Published in J Bacteriol on April 01, 2006
Biosynthesis of caffeic acid in Escherichia coli using its endogenous hydroxylase complex. Microb Cell Fact (2012) 1.64
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Biosynthesis of plant-specific phenylpropanoids by construction of an artificial biosynthetic pathway in Escherichia coli. J Ind Microbiol Biotechnol (2011) 1.06
Structural determinants and modulation of substrate specificity in phenylalanine-tyrosine ammonia-lyases. Chem Biol (2006) 1.04
Artificial biosynthesis of phenylpropanoic acids in a tyrosine overproducing Escherichia coli strain. Microb Cell Fact (2012) 1.02
Mechanism of 4-nitrophenol oxidation in Rhodococcus sp. Strain PN1: characterization of the two-component 4-nitrophenol hydroxylase and regulation of its expression. J Bacteriol (2008) 1.02
A horizontal gene transfer at the origin of phenylpropanoid metabolism: a key adaptation of plants to land. Biol Direct (2009) 0.98
Identification, characterization and functional expression of a tyrosine ammonia-lyase and its mutants from the photosynthetic bacterium Rhodobacter sphaeroides. J Ind Microbiol Biotechnol (2007) 0.95
Bioactive oligosaccharide natural products. Nat Prod Rep (2014) 0.89
Production of hydroxycinnamoyl anthranilates from glucose in Escherichia coli. Microb Cell Fact (2013) 0.87
Highly Active and Specific Tyrosine Ammonia-Lyases from Diverse Origins Enable Enhanced Production of Aromatic Compounds in Bacteria and Saccharomyces cerevisiae. Appl Environ Microbiol (2015) 0.84
Initiation of the flexirubin biosynthesis in Chitinophaga pinensis. Microb Biotechnol (2014) 0.81
Production of hydroxycinnamoyl-shikimates and chlorogenic acid in Escherichia coli: production of hydroxycinnamic acid conjugates. Microb Cell Fact (2013) 0.81
Mimicking a natural pathway for de novo biosynthesis: natural vanillin production from accessible carbon sources. Sci Rep (2015) 0.80
Complete genome sequence of Saccharothrix espanaensis DSM 44229(T) and comparison to the other completely sequenced Pseudonocardiaceae. BMC Genomics (2012) 0.80
Biological synthesis of coumarins in Escherichia coli. Microb Cell Fact (2015) 0.80
Heterologous production of curcuminoids. Microbiol Mol Biol Rev (2015) 0.78
Bacterial synthesis of N-hydroxycinnamoyl phenethylamines and tyramines. Microb Cell Fact (2015) 0.77
Fermentation products of solvent tolerant marine bacterium Moraxella spp. MB1 and its biotechnological applications in salicylic acid bioconversion. PLoS One (2013) 0.77
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Organ-Specific Quantitative Genetics and Candidate Genes of Phenylpropanoid Metabolism in Brassica oleracea. Front Plant Sci (2016) 0.75
Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus. Microb Cell Fact (2015) 0.75
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Improvement of antioxidant and defense properties of Tomato (var. Pusa Rohini) by application of bioaugmented compost. Saudi J Biol Sci (2014) 0.75
Rewriting the lignin roadmap. Curr Opin Plant Biol (2002) 2.37
CYP98A3 from Arabidopsis thaliana is a 3'-hydroxylase of phenolic esters, a missing link in the phenylpropanoid pathway. J Biol Chem (2001) 2.32
The Arabidopsis REF8 gene encodes the 3-hydroxylase of phenylpropanoid metabolism. Plant J (2002) 2.14
Changes in secondary metabolism and deposition of an unusual lignin in the ref8 mutant of Arabidopsis. Plant J (2002) 1.98
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Structural and catalytic properties of the four phenylalanine ammonia-lyase isoenzymes from parsley (Petroselinum crispum Nym.). Eur J Biochem (1994) 1.59
A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis. J Am Chem Soc (2003) 1.42
Characterization of a bacterial tyrosine ammonia lyase, a biosynthetic enzyme for the photoactive yellow protein. FEBS Lett (2002) 1.42
Inactivation, complementation, and heterologous expression of encP, a novel bacterial phenylalanine ammonia-lyase gene. J Biol Chem (2002) 1.36
The gene stlA encodes a phenylalanine ammonia-lyase that is involved in the production of a stilbene antibiotic in Photorhabdus luminescens TT01. Microbiology (2005) 1.29
4-Hydroxycinnamic Acid Hydroxylase and Polyphenolase Activities in Sorghum vulgare. Plant Physiol (1972) 1.27
Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile. Biochemistry (1999) 1.27
Crystal structure of phenylalanine ammonia lyase: multiple helix dipoles implicated in catalysis. Biochemistry (2004) 1.23
