Published in J Biol Chem on February 24, 2004
The axonal transport of mitochondria. J Cell Sci (2005) 5.19
Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons. Mol Biol Cell (2006) 3.96
Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors. Proc Natl Acad Sci U S A (2008) 2.79
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci (2012) 2.68
Distal spinal and bulbar muscular atrophy caused by dynactin mutation. Ann Neurol (2005) 2.34
Local modulation of plus-end transport targets herpesvirus entry and egress in sensory axons. Proc Natl Acad Sci U S A (2004) 2.17
Microtubule binding by dynactin is required for microtubule organization but not cargo transport. J Cell Biol (2007) 2.17
Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proc Natl Acad Sci U S A (2007) 2.16
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons. EMBO J (2008) 2.03
A dynein loading zone for retrograde endosome motility at microtubule plus-ends. EMBO J (2006) 1.96
The axonal transport of mitochondria. J Cell Sci (2012) 1.88
Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends Cell Biol (2009) 1.88
Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. Mol Biol Cell (2007) 1.76
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell (2007) 1.67
Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear migration in neural stem cells. Nat Neurosci (2010) 1.66
APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. Curr Biol (2005) 1.64
Dynactin is required for transport initiation from the distal axon. Neuron (2012) 1.59
Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport. J Neurosci (2009) 1.57
Calsyntenin-1 docks vesicular cargo to kinesin-1. Mol Biol Cell (2006) 1.53
A neuron-specific cytoplasmic dynein isoform preferentially transports TrkB signaling endosomes. J Cell Biol (2008) 1.46
Transient binding of dynein controls bidirectional long-range motility of early endosomes. Proc Natl Acad Sci U S A (2011) 1.46
Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments. Mol Biol Cell (2009) 1.41
The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1. Neuron (2016) 1.40
Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell (2011) 1.38
Bidirectional cargo transport: moving beyond tug of war. Nat Rev Mol Cell Biol (2014) 1.32
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Hum Mol Genet (2008) 1.31
Microtubules regulate disassembly of epithelial apical junctions. BMC Cell Biol (2006) 1.31
Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport. J Cell Biol (2013) 1.18
The microtubule plus-end localization of Aspergillus dynein is important for dynein-early-endosome interaction but not for dynein ATPase activation. J Cell Sci (2010) 1.17
Microtubule-associated protein-like binding of the kinesin-1 tail to microtubules. J Biol Chem (2010) 1.17
Retrograde axonal transport and motor neuron disease. J Neurochem (2008) 1.17
Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain (2009) 1.13
Kinesin-3 and dynein cooperate in long-range retrograde endosome motility along a nonuniform microtubule array. Mol Biol Cell (2011) 1.13
Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis. Antioxid Redox Signal (2009) 1.12
Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity. Mol Cell Biol (2014) 1.04
mNUDC is required for plus-end-directed transport of cytoplasmic dynein and dynactins by kinesin-1. EMBO J (2009) 1.01
Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Mol Biol Cell (2012) 1.00
Mechanism and Regulation of Cytoplasmic Dynein. Annu Rev Cell Dev Biol (2015) 1.00
Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease. Proc Natl Acad Sci U S A (2014) 0.99
Kif5B and Kifc1 interact and are required for motility and fission of early endocytic vesicles in mouse liver. Mol Biol Cell (2007) 0.99
Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts. PLoS One (2010) 0.98
Alphaherpesviruses and the cytoskeleton in neuronal infections. Viruses (2011) 0.98
Structural basis for kinesin-1:cargo recognition. Science (2013) 0.97
A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome. EMBO J (2011) 0.96
A simple theoretical model explains dynein's response to load. Biophys J (2005) 0.93
Neurodegenerative mutation in cytoplasmic dynein alters its organization and dynein-dynactin and dynein-kinesin interactions. J Biol Chem (2010) 0.87
The auto-inhibitory domain and ATP-independent microtubule-binding region of Kinesin heavy chain are major functional domains for transport in the Drosophila germline. Development (2013) 0.84
Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon. Biol Open (2012) 0.83
Analyses of dynein heavy chain mutations reveal complex interactions between dynein motor domains and cellular dynein functions. Genetics (2012) 0.82
Molecular motor proteins and amyotrophic lateral sclerosis. Int J Mol Sci (2011) 0.80
Syd/JIP3 and JNK signaling are required for myonuclear positioning and muscle function. PLoS Genet (2014) 0.79
Oatp1a1 requires PDZK1 to traffic to the plasma membrane by selective recruitment of microtubule-based motor proteins. Drug Metab Dispos (2013) 0.79
