Published in J Immunol on July 01, 1992
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med (1995) 8.31
CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line. Proc Natl Acad Sci U S A (1994) 1.70
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase. Mol Cell Biol (1994) 1.67
Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proc Natl Acad Sci U S A (1993) 1.53
IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase. EMBO J (1995) 1.47
p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation. Proc Natl Acad Sci U S A (1995) 1.33
RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter. Mol Cell Biol (1995) 1.29
Effect of CD28 signal transduction on c-Rel in human peripheral blood T cells. Mol Cell Biol (1994) 1.13
The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras. J Exp Med (1994) 1.09
CD28: a signalling perspective. Biochem J (1996) 1.08
Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins. Proc Natl Acad Sci U S A (1994) 0.96
Itk negatively regulates induction of T cell proliferation by CD28 costimulation. J Exp Med (1997) 0.95
Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity. Immunology (1993) 0.89
Signalling through CD28 T-cell activation pathway involves an inositol phospholipid-specific phospholipase C activity. Biochem J (1993) 0.88
Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK. Biochem J (1998) 0.86
Binding of Amadori glucose-modified albumin by the monocytic cell line MonoMac 6 activates protein kinase C epsilon protein tyrosine kinases and the transcription factors AP-1 and NF-kappaB. Glycoconj J (2001) 0.81
Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding. Mol Cell Biol (1997) 0.80
Anti-CD28 antibody- and IL-4-induced human T cell proliferation is sensitive to rapamycin. Clin Exp Immunol (1993) 0.77
Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28. Biochem J (1997) 0.75
The minimal gene complement of Mycoplasma genitalium. Science (1995) 32.41
Evidence for lateral gene transfer between Archaea and bacteria from genome sequence of Thermotoga maritima. Nature (1999) 14.42
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. Proc Natl Acad Sci U S A (1988) 5.75
Separating population structure from population history: a cladistic analysis of the geographical distribution of mitochondrial DNA haplotypes in the tiger salamander, Ambystoma tigrinum. Genetics (1995) 4.05
A study of proteases and protease-inhibitor complexes in biological fluids. J Exp Med (1978) 3.92
Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A. J Exp Med (1986) 3.24
Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proc Natl Acad Sci U S A (1989) 2.87
The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex. Proc Natl Acad Sci U S A (1989) 2.80
Dendritic cells initiate a two-stage mechanism for T lymphocyte proliferation. J Exp Med (1983) 2.76
Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2. J Exp Med (1983) 2.61
Secretion of plasminogen activator by human polymorphonuclear leukocytes. Modulation by glucocorticoids and other effectors. J Exp Med (1977) 2.60
Dendritic cells induce T lymphocytes to release B cell-stimulating factors by an interleukin 2-dependent mechanism. J Exp Med (1983) 2.42
Isolation of reovirus-like agents from patients with Crohn's disease. Lancet (1977) 2.24
Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A. J Exp Med (1984) 2.24
Human T cell activation. III. Rapid induction of a phosphorylated 28 kD/32 kD disulfide-linked early activation antigen (EA 1) by 12-o-tetradecanoyl phorbol-13-acetate, mitogens, and antigens. J Exp Med (1986) 2.17
Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody. J Exp Med (1988) 2.05
Role of infection in chronic bronchitis. Am Rev Respir Dis (1976) 1.81
The interaction of immunodeficiency viruses with dendritic cells. Curr Top Microbiol Immunol (2003) 1.79
Modeling the dynamic characteristics of pneumatic muscle. Ann Biomed Eng (2003) 1.62
Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A. J Exp Med (1989) 1.60
Specific protease deficiency in polymorphonuclear leukocytes of Chédiak-Higashi syndrome and beige mice. J Exp Med (1978) 1.60