Analysis of genes involved in 6-deoxyhexose biosynthesis and transfer in Saccharopolyspora erythraea. Mol Gen Genet (2000) 1.22
Kinetic analysis of the 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis. Biochemistry (2003) 1.16
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures. Arch Biochem Biophys (1987) 1.13
Biochemical characterization of a prokaryotic phenylalanine ammonia lyase. J Bacteriol (2005) 1.13
Saccharomicins, novel heptadecaglycoside antibiotics produced by Saccharothrix espanaensis: antibacterial and mechanistic activities. Antimicrob Agents Chemother (2000) 1.07
Characterization of the active site of histidine ammonia-lyase from Pseudomonas putida. Eur J Biochem (2001) 1.04
An active site homology model of phenylalanine ammonia-lyase from Petroselinum crispum. Eur J Biochem (2002) 1.04
Friedel-Crafts-type mechanism for the enzymatic elimination of ammonia from histidine and phenylalanine. Angew Chem Int Ed Engl (2005) 1.04
Phylogenetic analysis of Saccharothrix and related taxa: proposal for Actinosynnemataceae fam. nov. Int J Syst Evol Microbiol (2000) 1.01
High-performance liquid chromatographic determination of enantiomeric amino acids and amino alcohols after derivatization with o-phthaldialdehyde and various chiral mercaptans. Application to peptide hydrolysates. J Chromatogr (1987) 1.00
Elicitor induction of a microsomal 5-O-(4-coumaroyl)shikimate 3'-hydroxylase in parsley cell suspension cultures. Arch Biochem Biophys (1985) 0.94
Arabidopsis CYP98A3 mediating aromatic 3-hydroxylation. Developmental regulation of the gene, and expression in yeast. Plant Physiol (2002) 0.93
Purification and characterization of p-coumaroyl-D-glucose hydroxylase of sweet potato (Ipomoea batatas) roots. Arch Biochem Biophys (1991) 0.91
Detection and characterization of p-coumaric acid hydroxylase in mung bean, Vigna mungo, seedlings. J Biochem (1989) 0.91
Expression of the landomycin biosynthetic gene cluster in a PKS mutant of Streptomyces fradiae is dependent on the coexpression of a putative transcriptional activator gene. FEMS Microbiol Lett (2004) 0.84
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
GeneTrail--advanced gene set enrichment analysis. Nucleic Acids Res (2007) 5.10
Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting. Nat Biotechnol (2012) 2.54
Complete genome sequence of the myxobacterium Sorangium cellulosum. Nat Biotechnol (2007) 2.43
Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork. Nat Prod Rep (2006) 2.25
Ear deformations give bats a physical mechanism for fast adaptation of ultrasonic beam patterns. Phys Rev Lett (2011) 2.22
Evolutionary implications of bacterial polyketide synthases. Mol Biol Evol (2005) 2.06
The sensitivity of polar ozone depletion to proposed geoengineering schemes. Science (2008) 2.05
The impact of bacterial genomics on natural product research. Angew Chem Int Ed Engl (2005) 1.70
A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene. Chem Biol (2013) 1.59
Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5. Chem Biol (2006) 1.56
Formation of novel secondary metabolites by bacterial multimodular assembly lines: deviations from textbook biosynthetic logic. Curr Opin Chem Biol (2005) 1.51
Myxovirescin A biosynthesis is directed by hybrid polyketide synthases/nonribosomal peptide synthetase, 3-hydroxy-3-methylglutaryl-CoA synthases, and trans-acting acyltransferases. Chembiochem (2006) 1.46
Myxobacteria: proficient producers of novel natural products with various biological activities--past and future biotechnological aspects with the focus on the genus Sorangium. J Biotechnol (2003) 1.44
Biosynthetic pathway of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines. J Bacteriol (2005) 1.43
Discovering the hidden secondary metabolome of Myxococcus xanthus: a study of intraspecific diversity. Appl Environ Microbiol (2008) 1.40
Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes. J Virol (2003) 1.39
Recent developments towards the heterologous expression of complex bacterial natural product biosynthetic pathways. Curr Opin Biotechnol (2005) 1.36
Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus. Chembiochem (2004) 1.35
Production of the antifungal isochromanone ajudazols A and B in Chondromyces crocatus Cm c5: biosynthetic machinery and cytochrome P450 modifications. Angew Chem Int Ed Engl (2008) 1.32
The cyclase-associated protein CAP as regulator of cell polarity and cAMP signaling in Dictyostelium. Mol Biol Cell (2003) 1.30
