Published in J Biol Chem on July 29, 2004
Functional anthology of intrinsic disorder. 1. Biological processes and functions of proteins with long disordered regions. J Proteome Res (2007) 2.61
Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen. Infect Immun (2007) 2.12
Fibronectin binding protein BBK32 of the Lyme disease spirochete promotes bacterial attachment to glycosaminoglycans. Infect Immun (2006) 1.55
Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection. Infect Immun (2008) 1.36
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog (2008) 1.34
Borrelia burgdorferi RevA antigen binds host fibronectin. Infect Immun (2009) 1.21
The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin. J Vet Sci (2008) 1.20
Fibronectin binds to and induces conformational change in a disordered region of leptospiral immunoglobulin-like protein B. J Biol Chem (2009) 1.13
Extended binding site on fibronectin for the functional upstream domain of protein F1 of Streptococcus pyogenes. J Biol Chem (2010) 1.11
Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity. Mol Microbiol (2011) 1.08
Vascular binding of a pathogen under shear force through mechanistically distinct sequential interactions with host macromolecules. Mol Microbiol (2012) 1.05
Illuminating the roles of the Borrelia burgdorferi adhesins. Trends Microbiol (2013) 1.03
Structural and functional analysis of the tandem β-zipper interaction of a Streptococcal protein with human fibronectin. J Biol Chem (2011) 0.99
A novel fibronectin binding motif in MSCRAMMs targets F3 modules. PLoS One (2009) 0.92
Invasion of eukaryotic cells by Borrelia burgdorferi requires β(1) integrins and Src kinase activity. Infect Immun (2010) 0.92
That's my story, and I'm sticking to it--an update on B. burgdorferi adhesins. Front Cell Infect Microbiol (2014) 0.91
Glycosaminoglycan binding by Borrelia burgdorferi adhesin BBK32 specifically and uniquely promotes joint colonization. Cell Microbiol (2015) 0.89
Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi. J Bacteriol (2007) 0.89
iso-DGR sequences do not mediate binding of fibronectin N-terminal modules to adherent fibronectin-null fibroblasts. J Biol Chem (2010) 0.87
The group A streptococcal collagen-like protein-1, Scl1, mediates biofilm formation by targeting the extra domain A-containing variant of cellular fibronectin expressed in wounded tissue. Mol Microbiol (2012) 0.86
Borrelia burgdorferi protein BBK32 binds to soluble fibronectin via the N-terminal 70-kDa region, causing fibronectin to undergo conformational extension. J Biol Chem (2014) 0.85
The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions. J Bacteriol (2014) 0.82
Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex. PLoS Pathog (2016) 0.80
The BBA33 lipoprotein binds collagen and impacts Borrelia burgdorferi pathogenesis. Mol Microbiol (2015) 0.80
Borrelia burgdorferi Keeps Moving and Carries on: A Review of Borrelial Dissemination and Invasion. Front Immunol (2017) 0.80
Dynamic structure of plasma fibronectin. Crit Rev Biochem Mol Biol (2016) 0.79
Biomechanics of Borrelia burgdorferi Vascular Interactions. Cell Rep (2016) 0.78
BB0172, a Borrelia burgdorferi outer membrane protein that binds integrin α3β1. J Bacteriol (2013) 0.78
Mapping the ligand-binding region of Borrelia hermsii fibronectin-binding protein. PLoS One (2013) 0.77
Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding Motif. MBio (2016) 0.76
On-Off Kinetics of Engagement of FNI Modules of Soluble Fibronectin by β-Strand Addition. PLoS One (2015) 0.76
Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria. Cell Host Microbe (2017) 0.75
A critical appraisal of "chronic Lyme disease". N Engl J Med (2007) 7.84
Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science (2007) 7.06
Endocarditis and biofilm-associated pili of Enterococcus faecalis. J Clin Invest (2006) 3.33
Serodiagnosis of Lyme disease by kinetic enzyme-linked immunosorbent assay using recombinant VlsE1 or peptide antigens of Borrelia burgdorferi compared with 2-tiered testing using whole-cell lysates. J Infect Dis (2003) 3.18
Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper. Nature (2003) 2.27
Antibody responses to Borrelia burgdorferi in patients with antibiotic-refractory, antibiotic-responsive, or non-antibiotic-treated Lyme arthritis. Arthritis Rheum (2007) 2.20
The molecular basis of fibronectin-mediated bacterial adherence to host cells. Mol Microbiol (2004) 2.20
A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A. EMBO J (2002) 2.06
Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices. J Biol Chem (2002) 1.95
Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi. Mol Microbiol (2006) 1.93
A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen. EMBO J (2005) 1.78
The Scottish Structural Proteomics Facility: targets, methods and outputs. J Struct Funct Genomics (2010) 1.66
A family of putative MSCRAMMs from Enterococcus faecalis. Microbiology (2004) 1.63
The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell-mediated responses. J Clin Invest (2002) 1.63
Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains. Proc Natl Acad Sci U S A (2008) 1.62
Inhibition of complement activation by a secreted Staphylococcus aureus protein. J Infect Dis (2004) 1.62
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol (2004) 1.61
Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin. Proc Natl Acad Sci U S A (2012) 1.56
Identification and characterization of the C3 binding domain of the Staphylococcus aureus extracellular fibrinogen-binding protein (Efb). J Biol Chem (2004) 1.55
A structural model of the Staphylococcus aureus ClfA-fibrinogen interaction opens new avenues for the design of anti-staphylococcal therapeutics. PLoS Pathog (2008) 1.55
Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development (2009) 1.50
Identification and phenotypic characterization of a second collagen adhesin, Scm, and genome-based identification and analysis of 13 other predicted MSCRAMMs, including four distinct pilus loci, in Enterococcus faecium. Microbiology (2008) 1.47
Fibronectin-binding proteins of gram-positive cocci. Microbes Infect (2006) 1.47
Single-tier testing with the C6 peptide ELISA kit compared with two-tier testing for Lyme disease. Diagn Microbiol Infect Dis (2012) 1.45
Role of surface protein SasG in biofilm formation by Staphylococcus aureus. J Bacteriol (2010) 1.40
Identification and preliminary characterization of cell-wall-anchored proteins of Staphylococcus epidermidis. Microbiology (2005) 1.37
Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi. Am J Respir Cell Mol Biol (2009) 1.36
Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection. Infect Immun (2008) 1.36
Virulence potential of the staphylococcal adhesin CNA in experimental arthritis is determined by its affinity for collagen. J Infect Dis (2004) 1.36
A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair Regen (2006) 1.33
The evolution and maintenance of virulence in Staphylococcus aureus: a role for host-to-host transmission? Nat Rev Microbiol (2006) 1.33
The tandem beta-zipper model defines high affinity fibronectin-binding repeats within Staphylococcus aureus FnBPA. J Biol Chem (2007) 1.32
The genome sequence of Lone Star virus, a highly divergent bunyavirus found in the Amblyomma americanum tick. PLoS One (2013) 1.30
Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. J Biol Chem (2007) 1.28
A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling. J Biol Chem (2005) 1.27
Borrelia burgdorferi binds fibronectin through a tandem beta-zipper, a common mechanism of fibronectin binding in staphylococci, streptococci, and spirochetes. J Biol Chem (2005) 1.27
Assessment of prokaryotic collagen-like sequences derived from streptococcal Scl1 and Scl2 proteins as a source of recombinant GXY polymers. Appl Microbiol Biotechnol (2006) 1.26
Staphylococcus aureus host cell invasion and virulence in sepsis is facilitated by the multiple repeats within FnBPA. PLoS Pathog (2010) 1.24
The solution and crystal structures of a module pair from the Staphylococcus aureus-binding site of human fibronectin--a tale with a twist. J Mol Biol (2007) 1.24
Molecular characterization of the interaction of staphylococcal microbial surface components recognizing adhesive matrix molecules (MSCRAMM) ClfA and Fbl with fibrinogen. J Biol Chem (2009) 1.24
Fibrinogen-binding proteins of Gram-positive bacteria. Thromb Haemost (2007) 1.23
MSCRAMM--targeted vaccines and immunotherapy for staphylococcal infection. Curr Opin Drug Discov Devel (2004) 1.21
Scl1-dependent internalization of group A Streptococcus via direct interactions with the alpha2beta(1) integrin enhances pathogen survival and re-emergence. Mol Microbiol (2007) 1.21
The cyanobactin heterocyclase enzyme: a processive adenylase that operates with a defined order of reaction. Angew Chem Int Ed Engl (2013) 1.20
Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis. J Biol Chem (2004) 1.16
Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG. J Biol Chem (2007) 1.16
A novel binding site in collagen type III for integrins alpha1beta1 and alpha2beta1. J Biol Chem (2005) 1.15
