Published in Proc Natl Acad Sci U S A on August 12, 2003
Interferon induced IFIT family genes in host antiviral defense. Int J Biol Sci (2013) 1.13
Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesis. Fibrogenesis Tissue Repair (2010) 1.09
Polymorphisms in bovine immune genes and their associations with somatic cell count and milk production in dairy cattle. BMC Genet (2010) 0.98
Coevolution and life cycle specialization of plant cell wall degrading enzymes in a hemibiotrophic pathogen. Mol Biol Evol (2013) 0.97
Differences in distribution of single nucleotide polymorphisms among intracellular pattern recognition receptors in pigs. Immunogenetics (2008) 0.97
Recognition events and host-pathogen co-evolution in gene-for-gene resistance to flax rust. Funct Plant Biol (2009) 0.93
Diversity and evolution of 11 innate immune genes in Bos taurus taurus and Bos taurus indicus cattle. Proc Natl Acad Sci U S A (2009) 0.93
Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance. BMC Evol Biol (2008) 0.90
Association of toll-like receptor four single nucleotide polymorphisms with incidence of infectious bovine keratoconjunctivitis (IBK) in cattle. Immunogenetics (2010) 0.84
Detecting the effects of selection at the population level in six bovine immune genes. BMC Genet (2008) 0.84
Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection. PLoS One (2011) 0.83
Genotypic analysis of Asp299Gly and Thr399Ile polymorphism of Toll-like receptor 4 in systemic autoimmune diseases of Korean population. Rheumatol Int (2007) 0.82
Protein evolution of Toll-like receptors 4, 5 and 7 within Galloanserae birds. Genet Sel Evol (2014) 0.81
Risk haplotype analysis for bovine paratuberculosis. Mamm Genome (2009) 0.78
How immunogenetically different are domestic pigs from wild boars: a perspective from single-nucleotide polymorphisms of 19 immunity-related candidate genes. Immunogenetics (2013) 0.76
Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis). BMC Genet (2014) 0.76
Nucleotide Sequencing and SNP Detection of Toll-Like Receptor-4 Gene in Murrah Buffalo (Bubalus bubalis). ISRN Mol Biol (2012) 0.75
Toll-like receptors (TLRs) and mannan-binding lectin (MBL): on constant alert in a hostile environment. Ups J Med Sci (2011) 0.75
PAML: a program package for phylogenetic analysis by maximum likelihood. Comput Appl Biosci (1997) 45.07
MEGA2: molecular evolutionary genetics analysis software. Bioinformatics (2001) 38.50
Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol Biol Evol (1986) 36.06
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity (1999) 17.40
Inference of haplotypes from PCR-amplified samples of diploid populations. Mol Biol Evol (1990) 16.18
Codon-substitution models for heterogeneous selection pressure at amino acid sites. Genetics (2000) 14.84
Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms. Am J Hum Genet (2001) 10.48
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med (1999) 9.23
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet (2000) 8.79
Variation is the spice of life. Nat Genet (2001) 7.62
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem (1999) 7.38
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol (2000) 6.57
Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med (2002) 5.70
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J Clin Invest (2000) 4.60
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection. Proc Natl Acad Sci U S A (2003) 4.56
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science (2002) 4.45
Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene. J Immunol (1980) 3.31
Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation. Proc Natl Acad Sci U S A (2000) 3.03
Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus). Genetics (1997) 2.65
Efficient selective screening of haplotype tag SNPs. Bioinformatics (2003) 2.57
Positive Darwinian selection promotes charge profile diversity in the antigen-binding cleft of class I major-histocompatibility-complex molecules. Mol Biol Evol (1990) 2.41
Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol (2002) 2.17
Construction and characterization of a bovine bacterial artificial chromosome library. Genomics (1995) 1.79
TOLL-like receptors linking innate and adaptive immune response. Vet Immunol Immunopathol (2003) 1.70
Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease. Immunol Rev (2002) 1.65
Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans. Genetics (2001) 1.49
Immunological reactions caused by infection with Mycobacterium paratuberculosis. A review. Nord Vet Med (1978) 1.42
Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4). Genome Biol (2000) 1.35
Regulatory roles for CD14 and phosphatidylinositol in the signaling via toll-like receptor 4-MD-2. Biochem Biophys Res Commun (2000) 1.18