Structure and action of the C-C bond-forming glycosyltransferase UrdGT2 involved in the biosynthesis of the antibiotic urdamycin. J Mol Biol (2007) 1.28
Mixed-polarization phenotype of ascites-associated macrophages in human ovarian carcinoma: correlation of CD163 expression, cytokine levels and early relapse. Int J Cancer (2013) 1.27
Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene (2004) 1.27
Noseleaf furrows in a horseshoe bat act as resonance cavities shaping the biosonar beam. Phys Rev Lett (2006) 1.27
Deregulation of tumor angiogenesis and blockade of tumor growth in PPARbeta-deficient mice. EMBO J (2007) 1.24
The impact of genomics on the exploitation of the myxobacterial secondary metabolome. Nat Prod Rep (2009) 1.23
Myxobacterial secondary metabolites: bioactivities and modes-of-action. Nat Prod Rep (2010) 1.23
Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ). PLoS One (2011) 1.23
Interferon consensus sequence binding protein (ICSBP; IRF-8) antagonizes BCR/ABL and down-regulates bcl-2. Blood (2003) 1.22
The biosynthetic potential of myxobacteria and their impact in drug discovery. Curr Opin Drug Discov Devel (2009) 1.22
Bacteria of the Roseobacter clade show potential for secondary metabolite production. Microb Ecol (2007) 1.20
Steroid biosynthesis in prokaryotes: identification of myxobacterial steroids and cloning of the first bacterial 2,3(S)-oxidosqualene cyclase from the myxobacterium Stigmatella aurantiaca. Mol Microbiol (2003) 1.20
Myxobacteria--'microbial factories' for the production of bioactive secondary metabolites. Mol Biosyst (2009) 1.19
Heterologous expression of a myxobacterial natural products assembly line in pseudomonads via red/ET recombineering. Chem Biol (2005) 1.18
Comparative genomic analysis of fruiting body formation in Myxococcales. Mol Biol Evol (2010) 1.17
Biosynthesis of the off-flavor 2-methylisoborneol by the myxobacterium Nannocystis exedens. Angew Chem Int Ed Engl (2007) 1.16
Recent advances in the heterologous expression of microbial natural product biosynthetic pathways. Nat Prod Rep (2013) 1.16
Protein-protein interactions in multienzyme megasynthetases. Chembiochem (2008) 1.16
Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta. J Mol Biol (2007) 1.16
The unique DKxanthene secondary metabolite family from the myxobacterium Myxococcus xanthus is required for developmental sporulation. Proc Natl Acad Sci U S A (2006) 1.15
Analysis of myxobacterial secondary metabolism goes molecular. J Ind Microbiol Biotechnol (2006) 1.15
Production of the tubulin destabilizer disorazol in Sorangium cellulosum: biosynthetic machinery and regulatory genes. Chembiochem (2005) 1.15
Synthetic biotechnology to study and engineer ribosomal bottromycin biosynthesis. Chem Biol (2012) 1.14
A genomic screening approach to the structure-guided identification of drug candidates from natural sources. Chembiochem (2007) 1.13
The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers. Angew Chem Int Ed Engl (2004) 1.13
Molecular structure of the rod domain of dictyostelium filamin. J Mol Biol (2004) 1.12
Efficient transfer of two large secondary metabolite pathway gene clusters into heterologous hosts by transposition. Nucleic Acids Res (2008) 1.11
Myxochelin biosynthesis: direct evidence for two- and four-electron reduction of a carrier protein-bound thioester. J Am Chem Soc (2008) 1.11
The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles. PLoS One (2012) 1.11
The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase. J Biol Chem (2002) 1.11
Total synthesis and biological evaluation of the cytotoxic resin glycosides ipomoeassin A-F and analogues. Chemistry (2009) 1.11
A novel type of geosmin biosynthesis in myxobacteria. J Org Chem (2005) 1.10
Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes. J Mol Biol (2005) 1.10
Numerical study of the effect of the noseleaf on biosonar beamforming in a horseshoe bat. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 1.10
The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. Cancer Res (2012) 1.08
Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells. Protein Eng Des Sel (2004) 1.08
In vivo evidence for a prodrug activation mechanism during colibactin maturation. Chembiochem (2013) 1.08
Rational design of a bimodular model system for the investigation of heterocyclization in nonribosomal peptide biosynthesis. Chem Biol (2004) 1.07
