High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men.

PubWeight™: 7.11‹?› | Rank: Top 1%

🔗 View Article (PMID 1516192)

Published in Circulation on September 01, 1992

Authors

J T Salonen1, K Nyyssönen, H Korpela, J Tuomilehto, R Seppänen, R Salonen

Author Affiliations

1: Research Institute of Public Health, University of Kuopio, Finland.

Articles citing this

(truncated to the top 100)

Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci U S A (1993) 13.27

Dietary supplements and mortality rate in older women: the Iowa Women's Health Study. Arch Intern Med (2011) 6.69

Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: a systematic review and meta-analysis. Circulation (2010) 5.58

Health effects and prevalence of vegetarianism. West J Med (1994) 2.91

Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc Natl Acad Sci U S A (1993) 2.77

Possible association of a reduction in cardiovascular events with blood donation. Heart (1997) 2.39

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. Arch Toxicol (2010) 2.36

The development of mitochondrial medicine. Proc Natl Acad Sci U S A (1994) 1.68

Iron sucrose accelerates early atherogenesis by increasing superoxide production and upregulating adhesion molecules in CKD. J Am Soc Nephrol (2014) 1.50

Ferritin for the clinician. Blood Rev (2008) 1.46

Workplace conditions, socioeconomic status, and the risk of mortality and acute myocardial infarction: the Kuopio Ischemic Heart Disease Risk Factor Study. Am J Public Health (1997) 1.45

Iron and thrombosis. Ann Hematol (2007) 1.43

Asymptomatic ST-segment depression during exercise testing and the risk of sudden cardiac death in middle-aged men: a population-based follow-up study. Eur Heart J (2009) 1.43

Iron and coronary heart disease. BMJ (1993) 1.35

Negative confounding in the evaluation of toxicity: the case of methylmercury in fish and seafood. Crit Rev Toxicol (2008) 1.34

Low hemoglobin A1c and risk of all-cause mortality among US adults without diabetes. Circ Cardiovasc Qual Outcomes (2010) 1.33

A safe strategy for addition of vitamins and minerals to foods. Eur J Nutr (2005) 1.32

Unprocessed red and processed meats and risk of coronary artery disease and type 2 diabetes--an updated review of the evidence. Curr Atheroscler Rep (2012) 1.29

The significance of haemochromatosis gene mutations in the general population: implications for screening. Gut (1998) 1.25

Effect of Nordic Walking training on iron metabolism in elderly women. Clin Interv Aging (2015) 1.24

Ferritin protects endothelial cells from oxidized low density lipoprotein in vitro. Am J Pathol (1995) 1.22

Hospitalization rates for coronary heart disease in relation to residence near areas contaminated with persistent organic pollutants and other pollutants. Environ Health Perspect (2005) 1.21

Association of serum 25-hydroxyvitamin D with the risk of death in a general older population in Finland. Eur J Nutr (2010) 1.14

Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation. J Clin Invest (1995) 1.10

Increased ferritin gene expression in atherosclerotic lesions. J Clin Invest (1996) 1.07

Associations of serum ferritin and transferrin % saturation with all-cause, cancer, and cardiovascular disease mortality: Third National Health and Nutrition Examination Survey follow-up study. J Prev Med Public Health (2012) 0.99

Excessive body iron stores are not associated with risk of coronary heart disease in women. J Nutr (2008) 0.98

Geochemistry of ground water and the incidence of acute myocardial infarction in Finland. J Epidemiol Community Health (2004) 0.98

Intravenous ferric chloride hexahydrate supplementation induced endothelial dysfunction and increased cardiovascular risk among hemodialysis patients. PLoS One (2012) 0.97

Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis. Gut (1998) 0.95

Poor iron status is more prevalent in Hispanic than in non-Hispanic white older adults in Massachusetts. J Nutr (2007) 0.95

Epidemiological associations between iron and cardiovascular disease and diabetes. Front Pharmacol (2014) 0.94

The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice. Exp Biol Med (Maywood) (2010) 0.93

Correlation of concentrations of selected trace elements with Gleason grade of prostate tissues. J Biol Inorg Chem (2010) 0.92

Iron status is associated with carotid atherosclerotic plaques in middle-aged adults. J Nutr (2010) 0.92

Lipid profile and its association with risk factors for coronary heart disease in the highlanders of Lhasa, Tibet. High Alt Med Biol (2011) 0.92

