Published in Mol Pharmacol on September 21, 2004
Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome. Psychopharmacology (Berl) (2006) 1.11
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proc Natl Acad Sci U S A (2005) 1.08
Will chronic e-cigarette use cause lung disease? Am J Physiol Lung Cell Mol Physiol (2015) 0.87
The α4 nicotinic receptor promotes CD4+ T-cell proliferation and a helper T-cell immune response. Mol Pharmacol (2013) 0.85
Cholinergic activation of hematopoietic stem cells: role in tobacco-related disease? Vasc Med (2010) 0.81
Nicotinic acetylcholine receptor expression on B-lymphoblasts of healthy versus schizophrenic subjects stratified for smoking: [3H]-nicotine binding is decreased in schizophrenia and correlates with negative symptoms. J Neural Transm (Vienna) (2011) 0.76
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation. Nature (2008) 5.77
Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends Cogn Sci (2006) 4.66
Experimental and theoretical approaches to conscious processing. Neuron (2011) 4.28
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov (2009) 3.26
A prokaryotic proton-gated ion channel from the nicotinic acetylcholine receptor family. Nature (2006) 3.04
X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel. Nature (2011) 3.00
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J Neurosci (2003) 2.85
A neuronal network model linking subjective reports and objective physiological data during conscious perception. Proc Natl Acad Sci U S A (2003) 2.79
Hierarchical control of dopamine neuron-firing patterns by nicotinic receptors. Neuron (2006) 2.69
Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism. Biophys J (2005) 2.33
The diversity of subunit composition in nAChRs: evolutionary origins, physiologic and pharmacologic consequences. J Neurobiol (2002) 2.20
Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice. J Neurosci (2002) 2.05
Nicotine upregulates its own receptors through enhanced intracellular maturation. Neuron (2005) 1.89
One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue. Proc Natl Acad Sci U S A (2010) 1.81
Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites. Proc Natl Acad Sci U S A (2002) 1.78
The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology (Berl) (2006) 1.76
Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure (2012) 1.69
Molecular tuning of fast gating in pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A (2005) 1.58
A neuronal model of predictive coding accounting for the mismatch negativity. J Neurosci (2012) 1.48
Ongoing spontaneous activity controls access to consciousness: a neuronal model for inattentional blindness. PLoS Biol (2005) 1.47
Distinct contributions of nicotinic acetylcholine receptor subunit alpha4 and subunit alpha6 to the reinforcing effects of nicotine. Proc Natl Acad Sci U S A (2011) 1.44
Executive and social behaviors under nicotinic receptor regulation. Proc Natl Acad Sci U S A (2003) 1.44
Altered map of visual space in the superior colliculus of mice lacking early retinal waves. J Neurosci (2005) 1.38
Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation. Proc Natl Acad Sci U S A (2013) 1.32
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors. Proc Natl Acad Sci U S A (2006) 1.32
Experimentally based model of a complex between a snake toxin and the alpha 7 nicotinic receptor. Proc Natl Acad Sci U S A (2002) 1.32
Conformational selection or induced fit? 50 years of debate resolved. F1000 Biol Rep (2011) 1.31
Pore conformations and gating mechanism of a Cys-loop receptor. Proc Natl Acad Sci U S A (2005) 1.31
Myocardial ischemic postconditioning against ischemia-reperfusion is impaired in ob/ob mice. Am J Physiol Heart Circ Physiol (2008) 1.25
Nicotine and serotonin in immune regulation and inflammatory processes: a perspective. J Leukoc Biol (2006) 1.22
An H-bond between two residues from different loops of the acetylcholine binding site contributes to the activation mechanism of nicotinic receptors. EMBO J (2003) 1.19
Cardioprotective effect of morphine and a blocker of glycogen synthase kinase 3 beta, SB216763 [3-(2,4-dichlorophenyl)-4(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione], via inhibition of the mitochondrial permeability transition pore. J Pharmacol Exp Ther (2008) 1.19
Localization of [3H]nicotine, [3H]cytisine, [3H]epibatidine, and [125I]alpha-bungarotoxin binding sites in the brain of Macaca mulatta. J Comp Neurol (2003) 1.18
Monitoring protein interactions in the living cell through the fluorescence decays of the cyan fluorescent protein. Chemphyschem (2006) 1.18
Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J Neurosci (2002) 1.17
Nicotine activates immature "silent" connections in the developing hippocampus. Proc Natl Acad Sci U S A (2003) 1.17
An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine. J Biol Chem (2004) 1.15
A gating mechanism of pentameric ligand-gated ion channels. Proc Natl Acad Sci U S A (2013) 1.15
Intracellular complexes of the beta2 subunit of the nicotinic acetylcholine receptor in brain identified by proteomics. Proc Natl Acad Sci U S A (2007) 1.15
α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6ß4 and α6ß2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release. FASEB J (2010) 1.12
Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice. J Physiol (2006) 1.12
Prefrontal nicotinic receptors control novel social interaction between mice. FASEB J (2011) 1.11
Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice. J Neurosci (2004) 1.10
Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors. Proc Natl Acad Sci U S A (2010) 1.10
