PubRank

Paolo Arosio

Author PubWeight™ 83.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J Clin Invest 2013 1.73
2 The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proc Natl Acad Sci U S A 2004 1.59
3 Mitochondrial ferritin expression in erythroid cells from patients with sideroblastic anemia. Blood 2002 1.49
4 RNA silencing of the mitochondrial ABCB7 transporter in HeLa cells causes an iron-deficient phenotype with mitochondrial iron overload. Blood 2006 1.38
5 Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. Blood 2007 1.36
6 Genetic hyperferritinaemia and reticuloendothelial iron overload associated with a three base pair deletion in the coding region of the ferroportin gene (SLC11A3). Br J Haematol 2002 1.32
7 Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol Dis 2003 1.29
8 Multiple pathways for mineral core formation in mammalian apoferritin. The role of hydrogen peroxide. Biochemistry 2003 1.26
9 The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation. J Am Chem Soc 2014 1.22
10 Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism. J Biol Chem 2002 1.22
11 Mitochondrial ferritin. Int J Biochem Cell Biol 2004 1.21
12 New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity. J Autoimmun 2008 1.21
13 Heparin: a potent inhibitor of hepcidin expression in vitro and in vivo. Blood 2010 1.20
14 Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin. Blood 2003 1.20
15 Unique iron binding and oxidation properties of human mitochondrial ferritin: a comparative analysis with Human H-chain ferritin. J Mol Biol 2005 1.20
16 The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast. Hum Mol Genet 2004 1.19
17 Mitochondrial ferritin expression in adult mouse tissues. J Histochem Cytochem 2007 1.17
18 Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells. Hepatology 2009 1.15
19 Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload. Clin Chem 2003 1.15
20 Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala. J Mol Biol 2004 1.15
21 Ferrous ion binding to recombinant human H-chain ferritin. An isothermal titration calorimetry study. Biochemistry 2002 1.12
22 mu-1,2-Peroxobridged di-iron(III) dimer formation in human H-chain ferritin. Biochem J 2002 1.11
23 Neuroferritinopathy: a neurodegenerative disorder associated with L-ferritin mutation. Best Pract Res Clin Haematol 2005 1.11
24 Water-dispersible sugar-coated iron oxide nanoparticles. An evaluation of their relaxometric and magnetic hyperthermia properties. J Am Chem Soc 2011 1.09
25 Biofortification for combating 'hidden hunger' for iron. Trends Plant Sci 2011 1.07
26 Relative contribution of iron genes, dysmetabolism and hepatitis C virus (HCV) in the pathogenesis of altered iron regulation in HCV chronic hepatitis. Haematologica 2007 1.06
27 Design of water-based ferrofluids as contrast agents for magnetic resonance imaging. J Colloid Interface Sci 2011 1.06
28 Ferritin ferroxidase activity: a potent inhibitor of osteogenesis. J Bone Miner Res 2010 1.03
29 Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo. Blood 2014 1.03
30 Ferritin as an important player in neurodegeneration. Parkinsonism Relat Disord 2011 1.03
31 Dysregulation of iron homeostasis in the CNS contributes to disease progression in a mouse model of amyotrophic lateral sclerosis. J Neurosci 2009 1.03
32 The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin. Biochim Biophys Acta 2007 0.99
33 Origin of the unusual kinetics of iron deposition in human H-chain ferritin. J Am Chem Soc 2005 0.99
34 Chemical-physical changes in cell membrane microdomains of breast cancer cells after omega-3 PUFA incorporation. Cell Biochem Biophys 2012 0.99
35 Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells. Blood 2002 0.99
36 Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma. Clin Cancer Res 2003 0.99
37 Structural description of the active sites of mouse L-chain ferritin at 1.2 A resolution. J Biol Inorg Chem 2002 0.97