Partial downregulation of MAD1 causes spindle checkpoint inactivation and aneuploidy, but does not confer resistance towards taxol. Oncogene (2005) 1.07
Biosynthesis of the terpene phenalinolactone in Streptomyces sp. Tü6071: analysis of the gene cluster and generation of derivatives. Chem Biol (2006) 1.06
Molecular analysis of the kirromycin biosynthetic gene cluster revealed beta-alanine as precursor of the pyridone moiety. Chem Biol (2008) 1.05
15-hydroxyeicosatetraenoic acid is a preferential peroxisome proliferator-activated receptor beta/delta agonist. Mol Pharmacol (2009) 1.05
Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136. FEMS Microbiol Lett (2008) 1.05
Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity. Chem Biol (2002) 1.05
Organisation of the biosynthetic gene cluster and tailoring enzymes in the biosynthesis of the tetracyclic quinone glycoside antibiotic polyketomycin. Chembiochem (2009) 1.04
Nonribosomal peptide biosynthesis: point mutations and module skipping lead to chemical diversity. Angew Chem Int Ed Engl (2006) 1.04
Transcriptional profiling identifies functional interactions of TGF β and PPAR β/δ signaling: synergistic induction of ANGPTL4 transcription. J Biol Chem (2010) 1.04
Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases. Chem Biol (2003) 1.04
3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation. J Bacteriol (2006) 1.03
Biosynthesis and identification of volatiles released by the myxobacterium Stigmatella aurantiaca. Chembiochem (2005) 1.03
Cellular and pharmacological selectivity of the peroxisome proliferator-activated receptor-beta/delta antagonist GSK3787. Mol Pharmacol (2010) 1.02
Improved seamless mutagenesis by recombineering using ccdB for counterselection. Nucleic Acids Res (2013) 1.01
Time to retire--time to die? A prospective cohort study of the effects of early retirement on long-term survival. Soc Sci Med (2009) 1.01
Biosynthesis of the myxobacterial antibiotic corallopyronin A. Chembiochem (2010) 1.01
Glycosyltransferases involved in the biosynthesis of biologically active natural products that contain oligosaccharides. Mol Biosyst (2005) 1.01
A biosynthetic pathway to isovaleryl-CoA in myxobacteria: the involvement of the mevalonate pathway. Chembiochem (2005) 1.01
Iteratively acting glycosyltransferases involved in the hexasaccharide biosynthesis of landomycin A. Chem Biol (2005) 1.01
Unusual carbon fixation gives rise to diverse polyketide extender units. Nat Chem Biol (2011) 1.01
Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity. Angew Chem Int Ed Engl (2014) 1.00
The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles. Genome Biol (2005) 1.00
Glycosyltransferases, important tools for drug design. Curr Top Med Chem (2008) 0.99
Mutational analysis of the myxovirescin biosynthetic gene cluster reveals novel insights into the functional elaboration of polyketide backbones. Chembiochem (2007) 0.99
Generation of novel landomycins M and O through targeted gene disruption. Chembiochem (2005) 0.99
The avilamycin resistance determinants AviRa and AviRb methylate 23S rRNA at the guanosine 2535 base and the uridine 2479 ribose. Mol Microbiol (2003) 0.98
Change in knowledge and skills of Year 3 undergraduates in evidence-based medicine seminars. Med Educ (2005) 0.98
Stereochemical determination and complex biosynthetic assembly of etnangien, a highly potent RNA polymerase inhibitor from the myxobacterium Sorangium cellulosum. J Am Chem Soc (2008) 0.98
Efficient mining of myxobacterial metabolite profiles enabled by liquid chromatography-electrospray ionisation-time-of-flight mass spectrometry and compound-based principal component analysis. Anal Chim Acta (2008) 0.98
Ligand-mediated regulation of peroxisome proliferator-activated receptor (PPAR) beta/delta: a comparative analysis of PPAR-selective agonists and all-trans retinoic acid. Mol Pharmacol (2008) 0.98
Identification of additional players in the alternative biosynthesis pathway to isovaleryl-CoA in the myxobacterium Myxococcus xanthus. Chembiochem (2009) 0.97
Aurafuron A and B, new bioactive polyketides from Stigmatella aurantiaca and Archangium gephyra (Myxobacteria). Fermentation, isolation, physico-chemical properties, structure and biological activity. J Antibiot (Tokyo) (2005) 0.97
Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate. J Am Chem Soc (2002) 0.97
Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717. Chembiochem (2003) 0.96