Published in J Biotechnol on December 19, 2003
Acetyl-coenzyme A carboxylases: versatile targets for drug discovery. J Cell Biochem (2006) 1.77
Discovering the hidden secondary metabolome of Myxococcus xanthus: a study of intraspecific diversity. Appl Environ Microbiol (2008) 1.40
Variation in tropical reef symbiont metagenomes defined by secondary metabolism. PLoS One (2011) 1.24
Exploitative and hierarchical antagonism in a cooperative bacterium. PLoS Biol (2005) 1.21
The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation. Proc Natl Acad Sci U S A (2006) 1.15
Analysis of myxobacterial secondary metabolism goes molecular. J Ind Microbiol Biotechnol (2006) 1.15
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation. Biochem Pharmacol (2010) 1.03
Carbonate Precipitation through Microbial Activities in Natural Environment, and Their Potential in Biotechnology: A Review. Front Bioeng Biotechnol (2016) 0.96
In vitro efficacy of Myxococcus fulvus ANSM068 to biotransform aflatoxin B₁. Int J Mol Sci (2010) 0.95
Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus. Appl Environ Microbiol (2006) 0.95
Complete genome sequence of Haliangium ochraceum type strain (SMP-2). Stand Genomic Sci (2010) 0.94
Isolation, biology and chemistry of the disorazoles: new anti-cancer macrodiolides. Nat Prod Rep (2009) 0.93
Discovery of the autonomously replicating plasmid pMF1 from Myxococcus fulvus and development of a gene cloning system in Myxococcus xanthus. Appl Environ Microbiol (2008) 0.91
Improving conjugation efficacy of Sorangium cellulosum by the addition of dual selection antibiotics. J Ind Microbiol Biotechnol (2008) 0.87
Biogeography and phylogenetic diversity of a cluster of exclusively marine myxobacteria. ISME J (2011) 0.85
Mutation and a high-throughput screening method for improving the production of Epothilones of Sorangium. J Ind Microbiol Biotechnol (2007) 0.84
A novel cold-adapted lipase from Sorangium cellulosum strain So0157-2: gene cloning, expression, and enzymatic characterization. Int J Mol Sci (2011) 0.84
Heterologous expression of the oxytetracycline biosynthetic pathway in Myxococcus xanthus. Appl Environ Microbiol (2010) 0.84
Use of in situ solid-phase adsorption in microbial natural product fermentation development. J Ind Microbiol Biotechnol (2013) 0.83
Scrutinizing the scaffolds of marine biosynthetics from different source organisms: Gram-negative cultured bacterial products enter center stage. J Nat Prod (2014) 0.83
Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy. PLoS One (2012) 0.82
Unusual outer membrane lipid composition of the gram-negative, lipopolysaccharide-lacking myxobacterium Sorangium cellulosum So ce56. J Biol Chem (2011) 0.82
Diversity of epothilone producers among Sorangium strains in producer-positive soil habitats. Microb Biotechnol (2013) 0.78
Novel expression hosts for complex secondary metabolite megasynthetases: Production of myxochromide in the thermopilic isolate Corallococcus macrosporus GT-2. Microb Cell Fact (2009) 0.77
The phosphatomes of the multicellular myxobacteria Myxococcus xanthus and Sorangium cellulosum in comparison with other prokaryotic genomes. PLoS One (2010) 0.77
Antimalarial activity of the myxobacterial macrolide chlorotonil a. Antimicrob Agents Chemother (2014) 0.77
The myxocoumarins A and B from Stigmatella aurantiaca strain MYX-030. Beilstein J Org Chem (2013) 0.76
AmyM, a Novel Maltohexaose-Forming α-Amylase from Corallococcus sp. strain EGB. Appl Environ Microbiol (2015) 0.76
Identification of a Novel Antibiotic from Myxobacterium Stigmatella Eracta WXNXJ-B and Evaluation of its Antitumor Effects I n - vitro. Iran J Pharm Res (2014) 0.75
High-throughput screening and whole genome sequencing identifies an antimicrobially active inhibitor of Vibrio cholerae. BMC Microbiol (2014) 0.75
Selection and a 3-Year Field Trial of Sorangium cellulosum KYC 3262 Against Anthracnose in Hot Pepper. Plant Pathol J (2014) 0.75
The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Nucleic Acids Res (2016) 0.75
Isolation and characterisation of the epothilone gene cluster with flanks from high alkalotolerant strain Sorangium cellulosum (So0157-2). World J Microbiol Biotechnol (2017) 0.75
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
GeneTrail--advanced gene set enrichment analysis. Nucleic Acids Res (2007) 5.10
Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting. Nat Biotechnol (2012) 2.54
Complete genome sequence of the myxobacterium Sorangium cellulosum. Nat Biotechnol (2007) 2.43
Ear deformations give bats a physical mechanism for fast adaptation of ultrasonic beam patterns. Phys Rev Lett (2011) 2.22
Evolutionary implications of bacterial polyketide synthases. Mol Biol Evol (2005) 2.06
The sensitivity of polar ozone depletion to proposed geoengineering schemes. Science (2008) 2.05