Purification of murine T cell growth factor. A lymphocyte mitogen with helper activity. J Exp Med (1981) 1.57
Dendritic cells and the replication of HIV-1. J Leukoc Biol (1996) 1.48
Anti-CD45 inhibition of human B cell proliferation depends on the nature of activation signals and the state of B cell activation. A study with anti-IgM and anti-CDw40 antibodies. J Immunol (1989) 1.45
Mercury in the hair of crematoria workers. Lancet (1998) 1.45
The influence of interview on decision making and selection of prospective veterinary undergraduate students. Vet Rec (2013) 1.41
Recombinant adenovirus is an efficient and non-perturbing genetic vector for human dendritic cells. Eur J Immunol (1999) 1.40
Mature dendritic cells respond to SDF-1, but not to several beta-chemokines. Immunobiology (1998) 1.40
Enteric virus isolation in different cell cultures. Bull World Health Organ (1965) 1.39
During HIV-1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion. Clin Exp Immunol (1992) 1.36
Killed subunit influenza vaccine in children. Pediatrics (1973) 1.32
Acquired resistance and granuloma formation in experimental visceral leishmaniasis. Differential T cell and lymphokine roles in initial versus established immunity. J Immunol (1992) 1.31
Rheumatoid arthritis after rubella. Arthritis Rheum (1968) 1.31
RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes. J Exp Med (1979) 1.30
Osseous manifestations of the congenital rubella syndrome. Am J Dis Child (1965) 1.30
Coxsackievirus B epidemic at a Boy's Summer Camp. Isolation of virus from swimming water. JAMA (1973) 1.27
Control of cyclic adenosine 3',5'-monophosphate levels by depolarizing agents in fungi. J Bacteriol (1979) 1.22
Antibacterial activity of gentamicin sulfate in tissue culture. Appl Microbiol (1970) 1.22
Intrauterine rubella infection following immunization with rubella vaccine. JAMA (1970) 1.22
Cytotoxic T cells both produce and respond to interleukin 2. J Exp Med (1984) 1.17
The effect of lemon, orange and bergamot essential oils and their components on the survival of Campylobacter jejuni, Escherichia coli O157, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus in vitro and in food systems. J Appl Microbiol (2006) 1.15
Human T lymphocytes express a protein-tyrosine kinase homologous to p56LSTRA. Biochim Biophys Acta (1986) 1.15
Isolation and characterization of a viral agent from intestinal tissue of patients with Crohn's disease and other intestinal disorders. Prog Med Virol (1975) 1.15
Acebutolol in hypertension--double-blind trial against placebo. Br J Clin Pharmacol (1978) 1.14
Purified influenza vaccine: clinical and serologic responses to varying doses and different routes of immunization. J Infect Dis (1970) 1.13
Tumor-promoting phorbol esters stimulate the phosphorylation of ribosomal protein S6 in quiescent Reuber H35 hepatoma cells. J Biol Chem (1984) 1.13
A noninvasive protocol for anterior temporal lobectomy. Neurology (1992) 1.10
Antiquity of clonal salamander lineages revealed by mitochondrial DNA. Nature (1992) 1.09
Mild hypertension: a clinical trial conducted in hospital general practice. Br Med J (1976) 1.05
Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase. J Immunol (1990) 1.05
Cytomegalovirus encephalitis in immunologically normal adults. Successful treatment with vidarabine. JAMA (1977) 1.04
Vidarabine therapy for severe herpesvirus infections. An unusual syndrome of chronic varicella and transient immunologic deficiency. JAMA (1976) 1.03
Complete analysis of the presenilin 1 gene in early onset Alzheimer's disease. Neuroreport (1996) 1.02
Purification and biophysical properties of rhinoviruses. Proc Soc Exp Biol Med (1966) 1.01
Serum and secretory antibodies in patients with chronic bronchitis. Arch Intern Med (1973) 0.99
Rubella vaccine program: its implications in obstetric practice. Am J Obstet Gynecol (1972) 0.98
An etiologic investigation of infantile diarrhea in Houston during 1962 and 1963. Am J Epidemiol (1966) 0.98
