Published in Am J Hum Genet on April 02, 2004
The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet (2005) 4.02
Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Mol Psychiatry (2008) 2.07
Identification of a schizophrenia-associated functional noncoding variant in NOS1AP. Am J Psychiatry (2009) 1.85
Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder. PLoS Med (2005) 1.44
Nitric oxide synthase 1 adaptor protein, a protein implicated in schizophrenia, controls radial migration of cortical neurons. Biol Psychiatry (2014) 1.40
Oxidative stress in schizophrenia: an integrated approach. Neurosci Biobehav Rev (2010) 1.38
Finding schizophrenia genes. J Clin Invest (2005) 1.28
Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. Arch Gen Psychiatry (2010) 1.24
New roles of carboxypeptidase E in endocrine and neural function and cancer. Endocr Rev (2012) 1.23
Improvements to bead-based oligonucleotide ligation SNP genotyping assays. Biotechniques (2008) 1.04
NOS1AP regulates dendrite patterning of hippocampal neurons through a carboxypeptidase E-mediated pathway. J Neurosci (2009) 1.04
Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia. Am J Hum Genet (2004) 1.03
Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biol Psychiatry (2006) 1.00
Detection of reciprocal quantitative trait loci for acute ethanol withdrawal and ethanol consumption in heterogeneous stock mice. Psychopharmacology (Berl) (2008) 0.98
Effects of updating linkage evidence across subsets of data: reanalysis of the autism genetic resource exchange data set. Am J Hum Genet (2005) 0.98
Heritability of neurocognitive traits in familial schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2009) 0.97
Mismatch negativity and cognitive performance for the prediction of psychosis in subjects with at-risk mental state. PLoS One (2013) 0.95
NOS1AP in schizophrenia. Curr Psychiatry Rep (2008) 0.94
Association of RGS2 and RGS5 variants with schizophrenia symptom severity. Schizophr Res (2008) 0.94
Evidence for a role of the NOS1AP (CAPON) gene in schizophrenia and its clinical dimensions: an association study in a South American population isolate. Hum Hered (2008) 0.92
NOS1AP associates with Scribble and regulates dendritic spine development. J Neurosci (2010) 0.91
Association of synapsin 2 with schizophrenia in families of Northern European ancestry. Schizophr Res (2007) 0.90
A case of autism and uniparental disomy of chromosome 1. Hum Genet (2005) 0.89
Childhood trauma and genetic factors in familial schizophrenia associated with the NOS1AP gene. Schizophr Res (2010) 0.89
Linkage and linkage disequilibrium scan for autism loci in an extended pedigree from Finland. Hum Mol Genet (2009) 0.88
Genome-wide linkage scan of bipolar disorder in a Colombian population isolate replicates Loci on chromosomes 7p21-22, 1p31, 16p12 and 21q21-22 and identifies a novel locus on chromosome 12q. Hum Hered (2010) 0.87
Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia. Schizophr Res (2008) 0.86
Mechanisms of NOS1AP action on NMDA receptor-nNOS signaling. Front Cell Neurosci (2014) 0.83
Independent replication and initial fine mapping of 3p21-24 in Asperger syndrome. J Med Genet (2006) 0.83
Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controls. BMC Med Genet (2010) 0.82
Tumor necrosis factor promoter haplotype associated with schizophrenia reveals a linked locus on 1q44. Mol Psychiatry (2005) 0.82
Early environmental exposures influence schizophrenia expression even in the presence of strong genetic predisposition. Schizophr Res (2012) 0.81
NOS1AP Functionally Associates with YAP To Regulate Hippo Signaling. Mol Cell Biol (2015) 0.81
Association of RGS4 variants with schizotypy and cognitive endophenotypes at the population level. Behav Brain Funct (2008) 0.81
Does the CAPON gene confer susceptibility to schizophrenia? PLoS Med (2005) 0.80
Genetics of developmental psychiatric disorders: pathways to discovery. J Psychiatry Neurosci (2005) 0.79
FBXL21 association with schizophrenia in Irish family and case-control samples. Am J Med Genet B Neuropsychiatr Genet (2008) 0.79
Basic helix-loop-helix transcription factor NEUROG1 and schizophrenia: effects on illness susceptibility, MRI brain morphometry and cognitive abilities. Schizophr Res (2008) 0.76