[Prevention of stroke]. Wien Med Wochenschr (2003) 0.92

Catechol-o-methyltransferase gene polymorphism modifies the effect of coffee intake on incidence of acute coronary events. PLoS One (2006) 0.91

The effect of iron overload on rat plasma and liver oxidant status in vivo. Biochem J (1994) 0.91

Synthesis and antioxidant activities of novel 5-chlorocurcumin, complemented by semiempirical calculations. Bioinorg Chem Appl (2013) 0.90

Lipid-induced changes in intracellular iron homeostasis in vitro and in vivo. J Clin Invest (1995) 0.89

Can low accuracy disease risk predictor models improve health care using decision support systems? Proc AMIA Symp (1998) 0.89

Iron accumulation during cellular senescence in human fibroblasts in vitro. Antioxid Redox Signal (2003) 0.89

Associations of dietary iron intake with mortality from cardiovascular disease: the JACC study. J Epidemiol (2012) 0.89

Functional COMT Val158Met polymorphism, risk of acute coronary events and serum homocysteine: the Kuopio ischaemic heart disease risk factor study. PLoS One (2007) 0.88

Iron deficiency and cardiovascular disease. Nat Rev Cardiol (2015) 0.87

Atherogenesis and iron: from epidemiology to cellular level. Front Pharmacol (2014) 0.87

Serum long-chain n-3 polyunsaturated fatty acids, mercury, and risk of sudden cardiac death in men: a prospective population-based study. PLoS One (2012) 0.87

Acute phase reactants as novel predictors of cardiovascular disease. ISRN Inflamm (2012) 0.87

Iron: protector or risk factor for cardiovascular disease? Still controversial. Nutrients (2013) 0.86

Impaired iron status in aging research. Int J Mol Sci (2012) 0.86

Age-dependent and gender-specific changes in mouse tissue iron by strain. Exp Gerontol (2009) 0.85

Iron metabolism in hemodialyzed patients - a story half told? Arch Med Sci (2014) 0.85

Abnormalities of autonomic nervous control in human hypertension. Cardiovasc Drugs Ther (1994) 0.85

Profound morphological changes in the erythrocytes and fibrin networks of patients with hemochromatosis or with hyperferritinemia, and their normalization by iron chelators and other agents. PLoS One (2014) 0.85

Alcohol consumption and risk of colorectal cancer: the Findrink study. Eur J Epidemiol (2008) 0.84

Association of body iron status with the risk of premature acute myocardial infarction in a Pakistani population. PLoS One (2013) 0.83

The prevalence of haemochromatosis gene mutations in the West of Scotland and their relation to ischaemic heart disease. Heart (2003) 0.83

Iron-induced fibrin in cardiovascular disease. Curr Neurovasc Res (2013) 0.83

An Evaluation of the Clinical Evidence on the Role of Inflammation and Oxidative Stress in Smoking-Mediated Cardiovascular Disease. Biomark Insights (2008) 0.83

The association of biomarkers of iron status with peripheral arterial disease in US adults. BMC Cardiovasc Disord (2009) 0.82

Relation between Body Iron Status and Cardiovascular Risk Factors in Patients with Cardiovascular Disease. Int J Prev Med (2013) 0.82

Iron status in the elderly. Mech Ageing Dev (2013) 0.82

Treatment of anemia in heart failure: potential risks and benefits of intravenous iron therapy in cardiovascular disease. Cardiol Rev (2010) 0.82

γ-Glutamyltransferase and Risk of Sudden Cardiac Death in Middle-Aged Finnish Men: A New Prospective Cohort Study. J Am Heart Assoc (2016) 0.82

Heme Oxygenases in Cardiovascular Health and Disease. Physiol Rev (2016) 0.82

Association of oxidative stress, iron, and centralized fat mass in healthy postmenopausal women. J Womens Health (Larchmt) (2009) 0.81

Prevalence, characteristics, and prognostic significance of HFE gene mutations in type 2 diabetes: the Fremantle Diabetes Study. Diabetes Care (2008) 0.81

Association of dietary iron restriction with left ventricular remodeling after myocardial infarction in mice. Heart Vessels (2015) 0.81

Inflammatory biomarker score and cancer: A population-based prospective cohort study. BMC Cancer (2016) 0.80

Stored iron and ischemic heart disease. Empirical support for a new paradigm. Circulation (1992) 0.80