2-tiered antibody testing for early and late Lyme disease using only an immunoglobulin G blot with the addition of a VlsE band as the second-tier test. Clin Infect Dis (2010) 1.15
Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Proc Natl Acad Sci U S A (2008) 1.15
The helicase XPD unwinds bubble structures and is not stalled by DNA lesions removed by the nucleotide excision repair pathway. Nucleic Acids Res (2009) 1.14
High affinity streptococcal binding to human fibronectin requires specific recognition of sequential F1 modules. J Biol Chem (2004) 1.14
Identification and biochemical characterization of two novel collagen binding MSCRAMMs of Bacillus anthracis. J Biol Chem (2004) 1.13
The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model. J Biol Chem (2007) 1.13
Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions. J Biol Chem (2011) 1.10
Chondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I. J Bone Miner Res (2002) 1.09
Matricellular hevin regulates decorin production and collagen assembly. J Biol Chem (2006) 1.09
Multicomponent Lyme vaccine: three is not a crowd. Vaccine (2005) 1.09
Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity. Mol Microbiol (2011) 1.08
NMR spectroscopic and theoretical analysis of a spontaneously formed Lys-Asp isopeptide bond. Angew Chem Int Ed Engl (2010) 1.06
Dominant epitopes of the C6 diagnostic peptide of Borrelia burgdorferi are largely inaccessible to antibody on the parent VlsE molecule. Clin Vaccine Immunol (2007) 1.05
Glycerophosphodiester phosphodiesterase gene (glpQ) of Borrelia lonestari identified as a target for differentiating Borrelia species associated with hard ticks (Acari:Ixodidae). J Clin Microbiol (2004) 1.05
beta-Neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC. PLoS Pathog (2010) 1.04
Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway. J Biol Chem (2013) 1.04
Staphylococcal biofilm-forming protein has a contiguous rod-like structure. Proc Natl Acad Sci U S A (2012) 1.04
Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia. Blood (2013) 1.03
Sialic acid mutarotation is catalyzed by the Escherichia coli beta-propeller protein YjhT. J Biol Chem (2007) 1.02
Significant improvement of the recombinant Borrelia-specific immunoglobulin G immunoblot test by addition of VlsE and a DbpA homologue derived from Borrelia garinii for diagnosis of early neuroborreliosis. J Clin Microbiol (2003) 1.02
Decorin-binding sites in the adhesin DbpA from Borrelia burgdorferi: a synthetic peptide approach. J Biol Chem (2003) 1.02
Procollagen C proteinase enhancer 1 genes are important determinants of the mechanical properties and geometry of bone and the ultrastructure of connective tissues. Mol Cell Biol (2006) 1.01
Decorin modulates fibrin assembly and structure. J Biol Chem (2006) 1.01
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest (2010) 1.00
Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence. J Biol Chem (2011) 0.99
An efficient method for the in vitro production of azol(in)e-based cyclic peptides. Angew Chem Int Ed Engl (2014) 0.99
Structural and functional analysis of the tandem β-zipper interaction of a Streptococcal protein with human fibronectin. J Biol Chem (2011) 0.99
Src kinase has a central role in in vitro cellular internalization of Staphylococcus aureus. Cell Microbiol (2003) 0.97
Multiplex immunoassay for Lyme disease using VlsE1-IgG and pepC10-IgM antibodies: improving test performance through bioinformatics. Clin Vaccine Immunol (2011) 0.97
DNA evidence of Borrelia lonestari in Amblyomma americanum (Acari: Ixodidae) in southeast Missouri. J Med Entomol (2003) 0.96
Cooperative binding and activation of fibronectin by a bacterial surface protein. J Biol Chem (2010) 0.95
Staphylococcus aureus keratinocyte invasion is dependent upon multiple high-affinity fibronectin-binding repeats within FnBPA. PLoS One (2011) 0.95
Lyme disease spirochaetes possess an aggrecan-binding protease with aggrecanase activity. Mol Microbiol (2013) 0.94
Entry of Bacillus anthracis spores into epithelial cells is mediated by the spore surface protein BclA, integrin α2β1 and complement component C1q. Cell Microbiol (2010) 0.93
A family of fibrinogen-binding MSCRAMMs from Enterococcus faecalis. Microbiology (2009) 0.93
A novel fibronectin binding motif in MSCRAMMs targets F3 modules. PLoS One (2009) 0.92
Invasion of eukaryotic cells by Borrelia burgdorferi requires β(1) integrins and Src kinase activity. Infect Immun (2010) 0.92
An engineered alpha1 integrin-binding collagenous sequence. J Biol Chem (2010) 0.92