Self-organization of intracellular gradients during mitosis.

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Published in Cell Div on January 29, 2010

Authors

Brian G Fuller1

Author Affiliations

1: Department of Biochemistry and Molecular Genetics, University of Virginia, School of Medicine, Charlottesville, Virginia, 22908, USA. bgf4b@virginia.edu.

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Mechanisms of mitotic spindle assembly and function. Int Rev Cytol (2008) 3.44

Spatial coordination of spindle assembly by chromosome-mediated signaling gradients. Science (2005) 3.38

Midzone microtubule bundles are continuously required for cytokinesis in cultured epithelial cells. J Cell Biol (1996) 3.36

Mechanisms and molecules of the mitotic spindle. Curr Biol (2004) 3.25

A spatial gradient coordinates cell size and mitotic entry in fission yeast. Nature (2009) 3.23

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AIR-2: An Aurora/Ipl1-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos. J Cell Biol (1998) 3.07

Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94

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Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity. Proc Natl Acad Sci U S A (2005) 1.34

Influence of M-phase chromatin on the anisotropy of microtubule asters. J Cell Biol (1996) 1.33

Phosphorylation regulates the dynamic interaction of RCC1 with chromosomes during mitosis. Curr Biol (2004) 1.30

How to get ahead: the origin, evolution and function of bicoid. Bioessays (2005) 1.24

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