Published in Gene on March 14, 2006
Primary microcephaly: do all roads lead to Rome? Trends Genet (2009) 3.60
Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development (2010) 2.31
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A primary microcephaly protein complex forms a ring around parental centrioles. Nat Genet (2011) 1.80
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Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamics. Mol Biol Cell (2009) 1.16
Codon-based tests of positive selection, branch lengths, and the evolution of mammalian immune system genes. Immunogenetics (2008) 1.15
Two distinct regions of Mto1 are required for normal microtubule nucleation and efficient association with the gamma-tubulin complex in vivo. J Cell Sci (2008) 1.12
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Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome. PLoS Genet (2012) 1.06
Previously described sequence variant in CDK5RAP2 gene in a Pakistani family with autosomal recessive primary microcephaly. BMC Med Genet (2007) 1.01
Genetics and biology of microcephaly and lissencephaly. Semin Pediatr Neurol (2009) 1.00
Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development. Am J Hum Genet (2008) 0.93
Comparative evolutionary analysis of the FoxG1 transcription factor from diverse vertebrates identifies conserved recognition sites for microRNA regulation. Dev Genes Evol (2007) 0.92
Dimerization of CPAP orchestrates centrosome cohesion plasticity. J Biol Chem (2009) 0.89
Genetic regulation of human brain development: lessons from Mendelian diseases. Ann N Y Acad Sci (2010) 0.86
A fast-evolving human NPAS3 enhancer gained reporter expression in the developing forebrain of transgenic mice. Philos Trans R Soc Lond B Biol Sci (2013) 0.84
Phylogeny and adaptive evolution of the brain-development gene microcephalin (MCPH1) in cetaceans. BMC Evol Biol (2011) 0.82
Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and the origin of humans. BMC Biol (2013) 0.80
ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size. PLoS Genet (2016) 0.80
Chromosomal Rearrangements as Barriers to Genetic Homogenization between Archaic and Modern Humans. Mol Biol Evol (2015) 0.79
Microcephaly genes evolved adaptively throughout the evolution of eutherian mammals. BMC Evol Biol (2014) 0.78
Molecular evolution of WDR62, a gene that regulates neocorticogenesis. Meta Gene (2016) 0.77
Genetic correlates of the evolving primate brain. Prog Brain Res (2012) 0.76
Microcephaly genes and risk of late-onset Alzheimer disease. Alzheimer Dis Assoc Disord (2011) 0.75
A Novel Deletion Mutation in ASPM Gene in an Iranian Family with Autosomal Recessive Primary Microcephaly. Iran J Child Neurol (2013) 0.75
Phenotypical manifestations of partial trisomy 9 and monosomy 4 in two siblings. Neurol Sci (2008) 0.75
Regional selection of the brain size regulating gene CASC5 provides new insight into human brain evolution. Hum Genet (2016) 0.75
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol (2010) 9.01
Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science (2005) 5.55
Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science (2005) 4.79
Geometric cues for directing the differentiation of mesenchymal stem cells. Proc Natl Acad Sci U S A (2010) 4.63
Accelerated evolution of nervous system genes in the origin of Homo sapiens. Cell (2004) 4.24
Systematic comparison of constitutive promoters and the doxycycline-inducible promoter. PLoS One (2010) 2.08
Positive selection on the human genome. Hum Mol Genet (2004) 1.95
Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies. Hum Mol Genet (2008) 1.73
Rate of molecular evolution of the seminal protein gene SEMG2 correlates with levels of female promiscuity. Nat Genet (2004) 1.71
Nestin is required for the proper self-renewal of neural stem cells. Stem Cells (2010) 1.62
Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans. Hum Mol Genet (2004) 1.61
Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro. J Pharmacol Exp Ther (2007) 1.57
Evidence that the adaptive allele of the brain size gene microcephalin introgressed into Homo sapiens from an archaic Homo lineage. Proc Natl Acad Sci U S A (2006) 1.54
Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size. Hum Mol Genet (2004) 1.46
How mammalian sex chromosomes acquired their peculiar gene content. Bioessays (2004) 1.45
Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells. Mol Cell Biochem (2007) 1.39
Genetic links between brain development and brain evolution. Nat Rev Genet (2005) 1.33
Selective constraint on noncoding regions of hominid genomes. PLoS Comput Biol (2005) 1.32
The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. Hum Mol Genet (2003) 1.24
Genetic basis of human brain evolution. Trends Neurosci (2008) 1.22
Protecting against wayward human induced pluripotent stem cells with a suicide gene. Biomaterials (2012) 1.20
Genic mutation rates in mammals: local similarity, chromosomal heterogeneity, and X-versus-autosome disparity. Mol Biol Evol (2003) 1.19
The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. Hum Mol Genet (2007) 1.16
Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming. Mol Cell (2012) 1.14
A highly unexpected strong correlation between fixation probability of nonsynonymous mutations and mutation rate. Trends Genet (2005) 1.13
Proteomic identification of differently expressed proteins responsible for osteoblast differentiation from human mesenchymal stem cells. Mol Cell Biochem (2007) 1.13
A genome-wide screen for noncoding elements important in primate evolution. BMC Evol Biol (2008) 1.12
Adaptive evolution of MRG, a neuron-specific gene family implicated in nociception. Genome Res (2003) 1.10
