Published in J Neurosci on September 22, 2010
Overview of glutamatergic neurotransmission in the nervous system. Pharmacol Biochem Behav (2011) 1.18
Synaptic regulation of microtubule dynamics in dendritic spines by calcium, F-actin, and drebrin. J Neurosci (2013) 1.07
BDNF-induced increase of PSD-95 in dendritic spines requires dynamic microtubule invasions. J Neurosci (2011) 1.05
CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses. Nat Neurosci (2013) 0.95
Dynamic microtubules promote synaptic NMDA receptor-dependent spine enlargement. PLoS One (2011) 0.93
Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains. Neuron (2015) 0.93
Casting a net on dendritic spines: the extracellular matrix and its receptors. Dev Neurobiol (2011) 0.90
A combined transgenic proteomic analysis and regulated trafficking of neuroligin-2. J Biol Chem (2014) 0.89
Neuroligin 2 is expressed in synapses established by cholinergic cells in the mouse brain. PLoS One (2013) 0.89
Microtubules in neurons as information carriers. J Neurochem (2013) 0.85
Fluoxetine increases plasticity and modulates the proteomic profile in the adult mouse visual cortex. Sci Rep (2015) 0.81
Specific sets of intrinsic and extrinsic factors drive excitatory and inhibitory circuit formation. Neuroscientist (2011) 0.78
The interplay between synaptic activity and neuroligin function in the CNS. Biomed Res Int (2015) 0.78
Immobilized pool of NCAM180 in the postsynaptic membrane is homeostatically replenished by the flux of NCAM180 from extrasynaptic regions. J Biol Chem (2011) 0.78
Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions. J Neurosci (2013) 0.78
Breaking down to build up: Neuroligin's C-terminal domain strengthens the synapse. J Cell Biol (2016) 0.76
Of microtubules and memory: implications for microtubule dynamics in dendrites and spines. Mol Biol Cell (2017) 0.75
A model for regulation by SynGAP-α1 of binding of synaptic proteins to PDZ-domain 'Slots' in the postsynaptic density. Elife (2016) 0.75
The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. Elife (2016) 0.75
Dynamic Control of Synaptic Adhesion and Organizing Molecules in Synaptic Plasticity. Neural Plast (2017) 0.75
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch (1981) 134.60
Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23
Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons. Cell (2000) 7.48
Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron (2000) 7.15
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol (1997) 6.57
Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature (1998) 6.29
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes. Nat Neurosci (2000) 6.10
Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins. Cell (2004) 6.08
Neuroligin 1: a splice site-specific ligand for beta-neurexins. Cell (1995) 5.97
Neuroligins determine synapse maturation and function. Neuron (2006) 5.70
Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proc Natl Acad Sci U S A (1999) 5.39
Control of excitatory and inhibitory synapse formation by neuroligins. Science (2005) 5.06
Molecular motors and mechanisms of directional transport in neurons. Nat Rev Neurosci (2005) 4.46
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science (2000) 4.14
Rapid redistribution of synaptic PSD-95 in the neocortex in vivo. PLoS Biol (2006) 4.12
Binding of neuroligins to PSD-95. Science (1997) 3.88
Neurexin mediates the assembly of presynaptic terminals. Nat Neurosci (2003) 3.83
Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron (2009) 3.54
Extrasynaptic membrane trafficking regulated by GluR1 serine 845 phosphorylation primes AMPA receptors for long-term potentiation. J Biol Chem (2005) 3.44
Internalization of ionotropic glutamate receptors in response to mGluR activation. Nat Neurosci (2001) 3.34
Dynein: An ancient motor protein involved in multiple modes of transport. J Neurobiol (2004) 3.30
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature (2002) 3.16
Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron (2002) 3.08
Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Nat Neurosci (2007) 2.90
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr Biol (2001) 2.89
Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1. J Neurophysiol (2001) 2.76
Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior. J Neurosci (2010) 2.57
Microtubule motors at the intersection of trafficking and transport. Trends Cell Biol (2006) 2.44
Disruption of KIF17-Mint1 interaction by CaMKII-dependent phosphorylation: a molecular model of kinesin-cargo release. Nat Cell Biol (2007) 2.40
SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment. Nat Cell Biol (2007) 2.35
Dynein is required for receptor sorting and the morphogenesis of early endosomes. Nat Cell Biol (2006) 2.33
Regulation of CNS synapses by neuronal MHC class I. Proc Natl Acad Sci U S A (2007) 2.25
The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus. Neuropharmacology (1998) 2.16
The complexity of PDZ domain-mediated interactions at glutamatergic synapses: a case study on neuroligin. Neuropharmacology (2004) 2.13
Synaptic accumulation of PSD-95 and synaptic function regulated by phosphorylation of serine-295 of PSD-95. Neuron (2007) 2.04
Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J Neurosci (2000) 2.04
Activity-dependent dynamic microtubule invasion of dendritic spines. J Neurosci (2008) 1.98
Dynein motors transport activated Trks to promote survival of target-dependent neurons. Nat Neurosci (2004) 1.83
Forskolin-induced LTP in the CA1 hippocampal region is NMDA receptor dependent. J Neurophysiol (2003) 1.70
Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci (2007) 1.68
Silencing of neuroligin function by postsynaptic neurexins. J Neurosci (2007) 1.60
Neuroligin-1 is required for normal expression of LTP and associative fear memory in the amygdala of adult animals. Proc Natl Acad Sci U S A (2008) 1.54
Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes. J Neurosci (2002) 1.45
PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling. J Cell Biol (2008) 1.43
Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus. Hippocampus (2010) 1.39
Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton. EMBO J (2006) 1.39
Postsynaptic Neuroligin1 regulates presynaptic maturation. Proc Natl Acad Sci U S A (2009) 1.31
Functional excitatory synapses in HEK293 cells expressing neuroligin and glutamate receptors. J Neurophysiol (2003) 1.26
Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometry. Proteomics (2005) 1.24
Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol (2006) 1.22
The characterization and localization of the glutamate receptor subunit GluR1 in the rat brain. J Neurosci (1991) 1.21
Neuroligin1: a cell adhesion molecule that recruits PSD-95 and NMDA receptors by distinct mechanisms during synaptogenesis. Neural Dev (2009) 1.18
Essential cooperation of N-cadherin and neuroligin-1 in the transsynaptic control of vesicle accumulation. Proc Natl Acad Sci U S A (2010) 1.18
Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors. Proc Natl Acad Sci U S A (2010) 1.15
SAP family proteins. Biochem Biophys Res Commun (2000) 1.07
Albumin endocytosis in OK cells: dependence on actin and microtubules and regulation by protein kinases. Am J Physiol (1997) 1.04
Distribution of members of the PSD-95 family of MAGUK proteins at the synaptic region of inner and outer hair cells of the guinea pig cochlea. Synapse (2001) 0.94
Neuronal depolarization modifies motor protein mobility. Neuroscience (2009) 0.81
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol (2004) 16.08
Mutant dynactin in motor neuron disease. Nat Genet (2003) 5.28
Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron (2006) 4.80
Differential regulation of dynein and kinesin motor proteins by tau. Science (2008) 4.29
Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. J Neurochem (2006) 3.67
Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nat Neurosci (2010) 3.67
Processive bidirectional motion of dynein-dynactin complexes in vitro. Nat Cell Biol (2006) 3.56
PDZ domain proteins: plug and play! Sci STKE (2003) 3.38
Synaptic plasticity at hippocampal mossy fibre synapses. Nat Rev Neurosci (2005) 3.26
Motor coordination via a tug-of-war mechanism drives bidirectional vesicle transport. Curr Biol (2010) 3.16
Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron (2002) 3.08
Axonal transport and neurodegenerative disease. Biochim Biophys Acta (2006) 3.06
Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron (2004) 2.76
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat Neurosci (2007) 2.54
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Dev (2004) 2.49
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J Neurosci (2002) 2.46
Microtubule motors at the intersection of trafficking and transport. Trends Cell Biol (2006) 2.44
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature (2012) 2.36
Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis. Nat Med (2006) 2.34
Distal spinal and bulbar muscular atrophy caused by dynactin mutation. Ann Neurol (2005) 2.34
High cholesterol level is essential for myelin membrane growth. Nat Neurosci (2005) 2.34
Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes. Nat Genet (2007) 2.30
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons. J Cell Biol (2012) 2.30
Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol (2009) 2.17
Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proc Natl Acad Sci U S A (2007) 2.16
Recruitment of dynein to the Jurkat immunological synapse. Proc Natl Acad Sci U S A (2006) 2.15
Microtubule plus-end tracking by CLIP-170 requires EB1. Proc Natl Acad Sci U S A (2009) 2.15
The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization. Mol Biol Cell (2003) 2.13
A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation. Am J Hum Genet (2007) 2.13
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation. J Cell Biol (2006) 2.08
Retrograde axonal transport: pathways to cell death? Trends Neurosci (2010) 2.06
Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation. Science (2010) 2.03
Clinical efficacy and safety of an implantable cardioverter-defibrillator lead with a floating atrial sensing dipole. Pacing Clin Electrophysiol (2013) 2.02
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors. J Cell Biol (2013) 2.01
Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton. Trends Neurosci (2010) 2.00
Proteomic analysis of in vivo phosphorylated synaptic proteins. J Biol Chem (2004) 1.99
