ASD: the Alternative Splicing Database.

AltTrans: transcript pattern variants annotated for both alternative splicing and alternative polyadenylation. BMC Bioinformatics (2006) 5.50

Biomedical language processing: what's beyond PubMed? Mol Cell (2006) 4.27

E-MSD: an integrated data resource for bioinformatics. Nucleic Acids Res (2005) 4.25

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev (2008) 4.24

ASD: a bioinformatics resource on alternative splicing. Nucleic Acids Res (2006) 3.60

Mutually exclusive splicing of the insect Dscam pre-mRNA directed by competing intronic RNA secondary structures. Cell (2005) 3.53

The architecture of pre-mRNAs affects mechanisms of splice-site pairing. Proc Natl Acad Sci U S A (2005) 2.78

Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicing. BMC Genomics (2004) 2.74

ECgene: genome annotation for alternative splicing. Nucleic Acids Res (2005) 2.06

The Alternative Splicing Gallery (ASG): bridging the gap between genome and transcriptome. Nucleic Acids Res (2004) 1.91

Recognition of unknown conserved alternatively spliced exons. PLoS Comput Biol (2005) 1.77

HOLLYWOOD: a comparative relational database of alternative splicing. Nucleic Acids Res (2006) 1.66

Extraction of transcript diversity from scientific literature. PLoS Comput Biol (2005) 1.64

A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones. Genome Biol (2006) 1.56

SpliceInfo: an information repository for mRNA alternative splicing in human genome. Nucleic Acids Res (2005) 1.39

Cross-kingdom patterns of alternative splicing and splice recognition. Genome Biol (2008) 1.36

A microarray configuration to quantify expression levels and relative abundance of splice variants. Nucleic Acids Res (2005) 1.33

Evolution of alternative and constitutive regions of mammalian 5'UTRs. BMC Genomics (2009) 1.31

Genetic resources, genome mapping and evolutionary genomics of the pig (Sus scrofa). Int J Biol Sci (2007) 1.29

SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis. BMC Bioinformatics (2007) 1.25

Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast. Nucleic Acids Res (2007) 1.24

A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis. PLoS One (2009) 1.23

Genomic splice-site analysis reveals frequent alternative splicing close to the dominant splice site. RNA (2006) 1.22

DEDB: a database of Drosophila melanogaster exons in splicing graph form. BMC Bioinformatics (2004) 1.20

The (in)dependence of alternative splicing and gene duplication. PLoS Comput Biol (2007) 1.17

An artificial riboswitch for controlling pre-mRNA splicing. RNA (2005) 1.17

Differences in the evolutionary history of disease genes affected by dominant or recessive mutations. BMC Genomics (2006) 1.17

TILLING: a shortcut in functional genomics. J Appl Genet (2011) 1.16

At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis. Biochem J (2009) 1.15

Structural genomics analysis of alternative splicing and application to isoform structure modeling. Proc Natl Acad Sci U S A (2005) 1.15

FAST DB: a website resource for the study of the expression regulation of human gene products. Nucleic Acids Res (2005) 1.14

ASPIC: a novel method to predict the exon-intron structure of a gene that is optimally compatible to a set of transcript sequences. BMC Bioinformatics (2005) 1.12

Differential use of signal peptides and membrane domains is a common occurrence in the protein output of transcriptional units. PLoS Genet (2006) 1.12

Specific protein kinase C isoforms as transducers and modulators of insulin signaling. Mol Genet Metab (2006) 1.11

Noisy splicing, more than expression regulation, explains why some exons are subject to nonsense-mediated mRNA decay. BMC Biol (2009) 1.11

Integrating alternative splicing detection into gene prediction. BMC Bioinformatics (2005) 1.09

ASEtrap: a biological method for speeding up the exploration of spliceomes. Genome Res (2006) 1.07

PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa. Hum Mol Genet (2011) 1.04

SR protein 9G8 modulates splicing of tau exon 10 via its proximal downstream intron, a clustering region for frontotemporal dementia mutations. Mol Cell Neurosci (2006) 1.04