Functional characterization of the human TPH2 5' regulatory region: untranslated region and polymorphisms modulate gene expression in vitro. Hum Genet (2007) 1.08
Trak1 mutation disrupts GABA(A) receptor homeostasis in hypertonic mice. Nat Genet (2005) 1.06
Robust signals of coevolution of interacting residues in mammalian proteomes identified by phylogeny-aided structural analysis. Nat Genet (2005) 1.05
Trace amine associated receptor 1 signaling in activated lymphocytes. J Neuroimmune Pharmacol (2011) 1.05
Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice. J Neurosci Res (2010) 1.03
Augmentation of methamphetamine-induced behaviors in transgenic mice lacking the trace amine-associated receptor 1. Pharmacol Biochem Behav (2011) 1.01
PPARγ suppression inhibits adipogenesis but does not promote osteogenesis of human mesenchymal stem cells. Int J Biochem Cell Biol (2011) 0.99
Refinement of primate copy number variation hotspots identifies candidate genomic regions evolving under positive selection. Genome Biol (2011) 0.99
Human polymorphism and human-chimpanzee divergence in pseudoautosomal region correlate with local recombination rate. Gene (2005) 0.96
Systematically assessing the influence of 3-dimensional structural context on the molecular evolution of mammalian proteomes. Mol Biol Evol (2006) 0.96
The resurgence and genetic implications of New World primates in biomedical research. Trends Genet (2012) 0.95
Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell. Neuroreport (2006) 0.94
Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing. FEBS Lett (2006) 0.92
Expression of nestin in lymph node metastasis and lymphangiogenesis in non-small cell lung cancer patients. Hum Pathol (2010) 0.92
Quantitative molecular assessment of chimerism across tissues in marmosets and tamarins. BMC Genomics (2012) 0.90
A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway. Hum Mol Genet (2006) 0.90
Development and validation of a SNP-based assay for inferring the genetic ancestry of rhesus macaques (Macaca mulatta). Am J Primatol (2014) 0.90
Nonhuman primate models in the genomic era: a paradigm shift. ILAR J (2013) 0.89
Cloning, expression, and functional analysis of rhesus monkey trace amine-associated receptor 6: evidence for lack of monoaminergic association. J Neurosci Res (2008) 0.89
Diverse fates of paralogs following segmental duplication of telomeric genes. Genomics (2004) 0.88
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma. Cancer Res (2012) 0.88
The XVth World Congress of Psychiatric Genetics, October 7-11, 2007: Rapporteur summaries of oral presentations. Am J Med Genet B Neuropsychiatr Genet (2008) 0.88
Systematic identification of cis-silenced genes by trans complementation. Hum Mol Genet (2008) 0.88
The effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: a retrospective analysis. Horm Behav (2009) 0.88
Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells. Differentiation (2008) 0.87
SPEED: a molecular-evolution-based database of mammalian orthologous groups. Bioinformatics (2006) 0.87
A genetic legacy from archaic Homo. Trends Genet (2007) 0.87
Suicide gene-mediated ablation of tumor-initiating mouse pluripotent stem cells. Biomaterials (2012) 0.87
Evidence for a critical role of gene occlusion in cell fate restriction. Cell Res (2011) 0.85
Generation of functional hepatocytes from mouse induced pluripotent stem cells. J Cell Physiol (2010) 0.85
Uncovering the mutation-fixation correlation in short lineages. BMC Evol Biol (2007) 0.84
Large-scale polymorphism discovery in macaque G-protein coupled receptors. BMC Genomics (2013) 0.84
Trace amine associated receptor 1 modulates behavioral effects of ethanol. Subst Abuse (2013) 0.84
Chromatin analysis of occluded genes. Hum Mol Genet (2009) 0.84
Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates. Hum Mol Genet (2006) 0.83
The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun (2009) 0.83
Effects of chromosomal rearrangements on human-chimpanzee molecular evolution. Genomics (2004) 0.82
The X chromosome: not just her brother's keeper. Nat Genet (2005) 0.81
The evolution of word composition in metazoan promoter sequence. PLoS Comput Biol (2006) 0.81
Extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host. Hum Mol Genet (2007) 0.80
A stem cell-based tool for small molecule screening in adipogenesis. PLoS One (2010) 0.80
Slower cycling of nestin-positive cells in neurosphere culture. Neuroreport (2006) 0.79
Resource brief: the National Non-Human Primate DNA Bank. Methods (2009) 0.79
Systematic mapping of occluded genes by cell fusion reveals prevalence and stability of cis-mediated silencing in somatic cells. Genome Res (2013) 0.79
Hereditary hyperekplexia caused by novel mutations of GLRA1 in Turkish families. Mol Diagn (2004) 0.79
Assessment of embryotoxicity of compounds in cosmetics by the embryonic stem cell test. Toxicol Mech Methods (2010) 0.78
Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene. Biotechniques (2006) 0.78
Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro. BMC Cell Biol (2010) 0.77
Different classes of tissue-specific genes show different levels of noncoding conservation. Genomics (2005) 0.77
What makes us human: revisiting an age-old question in the genomic era. J Biomed Discov Collab (2006) 0.77
Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells. Cell Biol Int (2008) 0.77
Growth-associated protein-43 and ephrin B3 induction in the brain of adult SIV-infected rhesus macaques. J Neurovirol (2011) 0.77
Mathematical models for the proliferation of neural stem/progenitor cells in clonogenic culture. Rejuvenation Res (2007) 0.76