38 Microelectronic DNA chip for hereditary hyperferritinemia cataract syndrome, a model for large-scale analysis of disorders of iron metabolism. Hum Mutat 2006 0.97
39 Mitochondrial ferritin in the substantia nigra in restless legs syndrome. J Neuropathol Exp Neurol 2009 0.97
40 Identification of new mutations of hepcidin and hemojuvelin in patients with HFE C282Y allele. Blood Cells Mol Dis 2004 0.96
41 Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation. Haematologica 2010 0.96
42 Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy. Neurobiol Dis 2009 0.94
43 Scanning mutations of the 5'UTR regulatory sequence of L-ferritin by denaturing high-performance liquid chromatography: identification of new mutations. Br J Haematol 2003 0.94
44 Pantothenate kinase-2 (Pank2) silencing causes cell growth reduction, cell-specific ferroportin upregulation and iron deregulation. Neurobiol Dis 2010 0.92
45 Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J Biol Chem 2010 0.92
46 ELISA reveals a difference in the structure of substantia nigra ferritin in Parkinson's disease and incidental Lewy body compared to control. Parkinsonism Relat Disord 2007 0.91
47 Ferritin prevents calcification and osteoblastic differentiation of vascular smooth muscle cells. J Am Soc Nephrol 2009 0.90
48 Fusion of the antiferritin antibody VL domain to barnase results in enhanced solubility and altered pH stability. Protein Eng Des Sel 2004 0.90
49 The putative "nucleation site" in human H-chain ferritin is not required for mineralization of the iron core. Biochemistry 2004 0.89
50 Facilitated diffusion of iron(II) and dioxygen substrates into human H-chain ferritin. A fluorescence and absorbance study employing the ferroxidase center substitution Y34W. J Am Chem Soc 2008 0.89
51 Analysis of ferritin genes in Parkinson disease. Clin Chem Lab Med 2007 0.89
52 Role of iron and ferritin in TNFalpha-induced apoptosis in HeLa cells. FEBS Lett 2003 0.88
53 Iron(II) and hydrogen peroxide detoxification by human H-chain ferritin. An EPR spin-trapping study. Biochemistry 2006 0.87
54 New TFR2 mutations in young Italian patients with hemochromatosis. Haematologica 2008 0.87
55 The sedimentation properties of ferritins. New insights and analysis of methods of nanoparticle preparation. Biochim Biophys Acta 2010 0.87
56 Correlation between the bone density recorded by a computerized implant motor and by a histomorphometric analysis: a preliminary in vitro study on bovine ribs. Clin Implant Dent Relat Res 2013 0.86
57 Identification of two novel mutations in the 5'-untranslated region of H-ferritin using denaturing high performance liquid chromatography scanning. Haematologica 2003 0.86
58 Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder. Neurobiol Dis 2006 0.86
59 Ferritin--a mediator of apoptosis? J Cell Physiol 2007 0.85
60 Comparative study between Hfe-/- and beta2m-/- mice: progression with age of iron status and liver pathology. Int J Exp Pathol 2006 0.85
61 Defining metal ion inhibitor interactions with recombinant human H- and L-chain ferritins and site-directed variants: an isothermal titration calorimetry study. J Biol Inorg Chem 2003 0.85
62 HFE gene mutations in a population of Italian Parkinson's disease patients. Parkinsonism Relat Disord 2008 0.84
63 Mice lacking mitochondrial ferritin are more sensitive to doxorubicin-mediated cardiotoxicity. J Mol Med (Berl) 2014 0.84
64 Mutations of ferritin H chain C-terminus produced by nucleotide insertions have altered stability and functional properties. J Biochem 2006 0.84
65 Ferroportin gene silencing induces iron retention and enhances ferritin synthesis in human macrophages. Br J Haematol 2004 0.84
66 Blotting analysis of native IRP1: a novel approach to distinguish the different forms of IRP1 in cells and tissues. Biochemistry 2004 0.84