Role of nitric oxide and related molecules in schizophrenia pathogenesis: biochemical, genetic and clinical aspects. Front Physiol (2015) 0.75
Copy Number Variations in DISC1 and DISC1-Interacting Partners in Major Mental Illness. Mol Neuropsychiatry (2015) 0.75
The Interaction of TXNIP and AFq1 Genes Increases the Susceptibility of Schizophrenia. Mol Neurobiol (2016) 0.75
A sequencing method based on real-time pyrophosphate. Science (1998) 21.21
Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet (1996) 17.95
Implementing a unified approach to family-based tests of association. Genet Epidemiol (2000) 10.96
GOLD--graphical overview of linkage disequilibrium. Bioinformatics (2000) 9.43
The family based association test method: strategies for studying general genotype--phenotype associations. Eur J Hum Genet (2001) 9.09
A test for linkage and association in general pedigrees: the pedigree disequilibrium test. Am J Hum Genet (2000) 7.70
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain (1999) 5.13
Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22. Science (2000) 4.42
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Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet (2001) 3.73
Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet (2003) 3.61
Multipoint estimation of identity-by-descent probabilities at arbitrary positions among marker loci on general pedigrees. Hum Hered (2001) 3.32
Single-nucleotide polymorphism analysis by pyrosequencing. Anal Biochem (2000) 3.21
Novel neural modulators. Annu Rev Neurosci (2003) 2.91
Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet (2000) 2.85
Linkage of schizophrenia with chromosome 1q loci in Taiwanese families. Mol Psychiatry (2003) 2.43
Correcting for a potential bias in the pedigree disequilibrium test. Am J Hum Genet (2001) 2.23
Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron (2000) 2.20
A genome-wide search for schizophrenia susceptibility genes. Am J Med Genet (1998) 2.07
CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron (1998) 2.05
Evidence for anticipation in schizophrenia. Am J Hum Genet (1994) 1.85
Positive and negative symptoms in families with schizophrenia. Schizophr Res (1993) 1.74
Genetic insights into schizophrenia. Can J Psychiatry (2001) 1.38
Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Proc Natl Acad Sci U S A (2002) 1.27
The synapsins: beyond the regulation of neurotransmitter release. Cell Mol Life Sci (2002) 1.27
Genetic insights into the neurodevelopmental hypothesis of schizophrenia. Schizophr Bull (2001) 1.23
Hypoxic-ischemia-related fetal/neonatal complications and risk of schizophrenia and other nonaffective psychoses: a 19-year longitudinal study. Am J Psychiatry (2000) 1.11
Childhood head injury and expression of schizophrenia in multiply affected families. Arch Gen Psychiatry (2003) 1.08
Fine mapping of the schizophrenia susceptibility locus on chromosome 1q22. Hum Hered (2002) 1.06
Altered transcript expression of NMDA receptor-associated postsynaptic proteins in the thalamus of subjects with schizophrenia. Am J Psychiatry (2003) 1.01
Dexras1/AGS-1 inhibits signal transduction from the Gi-coupled formyl peptide receptor to Erk-1/2 MAP kinases. J Biol Chem (2001) 1.01
Roles of postsynaptic density-95/synapse-associated protein 90 and its interacting proteins in the organization of synapses. Cell Mol Life Sci (1999) 1.00
Nitrosopeptide mapping: a novel methodology reveals s-nitrosylation of dexras1 on a single cysteine residue. Chem Biol (2002) 0.98
Schizophrenia: neural mechanisms for novel therapies. Mol Med (2003) 0.98
1q21-q22 locus is associated with susceptibility to the reality-distortion syndrome of schizophrenia spectrum disorders. Am J Med Genet (2002) 0.96
Anticipation or ascertainment bias in schizophrenia? Penrose's familial mental illness sample. Am J Hum Genet (1997) 0.93
Trinucleotide repeat expansion and neuropsychiatric disease. Arch Gen Psychiatry (1999) 0.89
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QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data. Nucleic Acids Res (2007) 10.08
Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature (2009) 9.29
