Published in Am J Physiol Heart Circ Physiol on May 27, 2004
Ablation of myosin-binding protein-C accelerates force development in mouse myocardium. Biophys J (2006) 1.69
Acceleration of stretch activation in murine myocardium due to phosphorylation of myosin regulatory light chain. J Gen Physiol (2006) 1.53
Activation dependence of stretch activation in mouse skinned myocardium: implications for ventricular function. J Gen Physiol (2006) 1.35
Role of myosin heavy chain composition in the stretch activation response of rat myocardium. J Physiol (2006) 1.29
Contributions of stretch activation to length-dependent contraction in murine myocardium. J Gen Physiol (2006) 1.00
The tropomyosin binding region of cardiac troponin T modulates crossbridge recruitment dynamics in rat cardiac muscle fibers. J Mol Biol (2013) 0.88
The C-terminus of troponin T is essential for maintaining the inactive state of regulated actin. Biophys J (2012) 0.88
Myosin cross-bridge dynamics in patients with hypertension and concentric left ventricular remodeling. Circ Heart Fail (2012) 0.86
Effects of low-level α-myosin heavy chain expression on contractile kinetics in porcine myocardium. Am J Physiol Heart Circ Physiol (2011) 0.85
Fluorescence Based Characterization of Calcium Sensitizer Action on the Troponin Complex. Chem Biol Drug Des (2015) 0.78
The effects of slow skeletal troponin I expression in the murine myocardium are influenced by development-related shifts in myosin heavy chain isoform. J Physiol (2012) 0.78
FRET study of the structural and kinetic effects of PKC phosphomimetic cardiac troponin T mutants on thin filament regulation. Arch Biochem Biophys (2014) 0.78
Effect of N-Terminal Extension of Cardiac Troponin I on the Ca(2+) Regulation of ATP Binding and ADP Dissociation of Myosin II in Native Cardiac Myofibrils. Biochemistry (2016) 0.75
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure. Circulation (2006) 4.69
Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice. Circ Res (2002) 2.82
Protein kinase A-mediated acceleration of the stretch activation response in murine skinned myocardium is eliminated by ablation of cMyBP-C. Circ Res (2006) 2.50
Valvular myofibroblast activation by transforming growth factor-beta: implications for pathological extracellular matrix remodeling in heart valve disease. Circ Res (2004) 2.45
Three-dimensional structure of vertebrate cardiac muscle myosin filaments. Proc Natl Acad Sci U S A (2008) 2.39
A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell (2012) 2.35
Myosin crossbridge activation of cardiac thin filaments: implications for myocardial function in health and disease. Circ Res (2004) 2.35
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity. Nature (2012) 2.33
Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun (2009) 2.19
Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. J Proteome Res (2011) 2.17
Genetic variability in forced and voluntary endurance exercise performance in seven inbred mouse strains. J Appl Physiol (1985) (2002) 2.15
Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation. Circ Res (2007) 2.11
Ablation of cardiac myosin-binding protein-C accelerates stretch activation in murine skinned myocardium. Circ Res (2006) 2.10
Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state. Proc Natl Acad Sci U S A (2009) 2.10
Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. Circ Res (2006) 2.09
Acceleration of crossbridge kinetics by protein kinase A phosphorylation of cardiac myosin binding protein C modulates cardiac function. Circ Res (2008) 2.07
Basal myosin light chain phosphorylation is a determinant of Ca2+ sensitivity of force and activation dependence of the kinetics of myocardial force development. Am J Physiol Heart Circ Physiol (2004) 1.93
Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. PLoS Genet (2006) 1.84
Loaded shortening, power output, and rate of force redevelopment are increased with knockout of cardiac myosin binding protein-C. Circ Res (2003) 1.81
Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development. J Physiol (2010) 1.76
Future research directions in idiopathic pulmonary fibrosis: summary of a National Heart, Lung, and Blood Institute working group. Am J Respir Crit Care Med (2002) 1.76
Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci (2005) 1.73
Ablation of myosin-binding protein-C accelerates force development in mouse myocardium. Biophys J (2006) 1.69
Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle. Proc Natl Acad Sci U S A (2006) 1.68
Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun (2006) 1.67
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10. Mol Pain (2005) 1.66
Repeated intrathecal injections of plasmid DNA encoding interleukin-10 produce prolonged reversal of neuropathic pain. Pain (2006) 1.66
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest (2012) 1.59
Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle. J Mol Biol (2008) 1.57
Protein kinase A-mediated phosphorylation of cMyBP-C increases proximity of myosin heads to actin in resting myocardium. Circ Res (2008) 1.55
The cell biology of disease: cellular mechanisms of cardiomyopathy. J Cell Biol (2011) 1.54
Acceleration of stretch activation in murine myocardium due to phosphorylation of myosin regulatory light chain. J Gen Physiol (2006) 1.53
Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. Exp Neurol (2013) 1.52
Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening. Circ Res (2004) 1.52
Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials (2005) 1.51
Competencies: a cure for pre-med curriculum. Science (2011) 1.47
Utrophin binds laterally along actin filaments and can couple costameric actin with sarcolemma when overexpressed in dystrophin-deficient muscle. Mol Biol Cell (2002) 1.44
Designing scaffolds for valvular interstitial cells: cell adhesion and function on naturally derived materials. J Biomed Mater Res A (2004) 1.43
Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy. Dev Cell (2006) 1.43
Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping. Mol Cell Biol (2010) 1.43
Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function. Proc Natl Acad Sci U S A (2013) 1.42
Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. PLoS One (2012) 1.41
SLControl: PC-based data acquisition and analysis for muscle mechanics. Am J Physiol Heart Circ Physiol (2003) 1.36
Activation dependence of stretch activation in mouse skinned myocardium: implications for ventricular function. J Gen Physiol (2006) 1.35
Radial displacement of myosin cross-bridges in mouse myocardium due to ablation of myosin binding protein-C. J Mol Biol (2006) 1.33
Binding of myosin binding protein-C to myosin subfragment S2 affects contractility independent of a tether mechanism. Circ Res (2004) 1.33
Fatty acids identified in the Burmese python promote beneficial cardiac growth. Science (2011) 1.30
Cancer causes cardiac atrophy and autophagy in a sexually dimorphic manner. Cancer Res (2010) 1.30
Role of myosin heavy chain composition in the stretch activation response of rat myocardium. J Physiol (2006) 1.29
Soy diet worsens heart disease in mice. J Clin Invest (2006) 1.29
History-dependent mechanical properties of permeabilized rat soleus muscle fibers. Biophys J (2002) 1.29
Myosin binding protein C interaction with actin: characterization and mapping of the binding site. J Biol Chem (2010) 1.27
Loaded wheel running and muscle adaptation in the mouse. Am J Physiol Heart Circ Physiol (2005) 1.23
Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway. Proc Natl Acad Sci U S A (2013) 1.20
Mutation that dramatically alters rat titin isoform expression and cardiomyocyte passive tension. J Mol Cell Cardiol (2008) 1.20
Bioinformatics assessment of beta-myosin mutations reveals myosin's high sensitivity to mutations. Trends Cardiovasc Med (2008) 1.20
Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation (2012) 1.19
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol (2011) 1.19
Sex modifies exercise and cardiac adaptation in mice. Am J Physiol Heart Circ Physiol (2004) 1.18
Titin isoform changes in rat myocardium during development. Mech Dev (2004) 1.18
Functional diversity among a family of human skeletal muscle myosin motors. Proc Natl Acad Sci U S A (2009) 1.18
Intrathecal polymer-based interleukin-10 gene delivery for neuropathic pain. Neuron Glia Biol (2006) 1.18
Statins block calcific nodule formation of valvular interstitial cells by inhibiting alpha-smooth muscle actin expression. Arterioscler Thromb Vasc Biol (2009) 1.16
Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium. J Mol Cell Cardiol (2012) 1.13
Sex-based cardiac physiology. Annu Rev Physiol (2009) 1.13
Pregnancy as a cardiac stress model. Cardiovasc Res (2014) 1.11
Expression of Dp260 in muscle tethers the actin cytoskeleton to the dystrophin-glycoprotein complex and partially prevents dystrophy. Hum Mol Genet (2002) 1.10
Protein kinase A-induced myofilament desensitization to Ca(2+) as a result of phosphorylation of cardiac myosin-binding protein C. J Gen Physiol (2010) 1.10
Developmental changes in rat cardiac titin/connectin: transitions in normal animals and in mutants with a delayed pattern of isoform transition. J Muscle Res Cell Motil (2005) 1.09
MyoD, Myf5, and the calcineurin pathway activate the developmental myosin heavy chain genes. Dev Biol (2006) 1.09
The effects of biological sex and diet on the development of heart failure. Circulation (2007) 1.07
Intracellular calcium and myosin isoform transitions. Calcineurin and calcium-calmodulin kinase pathways regulate preferential activation of the IIa myosin heavy chain promoter. J Biol Chem (2002) 1.07
Identification of functional differences between recombinant human α and β cardiac myosin motors. Cell Mol Life Sci (2012) 1.06
Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. Am J Physiol Heart Circ Physiol (2007) 1.06
Myosin light chain 2 into the mainstream of cardiac development and contractility. Circ Res (2006) 1.05
Integrin-linked kinase production prevents anoikis in human mesenchymal stem cells. J Biomed Mater Res A (2007) 1.05
Skeletal myosin heavy chain function in cultured lung myofibroblasts. J Cell Biol (2003) 1.05
Frank-Starling relationship: long on importance, short on mechanism. Circ Res (2002) 1.04
Transmural variation in myosin heavy chain isoform expression modulates the timing of myocardial force generation in porcine left ventricle. J Physiol (2008) 1.03
Cooperativity in the regulation of force and the kinetics of force development in heart and skeletal muscles: cross-bridge activation of force. Adv Exp Med Biol (2007) 1.03