MHCII, Tlr4 and Nramp1 genes control host pulmonary resistance against the opportunistic bacterium Pasteurella pneumotropica. J Leukoc Biol (2001) 1.04
Estimation of DNA sequence diversity in bovine cytokine genes. Mamm Genome (2001) 0.97
Pathogenesis of Mycobacterium bovis infection. Prog Vet Microbiol Immunol (1986) 0.93
Re-sequencing of DNA from a diverse panel of cattle reveals a high level of polymorphism in both intron and exon. Mamm Genome (1999) 0.82
Comparative fine maps of bovine toll-like receptor 4 and toll-like receptor 2 regions. Mamm Genome (2003) 0.82
The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23
Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds. Science (2009) 7.64
Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science (2005) 5.47
Whole genome linkage disequilibrium maps in cattle. BMC Genet (2007) 3.28
A high-resolution whole-genome cattle-human comparative map reveals details of mammalian chromosome evolution. Proc Natl Acad Sci U S A (2005) 2.62
High-resolution haplotype block structure in the cattle genome. BMC Genet (2009) 2.35
Association of a lysine-232/alanine polymorphism in a bovine gene encoding acyl-CoA:diacylglycerol acyltransferase (DGAT1) with variation at a quantitative trait locus for milk fat content. Proc Natl Acad Sci U S A (2002) 2.01
A cattle-human comparative map built with cattle BAC-ends and human genome sequence. Genome Res (2003) 1.92
Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia. Epigenetics (2012) 1.80
Real-time PCR assay for measurement of mouse telomeres. Comp Med (2006) 1.80
A physical map of the bovine genome. Genome Biol (2007) 1.56
An assessment of population structure in eight breeds of cattle using a whole genome SNP panel. BMC Genet (2008) 1.51
A 1463 gene cattle-human comparative map with anchor points defined by human genome sequence coordinates. Genome Res (2004) 1.48
Positional cloning of the gene LIMBIN responsible for bovine chondrodysplastic dwarfism. Proc Natl Acad Sci U S A (2002) 1.42
High resolution radiation hybrid maps of bovine chromosomes 19 and 29: comparison with the bovine genome sequence assembly. BMC Genomics (2007) 1.37
Discovery of novel epigenetic markers in non-Hodgkin's lymphoma. Carcinogenesis (2006) 1.23
DNA hypermethylation accompanied by transcriptional repression in follicular lymphoma. Genes Chromosomes Cancer (2009) 1.16
The first-generation whole-genome radiation hybrid map in the horse identifies conserved segments in human and mouse genomes. Genome Res (2003) 1.15
A high-resolution radiation hybrid map of rhesus macaque chromosome 5 identifies rearrangements in the genome assembly. Genomics (2008) 1.09
A first generation whole genome RH map of the river buffalo with comparison to domestic cattle. BMC Genomics (2008) 1.08
Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing. PLoS One (2010) 1.06
A gene-based high-resolution comparative radiation hybrid map as a framework for genome sequence assembly of a bovine chromosome 6 region associated with QTL for growth, body composition, and milk performance traits. BMC Genomics (2006) 1.03
Large-scale analysis of DNA methylation in chronic lymphocytic leukemia. Epigenomics (2009) 1.02
Exceptional conservation of horse-human gene order on X chromosome revealed by high-resolution radiation hybrid mapping. Proc Natl Acad Sci U S A (2004) 1.00
Construction of a 5000(rad) whole-genome radiation hybrid panel in the horse and generation of a comprehensive and comparative map for ECA11. Mamm Genome (2002) 0.96
Evidence that bovine forebrain embryonic zinc finger-like gene influences immune response associated with mastitis resistance. Proc Natl Acad Sci U S A (2006) 0.95
Conservation of gene order between horse and human X chromosomes as evidenced through radiation hybrid mapping. Genomics (2002) 0.94
Identification of endometrial genes regulated by early pregnancy, progesterone, and interferon tau in the ovine uterus. Biol Reprod (2005) 0.94
A detailed physical map of the horse Y chromosome. Proc Natl Acad Sci U S A (2004) 0.94
Diversity and evolution of 11 innate immune genes in Bos taurus taurus and Bos taurus indicus cattle. Proc Natl Acad Sci U S A (2009) 0.93
Wide-cross whole-genome radiation hybrid mapping of cotton (Gossypium hirsutum L.). Genetics (2004) 0.92
Wide-cross whole-genome radiation hybrid mapping of the cotton (Gossypium barbadense L.) genome. Mol Genet Genomics (2005) 0.92
A comparative radiation hybrid map of bovine chromosome 18 and homologous chromosomes in human and mice. Proc Natl Acad Sci U S A (2002) 0.91
A radiation hybrid map of bovine X chromosome (BTAX). Mamm Genome (2002) 0.89
Water buffalo genome science comes of age. Int J Biol Sci (2010) 0.89
A high resolution RH map of the bovine major histocompatibility complex. BMC Genomics (2009) 0.89
Comparative PRNP genotyping of U.S. cattle sires for potential association with BSE. Mamm Genome (2004) 0.89
