Published in Proc Natl Acad Sci U S A on June 16, 2009
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Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa. Anal Chem (2012) 0.97
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Middle-down mass spectrometry enables characterization of branched ubiquitin chains. Biochemistry (2014) 0.92
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Revealing ligand binding sites and quantifying subunit variants of noncovalent protein complexes in a single native top-down FTICR MS experiment. J Am Soc Mass Spectrom (2014) 0.90
In-depth proteomic analysis of human tropomyosin by top-down mass spectrometry. J Muscle Res Cell Motil (2013) 0.89
High mass selectivity for top-down proteomics by application of SWIFT technology. J Am Soc Mass Spectrom (2009) 0.89
Native top-down electrospray ionization-mass spectrometry of 158 kDa protein complex by high-resolution Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem (2013) 0.88
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New protein footprinting: fast photochemical iodination combined with top-down and bottom-up mass spectrometry. J Am Soc Mass Spectrom (2012) 0.86
High-definition de novo sequencing of crustacean hyperglycemic hormone (CHH)-family neuropeptides. Mol Cell Proteomics (2012) 0.86
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Increased protein structural resolution from diethylpyrocarbonate-based covalent labeling and mass spectrometric detection. J Am Soc Mass Spectrom (2012) 0.83
Surviving the infarct: A profile of cardiac myosin binding protein-C pathogenicity, diagnostic utility, and proteomics in the ischemic myocardium. Proteomics Clin Appl (2014) 0.82
Ultrahigh pressure fast size exclusion chromatography for top-down proteomics. Proteomics (2013) 0.82
Effective enrichment and mass spectrometry analysis of phosphopeptides using mesoporous metal oxide nanomaterials. Anal Chem (2010) 0.82
Proteomics in heart failure: top-down or bottom-up? Pflugers Arch (2014) 0.81
Top-down mass spectrometry of cardiac myofilament proteins in health and disease. Proteomics Clin Appl (2014) 0.81
High throughput screening of disulfide-containing proteins in a complex mixture. Proteomics (2013) 0.81
COOH-terminal truncation of flightin decreases myofilament lattice organization, cross-bridge binding, and power output in Drosophila indirect flight muscle. Am J Physiol Cell Physiol (2011) 0.81
Effective top-down LC/MS+ method for assessing actin isoforms as a potential cardiac disease marker. Anal Chem (2015) 0.81
Online Hydrophobic Interaction Chromatography-Mass Spectrometry for Top-Down Proteomics. Anal Chem (2016) 0.81
The impact of antibody selection on the detection of cardiac troponin I. Clin Chim Acta (2012) 0.80
Limited proteolysis via millisecond digestions in protease-modified membranes. Anal Chem (2012) 0.79
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Mechanism of action of thalassospiramides, a new class of calpain inhibitors. Sci Rep (2015) 0.77
Cross-species mechanical fingerprinting of cardiac myosin binding protein-C. Biophys J (2013) 0.77
Dissecting human skeletal muscle troponin proteoforms by top-down mass spectrometry. J Muscle Res Cell Motil (2015) 0.77
Radical-directed dissociation of peptides and proteins by infrared multiphoton dissociation and sustained off-resonance irradiation collision-induced dissociation with Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom (2014) 0.77
Comprehensive Characterization of AMP-Activated Protein Kinase Catalytic Domain by Top-Down Mass Spectrometry. J Am Soc Mass Spectrom (2016) 0.77
Phosphoproteomics with Activated Ion Electron Transfer Dissociation. Anal Chem (2017) 0.77
Comprehensive analysis of tropomyosin isoforms in skeletal muscles by top-down proteomics. J Muscle Res Cell Motil (2016) 0.76
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Top-Down Targeted Proteomics Reveals Decrease in Myosin Regulatory Light-Chain Phosphorylation That Contributes to Sarcopenic Muscle Dysfunction. J Proteome Res (2016) 0.75
Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. J Mol Cell Cardiol (2017) 0.75
The Impact of Phosphorylation on Electron Capture Dissociation of Proteins: A Top-Down Perspective. J Am Soc Mass Spectrom (2017) 0.75
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Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry. J Biol Chem (2008) 2.28
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Top-down ESI-ECD-FT-ICR mass spectrometry localizes noncovalent protein-ligand binding sites. J Am Chem Soc (2006) 1.68