A key enzyme in the biogenesis of lysosomes is a protease that regulates cholesterol metabolism. Science (2011) 1.98
A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. J Biol Chem (2004) 1.97
The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults. Neuron (2012) 1.97
Loss of the chloride channel ClC-7 leads to lysosomal storage disease and neurodegeneration. EMBO J (2005) 1.96
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci (2010) 1.93
Evolutionary expansion and anatomical specialization of synapse proteome complexity. Nat Neurosci (2008) 1.91
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration. J Neurosci (2009) 1.90
Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness. EMBO J (2006) 1.88
Huntingtin as an essential integrator of intracellular vesicular trafficking. Trends Cell Biol (2009) 1.88
Local cytoskeletal and organelle interactions impact molecular-motor- driven early endosomal trafficking. Curr Biol (2013) 1.76
Oligomerization of KCC2 correlates with development of inhibitory neurotransmission. J Neurosci (2006) 1.75
Ancillary subunits associated with voltage-dependent K+ channels. Physiol Rev (2010) 1.74
Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. J Neurosci (2004) 1.74
The role of neuronal complexes in human X-linked brain diseases. Am J Hum Genet (2007) 1.71
Cytoplasmic dynein nomenclature. J Cell Biol (2005) 1.71
Phosphatidylinositol 3-kinase regulates the induction of long-term potentiation through extracellular signal-related kinase-independent mechanisms. J Neurosci (2003) 1.70
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci (2007) 1.68
Synaptic scaffold evolution generated components of vertebrate cognitive complexity. Nat Neurosci (2012) 1.67
The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour. Mol Syst Biol (2006) 1.66
Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proc Natl Acad Sci U S A (2003) 1.66
Notch1 control of oligodendrocyte differentiation in the spinal cord. J Cell Biol (2002) 1.65
RIM-binding protein, a central part of the active zone, is essential for neurotransmitter release. Science (2011) 1.59
Dynactin is required for transport initiation from the distal axon. Neuron (2012) 1.59
Regulation of dynactin through the differential expression of p150Glued isoforms. J Biol Chem (2008) 1.54
Mediation of hippocampal mossy fiber long-term potentiation by presynaptic Ih channels. Science (2002) 1.51
Opposing effects of PSD-93 and PSD-95 on long-term potentiation and spike timing-dependent plasticity. J Physiol (2008) 1.50
Phosphoproteomic analysis of the mouse brain cytosol reveals a predominance of protein phosphorylation in regions of intrinsic sequence disorder. Mol Cell Proteomics (2008) 1.48
Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors. Proc Natl Acad Sci U S A (2012) 1.47
Axonal gap junctions between principal neurons: a novel source of network oscillations, and perhaps epileptogenesis. Rev Neurosci (2002) 1.46
PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. J Neurosci (2009) 1.46
Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes. J Neurosci (2002) 1.45
Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability. Proc Natl Acad Sci U S A (2007) 1.45
An improved mouse line for Cre-induced cell ablation due to diphtheria toxin A, expressed from the Rosa26 locus. Genesis (2006) 1.44
Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6. Proc Natl Acad Sci U S A (2006) 1.44
Confirmed rare copy number variants implicate novel genes in schizophrenia. Biochem Soc Trans (2010) 1.42
Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold. EMBO J (2003) 1.42
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration. FASEB J (2009) 1.41
Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination. Mol Cell Biol (2004) 1.40
Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton. EMBO J (2006) 1.39
Profilin2 contributes to synaptic vesicle exocytosis, neuronal excitability, and novelty-seeking behavior. EMBO J (2007) 1.38
Leukoencephalopathy upon disruption of the chloride channel ClC-2. J Neurosci (2007) 1.38
Dynein drives nuclear rotation during forward progression of motile fibroblasts. J Cell Sci (2008) 1.37
Glutamine uptake by neurons: interaction of protons with system a transporters. J Neurosci (2002) 1.37
The origin and evolution of synapses. Nat Rev Neurosci (2009) 1.35
Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. Am J Psychiatry (2010) 1.34
Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity. J Neurosci (2009) 1.34
Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells. J Cell Sci (2012) 1.32
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin. Hum Mol Genet (2008) 1.31
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
The interaction of neurofilaments with the microtubule motor cytoplasmic dynein. Mol Biol Cell (2004) 1.30
The ubiquitin ligase Rnf6 regulates local LIM kinase 1 levels in axonal growth cones. Genes Dev (2005) 1.30
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell (2009) 1.29
The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci (2014) 1.28
Single-trial phase precession in the hippocampus. J Neurosci (2009) 1.27
Evolution of synapse complexity and diversity. Annu Rev Neurosci (2012) 1.27