Published in J Biol Chem on August 19, 2013
The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1. Neuron (2016) 1.40
Rabies Virus Hijacks and accelerates the p75NTR retrograde axonal transport machinery. PLoS Pathog (2014) 0.97
Cytoskeletal disruption activates the DLK/JNK pathway, which promotes axonal regeneration and mimics a preconditioning injury. Neurobiol Dis (2015) 0.86
Reciprocal Interactions between Cell Adhesion Molecules of the Immunoglobulin Superfamily and the Cytoskeleton in Neurons. Front Cell Dev Biol (2016) 0.85
Microtubules in neurons as information carriers. J Neurochem (2013) 0.85
A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity. Mol Biol Cell (2014) 0.81
Proteomic Analysis of Dynein-Interacting Proteins in Amyotrophic Lateral Sclerosis Synaptosomes Reveals Alterations in the RNA-Binding Protein Staufen1. Mol Cell Proteomics (2015) 0.80
A conceptual view at microtubule plus end dynamics in neuronal axons. Brain Res Bull (2016) 0.76
ALS Along the Axons - Expression of Coding and Noncoding RNA Differs in Axons of ALS models. Sci Rep (2017) 0.75
Molecular clock regulates daily α1-2-fucosylation of the neural cell adhesion molecule (NCAM) within mouse secondary olfactory neurons. J Biol Chem (2014) 0.75
Receptor-mediated increase in rabies virus axonal transport. Neural Regen Res (2015) 0.75
Diet-induced changes in brain structure and behavior in old gerbils. Nutr Diabetes (2015) 0.75
Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS. Sci Rep (2016) 0.75
Linking cortical microtubule attachment and exocytosis. F1000Res (2017) 0.75
Beyond self-assembly: from microtubules to morphogenesis. Cell (1986) 10.53
Automatic and quantitative measurement of protein-protein colocalization in live cells. Biophys J (2004) 7.62
Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science (1987) 6.48
Production and purification of lentiviral vectors. Nat Protoc (2006) 6.01
Dynactin is required for microtubule anchoring at centrosomes. J Cell Biol (1999) 4.19
Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration. Nat Neurosci (2007) 4.06
Regulators of the cytoplasmic dynein motor. Nat Rev Mol Cell Biol (2009) 4.05
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J Biol Chem (1995) 3.96
Mechanisms of asymmetric cell division: flies and worms pave the way. Nat Rev Mol Cell Biol (2008) 3.69
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron (2009) 3.54
Microtubule targeting of substrate contacts promotes their relaxation and dissociation. J Cell Biol (1999) 3.53
Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature (1994) 3.19
Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation. Nat Cell Biol (2012) 3.08
Dynein binds to beta-catenin and may tether microtubules at adherens junctions. Nat Cell Biol (2001) 3.06
Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol Biol Cell (1997) 3.05
Purification of brain tubulin through two cycles of polymerization-depolymerization in a high-molarity buffer. Protein Expr Purif (2003) 2.76
The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling. J Cell Biol (1998) 2.66
Dynamic instability of microtubules is regulated by force. J Cell Biol (2003) 2.44
Drosophila Futsch regulates synaptic microtubule organization and is necessary for synaptic growth. Neuron (2000) 2.31
Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters. Cell (2012) 2.26
Dynactin is necessary for synapse stabilization. Neuron (2002) 2.21
Recruitment of dynein to the Jurkat immunological synapse. Proc Natl Acad Sci U S A (2006) 2.15
Retrograde axonal transport: pathways to cell death? Trends Neurosci (2010) 2.06
beta III spectrin binds to the Arp1 subunit of dynactin. J Biol Chem (2001) 2.05
Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells. Nat Cell Biol (2009) 2.00
Activity-dependent dynamic microtubule invasion of dendritic spines. J Neurosci (2008) 1.98
Alterations in transmission, vesicle dynamics, and transmitter release machinery at NCAM-deficient neuromuscular junctions. Neuron (2001) 1.96
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. J Neurosci (2009) 1.90
The cortical protein Num1p is essential for dynein-dependent interactions of microtubules with the cortex. J Cell Biol (2000) 1.87
Rat cortical neurons in cell culture: culture methods, cell morphology, electrophysiology, and synapse formation. Brain Res (1978) 1.87
Spartin regulates synaptic growth and neuronal survival by inhibiting BMP-mediated microtubule stabilization. Neuron (2013) 1.83
PSA-NCAM is required for activity-induced synaptic plasticity. Neuron (1996) 1.81
E-MAP-115 (ensconsin) associates dynamically with microtubules in vivo and is not a physiological modulator of microtubule dynamics. J Cell Sci (1999) 1.69
Mechanism for astral microtubule capture by cortical Bud6p priming spindle polarity in S. cerevisiae. Curr Biol (2012) 1.63
