Published in Cell on June 08, 2012
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Increased oxidative metabolism in the Li-Fraumeni syndrome. N Engl J Med (2013) 1.25
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Suppression of host p53 is critical for Plasmodium liver-stage infection. Cell Rep (2013) 1.08
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Copper oxide nanoparticles induced mitochondria mediated apoptosis in human hepatocarcinoma cells. PLoS One (2013) 0.97
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Oct4 maintains the pluripotency of human embryonic stem cells by inactivating p53 through Sirt1-mediated deacetylation. Stem Cells (2014) 0.97
The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction. Cell Rep (2016) 0.96
BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues. Cell Rep (2014) 0.96
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways. Oncogenesis (2014) 0.95
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc Natl Acad Sci U S A (2012) 0.95
Caught in the cross fire: p53 in inflammation. Carcinogenesis (2014) 0.95
Resveratrol inhibits the growth of gastric cancer by inducing G1 phase arrest and senescence in a Sirt1-dependent manner. PLoS One (2013) 0.95
How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis. Bioessays (2013) 0.94
Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism. Oncogene (2013) 0.94
Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase. PLoS One (2013) 0.93
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The role of tumor suppressor p53 in the antioxidant defense and metabolism. Subcell Biochem (2014) 0.90
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Sestrin2 protein positively regulates AKT enzyme signaling and survival in human squamous cell carcinoma and melanoma cells. J Biol Chem (2014) 0.90
p53 as an intervention target for cancer and aging. Pathobiol Aging Age Relat Dis (2013) 0.89
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Embryonic stem cells shed new light on the developmental roles of p53. Cell Biosci (2013) 0.88
p53, a translational regulator: contribution to its tumour-suppressor activity. Oncogene (2015) 0.88
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The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development. Cancer Discov (2015) 0.87
Chemical metabolic inhibitors for the treatment of blood-borne cancers. Anticancer Agents Med Chem (2014) 0.87
Amino-terminal p53 mutations lead to expression of apoptosis proficient p47 and prognosticate better survival, but predispose to tumorigenesis. Proc Natl Acad Sci U S A (2015) 0.87
Targeting tumor suppressor networks for cancer therapeutics. Curr Drug Targets (2014) 0.87
Understanding the non-canonical pathways involved in p53-mediated tumor suppression. Carcinogenesis (2013) 0.86
Formononetin suppresses the proliferation of human non-small cell lung cancer through induction of cell cycle arrest and apoptosis. Int J Clin Exp Pathol (2014) 0.86
Illuminating p53 function in cancer with genetically engineered mouse models. Semin Cell Dev Biol (2014) 0.86
SIRT1 counteracted the activation of STAT3 and NF-κB to repress the gastric cancer growth. Int J Clin Exp Med (2014) 0.86
Recent discoveries in the cycling, growing and aging of the p53 field. Aging (Albany NY) (2012) 0.85
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Mechanisms of ferroptosis. Cell Mol Life Sci (2016) 0.84
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The p53 family grows old. Genes Dev (2012) 0.84
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Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science (2010) 6.04
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Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell (2006) 5.64
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Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol (2005) 4.37
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The pentose cycle and insulin release in mouse pancreatic islets. Biochem J (1972) 2.79
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The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res (2004) 2.56
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The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation. Proc Natl Acad Sci U S A (2005) 2.40
The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein. Trends Cell Biol (2010) 2.33
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Non-invasive prenatal measurement of the fetal genome. Nature (2012) 3.11
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Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell (2011) 2.10
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The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell (2009) 2.04
An intimate collaboration between peroxisomes and lipid bodies. J Cell Biol (2006) 2.04
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev (2008) 2.01
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E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc Natl Acad Sci U S A (2008) 1.97
Lysine succinylation and lysine malonylation in histones. Mol Cell Proteomics (2012) 1.95
Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function. J Biol Chem (2003) 1.92
Hormonal control of androgen receptor function through SIRT1. Mol Cell Biol (2006) 1.91
WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells. Proc Natl Acad Sci U S A (2006) 1.90
Unequal contribution of Akt isoforms in the double-negative to double-positive thymocyte transition. J Immunol (2007) 1.88
IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth. Proc Natl Acad Sci U S A (2007) 1.88
Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Mol Cell (2011) 1.87
2D differential in-gel electrophoresis for the identification of esophageal scans cell cancer-specific protein markers. Mol Cell Proteomics (2002) 1.85
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. J Clin Invest (2012) 1.82
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