Published in J Infect Dis on July 06, 2004
Complement evasion by human pathogens. Nat Rev Microbiol (2008) 4.24
A Staphylococcus aureus regulatory system that responds to host heme and modulates virulence. Cell Host Microbe (2007) 2.55
The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin Microbiol Infect (2008) 2.14
Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen. Infect Immun (2007) 2.12
Staphylococcal complement evasion by various convertase-blocking molecules. J Exp Med (2007) 2.03
Comparison of antibody repertoires against Staphylococcus aureus in healthy individuals and in acutely infected patients. Clin Diagn Lab Immunol (2005) 1.60
Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci U S A (2010) 1.37
The Staphylococcus aureus protein Sbi acts as a complement inhibitor and forms a tripartite complex with host complement Factor H and C3b. PLoS Pathog (2008) 1.34
Complement System Part II: Role in Immunity. Front Immunol (2015) 1.31
A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family. J Immunol (2009) 1.16
Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interaction. J Bacteriol (2013) 1.15
Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity. Semin Immunopathol (2011) 1.13
Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci (2008) 1.09
Cutting edge: members of the Staphylococcus aureus extracellular fibrinogen-binding protein family inhibit the interaction of C3d with complement receptor 2. J Immunol (2008) 1.07
Phagocytosis escape by a Staphylococcus aureus protein that connects complement and coagulation proteins at the bacterial surface. PLoS Pathog (2013) 1.02
Pediatric antibody response to community-acquired Staphylococcus aureus infection is directed to Panton-Valentine leukocidin. Clin Vaccine Immunol (2008) 1.01
Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence. J Biol Chem (2011) 0.99
Allele-dependent differences in quorum-sensing dynamics result in variant expression of virulence genes in Staphylococcus aureus. J Bacteriol (2012) 0.98
Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b. PLoS One (2012) 0.98
Characterization of Virulence Factors of Staphylococcus aureus: Novel Function of Known Virulence Factors That Are Implicated in Activation of Airway Epithelial Proinflammatory Response. J Pathog (2011) 0.96
Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi. J Biol Chem (2008) 0.96
Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections. Arthritis Res Ther (2006) 0.95
Protease-dependent mechanisms of complement evasion by bacterial pathogens. Biol Chem (2012) 0.94
Multiple activities of LigB potentiate virulence of Leptospira interrogans: inhibition of alternative and classical pathways of complement. PLoS One (2012) 0.91
Humoral innate immune response and disease. Clin Immunol (2012) 0.89
Advances in understanding the structure, function, and mechanism of the SCIN and Efb families of Staphylococcal immune evasion proteins. Adv Exp Med Biol (2012) 0.88
Impact of Staphylococcus aureus on pathogenesis in polymicrobial infections. Infect Immun (2014) 0.88
Host airway proteins interact with Staphylococcus aureus during early pneumonia. Infect Immun (2008) 0.87
Impaired function of antibodies to pneumococcal surface protein A but not to capsular polysaccharide in Mexican American adults with type 2 diabetes mellitus. Clin Vaccine Immunol (2012) 0.82
Activation of the classical complement pathway by Bacillus anthracis is the primary mechanism for spore phagocytosis and involves the spore surface protein BclA. J Immunol (2012) 0.82
A scabies mite serpin interferes with complement-mediated neutrophil functions and promotes staphylococcal growth. PLoS Negl Trop Dis (2014) 0.81
Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes. J Bacteriol (2007) 0.81
The production of extracellular proteins is regulated by ribonuclease III via two different pathways in Staphylococcus aureus. PLoS One (2011) 0.81
The Immunology of Mammary Gland of Dairy Ruminants between Healthy and Inflammatory Conditions. J Vet Med (2014) 0.81
Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement Complex. PLoS Pathog (2016) 0.80
Novel Evasion Mechanisms of the Classical Complement Pathway. J Immunol (2016) 0.80