Free-radical scavenging by tryptophan and its metabolites through electron transfer based processes. J Mol Model (2015) 0.79

Dietary iron intake and body iron stores are associated with risk of coronary heart disease in a meta-analysis of prospective cohort studies. J Nutr (2014) 0.79

On myocardial siderosis and left ventricular dysfunction in hemochromatosis. J Cardiovasc Magn Reson (2013) 0.79

Hemoglobin concentration and risk of cardiovascular disease in Korean men and women - the Korean heart study. J Korean Med Sci (2013) 0.79

HFE mutations in heart disease. Heart Vessels (2008) 0.78

Serum ferritin-a novel risk factor in acute myocardial infarction. Indian Heart J (2012) 0.78

Iron deficiency anemia in heart failure. Heart Fail Rev (2013) 0.78

The relation between body iron store and ferritin, and coronary artery disease. ARYA Atheroscler (2014) 0.78

The association between serum 25-hydroxyvitamin D3 concentration and risk of disease death in men: modification by magnesium intake. Eur J Epidemiol (2015) 0.78

Nordic walking training attenuation of oxidative stress in association with a drop in body iron stores in elderly women. Biogerontology (2017) 0.78

Effects of dietary components on high-density lipoprotein measures in a cohort of 1,566 participants. Nutr Metab (Lond) (2014) 0.77

Iron, platelet function, and coronary heart disease: a possible link? Circulation (1993) 0.76

Association between Serum Iron and the Severity of Coronary Artery Disease. Int Cardiovasc Res J (2013) 0.76

Iron intake and associated factors in general Japanese population: NIPPON DATA80, NIPPON DATA90 and national nutrition monitoring. J Epidemiol (2010) 0.76

Iron stores in regular blood donors in Lagos, Nigeria. J Blood Med (2013) 0.75

The Gordon Wilson Lecture. Plasma cholesterol: atherogenesis and mortality. Trans Am Clin Climatol Assoc (1993) 0.75

High stored iron levels and the risk of myocardial infarction. Circulation (1993) 0.75

Antiplatelet prophylaxis. Consider the protective effect of blood loss from the gut. BMJ (1994) 0.75

Iron and ischemic heart disease. Circulation (1993) 0.75

High stored iron levels. Circulation (1993) 0.75

Associations of Milk Consumption and Vitamin B₂ and Β12 Derived from Milk with Fitness, Anthropometric and Biochemical Indices in Children. The Healthy Growth Study. Nutrients (2016) 0.75

Serum long-chain omega-3 polyunsaturated fatty acids and risk of orthostatic hypotension. Hypertens Res (2016) 0.75

Serum ferritin levels associated with increased risk for developing CHD in a low-income urban population. Public Health Nutr (2012) 0.75

Effects of Environmental Pollutants on Cellular Iron Homeostasis and Ultimate Links to Human Disease. Environ Health Insights (2016) 0.75

Relationship of Lipid Profile and Serum Ferritin levels with Acute Myocardial Infarction. J Clin Diagn Res (2014) 0.75

High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men. Circulation (1993) 0.75

Iron, human growth, and the global epidemic of obesity. Nutrients (2013) 0.75

Serum polyunsaturated fatty acids are not associated with the risk of severe depression in middle-aged Finnish men: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) study. Eur J Nutr (2010) 0.75

Serum iron concentration and plasma oxidant-antioxidant balance in patients with chronic venous insufficency. Med Sci Monit (2011) 0.75

Articles by these authors

Haplotype tagging for the identification of common disease genes. Nat Genet (2001) 11.27

Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet (1997) 9.18

Autoantibody against oxidised LDL and progression of carotid atherosclerosis. Lancet (1992) 7.09

Estimation of contribution of changes in classic risk factors to trends in coronary-event rates across the WHO MONICA Project populations. Lancet (2000) 6.94

Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet (1998) 6.20

Preventing non-insulin-dependent diabetes. Diabetes (1995) 6.16

Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. Systolic Hypertension in Europe Trial Investigators. JAMA (1999) 5.76

Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study. BMJ (2001) 5.40

Early growth and coronary heart disease in later life: longitudinal study. BMJ (2001) 5.25

Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. Diabetologia (1992) 5.25

Catch-up growth in childhood and death from coronary heart disease: longitudinal study. BMJ (1999) 5.17

Worldwide increase in incidence of Type I diabetes--the analysis of the data on published incidence trends. Diabetologia (1999) 5.11

Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project Group. Diabetes Care (2000) 4.62

The community-based strategy to prevent coronary heart disease: conclusions from the ten years of the North Karelia project. Annu Rev Public Health (1985) 4.30

Do cardiovascular risk factors explain the relation between socioeconomic status, risk of all-cause mortality, cardiovascular mortality, and acute myocardial infarction? Am J Epidemiol (1996) 4.23

Change in risk factors for coronary heart disease during 10 years of a community intervention programme (North Karelia project). Br Med J (Clin Res Ed) (1983) 4.00

Mapping genes for NIDDM. Design of the Finland-United States Investigation of NIDDM Genetics (FUSION) Study. Diabetes Care (1998) 3.99

The genetically isolated populations of Finland and sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes. Nat Genet (2000) 3.92

Changes in risk factors explain changes in mortality from ischaemic heart disease in Finland. BMJ (1994) 3.92

The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81

Changes in coronary risk factors during comprehensive five-year community programme to control cardiovascular diseases (North Karelia project). Br Med J (1979) 3.75

Mother's weight in pregnancy and coronary heart disease in a cohort of Finnish men: follow up study. BMJ (1997) 3.63

Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study. Neurology (2001) 3.56

A review of the recent epidemiological data on the worldwide incidence of type 1 (insulin-dependent) diabetes mellitus. World Health Organization DIAMOND Project Group. Diabetologia (1993) 3.35

A European evidence-based guideline for the prevention of type 2 diabetes. Horm Metab Res (2010) 3.15

Prospective randomised trial in 1062 infants of diet low in saturated fat and cholesterol. Lancet (1995) 3.13

The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med (2000) 3.10

Educational level, relative body weight, and changes in their association over 10 years: an international perspective from the WHO MONICA Project. Am J Public Health (2000) 3.08

The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert Consultation. Diabetologia (2009) 3.05

Symptoms of chronic bronchitis and the risk of coronary disease. Lancet (1996) 3.03

Increased nuchal translucency as a marker for fetal chromosomal defects. N Engl J Med (1997) 3.01

Intake of mercury from fish, lipid peroxidation, and the risk of myocardial infarction and coronary, cardiovascular, and any death in eastern Finnish men. Circulation (1995) 2.99

Theory and action for health promotion illustrations from the North Karelia Project. Am J Public Health (1982) 2.95

Twenty-year trends in coronary risk factors in north Karelia and in other areas of Finland. Int J Epidemiol (1994) 2.91

Social class, health behaviour, and mortality among men and women in eastern Finland. BMJ (1995) 2.89

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease. Neuroepidemiology (1998) 2.83

Prospective observational study to assess value of prostate specific antigen as screening test for prostate cancer. BMJ (1995) 2.80

Decline in mortality from coronary heart disease in Finland from 1969 to 1979. Br Med J (Clin Res Ed) (1983) 2.80

Growth in utero and during childhood among women who develop coronary heart disease: longitudinal study. BMJ (1999) 2.78

Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. Circulation (1999) 2.78

Immediate and late benefits of treating very elderly people with hypertension: results from active treatment extension to Hypertension in the Very Elderly randomised controlled trial. BMJ (2011) 2.77

Perceived health status and morbidity and mortality: evidence from the Kuopio ischaemic heart disease risk factor study. Int J Epidemiol (1996) 2.73

Changes in smoking, serum cholesterol and blood pressure levels during a community-based cardiovascular disease prevention program--the North Karelia Project. Am J Epidemiol (1981) 2.72

Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group. Diabetes Care (1998) 2.70

Early adiposity rebound in childhood and risk of Type 2 diabetes in adult life. Diabetologia (2003) 2.60

Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial. J Hypertens (1987) 2.59

Changes in population cholesterol concentrations and other cardiovascular risk factor levels after five years of the non-communicable disease intervention programme in Mauritius. Mauritius Non-communicable Disease Study Group. BMJ (1995) 2.57

Glucose intolerance during diuretic therapy. Results of trial by the European Working Party on Hypertension in the Elderly. Lancet (1978) 2.56

Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Study design and 1-year interim report on the feasibility of the lifestyle intervention programme. Diabetologia (1999) 2.51

Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men. Arch Intern Med (1996) 2.49

Abdominal obesity is associated with increased risk of acute coronary events in men. Eur Heart J (2002) 2.46

Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study. Diabetes Care (1995) 2.44

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study. Diabetologia (2011) 2.43