Association of the p56lck protein tyrosine kinase with the Fc gamma RIIIA/CD16 complex in human natural killer cells. Eur J Immunol (1993) 0.98
Modulation and mapping of a human plasminogen activator by cell fusion. Cell (1978) 0.98
Isolation, propagation and neutralization of rubella virus in cultures of rabbit cornea (SIRC) cells. Proc Soc Exp Biol Med (1966) 0.97
Purified influenza vaccine trial in a children's home. Pediatrics (1970) 0.97
3,5-Bis(trifluoromethyl)pyrazoles: a novel class of NFAT transcription factor regulator. J Med Chem (2000) 0.97
Rhinovirus infections in a student population: isolation of five new serotypes. Am J Epidemiol (1968) 0.96
Legionnaires' disease in Vermont, May to October 1977. JAMA (1978) 0.96
Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin-mediated angioedema. Br J Pharmacol (2007) 0.96
Identification of the human T-lymphocyte protein-tyrosine kinase by peptide-specific antibodies. Biochem Biophys Res Commun (1986) 0.96
Phosphatidylinositol 3-kinase activity is not essential for CD28 costimulatory activity in Jurkat T cells: studies with a selective inhibitor, wortmannin. Eur J Immunol (1995) 0.95
Studies of the effect of cyclosporine in psoriasis in vivo: combined effects on activated T lymphocytes and epidermal regenerative maturation. J Invest Dermatol (1992) 0.95
Presentation of SIVgag to monkey T cells using dendritic cells transfected with a recombinant adenovirus. Eur J Immunol (2000) 0.95
Human T cell activation. IV. T cell activation and proliferation via the early activation antigen EA 1. J Exp Med (1989) 0.95
Insulin- and phorbol ester-stimulated phosphorylation of ribosomal protein S6. J Biol Chem (1985) 0.95
IL-6 enhances the generation of cytolytic T lymphocytes in the allogeneic mixed leucocyte reaction. Clin Exp Immunol (1992) 0.94
Rotavirus antibodies in Crohn's disease and ulcerative colitis. Lancet (1977) 0.94
Thermostability of rubella hemagglutination-inhibiting antibody. Appl Microbiol (1969) 0.93
CD28 signal transduction: tyrosine phosphorylation and receptor association of phosphoinositide-3 kinase correlate with Ca(2+)-independent costimulatory activity. Eur J Immunol (1994) 0.93
Passive haemagglutination test for anti-rhinovirus antibodies. Nat New Biol (1971) 0.93
Antibodies to interleukin 2. Effects on immune responses in vitro and in vivo. J Exp Med (1984) 0.92
Blood flow and metabolism during isometric contractions in cat skeletal muscle. J Appl Physiol Respir Environ Exerc Physiol (1981) 0.92
Vaccinia pneumonia in mice. A light and electron microscopic and viral assay study. Am J Pathol (1966) 0.91
Viral prostatitis. J Urol (1970) 0.90
Evaluation of amplitude and frequency components of the surface EMG as an index of muscle fatigue. Ergonomics (1982) 0.90
Context of MUC1 epitope: immunogenicity. Oncol Rep (2007) 0.90
Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation. Leukemia (2002) 0.90
Myocardial material mechanics: characteristic variation of the circumferential and longitudinal systolic moduli in left ventricular dysfunction. J Biomech (1984) 0.89
Herpes simplex virus hepatitis in mice: an electron-microscopic study. Exp Mol Pathol (1968) 0.89
Muscle fiber recruitment and blood pressure response to isometric exercise. J Appl Physiol Respir Environ Exerc Physiol (1981) 0.89
The anti-biofilm activity of lemongrass (Cymbopogon flexuosus) and grapefruit (Citrus paradisi) essential oils against five strains of Staphylococcus aureus. J Appl Microbiol (2012) 0.88
Beta-[3H]funaltrexamine-labeled mu-opioid receptors: species variations in molecular mass and glycosylation by complex-type, N-linked oligosaccharides. Mol Pharmacol (1993) 0.88
Bactericidal antibodies to Hemophilus influenzae. Proc Soc Exp Biol Med (1971) 0.88
Generation of MUC1-stimulated mononuclear cells using optimized conditions. Scand J Immunol (2007) 0.87
Fatal hand-foot-and-mouth disease in an adult caused by Coxsackievirus 47. JAMA (1979) 0.87
Dendritic cells generated from blood monocytes of HIV-1 patients are not infected and act as competent antigen presenting cells eliciting potent T-cell responses. Immunol Lett (1999) 0.87