67 Characterization of the H- and L-subunit ratios of ferritins by sodium dodecyl sulfate-capillary gel electrophoresis. Anal Biochem 2002 0.82
68 Recombinant human hepcidin expressed in Escherichia coli isolates as an iron containing protein. Blood Cells Mol Dis 2005 0.82
69 Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration. Arch Toxicol 2014 0.81
70 Inhibition of heme synthesis alters Amyloid Precursor Protein processing. J Neural Transm (Vienna) 2008 0.81
71 Analysis of nucleotide variations in genes of iron management in patients of Parkinson's disease and other movement disorders. Parkinsons Dis 2010 0.81
72 Kinetic studies of iron deposition catalyzed by recombinant human liver heavy and light ferritins and Azotobacter vinelandii bacterioferritin using O2 and H2O2 as oxidants. Biophys Chem 2005 0.81
73 A novel deletion of the L-ferritin iron-responsive element responsible for severe hereditary hyperferritinaemia-cataract syndrome. Br J Haematol 2002 0.80
74 Coexistence of plasmonic and magnetic properties in Au89Fe11 nanoalloys. Nanoscale 2013 0.80
75 Sequence variations in mitochondrial ferritin: distribution in healthy controls and different types of patients. Genet Test Mol Biomarkers 2010 0.80
76 Iron release from ferritin by flavin nucleotides. Biochim Biophys Acta 2013 0.79
77 Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology. Chem Soc Rev 2017 0.78
78 A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution. Phys Chem Chem Phys 2015 0.77
79 Kinetic analysis of the multistep aggregation mechanism of monoclonal antibodies. J Phys Chem B 2014 0.77
80 No evidence of relation between peripheral neuropathy and presence of hemochromatosis gene mutations in HIV-1-positive patients. J Acquir Immune Defic Syndr 2007 0.77
81 Denaturing HPLC analysis of DNA deletions and insertions. Hum Mutat 2003 0.77
82 A comparative Mössbauer study of the mineral cores of human H-chain ferritin employing dioxygen and hydrogen peroxide as iron oxidants. Biophys Chem 2007 0.77
83 Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates. Chem Commun (Camb) 2015 0.76
84 Role of cosolutes in the aggregation kinetics of monoclonal antibodies. J Phys Chem B 2014 0.76
85 Regional and cellular distribution of mitochondrial ferritin in the mouse brain. J Neurosci Res 2010 0.76
86 Magnetic and relaxation properties of multifunctional polymer-based nanostructured bioferrofluids as MRI contrast agents. Magn Reson Med 2011 0.76
87 Stability and gelation behavior of bovine serum albumin pre-aggregates in the presence of calcium chloride. Phys Chem Chem Phys 2012 0.76
88 Superparamagnetic iron oxide nanoparticles stabilized by a poly(amidoamine)-rhenium complex as potential theranostic probe. Dalton Trans 2013 0.75
89 A multiscale view of therapeutic protein aggregation: a colloid science perspective. Biotechnol J 2015 0.75
90 Chemically and biologically harmless versus harmful ferritin/copper-metallothionein couples. Chemistry 2014 0.75
91 Photoacoustic molecular imaging for in vivo liver iron quantitation. J Biomed Opt 2016 0.75
92 Effect of surfactants on shear-induced gelation and gel morphology of soft strawberry-like particles. Langmuir 2011 0.75
93 A Molecular Logic Gate Enables Single-Molecule Imaging and Tracking of Lipids in Intracellular Domains. ACS Chem Biol 2020 0.75
94 Mechanistic Origin of the Combined Effect of Surfaces and Mechanical Agitation on Amyloid Formation. ACS Nano 2017 0.75
95 Correlation Between Bone Density and Instantaneous Torque at Implant Site Preparation: A Validation on Polyurethane Foam Blocks of a Device Assessing Density of Jawbones. Int J Oral Maxillofac Implants 2016 0.75
96 Antiferritin VL homodimer binds human spleen ferritin with high specificity. J Struct Biol 2002 0.75
97 Observing Xenopus laevis oocyte plasma membrane by Atomic Force Microscopy. Methods 2009 0.75
98 Mitochondrial ferritin deficiency reduces male fertility in mice. Reprod Fertil Dev 2017 0.75