Impaired fasting glucose or impaired glucose tolerance. What best predicts future diabetes in Mauritius? Diabetes Care (1999) 2.41

Age, body mass index and Type 2 diabetes-associations modified by ethnicity. Diabetologia (2003) 2.37

Ultrasound B-mode imaging in observational studies of atherosclerotic progression. Circulation (1993) 2.31

Two-hour glucose is a better risk predictor for incident coronary heart disease and cardiovascular mortality than fasting glucose. Eur Heart J (2002) 2.31

Increased risk of acute myocardial infarction in carriers of the hemochromatosis gene Cys282Tyr mutation : a prospective cohort study in men in eastern Finland. Circulation (1999) 2.29

Body mass index and the risk of Parkinson disease. Neurology (2006) 2.28

Diagnostic criteria and quality control of the registration of stroke events in the MONICA project. Acta Med Scand Suppl (1988) 2.26

Education and dementia: what lies behind the association? Neurology (2007) 2.26

A gene in the HLA class I region contributes to susceptibility to IDDM in the Finnish population. Childhood Diabetes in Finland (DiMe) Study Group. Diabetologia (1994) 2.25

Diet, nutrition and the prevention of type 2 diabetes. Public Health Nutr (2004) 2.25

Decline in cardiovascular mortality in North Karelia and other parts of Finland. Br Med J (Clin Res Ed) (1986) 2.22

Diabetes, prediabetes and cancer mortality. Diabetologia (2010) 2.22

Physical activity and risk of myocardial infarction, cerebral stroke and death: a longitudinal study in Eastern Finland. Am J Epidemiol (1982) 2.20

Telecommunication and international health research. Am J Epidemiol (1988) 2.19

Nutrient intakes by young children in a prospective randomized trial of a low-saturated fat, low-cholesterol diet. The STRIP Baby Project. Special Turku Coronary Risk Factor Intervention Project for Babies. Arch Pediatr Adolesc Med (1997) 2.16

The hydrolethalus syndrome: delineation of a "new", lethal malformation syndrome based on 28 patients. Clin Genet (1981) 2.15

Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. Arterioscler Thromb (1991) 2.11

Association between body iron stores and the risk of acute myocardial infarction in men. Circulation (1998) 2.10

Relation of leisure-time physical activity and cardiorespiratory fitness to the risk of acute myocardial infarction. N Engl J Med (1994) 2.09

Fetal and childhood growth and hypertension in adult life. Hypertension (2000) 2.09

International trends in mortality from stroke, 1968 to 1994. Stroke (2000) 2.09

Cost-effective analysis of candidate genes using htSNPs: a staged approach. Genes Immun (2004) 2.07

Trends in obesity and energy supply in the WHO MONICA Project. Int J Obes Relat Metab Disord (2004) 2.07

Total cholesterol and the risk of Parkinson disease. Neurology (2008) 2.06

Association between type 1 diabetes and Haemophilus influenzae type b vaccination: birth cohort study. BMJ (1999) 2.06

Socioeconomic status and ischemic stroke: The FINMONICA Stroke Register. Stroke (2001) 2.06

The Meckel syndrome: clinicopathological findings in 67 patients. Am J Med Genet (1984) 2.06

Hopelessness and risk of mortality and incidence of myocardial infarction and cancer. Psychosom Med (1997) 2.06

The effects of physical activity and body mass index on cardiovascular, cancer and all-cause mortality among 47 212 middle-aged Finnish men and women. Int J Obes (Lond) (2005) 2.05

Variation in HLA-associated risks of childhood insulin-dependent diabetes in the Finnish population: II. Haplotype effects. DiMe Study Group. Childhood Diabetes in Finland. Genet Epidemiol (1995) 2.03

Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland. Circulation (1996) 2.02

Serum gamma-glutamyl transferase, self-reported alcohol drinking, and the risk of stroke. Stroke (2000) 2.01

High prevalence of NIDDM and impaired glucose tolerance in Indian, Creole, and Chinese Mauritians. Mauritius Noncommunicable Disease Study Group. Diabetes (1990) 2.01

Improved lifestyle and decreased diabetes risk over 13 years: long-term follow-up of the randomised Finnish Diabetes Prevention Study (DPS). Diabetologia (2012) 1.99

Take action to prevent diabetes--the IMAGE toolkit for the prevention of type 2 diabetes in Europe. Horm Metab Res (2010) 1.99