Dynactin is required for transport initiation from the distal axon. Neuron (2012) 1.59
Microtubules in dendritic spine development. J Neurosci (2008) 1.54
Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine. J Clin Invest (2005) 1.39
An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan. Cell (2008) 1.37
Synaptic strength as a function of post- versus presynaptic expression of the neural cell adhesion molecule NCAM. Neuron (2000) 1.32
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Hum Mol Genet (2008) 1.31
Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. J Cell Biol (2009) 1.28
Regulated offloading of cytoplasmic dynein from microtubule plus ends to the cortex. Dev Cell (2011) 1.27
Coordinating mitosis with cell polarity: Molecular motors at the cell cortex. Semin Cell Dev Biol (2010) 1.27
Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol (2006) 1.22
The characterization and localization of the glutamate receptor subunit GluR1 in the rat brain. J Neurosci (1991) 1.21
NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex. J Cell Biol (2006) 1.18
Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly. Traffic (2007) 1.16
Distinct roles of different neural cell adhesion molecule (NCAM) isoforms in synaptic maturation revealed by analysis of NCAM 180 kDa isoform-deficient mice. J Neurosci (2004) 1.16
Dynein tethers and stabilizes dynamic microtubule plus ends. Curr Biol (2012) 1.16
A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice. Hum Mol Genet (2008) 1.09
Structural and functional alterations of neuromuscular junctions in NCAM-deficient mice. J Neurosci (2000) 1.06
Dissociation of double-headed cytoplasmic dynein into single-headed species and its motile properties. Cell Motil Cytoskeleton (2004) 1.05
Microtubule plus-end tracking proteins in differentiated mammalian cells. Int J Biochem Cell Biol (2007) 1.00
NCAM 180 acting via a conserved C-terminal domain and MLCK is essential for effective transmission with repetitive stimulation. Neuron (2005) 1.00
Presynaptic microtubules and their association with synaptic vesicles. Proc R Soc Lond B Biol Sci (1975) 0.98
Immunoelectron-microscopic localization of the 180 kD component of the neural cell adhesion molecule N-CAM in postsynaptic membranes. J Comp Neurol (1989) 0.94
Selective targeting of different neural cell adhesion molecule isoforms during motoneuron myotube synapse formation in culture and the switch from an immature to mature form of synaptic vesicle cycling. J Neurosci (2007) 0.94
Immunohistological localization of the neural adhesion molecules L1 and N-CAM in the developing hippocampus of the mouse. J Neurocytol (1990) 0.94
Organization and reorganization of neuromuscular junctions in mice lacking neural cell adhesion molecule, tenascin-C, or fibroblast growth factor-5. J Neurosci (1998) 0.93
Dynamic microtubules promote synaptic NMDA receptor-dependent spine enlargement. PLoS One (2011) 0.93
Restoration of synaptic plasticity and learning in young and aged NCAM-deficient mice by enhancing neurotransmission mediated by GluN2A-containing NMDA receptors. J Neurosci (2012) 0.92
Special delivery: dynamic targeting via cortical capture of microtubules. Dev Cell (2007) 0.91
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1. PLoS One (2011) 0.91
Intrinsic disorder in dynein intermediate chain modulates its interactions with NudE and dynactin. J Biol Chem (2012) 0.90
The synaptic cytoskeleton in development and disease. Dev Neurobiol (2012) 0.90
Stathmin is required for stability of the Drosophila neuromuscular junction. J Neurosci (2011) 0.89
Neural cell adhesion molecule is required for stability of reinnervated neuromuscular junctions. Eur J Neurosci (2010) 0.88
Microtubule plus-end tracking protein CLASP2 regulates neuronal polarity and synaptic function. J Neurosci (2012) 0.84
Effects of diet on synaptic vesicle release in dynactin complex mutants: a mechanism for improved vitality during motor disease. Aging Cell (2012) 0.83
Microtubules in synapses of the retina. J Neurocytol (1976) 0.82
Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons. Neurochem Int (2012) 0.80
Immobilized pool of NCAM180 in the postsynaptic membrane is homeostatically replenished by the flux of NCAM180 from extrasynaptic regions. J Biol Chem (2011) 0.78
Synaptic vesicles and microtubules in frog motor endplates. Proc R Soc Lond B Biol Sci (1978) 0.77
Mutant dynactin in motor neuron disease. Nat Genet (2003) 5.28
Differential regulation of dynein and kinesin motor proteins by tau. Science (2008) 4.29
Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat Cell Biol (2006) 3.56
Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport. Curr Biol (2010) 3.16
Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron (2005) 3.09
Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron (2002) 3.08
