Published in J Neurosci on July 25, 2012
Cell type-specific signaling function of RhoA GTPase: lessons from mouse gene targeting. J Biol Chem (2013) 0.93
RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration. Development (2013) 0.80
Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons. PLoS One (2013) 0.80
Rho GTPases in embryonic development. Small GTPases (2014) 0.79
The small GTPase RhoA is required for proper locomotor circuit assembly. PLoS One (2013) 0.78
Synapse Formation in Monosynaptic Sensory-Motor Connections Is Regulated by Presynaptic Rho GTPase Cdc42. J Neurosci (2016) 0.76
Association of ARHGAP18 polymorphisms with schizophrenia in the Chinese-Han population. PLoS One (2017) 0.75
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol (1998) 10.58
Directed differentiation of embryonic stem cells into motor neurons. Cell (2002) 9.76
Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat Rev Genet (2000) 9.54
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes. Cell (1994) 5.64
Descending pathways in motor control. Annu Rev Neurosci (2008) 4.29
Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab (2011) 3.68
Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism. Nature (2007) 2.97
Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1. Cell (2008) 2.60
Neural crest cells retain multipotential characteristics in the developing valves and label the cardiac conduction system. Circ Res (2006) 2.59
LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell (1998) 2.50
Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons. Neuron (2008) 2.44
Hox networks and the origins of motor neuron diversity. Curr Top Dev Biol (2009) 2.30
Role of EphA4 and EphrinB3 in local neuronal circuits that control walking. Science (2003) 2.20
Transcriptional networks regulating neuronal identity in the developing spinal cord. Nat Neurosci (2001) 1.99
Brn-3.0 expression identifies early post-mitotic CNS neurons and sensory neural precursors. Mech Dev (1995) 1.92
EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract. Proc Natl Acad Sci U S A (1998) 1.91
Ephrin-B3 is the midline barrier that prevents corticospinal tract axons from recrossing, allowing for unilateral motor control. Genes Dev (2001) 1.83
Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling. Cell (2007) 1.82
Forward signaling mediated by ephrin-B3 prevents contralateral corticospinal axons from recrossing the spinal cord midline. Neuron (2001) 1.64
Adhesive and signaling functions of cadherins and catenins in vertebrate development. Cold Spring Harb Perspect Biol (2009) 1.52
Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional template. Cell (2011) 1.51
alpha2-Chimaerin is an essential EphA4 effector in the assembly of neuronal locomotor circuits. Neuron (2007) 1.49
Diverse roles of Rho family GTPases in neuronal development, survival, and death. Front Biosci (2008) 1.49
EphA4-dependent axon guidance is mediated by the RacGAP alpha2-chimaerin. Neuron (2007) 1.48
Patterning cell types in the dorsal spinal cord: what the mouse mutants say. Nat Rev Neurosci (2003) 1.46
Nck adaptor proteins control the organization of neuronal circuits important for walking. Proc Natl Acad Sci U S A (2007) 1.33
Rho GTPases and their regulators in neuronal functions and development. Neurosignals (2007) 1.30
Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc Natl Acad Sci U S A (2011) 1.26
Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A (2011) 1.25
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts. J Biol Chem (2011) 1.23
A radial glia-specific role of RhoA in double cortex formation. Neuron (2012) 1.21
Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci (2004) 1.21
Mir-17-3p controls spinal neural progenitor patterning by regulating Olig2/Irx3 cross-repressive loop. Neuron (2011) 1.20
Central pattern generators deciphered by molecular genetics. Neuron (2004) 1.09
Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons. Development (2000) 1.08
Molecular mechanisms of axon guidance in the developing corticospinal tract. Prog Neurobiol (2008) 1.06
The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool. J Neurosci (2011) 1.03
Postnatal growth of corticospinal axons in the spinal cord of developing mice. Brain Res Dev Brain Res (1999) 1.02
Regional- and temporal-dependent changes in the differentiation of Olig2 progenitors in the forebrain, and the impact on astrocyte development in the dorsal pallium. Dev Biol (2008) 1.01
Manipulating gene activity in Wnt1-expressing precursors of neural epithelial and neural crest cells. Dev Dyn (2010) 0.99
Ectopic myelinating oligodendrocytes in the dorsal spinal cord as a consequence of altered semaphorin 6D signaling inhibit synapse formation. Development (2011) 0.96
Change in the balance of excitatory and inhibitory midline fiber crossing as an explanation for the hopping phenotype in EphA4 knockout mice. Eur J Neurosci (2011) 0.83
