 1.54
Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size. Hum Mol Genet (2004) 1.46
How mammalian sex chromosomes acquired their peculiar gene content. Bioessays (2004) 1.45
Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells. Mol Cell Biochem (2007) 1.39
Genetic links between brain development and brain evolution. Nat Rev Genet (2005) 1.33
Selective constraint on noncoding regions of hominid genomes. PLoS Comput Biol (2005) 1.32
Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ. Gene (2006) 1.29
The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. Hum Mol Genet (2003) 1.24
Genetic basis of human brain evolution. Trends Neurosci (2008) 1.22
Protecting against wayward human induced pluripotent stem cells with a suicide gene. Biomaterials (2012) 1.20
Genic mutation rates in mammals: local similarity, chromosomal heterogeneity, and X-versus-autosome disparity. Mol Biol Evol (2003) 1.19
The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. Hum Mol Genet (2007) 1.16
Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming. Mol Cell (2012) 1.14
A highly unexpected strong correlation between fixation probability of nonsynonymous mutations and mutation rate. Trends Genet (2005) 1.13
Proteomic identification of differently expressed proteins responsible for osteoblast differentiation from human mesenchymal stem cells. Mol Cell Biochem (2007) 1.13
A genome-wide screen for noncoding elements important in primate evolution. BMC Evol Biol (2008) 1.12
Adaptive evolution of MRG, a neuron-specific gene family implicated in nociception. Genome Res (2003) 1.10
Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. Nat Genet (2005) 1.06
Robust signals of coevolution of interacting residues in mammalian proteomes identified by phylogeny-aided structural analysis. Nat Genet (2005) 1.05
PPARγ suppression inhibits adipogenesis but does not promote osteogenesis of human mesenchymal stem cells. Int J Biochem Cell Biol (2011) 0.99
Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate. Gene (2005) 0.96
Systematically assessing the influence of 3-dimensional structural context on the molecular evolution of mammalian proteomes. Mol Biol Evol (2006) 0.96
Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell. Neuroreport (2006) 0.94
Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. FEBS Lett (2006) 0.92
Expression of nestin in lymph node metastasis and lymphangiogenesis in non-small cell lung cancer patients. Hum Pathol (2010) 0.92
Diverse fates of paralogs following segmental duplication of telomeric genes. Genomics (2004) 0.88
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. Cancer Res (2012) 0.88
Systematic identification of cis-silenced genes by trans complementation. Hum Mol Genet (2008) 0.88
SPEED: a molecular-evolution-based database of mammalian orthologous groups. Bioinformatics (2006) 0.87
Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells. Differentiation (2008) 0.87
A genetic legacy from archaic Homo. Trends Genet (2007) 0.87
Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells. Biomaterials (2012) 0.87
Evidence for a critical role of gene occlusion in cell fate restriction. Cell Res (2011) 0.85
Generation of functional hepatocytes from mouse induced pluripotent stem cells. J Cell Physiol (2010) 0.85
Uncovering the mutation-fixation correlation in short lineages. BMC Evol Biol (2007) 0.84
Chromatin analysis of occluded genes. Hum Mol Genet (2009) 0.84
Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates. Hum Mol Genet (2006) 0.83
The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun (2009) 0.83
Effects of chromosomal rearrangements on human-chimpanzee molecular evolution. Genomics (2004) 0.82
The evolution of word composition in metazoan promoter sequence. PLoS Comput Biol (2006) 0.81
The X chromosome: not just her brother's keeper. Nat Genet (2005) 0.81
Extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host. Hum Mol Genet (2007) 0.80
A stem cell-based tool for small molecule screening in adipogenesis. PLoS One (2010) 0.80
Slower cycling of nestin-positive cells in neurosphere culture. Neuroreport (2006) 0.79
Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells. Genome Res (2013) 0.79
Hereditary hyperekplexia caused by novel mutations of GLRA1 in Turkish families. Mol Diagn (2004) 0.79
Assessment of embryotoxicity of compounds in cosmetics by the embryonic stem cell test. Toxicol Mech Methods (2010) 0.78
Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene. Biotechniques (2006) 0.78
Different classes of tissue-specific genes show different levels of noncoding conservation. Genomics (2005) 0.77
Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells. Cell Biol Int (2008) 0.77
What makes us human: revisiting an age-old question in the genomic era. J Biomed Discov Collab (2006) 0.77
Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro. BMC Cell Biol (2010) 0.77
Mathematical models for the proliferation of neural stem/progenitor cells in clonogenic culture. Rejuvenation Res (2007) 0.76
Efficient genetic modification of cynomolgus monkey embryonic stem cells with lentiviral vectors. Cell Transplant (2010) 0.76
Involvement of extracellular factors in maintaining self-renewal of neural stem cell by nestin. Neuroreport (2014) 0.76
Multiple independent origins of sex chromosomes in amniotes. Proc Natl Acad Sci U S A (2006) 0.75
Establishment and characterization of two new human embryonic stem cell lines, SYSU-1 and SYSU-2. Chin Med J (Engl) (2007) 0.75
Isolation, characterization and gene modification of fetal neural stem/progenitor cells from cynomolgus monkey. Neuroreport (2008) 0.75