Organization and post-transcriptional processing of focal adhesion kinase gene. BMC Genomics (2006) 1.03

Spliceosomes walk the line: splicing errors and their impact on cellular function. RNA Biol (2009) 1.02

ASmodeler: gene modeling of alternative splicing from genomic alignment of mRNA, EST and protein sequences. Nucleic Acids Res (2004) 1.02

Retroviral splicing suppressor sequesters a 3' splice site in a 50S aberrant splicing complex. Mol Cell Biol (2005) 1.00

High-throughput proteomics detection of novel splice isoforms in human platelets. PLoS One (2009) 0.97

Competing upstream 5' splice sites enhance the rate of proximal splicing. Mol Cell Biol (2010) 0.97

Comprehensive splicing graph analysis of alternative splicing patterns in chicken, compared to human and mouse. BMC Genomics (2009) 0.97

MAASE: an alternative splicing database designed for supporting splicing microarray applications. RNA (2005) 0.96

Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase. J Biol Chem (2009) 0.94

Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression. BMC Genomics (2006) 0.92

Sequence features involved in the mechanism of 3' splice junction wobbling. BMC Mol Biol (2010) 0.91

The organization of nucleosomes around splice sites. Nucleic Acids Res (2010) 0.90

Comparative genomic analysis of the arthropod muscle myosin heavy chain genes allows ancestral gene reconstruction and reveals a new type of 'partially' processed pseudogene. BMC Mol Biol (2008) 0.89

Global Plant Stress Signaling: Reactive Oxygen Species at the Cross-Road. Front Plant Sci (2016) 0.88

Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays. BMC Bioinformatics (2011) 0.86

T-STAG: resource and web-interface for tissue-specific transcripts and genes. Nucleic Acids Res (2005) 0.86

Width of gene expression profile drives alternative splicing. PLoS One (2008) 0.85

A heroin addiction severity-associated intronic single nucleotide polymorphism modulates alternative pre-mRNA splicing of the μ opioid receptor gene OPRM1 via hnRNPH interactions. J Neurosci (2014) 0.84

Multiple splice variants within the bovine silver homologue (SILV) gene affecting coat color in cattle indicate a function additional to fibril formation in melanophores. BMC Genomics (2007) 0.84

Identification of alternative 5'/3' splice sites based on the mechanism of splice site competition. Nucleic Acids Res (2006) 0.83

The evolution of alternative splicing in the Pax family: the view from the Basal chordate amphioxus. J Mol Evol (2008) 0.83

Splice-mediated Variants of Proteins (SpliVaP) - data and characterization of changes in signatures among protein isoforms due to alternative splicing. BMC Genomics (2008) 0.82

MIsoMine: a genome-scale high-resolution data portal of expression, function and networks at the splice isoform level in the mouse. Database (Oxford) (2015) 0.82

Novel alternative splicing isoform biomarkers identification from high-throughput plasma proteomics profiling of breast cancer. BMC Syst Biol (2013) 0.82

A procedure for identifying homologous alternative splicing events. BMC Bioinformatics (2007) 0.81

Genome-wide analysis of alternative splicing in cow: implications in bovine as a model for human diseases. BMC Genomics (2009) 0.81

ASePCR: alternative splicing electronic RT-PCR in multiple tissues and organs. Nucleic Acids Res (2005) 0.80

Functional characterization and identification of mouse Rad51d splice variants. BMC Mol Biol (2009) 0.80

A method for similarity search of genomic positional expression using CAGE. PLoS Genet (2006) 0.79

A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion. J Biol Chem (2012) 0.79

Spontaneous symmetry breaking in genome evolution. Nucleic Acids Res (2008) 0.78

Identification of tumor-associated cassette exons in human cancer through EST-based computational prediction and experimental validation. Mol Cancer (2010) 0.78

IsoSVM--distinguishing isoforms and paralogs on the protein level. BMC Bioinformatics (2006) 0.77

Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration. BMC Bioinformatics (2006) 0.75

