The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases.

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Published in Biochem J on May 01, 1992

Authors

G Murphy1, F Willenbrock, R V Ward, M I Cockett, D Eaton, A J Docherty

Author Affiliations

1: Strangeways Research Laboratory, Worts Causeway, Cambridge, U.K.

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