Targeted construction of a high-resolution, integrated, comprehensive, and comparative map for a region specific to bovine chromosome 6 based on radiation hybrid mapping. Genomics (2002) 0.89
A high-resolution physical map of equine homologs of HSA19 shows divergent evolution compared with other mammals. Mamm Genome (2005) 0.88
Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma. J Virol (2004) 0.88
Glycogen branching enzyme (GBE1) mutation causing equine glycogen storage disease IV. Mamm Genome (2004) 0.86
Molecular detection of B-cell neoplasms by specific DNA methylation biomarkers. Int J Clin Exp Pathol (2010) 0.86
Application of disease-associated differentially expressed genes--mining for functional candidate genes for mastitis resistance in cattle. Genet Sel Evol (2003) 0.85
Hypermethylation of the DLC1 CpG island does not alter gene expression in canine lymphoma. BMC Genet (2009) 0.84
Evolution of the bovine TLR gene family and member associations with Mycobacterium avium subspecies paratuberculosis infection. PLoS One (2011) 0.83
High-resolution comparative mapping between human chromosomes 4 and 8 and bovine chromosome 27 provides genes and segments serving as positional candidates for udder health in cattle. Genomics (2004) 0.83
Effects of a single nucleotide polymorphism in the chicken NK-lysin gene on antimicrobial activity and cytotoxicity of cancer cells. Proc Natl Acad Sci U S A (2012) 0.83
Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK). J Biol Chem (2013) 0.82
Comparative fine maps of bovine toll-like receptor 4 and toll-like receptor 2 regions. Mamm Genome (2003) 0.82
Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia. Epigenomics (2010) 0.82
Multiclonal pattern of Jaagsiekte sheep retrovirus integration sites in ovine pulmonary adenocarcinoma. Virus Res (2005) 0.81
Relational analysis of CpG islands methylation and gene expression in human lymphomas using possibilistic C-means clustering and modified cluster fuzzy density. IEEE/ACM Trans Comput Biol Bioinform (2007) 0.81
Identification of genetic variation and putative regulatory regions in bovine CARD15. Mamm Genome (2006) 0.80
A line of Berlin Druckrey IV rats proposed as a new model for human hereditary ataxia. In Vivo (2002) 0.80
The bovine 5' AMPK gene family: mapping and single nucleotide polymorphism detection. Mamm Genome (2003) 0.80
Genome-wide DNA methylation analysis in precursor B-cells. Epigenetics (2014) 0.79
A 1.4-Mb interval RH map of horse chromosome 17 provides detailed comparison with human and mouse homologues. Genomics (2004) 0.79
Sequence analysis and polymorphism discovery in 4 members of the bovine cathelicidin gene family. J Hered (2009) 0.78
Molecular characterization of the Rocky Mountain elk (Cervus elaphus nelsoni) PRNP putative promoter. J Hered (2007) 0.78
The telomeric region of BTA18 containing a potential QTL region for health in cattle exhibits high similarity to the HSA19q region in humans. Genomics (2003) 0.78
Identification of a major locus interacting with MC1R and modifying black coat color in an F₂ Nellore-Angus population. Genet Sel Evol (2014) 0.78
Isolation of precursor B-cell subsets from umbilical cord blood. J Vis Exp (2013) 0.78
High-resolution RH map of horse chromosome 22 reveals a putative ancestral vertebrate chromosome. Genomics (2005) 0.77
Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia. Epigenetics (2015) 0.77
Chicken NK-lysin is an alpha-helical cationic peptide that exerts its antibacterial activity through damage of bacterial cell membranes. Poult Sci (2014) 0.77
Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity. Oncogene (2003) 0.76
An update of the goat genome assembly using dense radiation hybrid maps allows detailed analysis of evolutionary rearrangements in Bovidae. BMC Genomics (2014) 0.76
Steroid hormones acutely regulate expression of a Nudix protein-encoding gene in the endometrial epithelium of sheep. Mol Reprod Dev (2006) 0.76
Gene expression and DNA methylation status of chicken primordial germ cells. Mol Biotechnol (2013) 0.76
Radiation hybrid mapping and comparative sequence analysis of bovine RIG-I and MAVS genes. DNA Seq (2006) 0.76
Developmental exposure of fetal ovaries and fetal germ cells to endometriosis in an endometriosis model causes differential gene expression in the preimplantation embryos of the first-generation and second-generation embryos. Fertil Steril (2013) 0.75
A radiation hybrid map of bovine chromosome 27. Anim Genet (2002) 0.75
Genomic comparison of Lewis and Wistar-Furth rat substrains by use of microsatellite markers. J Am Assoc Lab Anim Sci (2007) 0.75
Materials composed of the Drosophila melanogaster protein ultrabithorax are cytocompatible. J Biomed Mater Res A (2013) 0.75
Identification and chromosome assignment of 23 genes expressed in meat and dairy cattle. Chromosome Res (2002) 0.75