Unconventional functions of microtubule motors. Arch Biochem Biophys (2012) 0.79
The cytoskeletal protein Ndel1 regulates dynamin 2 GTPase activity. PLoS One (2011) 0.79
A family of RS domain proteins with novel subcellular localization and trafficking. Nucleic Acids Res (2005) 0.77
Recycling of kinesin-1 motors by diffusion after transport. PLoS One (2013) 0.75
Mutant dynactin in motor neuron disease. Nat Genet (2003) 5.28
Differential regulation of dynein and kinesin motor proteins by tau. Science (2008) 4.29
Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat Cell Biol (2006) 3.56
Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport. Curr Biol (2010) 3.16
Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron (2002) 3.08
Axonal transport and neurodegenerative disease. Biochim Biophys Acta (2006) 3.06
Microtubule motors at the intersection of trafficking and transport. Trends Cell Biol (2006) 2.44
Distal spinal and bulbar muscular atrophy caused by dynactin mutation. Ann Neurol (2005) 2.34
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J Cell Biol (2012) 2.30
Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proc Natl Acad Sci U S A (2007) 2.16
Recruitment of dynein to the Jurkat immunological synapse. Proc Natl Acad Sci U S A (2006) 2.15
Microtubule plus-end tracking by CLIP-170 requires EB1. Proc Natl Acad Sci U S A (2009) 2.15
The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization. Mol Biol Cell (2003) 2.13
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation. J Cell Biol (2006) 2.08
Retrograde axonal transport: pathways to cell death? Trends Neurosci (2010) 2.06
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. J Cell Biol (2013) 2.01
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. J Neurosci (2009) 1.90
Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends Cell Biol (2009) 1.88
Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Curr Biol (2013) 1.76
Cytoplasmic dynein nomenclature. J Cell Biol (2005) 1.71
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Dynactin is required for transport initiation from the distal axon. Neuron (2012) 1.59
Regulation of dynactin through the differential expression of p150Glued isoforms. J Biol Chem (2008) 1.54
Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc Natl Acad Sci U S A (2012) 1.47
Dynein drives nuclear rotation during forward progression of motile fibroblasts. J Cell Sci (2008) 1.37
Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells. J Cell Sci (2012) 1.32
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Hum Mol Genet (2008) 1.31
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Mol Biol Cell (2004) 1.30
The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci (2014) 1.28
Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport. J Neurosci (2013) 1.25
Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons. Neuroreport (2005) 1.25
Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes. Mol Biol Cell (2010) 1.22
Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol (2009) 1.18
Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly. Traffic (2007) 1.16
Dynein tethers and stabilizes dynamic microtubule plus ends. Curr Biol (2012) 1.16
Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor. PLoS Biol (2013) 1.15
Microtubule binding proteins CLIP-170, EB1, and p150Glued form distinct plus-end complexes. FEBS Lett (2006) 1.14
Isolation of murine lung endothelial cells. Am J Physiol Lung Cell Mol Physiol (2009) 1.13
Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons. Neuron (2011) 1.13
Cytoplasmic dynein/dynactin function and dysfunction in motor neurons. Int J Dev Neurosci (2006) 1.11
Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections. Biophys J (2012) 1.03
Neuroligin 1 is dynamically exchanged at postsynaptic sites. J Neurosci (2010) 1.02
Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest (2013) 1.01
Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport. Hum Gene Ther (2014) 0.98
Dynein interacts with the neural cell adhesion molecule (NCAM180) to tether dynamic microtubules and maintain synaptic density in cortical neurons. J Biol Chem (2013) 0.98
PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact. Mol Biol Cell (2002) 0.95
Special delivery: dynamic targeting via cortical capture of microtubules. Dev Cell (2007) 0.91
Autophagosome assembly and cargo capture in the distal axon. Autophagy (2012) 0.90
Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken) (2013) 0.87
MAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons. Autophagy (2014) 0.86
SnapShot: axonal transport. Cell (2012) 0.82
Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria. Autophagy (2015) 0.81
Synaptic vesicle distribution by conveyor belt. Cell (2012) 0.79
Intracellular transport: new tools provide insights into multi-motor transport. Curr Biol (2012) 0.79
Myosin learns to recruit AMPA receptors. Cell (2008) 0.76
Dynein at odd angles? Nat Cell Biol (2010) 0.75
Tangled NUDELs? Nat Cell Biol (2004) 0.75