Biomimetic strategies based on viruses and bacteria for the development of immune evasive biomaterials. Biomaterials (2009) 0.79
The Group B Streptococcus-Secreted Protein CIP Interacts with C4, Preventing C3b Deposition via the Lectin and Classical Complement Pathways. J Immunol (2015) 0.79
Constitutive production of catalytic antibodies to a Staphylococcus aureus virulence factor and effect of infection. J Biol Chem (2012) 0.78
Crystallization and X-ray diffraction analysis of the complement component-3 (C3) inhibitory domain of Efb from Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.76
Staphylococcus aureus Aggregation and Coagulation Mechanisms, and Their Function in Host-Pathogen Interactions. Adv Appl Microbiol (2016) 0.75
Fibrinogen Is at the Interface of Host Defense and Pathogen Virulence in Staphylococcus aureus Infection. Semin Thromb Hemost (2016) 0.75
A rapid method for selecting suitable animal species for studying pathogen interactions with plasma protein ligands in vivo. Microb Biotechnol (2017) 0.75
Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes. J Biol Chem (2015) 0.75
Let's Tie the Knot: Marriage of Complement and Adaptive Immunity in Pathogen Evasion, for Better or Worse. Front Microbiol (2017) 0.75
Neutrophils and Immunity: From Bactericidal Action to Being Conquered. J Immunol Res (2017) 0.75
Epic Immune Battles of History: Neutrophils vs. Staphylococcus aureus. Front Cell Infect Microbiol (2017) 0.75
Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science (2007) 7.06
Generation of C5a in the absence of C3: a new complement activation pathway. Nat Med (2006) 5.26
Endocarditis and biofilm-associated pili of Enterococcus faecalis. J Clin Invest (2006) 3.33
Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. Blood (2007) 2.72
Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest (2003) 2.39
Pathogenic bacteria attach to human fibronectin through a tandem beta-zipper. Nature (2003) 2.27
The molecular basis of fibronectin-mediated bacterial adherence to host cells. Mol Microbiol (2004) 2.20
A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A. EMBO J (2002) 2.06
Streptococcal Scl1 and Scl2 proteins form collagen-like triple helices. J Biol Chem (2002) 1.95
Inactivation of the fibronectin-binding adhesin gene bbk32 significantly attenuates the infectivity potential of Borrelia burgdorferi. Mol Microbiol (2006) 1.93
A 'Collagen Hug' model for Staphylococcus aureus CNA binding to collagen. EMBO J (2005) 1.78
A pure population of lung alveolar epithelial type II cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2007) 1.74
Complement: a novel factor in basal and ischemia-induced neurogenesis. EMBO J (2006) 1.70
A family of putative MSCRAMMs from Enterococcus faecalis. Microbiology (2004) 1.63
The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell-mediated responses. J Clin Invest (2002) 1.63
Crystal structures of fibronectin-binding sites from Staphylococcus aureus FnBPA in complex with fibronectin domains. Proc Natl Acad Sci U S A (2008) 1.62
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin. J Cell Biol (2004) 1.61
Identification and characterization of the C3 binding domain of the Staphylococcus aureus extracellular fibrinogen-binding protein (Efb). J Biol Chem (2004) 1.55
A structural model of the Staphylococcus aureus ClfA-fibrinogen interaction opens new avenues for the design of anti-staphylococcal therapeutics. PLoS Pathog (2008) 1.55
Mycobacteria-primed macrophages and dendritic cells induce an up-regulation of complement C5a anaphylatoxin receptor (CD88) in CD3+ murine T cells. J Leukoc Biol (2006) 1.53
Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development (2009) 1.50
C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury. J Immunol (2004) 1.48
Identification and phenotypic characterization of a second collagen adhesin, Scm, and genome-based identification and analysis of 13 other predicted MSCRAMMs, including four distinct pilus loci, in Enterococcus faecium. Microbiology (2008) 1.47
Fibronectin-binding proteins of gram-positive cocci. Microbes Infect (2006) 1.47
Regulatory role of C5a in LPS-induced IL-6 production by neutrophils during sepsis. FASEB J (2003) 1.42
