NOS1AP associates with Scribble and regulates dendritic spine development.

Nitric oxide synthase 1 adaptor protein, a protein implicated in schizophrenia, controls radial migration of cortical neurons. Biol Psychiatry (2014) 1.40

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration, and is associated with breast cancer progression. Oncogene (2011) 1.20

Mislocalization of the cell polarity protein scribble promotes mammary tumorigenesis and is associated with basal breast cancer. Cancer Res (2014) 1.02

Immature T-cell clustering and efficient differentiation require the polarity protein Scribble. Proc Natl Acad Sci U S A (2010) 0.88

NOS1AP Functionally Associates with YAP To Regulate Hippo Signaling. Mol Cell Biol (2015) 0.81

Discovery and confirmation of ligand binding specificities of the Schistosoma japonicum polarity protein Scribble. PLoS Negl Trop Dis (2014) 0.79

Overexpression of Isoforms of Nitric Oxide Synthase 1 Adaptor Protein, Encoded by a Risk Gene for Schizophrenia, Alters Actin Dynamics and Synaptic Function. Front Cell Neurosci (2016) 0.76

GIT1 enhances neurite outgrowth by stimulating microtubule assembly. Neural Regen Res (2016) 0.75

Planar cell polarity genes Frizzled3a, Vangl2, and Scribble are required for spinal commissural axon guidance. BMC Neurosci (2016) 0.75

The Hippo component YAP localizes in the nucleus of human papilloma virus positive oropharyngeal squamous cell carcinoma. J Otolaryngol Head Neck Surg (2017) 0.75

Polarity Determinants in Dendritic Spine Development and Plasticity. Neural Plast (2015) 0.75

The Neuronal Protein Neurexin Directly Interacts with the Scribble-Pix Complex to Stimulate F-actin Assembly for Synaptic Vesicle Clustering. J Biol Chem (2017) 0.75

A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem (2003) 29.58

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (2000) 6.44

A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet (2006) 6.39

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors. Mol Cell (1998) 4.82

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell (2008) 3.43

An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers. Neuron (2009) 3.34

Schizophrenia as a disorder of developmentally reduced synaptic connectivity. Arch Gen Psychiatry (2000) 3.32

Neuronal polarity: from extracellular signals to intracellular mechanisms. Nat Rev Neurosci (2007) 3.31

A specificity map for the PDZ domain family. PLoS Biol (2008) 3.16

Establishment of axon-dendrite polarity in developing neurons. Annu Rev Neurosci (2009) 2.73

A novel regulator of p21-activated kinases. J Biol Chem (1998) 2.60

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J Neurosci (2005) 2.48

The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans. Nature (1999) 2.30

Molecular organization of the presynaptic active zone. Cell Tissue Res (2006) 2.22

Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density. Nat Rev Neurosci (2009) 2.22

Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Neuron (2000) 2.20

The polarity protein PAR-3 and TIAM1 cooperate in dendritic spine morphogenesis. Nat Cell Biol (2006) 2.12

Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting. Neuron (2002) 2.05

CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron (1998) 2.05

Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration. Curr Biol (2006) 2.03

Synapse formation is regulated by the signaling adaptor GIT1. J Cell Biol (2003) 2.00

Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex. Neuron (2008) 1.94

Mammalian Scribble forms a tight complex with the betaPIX exchange factor. Curr Biol (2004) 1.89

The PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase. Dev Cell (2008) 1.77

SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS. Nat Neurosci (2006) 1.74

Polarity proteins in axon specification and synaptogenesis. Dev Cell (2005) 1.66

The presynaptic release apparatus is functional in the absence of dendritic contact and highly mobile within isolated axons. Neuron (2003) 1.59

Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains. J Cell Biochem (2006) 1.56

Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22. Am J Hum Genet (2004) 1.55

Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. J Neurosci (2003) 1.51

Colocalization of synapsin and actin during synaptic vesicle recycling. J Cell Biol (2003) 1.50

Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. J Biol Chem (2003) 1.47

Increased expression in dorsolateral prefrontal cortex of CAPON in schizophrenia and bipolar disorder. PLoS Med (2005) 1.44

PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling. J Cell Biol (2008) 1.43

Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays. Mol Cell Biol (2006) 1.41

Nitric oxide is a volume transmitter regulating postsynaptic excitability at a glutamatergic synapse. Neuron (2008) 1.40

Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration. Hum Mol Genet (2008) 1.37

The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. J Biol Chem (2002) 1.28

Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Proc Natl Acad Sci U S A (2002) 1.27

The NGL family of leucine-rich repeat-containing synaptic adhesion molecules. Mol Cell Neurosci (2009) 1.25

Scrib regulates PAK activity during the cell migration process. Hum Mol Genet (2008) 1.17

Regulation of synaptic plasticity and synaptic vesicle dynamics by the PDZ protein Scribble. J Neurosci (2002) 1.16

Leucine-rich repeat proteins of synapses. J Neurosci Res (2007) 1.13

NOS1AP regulates dendrite patterning of hippocampal neurons through a carboxypeptidase E-mediated pathway. J Neurosci (2009) 1.04

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses. Mol Biol Cell (2009) 1.03

A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian Numb. J Biol Chem (2004) 0.87

Post-synaptic density-95 promotes calcium/calmodulin-dependent protein kinase II-mediated Ser847 phosphorylation of neuronal nitric oxide synthase. Biochem J (2003) 0.87

PDZ domain polarity complexes. Curr Biol (2003) 0.85

[The GIT-PIX protein complex: a hub to ARF and Rac/Cdc42 GTPases]. Med Sci (Paris) (2005) 0.76

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature (2002) 37.66

Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol (2007) 8.16

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell (2002) 8.08

Systematic discovery of in vivo phosphorylation networks. Cell (2007) 6.94

PreBIND and Textomy--mining the biomedical literature for protein-protein interactions using a support vector machine. BMC Bioinformatics (2003) 6.31

A global protein kinase and phosphatase interaction network in yeast. Science (2010) 5.95

Dynamic modularity in protein interaction networks predicts breast cancer outcome. Nat Biotechnol (2009) 5.41

Dissecting virulence: systematic and functional analyses of a pathogenicity island. Proc Natl Acad Sci U S A (2004) 5.34

An experimentally derived confidence score for binary protein-protein interactions. Nat Methods (2008) 5.27

Histone recognition and large-scale structural analysis of the human bromodomain family. Cell (2012) 5.15

Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Dev Cell (2006) 4.77

Reading protein modifications with interaction domains. Nat Rev Mol Cell Biol (2006) 4.55

The Hippo pathway regulates Wnt/beta-catenin signaling. Dev Cell (2010) 4.49

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data. Nat Methods (2013) 4.34

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes. Nature (2006) 4.05

Cell signaling in space and time: where proteins come together and when they're apart. Science (2009) 3.88

Linear motif atlas for phosphorylation-dependent signaling. Sci Signal (2008) 3.77

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. Curr Biol (2004) 3.45

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture. Oncogene (2004) 3.44

Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol (2006) 3.42

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. Cell (2006) 3.38

Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. J Exp Med (2002) 3.24

Protein phosphorylation in signaling--50 years and counting. Trends Biochem Sci (2005) 3.19

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. Nat Cell Biol (2003) 3.11

EphB receptor activity suppresses colorectal cancer progression. Nature (2005) 2.84

NetworKIN: a resource for exploring cellular phosphorylation networks. Nucleic Acids Res (2007) 2.69

Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function. Cell (2011) 2.57

The human and mouse complement of SH2 domain proteins-establishing the boundaries of phosphotyrosine signaling. Mol Cell (2006) 2.51

Identification and characterization of NleA, a non-LEE-encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7. Mol Microbiol (2004) 2.51

The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps. Gastrointest Endosc (2011) 2.51

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation. Cell (2008) 2.46

Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. Nat Genet (2004) 2.44

Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype. Nat Biotechnol (2003) 2.34