SVC: structured visualization of evolutionary sequence conservation. Nucleic Acids Res (2005) 0.75

Extraction, integration and analysis of alternative splicing and protein structure distributed information. BMC Bioinformatics (2009) 0.75

Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet (2000) 336.52

Initial sequencing and analysis of the human genome. Nature (2001) 212.86

Creating the gene ontology resource: design and implementation. Genome Res (2001) 55.73

The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. Nucleic Acids Res (2003) 52.80

Mechanisms of alternative pre-messenger RNA splicing. Annu Rev Biochem (2003) 21.11

Ensembl 2002: accommodating comparative genomics. Nucleic Acids Res (2003) 12.26

GenBank. Nucleic Acids Res (2003) 9.60

Pre-mRNA splicing and human disease. Genes Dev (2003) 9.13

Alternative pre-mRNA splicing: the logic of combinatorial control. Trends Biochem Sci (2000) 7.54

Alternative splicing and genome complexity. Nat Genet (2001) 7.30

Genome-wide detection of alternative splicing in expressed sequences of human genes. Nucleic Acids Res (2001) 7.27

The EMBL Nucleotide Sequence Database: major new developments. Nucleic Acids Res (2003) 7.17

Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation. Annu Rev Genet (1998) 7.15

Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell (2000) 6.92

Frequent alternative splicing of human genes. Genome Res (1999) 6.68

eVOC: a controlled vocabulary for unifying gene expression data. Genome Res (2003) 5.41

Gene structure prediction and alternative splicing analysis using genomically aligned ESTs. Genome Res (2001) 5.38

Genew: the human gene nomenclature database. Nucleic Acids Res (2002) 5.09

EST comparison indicates 38% of human mRNAs contain possible alternative splice forms. FEBS Lett (2000) 4.96

ASAP: the Alternative Splicing Annotation Project. Nucleic Acids Res (2003) 2.83

Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human. Hum Mol Genet (2002) 2.67

An alternative-exon database and its statistical analysis. DNA Cell Biol (2000) 2.51

Conservation of human alternative splice events in mouse. Nucleic Acids Res (2003) 2.35

Signals and their transduction pathways regulating alternative splicing: a new dimension of the human genome. Hum Mol Genet (2002) 1.98

AsMamDB: an alternative splice database of mammals. Nucleic Acids Res (2001) 1.85

ASDB: database of alternatively spliced genes. Nucleic Acids Res (2000) 1.78

Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions. Nucleic Acids Res (2001) 1.65

RNA processing and human disease. Cell Mol Life Sci (2000) 1.52

Prediction and statistical analysis of alternatively spliced exons. Prog Mol Subcell Biol (2003) 1.28

Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol (2002) 1.28

Understanding alternative splicing: towards a cellular code. Nat Rev Mol Cell Biol (2005) 13.21

AltTrans: transcript pattern variants annotated for both alternative splicing and alternative polyadenylation. BMC Bioinformatics (2006) 5.50

The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C. Science (2005) 4.54

ASD: a bioinformatics resource on alternative splicing. Nucleic Acids Res (2006) 3.60

Alternative splicing and disease. Biochim Biophys Acta (2008) 3.47

Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03

ASTD: The Alternative Splicing and Transcript Diversity database. Genomics (2008) 2.72

Conservation of human alternative splice events in mouse. Nucleic Acids Res (2003) 2.35

Human tra2-beta1 autoregulates its protein concentration by influencing alternative splicing of its pre-mRNA. Hum Mol Genet (2004) 2.23

Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. Cell Metab (2011) 2.08

Function of alternative splicing. Gene (2012) 2.00

Pre-mRNA secondary structures influence exon recognition. PLoS Genet (2007) 1.92

The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing. Hum Mol Genet (2010) 1.83

The molecular basis for the lack of immunostimulatory activity of vertebrate DNA. J Immunol (2003) 1.67

A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones. Genome Biol (2006) 1.56

Genotype-phenotype databases: challenges and solutions for the post-genomic era. Nat Rev Genet (2009) 1.52

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease. J Neurochem (2005) 1.51