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Clinical features of 78 adults with 22q11 Deletion Syndrome. Am J Med Genet A (2005) 3.13
The schizophrenia phenotype in 22q11 deletion syndrome. Am J Psychiatry (2003) 3.04
Arrhythmogenic right ventricular cardiomyopathy type 5 is a fully penetrant, lethal arrhythmic disorder caused by a missense mutation in the TMEM43 gene. Am J Hum Genet (2008) 2.84
Copy number variations and risk for schizophrenia in 22q11.2 deletion syndrome. Hum Mol Genet (2008) 2.76
Deletion 17q12 is a recurrent copy number variant that confers high risk of autism and schizophrenia. Am J Hum Genet (2010) 2.70
Psychiatric disorders from childhood to adulthood in 22q11.2 deletion syndrome: results from the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome. Am J Psychiatry (2014) 2.15
A method for accurate detection of genomic microdeletions using real-time quantitative PCR. BMC Genomics (2005) 2.04
Clinical and genetic epidemiology of Bardet-Biedl syndrome in Newfoundland: a 22-year prospective, population-based, cohort study. Am J Med Genet A (2005) 2.03
Schizophrenia and 22q11.2 deletion syndrome. Curr Psychiatry Rep (2008) 2.02
Neurocognitive profile in 22q11 deletion syndrome and schizophrenia. Schizophr Res (2006) 1.89
Identification of a schizophrenia-associated functional noncoding variant in NOS1AP. Am J Psychiatry (2009) 1.85
The impact of implantable cardioverter-defibrillator therapy on survival in autosomal-dominant arrhythmogenic right ventricular cardiomyopathy (ARVD5). J Am Coll Cardiol (2005) 1.83
The co-occurrence of early onset Parkinson disease and 22q11.2 deletion syndrome. Am J Med Genet A (2009) 1.82
Association between early-onset Parkinson disease and 22q11.2 deletion syndrome: identification of a novel genetic form of Parkinson disease and its clinical implications. JAMA Neurol (2013) 1.81
A major susceptibility locus for specific language impairment is located on 13q21. Am J Hum Genet (2002) 1.79
Catechol-O-methyl transferase and expression of schizophrenia in 73 adults with 22q11 deletion syndrome. Biol Psychiatry (2007) 1.63
Incomplete knowledge of the clinical context as a barrier to interpreting incidental genetic research findings. Am J Bioeth (2013) 1.48
Rare copy number variations in adults with tetralogy of Fallot implicate novel risk gene pathways. PLoS Genet (2012) 1.44
Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays. Hum Mol Genet (2013) 1.44
Clinically detectable copy number variations in a Canadian catchment population of schizophrenia. J Psychiatr Res (2010) 1.30
Structural brain abnormalities in patients with schizophrenia and 22q11 deletion syndrome. Biol Psychiatry (2002) 1.27
1q21.1 Microduplication expression in adults. Genet Med (2012) 1.25
Molecular characterization of deletion breakpoints in adults with 22q11 deletion syndrome. Hum Genet (2006) 1.17
Characterization and regulation of the genes for a novel anthranilate 1,2-dioxygenase from Burkholderia cepacia DBO1. J Bacteriol (2003) 1.16
Sex differences in reproductive fitness contribute to preferential maternal transmission of 22q11.2 deletions. J Med Genet (2011) 1.13
Extracardiac features predicting 22q11.2 deletion syndrome in adult congenital heart disease. Int J Cardiol (2008) 1.12
Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures. Hum Mol Genet (2013) 1.11
Childhood head injury and expression of schizophrenia in multiply affected families. Arch Gen Psychiatry (2003) 1.08
Evaluating genetic counseling for family members of individuals with schizophrenia in the molecular age. Schizophr Bull (2012) 1.08
Expression of autism spectrum and schizophrenia in patients with a 22q11.2 deletion. Schizophr Res (2012) 1.08
Clinical applications of schizophrenia genetics: genetic diagnosis, risk, and counseling in the molecular era. Appl Clin Genet (2012) 1.07
Fine mapping of the schizophrenia susceptibility locus on chromosome 1q22. Hum Hered (2002) 1.06
Genotype and cardiovascular phenotype correlations with TBX1 in 1,022 velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome patients. Hum Mutat (2011) 1.05
Association of schizophrenia in 22q11.2 deletion syndrome and gray matter volumetric deficits in the superior temporal gyrus. Am J Psychiatry (2011) 1.03