Axonal transport and neurodegenerative disease. Biochim Biophys Acta (2006) 3.06
Microtubule motors at the intersection of trafficking and transport. Trends Cell Biol (2006) 2.44
Distal spinal and bulbar muscular atrophy caused by dynactin mutation. Ann Neurol (2005) 2.34
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J Cell Biol (2012) 2.30
Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proc Natl Acad Sci U S A (2007) 2.16
Recruitment of dynein to the Jurkat immunological synapse. Proc Natl Acad Sci U S A (2006) 2.15
Microtubule plus-end tracking by CLIP-170 requires EB1. Proc Natl Acad Sci U S A (2009) 2.15
The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization. Mol Biol Cell (2003) 2.13
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation. J Cell Biol (2006) 2.08
Retrograde axonal transport: pathways to cell death? Trends Neurosci (2010) 2.06
Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve. Neuron (2008) 2.04
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. J Cell Biol (2013) 2.01
A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. J Biol Chem (2004) 1.97
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. J Neurosci (2009) 1.90
Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends Cell Biol (2009) 1.88
Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Curr Biol (2013) 1.76
Cytoplasmic dynein nomenclature. J Cell Biol (2005) 1.71
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective. Mol Cell Neurosci (2005) 1.59
Dynactin is required for transport initiation from the distal axon. Neuron (2012) 1.59
Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase. J Mol Biol (2006) 1.57
Signaling to transcription networks in the neuronal retrograde injury response. Sci Signal (2010) 1.57
Regulation of dynactin through the differential expression of p150Glued isoforms. J Biol Chem (2008) 1.54
Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc Natl Acad Sci U S A (2012) 1.47
Dynein drives nuclear rotation during forward progression of motile fibroblasts. J Cell Sci (2008) 1.37
Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells. J Cell Sci (2012) 1.32
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Hum Mol Genet (2008) 1.31
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Mol Biol Cell (2004) 1.30
The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci (2014) 1.28
Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport. J Neurosci (2013) 1.25
Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons. Neuroreport (2005) 1.25
An extensive genetic program occurring during postnatal growth in multiple tissues. Endocrinology (2008) 1.24
Huntingtin coordinates the dynein-mediated dynamic positioning of endosomes and lysosomes. Mol Biol Cell (2010) 1.22
Microtubules tethered at epithelial cell junctions by dynein facilitate efficient junction assembly. Traffic (2007) 1.16
Dynein tethers and stabilizes dynamic microtubule plus ends. Curr Biol (2012) 1.16
Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor. PLoS Biol (2013) 1.15
Microtubule binding proteins CLIP-170, EB1, and p150Glued form distinct plus-end complexes. FEBS Lett (2006) 1.14
Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons. Neuron (2011) 1.13
Cytoplasmic dynein/dynactin function and dysfunction in motor neurons. Int J Dev Neurosci (2006) 1.11
Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections. Biophys J (2012) 1.03
Neuroligin 1 is dynamically exchanged at postsynaptic sites. J Neurosci (2010) 1.02
Disruption of CEP290 microtubule/membrane-binding domains causes retinal degeneration. J Clin Invest (2013) 1.01
Adeno-associated virus serotypes 1, 8, and 9 share conserved mechanisms for anterograde and retrograde axonal transport. Hum Gene Ther (2014) 0.98
PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact. Mol Biol Cell (2002) 0.95
Special delivery: dynamic targeting via cortical capture of microtubules. Dev Cell (2007) 0.91
Autophagosome assembly and cargo capture in the distal axon. Autophagy (2012) 0.90
Establishing a novel knock-in mouse line for studying neuronal cytoplasmic dynein under normal and pathologic conditions. Cytoskeleton (Hoboken) (2013) 0.87
MAPK8IP1/JIP1 regulates the trafficking of autophagosomes in neurons. Autophagy (2014) 0.86
WIS-NeuroMath enables versatile high throughput analyses of neuronal processes. Dev Neurobiol (2012) 0.85
SnapShot: axonal transport. Cell (2012) 0.82
Temporal dynamics of PARK2/parkin and OPTN/optineurin recruitment during the mitophagy of damaged mitochondria. Autophagy (2015) 0.81
Synaptic vesicle distribution by conveyor belt. Cell (2012) 0.79
Intracellular transport: new tools provide insights into multi-motor transport. Curr Biol (2012) 0.79
Myosin learns to recruit AMPA receptors. Cell (2008) 0.76
Dynein at odd angles? Nat Cell Biol (2010) 0.75
Tangled NUDELs? Nat Cell Biol (2004) 0.75