The YTH domain is a novel RNA binding domain. J Biol Chem (2010) 1.45

The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button. BMC Bioinformatics (2010) 1.42

Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene. Cancer Res (2006) 1.34

Substances that can change alternative splice-site selection. Biochem Soc Trans (2008) 1.34

Protein phosphatase 1 binds to the RNA recognition motif of several splicing factors and regulates alternative pre-mRNA processing. Hum Mol Genet (2007) 1.33

Expression of splicing factors in human ovarian cancer. Oncol Rep (2004) 1.31

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. EMBO J (2010) 1.28

Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA Cell Biol (2002) 1.28

YTH: a new domain in nuclear proteins. Trends Biochem Sci (2002) 1.25

Ischemia induces a translocation of the splicing factor tra2-beta 1 and changes alternative splicing patterns in the brain. J Neurosci (2002) 1.24

Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. J Biol Chem (2009) 1.23

Mutations in tau gene exon 10 associated with FTDP-17 alter the activity of an exonic splicing enhancer to interact with Tra2 beta. J Biol Chem (2003) 1.22

Molecular basis of purine-rich RNA recognition by the human SR-like protein Tra2-β1. Nat Struct Mol Biol (2011) 1.22

Processing of snoRNAs as a new source of regulatory non-coding RNAs: snoRNA fragments form a new class of functional RNAs. Bioessays (2012) 1.22

Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism. Biochem Biophys Res Commun (2002) 1.19

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. J Neurochem (2004) 1.17

Tau exons 2 and 10, which are misregulated in neurodegenerative diseases, are partly regulated by silencers which bind a SRp30c.SRp55 complex that either recruits or antagonizes htra2beta1. J Biol Chem (2005) 1.15

Regulation of TRKB surface expression by brain-derived neurotrophic factor and truncated TRKB isoforms. J Biol Chem (2002) 1.14

Differential use of signal peptides and membrane domains is a common occurrence in the protein output of transcriptional units. PLoS Genet (2006) 1.12

Emerin interacts in vitro with the splicing-associated factor, YT521-B. Eur J Biochem (2003) 1.12

NordicDB: a Nordic pool and portal for genome-wide control data. Eur J Hum Genet (2010) 1.07

p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1. Mol Cell Neurosci (2004) 1.06

The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation. Hum Mol Genet (2004) 1.04

Pre-mRNA missplicing as a cause of human disease. Prog Mol Subcell Biol (2006) 1.03

Single molecule profiling of tau gene expression in Alzheimer's disease. J Neurochem (2007) 1.02

Direct cloning of double-stranded RNAs from RNase protection analysis reveals processing patterns of C/D box snoRNAs and provides evidence for widespread antisense transcript expression. Nucleic Acids Res (2011) 1.01

miR-27b*, an oxidative stress-responsive microRNA modulates nuclear factor-kB pathway in RAW 264.7 cells. Mol Cell Biochem (2011) 1.01

Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol (2013) 1.00

Rapid generation of splicing reporters with pSpliceExpress. Gene (2008) 0.99

WT1 interacts with the splicing protein RBM4 and regulates its ability to modulate alternative splicing in vivo. Exp Cell Res (2006) 0.97

Positional characterisation of false positives from computational prediction of human splice sites. Nucleic Acids Res (2000) 0.96

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol. Twin Res Hum Genet (2012) 0.95

VarioML framework for comprehensive variation data representation and exchange. BMC Bioinformatics (2012) 0.95

Observ-OM and Observ-TAB: Universal syntax solutions for the integration, search, and exchange of phenotype and genotype information. Hum Mutat (2012) 0.95

The phenotype and genotype experiment object model (PaGE-OM): a robust data structure for information related to DNA variation. Hum Mutat (2009) 0.91

Regulation of alternative splicing by short non-coding nuclear RNAs. RNA Biol (2010) 0.91

The Finnish disease heritage database (FinDis) update-a database for the genes mutated in the Finnish disease heritage brought to the next-generation sequencing era. Hum Mutat (2013) 0.90