Absence of the complement anaphylatoxin C3a receptor suppresses Th2 effector functions in a murine model of pulmonary allergy. J Immunol (2002) 1.40
Identification and preliminary characterization of cell-wall-anchored proteins of Staphylococcus epidermidis. Microbiology (2005) 1.37
A new mechanism regulating the initiation of allergic airway inflammation. J Allergy Clin Immunol (2007) 1.37
Stimulated innate resistance of lung epithelium protects mice broadly against bacteria and fungi. Am J Respir Cell Mol Biol (2009) 1.36
Virulence potential of the staphylococcal adhesin CNA in experimental arthritis is determined by its affinity for collagen. J Infect Dis (2004) 1.36
Transplantation of human embryonic stem cell-derived alveolar epithelial type II cells abrogates acute lung injury in mice. Mol Ther (2010) 1.36
Borrelia burgdorferi lacking DbpBA exhibits an early survival defect during experimental infection. Infect Immun (2008) 1.36
Anti-clumping factor A immunoglobulin reduces the duration of methicillin-resistant Staphylococcus aureus bacteremia in an experimental model of infective endocarditis. Antimicrob Agents Chemother (2003) 1.35
A role for decorin in cutaneous wound healing and angiogenesis. Wound Repair Regen (2006) 1.33
The evolution and maintenance of virulence in Staphylococcus aureus: a role for host-to-host transmission? Nat Rev Microbiol (2006) 1.33
The tandem beta-zipper model defines high affinity fibronectin-binding repeats within Staphylococcus aureus FnBPA. J Biol Chem (2007) 1.32
Methicillin resistance reduces the virulence of healthcare-associated methicillin-resistant Staphylococcus aureus by interfering with the agr quorum sensing system. J Infect Dis (2012) 1.32
Carboxypeptidase N: a pleiotropic regulator of inflammation. Mol Immunol (2004) 1.32
Protective niche for Borrelia burgdorferi to evade humoral immunity. Am J Pathol (2004) 1.29
Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices. J Biol Chem (2007) 1.28
A streptococcal collagen-like protein interacts with the alpha2beta1 integrin and induces intracellular signaling. J Biol Chem (2005) 1.27
Borrelia burgdorferi binds fibronectin through a tandem beta-zipper, a common mechanism of fibronectin binding in staphylococci, streptococci, and spirochetes. J Biol Chem (2005) 1.27
C5a receptor deficiency attenuates T cell function and renal disease in MRLlpr mice. J Am Soc Nephrol (2005) 1.26
Assessment of prokaryotic collagen-like sequences derived from streptococcal Scl1 and Scl2 proteins as a source of recombinant GXY polymers. Appl Microbiol Biotechnol (2006) 1.26
Molecular characterization of the interaction of staphylococcal microbial surface components recognizing adhesive matrix molecules (MSCRAMM) ClfA and Fbl with fibrinogen. J Biol Chem (2009) 1.24
Fibrinogen-binding proteins of Gram-positive bacteria. Thromb Haemost (2007) 1.23
Enhancing mechanical properties of tissue-engineered constructs via lysyl oxidase crosslinking activity. J Biomed Mater Res A (2003) 1.23
Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis. FASEB J (2012) 1.21
The alternative activation pathway and complement component C3 are critical for a protective immune response against Pseudomonas aeruginosa in a murine model of pneumonia. Infect Immun (2004) 1.21
MSCRAMM--targeted vaccines and immunotherapy for staphylococcal infection. Curr Opin Drug Discov Devel (2004) 1.21
Scl1-dependent internalization of group A Streptococcus via direct interactions with the alpha2beta(1) integrin enhances pathogen survival and re-emergence. Mol Microbiol (2007) 1.21
Deletion of the complement anaphylatoxin C3a receptor attenuates, whereas ectopic expression of C3a in the brain exacerbates, experimental autoimmune encephalomyelitis. J Immunol (2004) 1.21
The receptor for complement component C3a mediates protection from intestinal ischemia-reperfusion injuries by inhibiting neutrophil mobilization. Proc Natl Acad Sci U S A (2013) 1.21
BBK32, a fibronectin binding MSCRAMM from Borrelia burgdorferi, contains a disordered region that undergoes a conformational change on ligand binding. J Biol Chem (2004) 1.17
Bone morphogenetic protein-1/tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis. J Biol Chem (2004) 1.16