The complete genome sequence of the algal symbiont Dinoroseobacter shibae: a hitchhiker's guide to life in the sea. ISME J (2009) 2.00
The impact of bacterial genomics on natural product research. Angew Chem Int Ed Engl (2005) 1.70
Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5. Chem Biol (2006) 1.56
Formation of novel secondary metabolites by bacterial multimodular assembly lines: deviations from textbook biosynthetic logic. Curr Opin Chem Biol (2005) 1.51
Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases. Chembiochem (2006) 1.46
Biosynthetic pathway of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines. J Bacteriol (2005) 1.43
Discovering the hidden secondary metabolome of Myxococcus xanthus: a study of intraspecific diversity. Appl Environ Microbiol (2008) 1.40
Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes. J Virol (2003) 1.39
Recent developments towards the heterologous expression of complex bacterial natural product biosynthetic pathways. Curr Opin Biotechnol (2005) 1.36
Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. Chembiochem (2004) 1.35
Production of the antifungal isochromanone ajudazols A and B in Chondromyces crocatus Cm c5: biosynthetic machinery and cytochrome P450 modifications. Angew Chem Int Ed Engl (2008) 1.32
The cyclase-associated protein CAP as regulator of cell polarity and cAMP signaling in Dictyostelium. Mol Biol Cell (2003) 1.30
Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse. Int J Cancer (2013) 1.27
Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene (2004) 1.27
Noseleaf furrows in a horseshoe bat act as resonance cavities shaping the biosonar beam. Phys Rev Lett (2006) 1.27
Deregulation of tumor angiogenesis and blockade of tumor growth in PPARbeta-deficient mice. EMBO J (2007) 1.24
Myxobacterial secondary metabolites: bioactivities and modes-of-action. Nat Prod Rep (2010) 1.23
The impact of genomics on the exploitation of the myxobacterial secondary metabolome. Nat Prod Rep (2009) 1.23
Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ). PLoS One (2011) 1.23
Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Blood (2003) 1.22
The biosynthetic potential of myxobacteria and their impact in drug discovery. Curr Opin Drug Discov Devel (2009) 1.22
Diversity and evolution of repABC type plasmids in Rhodobacterales. Environ Microbiol (2009) 1.21
Steroid biosynthesis in prokaryotes: identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)-oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca. Mol Microbiol (2003) 1.20
Bacteria of the Roseobacter clade show potential for secondary metabolite production. Microb Ecol (2007) 1.20
Genes and enzymes involved in caffeic acid biosynthesis in the actinomycete Saccharothrix espanaensis. J Bacteriol (2006) 1.19
Myxobacteria--'microbial factories' for the production of bioactive secondary metabolites. Mol Biosyst (2009) 1.19
Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering. Chem Biol (2005) 1.18
Comparative genomic analysis of fruiting body formation in Myxococcales. Mol Biol Evol (2010) 1.17
Recent advances in the heterologous expression of microbial natural product biosynthetic pathways. Nat Prod Rep (2013) 1.16
Biosynthesis of the off-flavor 2-methylisoborneol by the myxobacterium Nannocystis exedens. Angew Chem Int Ed Engl (2007) 1.16
Protein-protein interactions in multienzyme megasynthetases. Chembiochem (2008) 1.16
Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta. J Mol Biol (2007) 1.16
The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation. Proc Natl Acad Sci U S A (2006) 1.15
Analysis of myxobacterial secondary metabolism goes molecular. J Ind Microbiol Biotechnol (2006) 1.15
Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes. Chembiochem (2005) 1.15
Synthetic biotechnology to study and engineer ribosomal bottromycin biosynthesis. Chem Biol (2012) 1.14
Extrachromosomal, extraordinary and essential--the plasmids of the Roseobacter clade. Appl Microbiol Biotechnol (2013) 1.13
Molecular structure of the rod domain of dictyostelium filamin. J Mol Biol (2004) 1.12
Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester. J Am Chem Soc (2008) 1.11
Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition. Nucleic Acids Res (2008) 1.11
The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles. PLoS One (2012) 1.11
The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase. J Biol Chem (2002) 1.11
Total synthesis and biological evaluation of the cytotoxic resin glycosides ipomoeassin A-F and analogues. Chemistry (2009) 1.11
Numerical study of the effect of the noseleaf on biosonar beamforming in a horseshoe bat. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 1.10
A novel type of geosmin biosynthesis in myxobacteria. J Org Chem (2005) 1.10
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. Cancer Res (2012) 1.08
Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells. Protein Eng Des Sel (2004) 1.08
In vivo evidence for a prodrug activation mechanism during colibactin maturation. Chembiochem (2013) 1.08
Rational design of a bimodular model system for the investigation of heterocyclization in nonribosomal peptide biosynthesis. Chem Biol (2004) 1.07
Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol. Oncogene (2005) 1.07
Origin and evolution of a novel DnaA-like plasmid replication type in Rhodobacterales. Mol Biol Evol (2010) 1.07
15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist. Mol Pharmacol (2009) 1.05
Molecular and phenotypic analyses reveal the non-identity of the Phaeobacter gallaeciensis type strain deposits CIP 105210T and DSM 17395. Int J Syst Evol Microbiol (2013) 1.05
Nonribosomal peptide biosynthesis: point mutations and module skipping lead to chemical diversity. Angew Chem Int Ed Engl (2006) 1.04
Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases. Chem Biol (2003) 1.04
Transcriptional profiling identifies functional interactions of TGF β and PPAR β/δ signaling: synergistic induction of ANGPTL4 transcription. J Biol Chem (2010) 1.04
3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation. J Bacteriol (2006) 1.03
Biosynthesis and identification of volatiles released by the myxobacterium Stigmatella aurantiaca. Chembiochem (2005) 1.03
Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Mol Pharmacol (2010) 1.02
Improved seamless mutagenesis by recombineering using ccdB for counterselection. Nucleic Acids Res (2013) 1.01
Time to retire--time to die? A prospective cohort study of the effects of early retirement on long-term survival. Soc Sci Med (2009) 1.01
A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. Chembiochem (2005) 1.01
Unusual carbon fixation gives rise to diverse polyketide extender units. Nat Chem Biol (2011) 1.01
Biosynthesis of the myxobacterial antibiotic corallopyronin A. Chembiochem (2010) 1.01
Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity. Angew Chem Int Ed Engl (2014) 1.00
The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles. Genome Biol (2005) 1.00
Mutational analysis of the myxovirescin biosynthetic gene cluster reveals novel insights into the functional elaboration of polyketide backbones. Chembiochem (2007) 0.99
Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum. J Am Chem Soc (2008) 0.98
Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography-electrospray ionisation-time-of-flight mass spectrometry and compound-based principal component analysis. Anal Chim Acta (2008) 0.98
Ligand-mediated regulation of peroxisome proliferator-activated receptor (PPAR) beta/delta: a comparative analysis of PPAR-selective agonists and all-trans retinoic acid. Mol Pharmacol (2008) 0.98
Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus. Chembiochem (2009) 0.97
Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate. J Am Chem Soc (2002) 0.97
Characterisation, genome size and genetic manipulation of the myxobacterium Sorangium cellulosum So ce56. Arch Microbiol (2002) 0.97
Aurafuron A and B, new bioactive polyketides from Stigmatella aurantiaca and Archangium gephyra (Myxobacteria). Fermentation, isolation, physico-chemical properties, structure and biological activity. J Antibiot (Tokyo) (2005) 0.97
Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium. Genome Res (2012) 0.96
Mutation in elongation factor G confers resistance to the antibiotic argyrin in the opportunistic pathogen Pseudomonas aeruginosa. Chembiochem (2012) 0.96
A brief tour of myxobacterial secondary metabolism. Bioorg Med Chem (2008) 0.96
Evidence for the mode of action of the highly cytotoxic Streptomyces polyketide kendomycin. Chembiochem (2007) 0.95
From genetic diversity to metabolic unity: studies on the biosynthesis of aurafurones and aurafuron-like structures in myxobacteria and streptomycetes. J Mol Biol (2007) 0.95
Bacterial type III polyketide synthases: phylogenetic analysis and potential for the production of novel secondary metabolites by heterologous expression in pseudomonads. Arch Microbiol (2006) 0.95
Expanded phylogeny of myxobacteria and evidence for cultivation of the 'unculturables'. Mol Phylogenet Evol (2010) 0.95
Reconstitution of the myxothiazol biosynthetic gene cluster by Red/ET recombination and heterologous expression in Myxococcus xanthus. Appl Environ Microbiol (2006) 0.95
De novo peptide sequencing by tandem MS using complementary CID and electron transfer dissociation. Electrophoresis (2009) 0.95
Myxobacterial natural product assembly lines: fascinating examples of curious biochemistry. Nat Prod Rep (2007) 0.95
Direct cloning, genetic engineering, and heterologous expression of the syringolin biosynthetic gene cluster in E. coli through Red/ET recombineering. Chembiochem (2012) 0.95
Noseleaf dynamics during pulse emission in horseshoe bats. PLoS One (2012) 0.95