Association of the PIK4CA schizophrenia-susceptibility gene in adults with the 22q11.2 deletion syndrome. Am J Med Genet B Neuropsychiatr Genet (2009) 1.02
Recognizing a common genetic syndrome: 22q11.2 deletion syndrome. CMAJ (2008) 1.01
Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples. Biol Psychiatry (2006) 1.00
Hippocampal malrotation is associated with chromosome 22q11.2 microdeletion. Can J Neurol Sci (2013) 0.99
Heritability of neurocognitive traits in familial schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2009) 0.97
Evaluating genetic counseling for individuals with schizophrenia in the molecular age. Schizophr Bull (2012) 0.96
miRNA-mediated risk for schizophrenia in 22q11.2 deletion syndrome. Front Genet (2012) 0.96
Novel exon 1 mutations in MECP2 implicate isoform MeCP2_e1 in classical Rett syndrome. Am J Med Genet A (2009) 0.95
The ever-evolving concept of clinical significance and the potential for sins of omission in genetic research. Am J Bioeth (2012) 0.95
Functional outcomes of adults with 22q11.2 deletion syndrome. Genet Med (2012) 0.94
22q11.2 deletion syndrome: attitudes towards disclosing the risk of psychiatric illness. J Genet Couns (2012) 0.93
Increasing genotype-phenotype model determinism: application to bivariate reading/language traits and epistatic interactions in language-impaired families. Hum Hered (2010) 0.92
Movement disorders and other motor abnormalities in adults with 22q11.2 deletion syndrome. Am J Med Genet A (2015) 0.91
Premorbid adjustment and schizophrenia in individuals with 22q11.2 deletion syndrome. Schizophr Res (2013) 0.90
Patterns of cardiac and extracardiac anomalies in adults with tetralogy of fallot. Am Heart J (2011) 0.90
Childhood trauma and genetic factors in familial schizophrenia associated with the NOS1AP gene. Schizophr Res (2010) 0.89
Oct4 is required ~E7.5 for proliferation in the primitive streak. PLoS Genet (2013) 0.89
Mutations in MECP2 exon 1 in classical Rett patients disrupt MECP2_e1 transcription, but not transcription of MECP2_e2. Am J Med Genet B Neuropsychiatr Genet (2011) 0.87
Voxel-based morphometry and automated lobar volumetry: the trade-off between spatial scale and statistical correction. Neuroimage (2009) 0.87
Phenotype matters: the case for careful characterization of relevant traits. Am J Psychiatry (2008) 0.87
Prenatal genetic testing with chromosomal microarray analysis identifies major risk variants for schizophrenia and other later-onset disorders. Am J Psychiatry (2013) 0.86
13q13.1-q13.2 deletion in tetralogy of Fallot: clinical report and a literature review. Int J Cardiol (2010) 0.84
Heritability of schizophrenia and major affective disorder as a function of age, in the presence of strong cohort effects. Eur Arch Psychiatry Clin Neurosci (2005) 0.84
Parental origin, DNA structure, and the schizophrenia spectrum. Am J Psychiatry (2011) 0.83
Genetic covariation underlying reading, language and related measures in a sample selected for specific language impairment. Behav Genet (2010) 0.83
Prevalence of hypocalcaemia and its associated features in 22q11·2 deletion syndrome. Clin Endocrinol (Oxf) (2014) 0.83
Complex congenital heart disease in unaffected relatives of adults with 22q11.2 deletion syndrome. Am J Cardiol (2011) 0.82
Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury. Brain Inj (2010) 0.82
Early environmental exposures influence schizophrenia expression even in the presence of strong genetic predisposition. Schizophr Res (2012) 0.81
Adult neuropsychiatric expression and familial segregation of 2q13 duplications. Am J Med Genet B Neuropsychiatr Genet (2014) 0.80
Overt cleft palate phenotype and TBX1 genotype correlations in velo-cardio-facial/DiGeorge/22q11.2 deletion syndrome patients. Am J Med Genet A (2012) 0.79
Reproductive genetic testing and human genetic variation in the era of genomic medicine. Am J Bioeth (2015) 0.77
PERSONALITY FEATURES AND DISORDER IN THE SUBJECTS IN THE NEW YORK HIGH-RISK PROJECT. J Psychiatr Res (1993) 0.77
Reduced gray matter in the anterior cingulate gyrus in familial schizophrenia: a preliminary report. Schizophr Res (2010) 0.77
Reproductive fitness and genetic transmission of tetralogy of Fallot in the molecular age. Circ Cardiovasc Genet (2014) 0.76