Corticospinal tract fibers cross the ephrin-B3-negative part of the midline of the spinal cord after brain injury. Neurosci Res (2010) 0.83
Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons. Eur J Neurosci (2011) 0.77
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Roll-to-roll production of 30-inch graphene films for transparent electrodes. Nat Nanotechnol (2010) 12.59
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell (2005) 7.64
Rational design and characterization of a Rac GTPase-specific small molecule inhibitor. Proc Natl Acad Sci U S A (2004) 7.24
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor. J Cell Biol (2002) 6.20
A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One (2009) 3.86
Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia. Cancer Cell (2008) 3.79
WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature. Nature (2005) 3.44
Rho GTPase-activating proteins in cell regulation. Trends Cell Biol (2003) 3.44
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci U S A (2002) 3.25
Shearwave dispersion ultrasound vibrometry (SDUV) for measuring tissue elasticity and viscosity. IEEE Trans Ultrason Ferroelectr Freq Control (2009) 3.00
Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins. Science (2004) 2.95
Compact biocompatible quantum dots functionalized for cellular imaging. J Am Chem Soc (2008) 2.92
Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A (2010) 2.87
High-throughput illumina strand-specific RNA sequencing library preparation. Cold Spring Harb Protoc (2011) 2.72
Monovalent, reduced-size quantum dots for imaging receptors on living cells. Nat Methods (2008) 2.68
Enamines as novel antibacterials and their structure-activity relationships. Eur J Med Chem (2007) 2.65
Anterior pedicle screw fixation of C2: an anatomic analysis of axis morphology and simulated surgical fixation. Eur Spine J (2014) 2.64
Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization. Nat Med (2005) 2.63
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing. Nature (2013) 2.62
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. Cell Stem Cell (2012) 2.60
Conditional macrophage ablation demonstrates that resident macrophages initiate acute peritoneal inflammation. J Immunol (2005) 2.50
A cost-effective method for Illumina small RNA-Seq library preparation using T4 RNA ligase 1 adenylated adapters. Plant Methods (2012) 2.46
Single-base resolution methylomes of tomato fruit development reveal epigenome modifications associated with ripening. Nat Biotechnol (2013) 2.43
The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions. Nat Genet (2012) 2.33
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. Proc Natl Acad Sci U S A (2008) 2.26
Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. Dev Cell (2009) 2.17
A Rac-cGMP signaling pathway. Cell (2007) 2.16
An essential role for Rac1 in endothelial cell function and vascular development. FASEB J (2008) 2.09
Signaling and cytoskeletal requirements in erythroblast enucleation. Blood (2012) 2.05
A direct and melanopsin-dependent fetal light response regulates mouse eye development. Nature (2013) 1.98
Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum. J Neurosci (2008) 1.97
Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. Mol Biol Cell (2006) 1.96
Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease. N Engl J Med (2009) 1.96
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature (2011) 1.91
Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature (2009) 1.88
Transcriptome sequencing and comparative analysis of cucumber flowers with different sex types. BMC Genomics (2010) 1.88
Tissue- and cell-type specific transcriptome profiling of expanding tomato fruit provides insights into metabolic and regulatory specialization and cuticle formation. Plant Cell (2011) 1.88
VKORC1 haplotypes are associated with arterial vascular diseases (stroke, coronary heart disease, and aortic dissection). Circulation (2006) 1.86
Wntless functions in mature osteoblasts to regulate bone mass. Proc Natl Acad Sci U S A (2012) 1.85
Gating of Sema3E/PlexinD1 signaling by neuropilin-1 switches axonal repulsion to attraction during brain development. Neuron (2007) 1.83
Conditional rhythmicity of ventral spinal interneurons defined by expression of the Hb9 homeodomain protein. J Neurosci (2005) 1.76
The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm. Dev Biol (2005) 1.74
Transjugular intrahepatic portosystemic shunt versus endoscopic therapy in the secondary prophylaxis of variceal rebleeding in cirrhotic patients: meta-analysis update. J Clin Gastroenterol (2008) 1.74
Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow. Proc Natl Acad Sci U S A (2007) 1.74
Rac guanosine triphosphatases represent integrating molecular therapeutic targets for BCR-ABL-induced myeloproliferative disease. Cancer Cell (2007) 1.72
Cdc42 regulates bone modeling and remodeling in mice by modulating RANKL/M-CSF signaling and osteoclast polarization. J Clin Invest (2010) 1.71
Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans. Neuron (2002) 1.70
Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly. J Biol Chem (2006) 1.66
Semaphorin 3E-Plexin-D1 signaling regulates VEGF function in developmental angiogenesis via a feedback mechanism. Genes Dev (2011) 1.63
Expression of seven main Rho family members in gastric carcinoma. Biochem Biophys Res Commun (2004) 1.63
Cdc42 coordinates proliferation, polarity, migration, and differentiation of small intestinal epithelial cells in mice. Gastroenterology (2013) 1.62
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. Proc Natl Acad Sci U S A (2013) 1.57
Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils. Nat Immunol (2004) 1.56
Generation of mice with a conditional null allele for Wntless. Genesis (2010) 1.55
miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells. Int J Cancer (2011) 1.53
Sema3A regulates bone-mass accrual through sensory innervations. Nature (2013) 1.53
Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc Natl Acad Sci U S A (2006) 1.53
Co-operative roles for E-cadherin and N-cadherin during lens vesicle separation and lens epithelial cell survival. Dev Biol (2008) 1.53
ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell (2002) 1.53
Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential. Oncogene (2004) 1.52
Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment. Blood (2005) 1.52
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci U S A (2013) 1.51
Rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons. Nat Neurosci (2012) 1.50
Cdc42 in oncogenic transformation, invasion, and tumorigenesis. Cell Signal (2011) 1.50
p19Arf-p53 tumor suppressor pathway regulates cell motility by suppression of phosphoinositide 3-kinase and Rac1 GTPase activities. J Biol Chem (2003) 1.49
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Mol Biol Cell (2003) 1.48
Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch. Development (2007) 1.47
Two distinct roles of mitogen-activated protein kinases in platelets and a novel Rac1-MAPK-dependent integrin outside-in retractile signaling pathway. Blood (2008) 1.47
A role of STAT3 in Rho GTPase-regulated cell migration and proliferation. J Biol Chem (2005) 1.47
Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch (2006) 1.46
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. J Clin Invest (2011) 1.44
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton. Blood (2006) 1.41
Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell (2013) 1.41
Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways. PLoS One (2013) 1.40
The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern. Genome Res (2005) 1.40
Oligo-astheno-teratozoospermia in mice lacking Cnot7, a regulator of retinoid X receptor beta. Nat Genet (2004) 1.40
Cell type-specific functions of Rho GTPases revealed by gene targeting in mice. Trends Cell Biol (2006) 1.39
Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron (2011) 1.39
Safety of infliximab therapy in rheumatoid arthritis patients with previous exposure to hepatitis B virus. Int J Rheum Dis (2013) 1.39
Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland. Dev Biol (2005) 1.38
Rho GTPases in hematopoiesis and hemopathies. Blood (2009) 1.37
Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development. Blood (2008) 1.37
Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation. Genes Dev (2002) 1.36
Electrochemical delamination of CVD-grown graphene film: toward the recyclable use of copper catalyst. ACS Nano (2011) 1.36
A randomized study of transendocardial injection of autologous bone marrow mononuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF). Am Heart J (2011) 1.35
Polymorphisms of KDR gene are associated with coronary heart disease. J Am Coll Cardiol (2007) 1.35
A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells. J Biol Chem (2003) 1.35
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled. J Biol Chem (2009) 1.34
Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis. Sci Signal (2009) 1.34
Rac1 and Rac2 GTPases are necessary for early erythropoietic expansion in the bone marrow but not in the spleen. Haematologica (2010) 1.34
Increased hematopoietic stem cell mobilization in aged mice. Blood (2006) 1.34
Metchnikoff's policemen: macrophages in development, homeostasis and regeneration. Trends Mol Med (2011) 1.34
Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility. Mol Biol Cell (2004) 1.33
pygopus 2 has a crucial, Wnt pathway-independent function in lens induction. Development (2007) 1.33
Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten and microRNA bantam. Genes Dev (2012) 1.33
Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development. BMC Biol (2007) 1.33
Bmp signaling is required for development of primary lens fiber cells. Development (2002) 1.33
Rho GTPases and regulation of hematopoietic stem cell localization. Methods Enzymol (2008) 1.33
Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II. Nat Immunol (2010) 1.33