Evidence for the "dock, lock, and latch" ligand binding mechanism of the staphylococcal microbial surface component recognizing adhesive matrix molecules (MSCRAMM) SdrG. J Biol Chem (2007) 1.16
A novel binding site in collagen type III for integrins alpha1beta1 and alpha2beta1. J Biol Chem (2005) 1.15
Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Proc Natl Acad Sci U S A (2008) 1.15
The regulation of liver cell survival by complement. J Immunol (2009) 1.15
High affinity streptococcal binding to human fibronectin requires specific recognition of sequential F1 modules. J Biol Chem (2004) 1.14
Identification and biochemical characterization of two novel collagen binding MSCRAMMs of Bacillus anthracis. J Biol Chem (2004) 1.13
The Enterococcus faecalis MSCRAMM ACE binds its ligand by the Collagen Hug model. J Biol Chem (2007) 1.13
Microbial etiology of travelers' diarrhea in Mexico, Guatemala, and India: importance of enterotoxigenic Bacteroides fragilis and Arcobacter species. J Clin Microbiol (2010) 1.12
Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions. J Biol Chem (2011) 1.10
Chondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I. J Bone Miner Res (2002) 1.09
Matricellular hevin regulates decorin production and collagen assembly. J Biol Chem (2006) 1.09
A protective role for the fifth complement component (c5) in allergic airway disease. Am J Respir Crit Care Med (2006) 1.09
Multicomponent Lyme vaccine: three is not a crowd. Vaccine (2005) 1.09
Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity. Mol Microbiol (2011) 1.08
Regulatory role of C5a on macrophage migration inhibitory factor release from neutrophils. J Immunol (2004) 1.07
Complement C5a anaphylatoxin is an innate determinant of dendritic cell-induced Th1 immunity to Mycobacterium bovis BCG infection in mice. J Leukoc Biol (2007) 1.06
beta-Neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC. PLoS Pathog (2010) 1.04
Collagen-binding microbial surface components recognizing adhesive matrix molecule (MSCRAMM) of Gram-positive bacteria inhibit complement activation via the classical pathway. J Biol Chem (2013) 1.04
Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia. Blood (2013) 1.03
Effect of complement component C3 deficiency on experimental Lyme borreliosis in mice. Infect Immun (2003) 1.02
Decorin-binding sites in the adhesin DbpA from Borrelia burgdorferi: a synthetic peptide approach. J Biol Chem (2003) 1.02
Procollagen C proteinase enhancer 1 genes are important determinants of the mechanical properties and geometry of bone and the ultrastructure of connective tissues. Mol Cell Biol (2006) 1.01
Decorin modulates fibrin assembly and structure. J Biol Chem (2006) 1.01
Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a. Mol Immunol (2007) 1.01
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest (2010) 1.00
Binding of Efb from Staphylococcus aureus to fibrinogen blocks neutrophil adherence. J Biol Chem (2011) 0.99
Targeted disruption of the gene encoding the murine small subunit of carboxypeptidase N (CPN1) causes susceptibility to C5a anaphylatoxin-mediated shock. J Immunol (2009) 0.98
Src kinase has a central role in in vitro cellular internalization of Staphylococcus aureus. Cell Microbiol (2003) 0.97
Effect of lactoferrin on enteroaggregative E. coli (EAEC). Biochem Cell Biol (2006) 0.97
Cooperative binding and activation of fibronectin by a bacterial surface protein. J Biol Chem (2010) 0.95
Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus. Bioorg Med Chem Lett (2010) 0.94
Entry of Bacillus anthracis spores into epithelial cells is mediated by the spore surface protein BclA, integrin α2β1 and complement component C1q. Cell Microbiol (2010) 0.93
Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties. J Med Chem (2010) 0.93
A family of fibrinogen-binding MSCRAMMs from Enterococcus faecalis. Microbiology (2009) 0.93
A novel fibronectin binding motif in MSCRAMMs targets F3 modules. PLoS One (2009) 0.92
Invasion of eukaryotic cells by Borrelia burgdorferi requires β(1) integrins and Src kinase activity. Infect Immun (2010) 0.92
An engineered alpha1 integrin-binding collagenous sequence. J Biol Chem (2010) 0.92