Interplay of beta2* nicotinic receptors and dopamine pathways in the control of spontaneous locomotion. Proc Natl Acad Sci U S A (2008) 1.08
Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors. Neuropharmacology (2006) 1.08
Long-term effects of chronic nicotine exposure on brain nicotinic receptors. Proc Natl Acad Sci U S A (2007) 1.08
KCNE1 constrains the voltage sensor of Kv7.1 K+ channels. PLoS One (2008) 1.08
Perinatal exposure to nicotine causes deficits associated with a loss of nicotinic receptor function. Proc Natl Acad Sci U S A (2005) 1.08
A carbon monoxide-releasing molecule (CORM-3) uncouples mitochondrial respiration and modulates the production of reactive oxygen species. Free Radic Biol Med (2011) 1.08
Concentration-dependent plasma protein binding of the novel dipeptidyl peptidase 4 inhibitor BI 1356 due to saturable binding to its target in plasma of mice, rats and humans. J Pharm Pharmacol (2009) 1.07
Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system. Prog Brain Res (2004) 1.05
The emergence of human consciousness: from fetal to neonatal life. Pediatr Res (2009) 1.04
Complex fluorescence of the cyan fluorescent protein: comparisons with the H148D variant and consequences for quantitative cell imaging. Biochemistry (2008) 1.04
Electron microscopic evidence for nucleation and growth of 3D acetylcholine receptor microcrystals in structured lipid-detergent matrices. Proc Natl Acad Sci U S A (2003) 1.03
Beta2-containing nicotinic receptors contribute to the organization of sleep and regulate putative micro-arousals in mice. J Neurosci (2004) 1.02
Nicotinic receptors regulate the survival of newborn neurons in the adult olfactory bulb. Proc Natl Acad Sci U S A (2004) 1.01
A chimera encoding the fusion of an acetylcholine-binding protein to an ion channel is stabilized in a state close to the desensitized form of ligand-gated ion channels. C R Biol (2005) 1.01
Nicotine enhances intracellular nicotinic receptor maturation: a novel mechanism of neural plasticity? J Physiol Paris (2006) 1.01
Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. Neuropsychopharmacology (2005) 1.00
An inactivation gate in the selectivity filter of KCNQ1 potassium channels. Biophys J (2007) 0.98
{alpha}7 nicotinic acetylcholine receptor regulates airway epithelium differentiation by controlling basal cell proliferation. Am J Pathol (2009) 0.97
Rapid cooling preserves the ischaemic myocardium against mitochondrial damage and left ventricular dysfunction. Cardiovasc Res (2009) 0.96
Live imaging of neural structure and function by fibred fluorescence microscopy. EMBO Rep (2006) 0.96
Analysis of the cellular expression pattern of beta-CGRP in alpha-CGRP-deficient mice. J Comp Neurol (2004) 0.96
Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain (2004) 0.96
Allosteric transitions of Torpedo acetylcholine receptor in lipids, detergent and amphipols: molecular interactions vs. physical constraints. FEBS Lett (2002) 0.96
Behavioral sequence analysis reveals a novel role for beta2* nicotinic receptors in exploration. PLoS Comput Biol (2008) 0.95
Expression of mutant Ets protein at the neuromuscular synapse causes alterations in morphology and gene expression. EMBO Rep (2002) 0.95
S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels. PLoS One (2008) 0.94
Nicotinic receptors regulate B lymphocyte activation and immune response. Eur J Pharmacol (2005) 0.93
Role of the permeability transition pore in cytochrome C release from mitochondria during ischemia-reperfusion in rat liver. Biochem Pharmacol (2004) 0.93
Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum. Psychopharmacology (Berl) (2006) 0.93
beta 2 nicotinic acetylcholine receptor subunit modulates protective responses to stress: A receptor basis for sleep-disordered breathing after nicotine exposure. Proc Natl Acad Sci U S A (2002) 0.92
A neurocomputational hypothesis for nicotine addiction. Proc Natl Acad Sci U S A (2006) 0.92
14-3-3 gamma associates with muscle specific kinase and regulates synaptic gene transcription at vertebrate neuromuscular synapse. Proc Natl Acad Sci U S A (2004) 0.92
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe. Eur J Biochem (2002) 0.91
Attention-deficit/hyperactivity disorder: a plausible mouse model? Acta Paediatr (2006) 0.91
Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. Psychopharmacology (Berl) (2011) 0.91
Mechanism of Cl- selection by a glutamate-gated chloride (GluCl) receptor revealed through mutations in the selectivity filter. J Biol Chem (2006) 0.90
Resveratrol protects against cold ischemia-warm reoxygenation-induced damages to mitochondria and cells in rat liver. Eur J Pharmacol (2005) 0.90
Functional nicotinic acetylcholine receptors are expressed in B lymphocyte-derived cell lines. Mol Pharmacol (2003) 0.89
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries. FASEB J (2002) 0.89
Effects of curcumin and curcumin derivatives on mitochondrial permeability transition pore. Free Radic Biol Med (2004) 0.89
A versatile system for the neuronal subtype specific expression of lentiviral vectors. FASEB J (2009) 0.89
Object memory in young and aged mice after sevoflurane anaesthesia. Neuroreport (2009) 0.88
Peripheral benzodiazepine receptor-induced myocardial protection is mediated by inhibition of mitochondrial membrane permeabilization. J Pharmacol Exp Ther (2007) 0.88
Effects of the proteasome inhibitor ritonavir on glioma growth in vitro and in vivo. Mol Cancer Ther (2004) 0.88
Molecular dissection of Cl--selective Cys-loop receptor points to components that are dispensable or essential for channel activity. J Biol Chem (2011) 0.87
A non-radioactive ligand-binding assay for detection of cyanobacterial anatoxins using Torpedo electrocyte membranes. Toxicon (2008) 0.86