The Arabidopsis chromatin modifier ATX1, the myotubularin-like AtMTM and the response to drought. Plant Signal Behav (2009) 0.89

Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNA. J Biol Chem (2011) 0.89

Sudemycin E influences alternative splicing and changes chromatin modifications. Nucleic Acids Res (2014) 0.88

C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res (2011) 0.88

Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain. Gene (2005) 0.86

The 5' untranslated region of the serotonin receptor 2C pre-mRNA generates miRNAs and is expressed in non-neuronal cells. Exp Brain Res (2013) 0.86

Data modeling and data communication in GenomEUtwin. Twin Res (2003) 0.86

Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse. Hum Mol Genet (2008) 0.86

An SRp75/hnRNPG complex interacting with hnRNPE2 regulates the 5' splice site of tau exon 10, whose misregulation causes frontotemporal dementia. Gene (2011) 0.85

Increased soluble CD44 concentrations are associated with larger tumor size and lymph node metastasis in breast cancer patients. J Cancer Res Clin Oncol (2008) 0.83

Genomic checkpoints for exon 10 usage in the luteinizing hormone receptor type 1 and type 2. Mol Endocrinol (2007) 0.83

DARPP-32 binds to tra2-beta1 and influences alternative splicing. Biochim Biophys Acta (2010) 0.82

Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure. Nucleic Acids Res (2013) 0.82

Activated AMPK and prostaglandins are involved in the response to conjugated linoleic acid and are sufficient to cause lipid reductions in adipocytes. J Nutr Biochem (2010) 0.82

Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro. Biochim Biophys Acta (2013) 0.81

Differential regulation of 5' splice variants of the glutamate transporter EAAT2 in an in vivo model of chemical hypoxia induced by 3-nitropropionic acid. J Neurosci Res (2003) 0.81

Alternative splicing-related factor YT521: an independent prognostic factor in endometrial cancer. Int J Gynecol Cancer (2010) 0.81

Diclofenac potassium liquid-filled soft gelatin capsules for the treatment of postbunionectomy pain. Curr Med Res Opin (2010) 0.81

Dehydration stress memory genes of Zea mays; comparison with Arabidopsis thaliana. BMC Plant Biol (2014) 0.80

Conjugated linoleic acid activates AMP-activated protein kinase and reduces adiposity more effectively when used with metformin in mice. J Nutr (2009) 0.80

Molecular characterization of a patient presumed to have prader-willi syndrome. Clin Med Insights Case Rep (2013) 0.80

An assessment of the efficacy and safety of diclofenac potassium liquid-filled capsules in patients with various levels of baseline pain intensity. Curr Med Res Opin (2012) 0.80

XEMBL: distributing EMBL data in XML format. Bioinformatics (2002) 0.80

A retroelement modifies pre-mRNA splicing: the murine Glrb(spa) allele is a splicing signal polymorphism amplified by long interspersed nuclear element insertion. J Biol Chem (2012) 0.79

Hypoxia-dependent mRNA expression pattern of splicing factor YT521 and its impact on oncological important target gene expression. Mol Carcinog (2013) 0.77

Divergent functions of the myotubularin (MTM) homologs AtMTM1 and AtMTM2 in Arabidopsis thaliana: evolution of the plant MTM family. Plant J (2012) 0.77

Correction: Mutations in the 5' NTR and the Non-Structural Protein 3A of the Coxsackievirus B3 Selectively Attenuate Myocarditogenicity. PLoS One (2015) 0.75

RNA splicing meets genetic testing: detection and interpretation of splicing defects in genetic diseases. Eur J Hum Genet (2010) 0.75

Modulation of the membrane-binding projection domain of tau protein: splicing regulation of exon 3. Brain Res Mol Brain Res (2002) 0.75

Herpesvirus infections in rock hyraxes (Procavia capensis). J Vet Diagn Invest (2009) 0.75

Analysis of mutations that influence pre-mRNA splicing. Methods Mol Biol (2011) 0.75

Direct cloning of double-stranded RNAs. Methods Mol Biol (2015) 0.75