Temporal regulation of EGF signalling networks by the scaffold protein Shc1. Nature (2013) 2.33

Spondylolisthesis, pelvic incidence, and spinopelvic balance: a correlation study. Spine (Phila Pa 1976) (2004) 2.33

Positive selection of tyrosine loss in metazoan evolution. Science (2009) 2.28

The mammalian septin MSF localizes with microtubules and is required for completion of cytokinesis. Mol Biol Cell (2002) 2.25

Platelet calmodulin levels in adolescent idiopathic scoliosis: do the levels correlate with curve progression and severity? Spine (Phila Pa 1976) (2002) 2.24

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV. EMBO J (2004) 2.24

Post-translational modifications in signal integration. Nat Struct Mol Biol (2010) 2.23

ProHits: integrated software for mass spectrometry-based interaction proteomics. Nat Biotechnol (2010) 2.22

Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis. Cell Metab (2013) 2.21

Hereditary haemochromatosis is unlikely to cause movement disorders--a critical review. J Neurol (2004) 2.17

Podocyte-specific loss of Cdc42 leads to congenital nephropathy. J Am Soc Nephrol (2012) 2.16

Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases. Sci Signal (2009) 2.16

HIV infection does not affect the performance of noninvasive markers of fibrosis for the diagnosis of hepatitis C virus-related liver disease. J Acquir Immune Defic Syndr (2005) 2.13

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell (2011) 2.11

The importance of spino-pelvic balance in L5-s1 developmental spondylolisthesis: a review of pertinent radiologic measurements. Spine (Phila Pa 1976) (2005) 2.10

Phosphotyrosine signaling: evolving a new cellular communication system. Cell (2010) 2.09

Eukaryotic protein domains as functional units of cellular evolution. Sci Signal (2009) 2.06

Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol (2003) 2.03

Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites. BMC Biotechnol (2006) 2.01

WW domains provide a platform for the assembly of multiprotein networks. Mol Cell Biol (2005) 1.97

Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration. Curr Biol (2009) 1.93

Nck proteins maintain the adult glomerular filtration barrier. J Am Soc Nephrol (2009) 1.92

The Sabah Biodiversity Experiment: a long-term test of the role of tree diversity in restoring tropical forest structure and functioning. Philos Trans R Soc Lond B Biol Sci (2011) 1.91

Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release. Proc Natl Acad Sci U S A (2010) 1.91

Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells. Science (2009) 1.91

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. PLoS Biol (2010) 1.90

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor. Nat Biotechnol (2011) 1.90

Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility. Nat Cell Biol (2008) 1.88

Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (2008) 1.86

The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol (2003) 1.86

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease. Cell (2011) 1.83

ShcA signalling is essential for tumour progression in mouse models of human breast cancer. EMBO J (2008) 1.82

Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function. Cell (2012) 1.79

Defining the specificity space of the human SRC homology 2 domain. Mol Cell Proteomics (2007) 1.78

The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling. Nat Cell Biol (2002) 1.77

Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system. J Physiol (2003) 1.76

Elimination of host cell PtdIns(4,5)P(2) by bacterial SigD promotes membrane fission during invasion by Salmonella. Nat Cell Biol (2002) 1.75

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Proc Natl Acad Sci U S A (2009) 1.73

High-throughput phosphotyrosine profiling using SH2 domains. Mol Cell (2007) 1.72

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. Sci Signal (2013) 1.69

A new transcription factor that regulates TNF-alpha gene expression, LITAF, is increased in intestinal tissues from patients with CD and UC. Inflamm Bowel Dis (2006) 1.69

Deciphering arginine methylation: Tudor tells the tale. Nat Rev Mol Cell Biol (2011) 1.69

Polarity proteins in axon specification and synaptogenesis. Dev Cell (2005) 1.66

Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity. Proc Natl Acad Sci U S A (2007) 1.65

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. Nat Cell Biol (2010) 1.64

The Cdc42 effector IRSp53 generates filopodia by coupling membrane protrusion with actin dynamics. J Biol Chem (2008) 1.60