|
1
|
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.
|
Immunity
|
2002
|
14.57
|
|
2
|
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation.
|
Dev Cell
|
2005
|
7.64
|
|
3
|
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor.
|
J Cell Biol
|
2002
|
6.20
|
|
4
|
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth.
|
PLoS One
|
2009
|
3.86
|
|
5
|
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature.
|
Nature
|
2005
|
3.44
|
|
6
|
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo.
|
Proc Natl Acad Sci U S A
|
2002
|
3.25
|
|
7
|
Macrophage Wnt7b is critical for kidney repair and regeneration.
|
Proc Natl Acad Sci U S A
|
2010
|
2.87
|
|
8
|
Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation.
|
J Immunol
|
2005
|
2.50
|
|
9
|
Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.
|
Dev Cell
|
2009
|
2.17
|
|
10
|
A direct and melanopsin-dependent fetal light response regulates mouse eye development.
|
Nature
|
2013
|
1.98
|
|
11
|
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
|
Nature
|
2011
|
1.91
|
|
12
|
Wntless functions in mature osteoblasts to regulate bone mass.
|
Proc Natl Acad Sci U S A
|
2012
|
1.85
|
|
13
|
The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm.
|
Dev Biol
|
2005
|
1.74
|
|
14
|
Generation of mice with a conditional null allele for Wntless.
|
Genesis
|
2010
|
1.55
|
|
15
|
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival.
|
Dev Biol
|
2008
|
1.53
|
|
16
|
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1.
|
Proc Natl Acad Sci U S A
|
2013
|
1.51
|
|
17
|
Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch.
|
Development
|
2007
|
1.47
|
|
18
|
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis.
|
Cell Stem Cell
|
2013
|
1.41
|
|
19
|
Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland.
|
Dev Biol
|
2005
|
1.38
|
|
20
|
Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis.
|
Sci Signal
|
2009
|
1.34
|
|
21
|
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled.
|
J Biol Chem
|
2009
|
1.34
|
|
22
|
Metchnikoff's policemen: macrophages in development, homeostasis and regeneration.
|
Trends Mol Med
|
2011
|
1.34
|
|
23
|
pygopus 2 has a crucial, Wnt pathway-independent function in lens induction.
|
Development
|
2007
|
1.33
|
|
24
|
Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development.
|
BMC Biol
|
2007
|
1.33
|
|
25
|
Bmp signaling is required for development of primary lens fiber cells.
|
Development
|
2002
|
1.33
|
|
26
|
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation.
|
Proc Natl Acad Sci U S A
|
2011
|
1.26
|
|
27
|
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia.
|
Proc Natl Acad Sci U S A
|
2011
|
1.25
|
|
28
|
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts.
|
J Biol Chem
|
2011
|
1.23
|
|
29
|
Resident pleural macrophages are key orchestrators of neutrophil recruitment in pleural inflammation.
|
Am J Respir Crit Care Med
|
2005
|
1.22
|
|
30
|
Stage-dependent modes of Pax6-Sox2 epistasis regulate lens development and eye morphogenesis.
|
Development
|
2009
|
1.22
|
|
31
|
Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation.
|
Development
|
2010
|
1.22
|
|
32
|
Pax6-dependent Shroom3 expression regulates apical constriction during lens placode invagination.
|
Development
|
2010
|
1.15
|
|
33
|
Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination.
|
Development
|
2009
|
1.14
|
|
34
|
Bmp7 regulates branching morphogenesis of the lacrimal gland by promoting mesenchymal proliferation and condensation.
|
Development
|
2004
|
1.14
|
|
35
|
RhoA protects the mouse heart against ischemia/reperfusion injury.
|
J Clin Invest
|
2011
|
1.12
|
|
36
|
Pax6 is essential for lens fiber cell differentiation.
|
Development
|
2009
|
1.12
|
|
37
|
β-catenin signaling in murine liver zonation and regeneration: a Wnt-Wnt situation!
|
Hepatology
|
2014
|
1.09
|
|
38
|
A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination.
|
Development
|
2011
|
1.07
|
|
39
|
Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis.
|
Dev Biol
|
2011
|
1.03
|
|
40
|
Optic cup and facial patterning defects in ocular ectoderm beta-catenin gain-of-function mice.
|
BMC Dev Biol
|
2006
|
0.98
|
|
41
|
Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes.
|
Development
|
2013
|
0.95
|
|
42
|
Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure.
|
Proc Natl Acad Sci U S A
|
2011
|
0.94
|
|
43
|
Eye formation in the absence of retina.
|
Dev Biol
|
2008
|
0.90
|
|
44
|
Macrophage Wnt-Calcineurin-Flt1 signaling regulates mouse wound angiogenesis and repair.
|
Blood
|
2013
|
0.90
|
|
45
|
RhoA of the Rho family small GTPases is essential for B lymphocyte development.
|
PLoS One
|
2012
|
0.89
|
|
46
|
Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
|
Development
|
2013
|
0.89
|
|
47
|
Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.
|
Dev Biol
|
2011
|
0.88
|
|
48
|
RhoA is dispensable for axon guidance of sensory neurons in the mouse dorsal root ganglia.
|
Front Mol Neurosci
|
2012
|
0.88
|
|
49
|
Wnt2 regulates progenitor proliferation in the developing ventral midbrain.
|
J Biol Chem
|
2009
|
0.87
|
|
50
|
Left-right locomotor circuitry depends on RhoA-driven organization of the neuroepithelium in the developing spinal cord.
|
J Neurosci
|
2012
|
0.85
|
|
51
|
The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone.
|
PLoS One
|
2012
|
0.84
|
|
52
|
CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis.
|
PLoS One
|
2012
|
0.83
|
|
53
|
Which FGF ligands are involved in lens induction?
|
Dev Biol
|
2009
|
0.81
|
|
54
|
RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration.
|
Development
|
2013
|
0.80
|
|
55
|
Length of day during early gestation as a predictor of risk for severe retinopathy of prematurity.
|
Ophthalmology
|
2013
|
0.79
|
|
56
|
Generation of an Rx-tTA: TetOp-Cre knock-in mouse line for doxycycline regulated Cre activity in the Rx expression domain.
|
PLoS One
|
2012
|
0.76
|
|
57
|
Digesta retention patterns of solute and different-sized particles in camelids compared with ruminants and other foregut fermenters.
|
J Comp Physiol B
|
2015
|
0.75
|