Myosin binding protein C is differentially phosphorylated upon myocardial stunning in canine and rat hearts-- evidence for novel phosphorylation sites. Proteomics (2006) 1.65
Protein kinase A-mediated phosphorylation of cMyBP-C increases proximity of myosin heads to actin in resting myocardium. Circ Res (2008) 1.55
Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry. J Am Soc Mass Spectrom (2003) 1.41
Characterization of a new qQq-FTICR mass spectrometer for post-translational modification analysis and top-down tandem mass spectrometry of whole proteins. J Am Soc Mass Spectrom (2005) 1.41
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Stepwise deamidation of ribonuclease A at five sites determined by top down mass spectrometry. Biochemistry (2006) 1.28
A new approach for plant proteomics: characterization of chloroplast proteins of Arabidopsis thaliana by top-down mass spectrometry. Mol Cell Proteomics (2003) 1.24
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Detection of four oxidation sites in viral prolyl-4-hydroxylase by top-down mass spectrometry. Protein Sci (2003) 1.13
Detecting deamidation products in proteins by electron capture dissociation. Anal Chem (2006) 1.12
Crystal structure of the C1 domain of cardiac myosin binding protein-C: implications for hypertrophic cardiomyopathy. J Mol Biol (2008) 1.01
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Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure. J Proteome Res (2011) 2.17
Differential roles of cardiac myosin-binding protein C and cardiac troponin I in the myofibrillar force responses to protein kinase A phosphorylation. Circ Res (2007) 2.11
Ablation of cardiac myosin-binding protein-C accelerates stretch activation in murine skinned myocardium. Circ Res (2006) 2.10
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Ablation of myosin-binding protein-C accelerates force development in mouse myocardium. Biophys J (2006) 1.69
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Myosin light chain phosphorylation is critical for adaptation to cardiac stress. Circulation (2012) 1.19
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Top-down targeted proteomics for deep sequencing of tropomyosin isoforms. J Proteome Res (2012) 1.07
Myosin light chain 2 into the mainstream of cardiac development and contractility. Circ Res (2006) 1.05
Discovery and optimization of a series of quinazolinone-derived antagonists of CXCR3. Bioorg Med Chem Lett (2007) 1.04
Frank-Starling relationship: long on importance, short on mechanism. Circ Res (2002) 1.04
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Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium. Am J Physiol Heart Circ Physiol (2004) 0.97
Delineating Anopheles gambiae coactivator associated arginine methyltransferase 1 automethylation using top-down high resolution tandem mass spectrometry. Protein Sci (2009) 0.96
Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles. Am J Physiol Heart Circ Physiol (2011) 0.96
Cycling cross-bridges increase myocardial stiffness at submaximal levels of Ca2+ activation. Biophys J (2003) 0.95
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Phosphorylation, but not alternative splicing or proteolytic degradation, is conserved in human and mouse cardiac troponin T. Biochemistry (2011) 0.90
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Mesoporous zirconium oxide nanomaterials effectively enrich phosphopeptides for mass spectrometry-based phosphoproteomics. Chem Commun (Camb) (2009) 0.84
Resolving myoarchitectural disarray in the mouse ventricular wall with diffusion spectrum magnetic resonance imaging. Ann Biomed Eng (2010) 0.84
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Intramolecular interactions in the N-domain of cardiac troponin C are important determinants of calcium sensitivity of force development. Biochemistry (2008) 0.82
Effective enrichment and mass spectrometry analysis of phosphopeptides using mesoporous metal oxide nanomaterials. Anal Chem (2010) 0.82
The impact of antibody selection on the detection of cardiac troponin I. Clin Chim Acta (2012) 0.80
Nitroxyl, redox switches, cardiac myofilaments, and heart failure: a prequel to novel therapeutics? Circ Res (2012) 0.78
Dissecting human skeletal muscle troponin proteoforms by top-down mass spectrometry. J Muscle Res Cell Motil (2015) 0.77
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