Published in Virology on September 01, 2004
The remarkable frequency of human immunodeficiency virus type 1 genetic recombination. Microbiol Mol Biol Rev (2009) 2.02
HIV-1 reverse transcription. Cold Spring Harb Perspect Med (2012) 1.29
Influence of sequence identity and unique breakpoints on the frequency of intersubtype HIV-1 recombination. Retrovirology (2006) 1.03
Mechanisms and factors that influence high frequency retroviral recombination. Viruses (2011) 1.02
Genetic recombination between human immunodeficiency virus type 1 (HIV-1) and HIV-2, two distinct human lentiviruses. J Virol (2007) 1.00
RNA structures facilitate recombination-mediated gene swapping in HIV-1. J Virol (2010) 0.99
Phylogenetic mapping of recombination hotspots in human immunodeficiency virus via spatially smoothed change-point processes. Genetics (2006) 0.98
Pausing during reverse transcription increases the rate of retroviral recombination. J Virol (2006) 0.94
Identifying recombination hot spots in the HIV-1 genome. J Virol (2013) 0.93
U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence. Biochemistry (2014) 0.92
Fifteen to twenty percent of HIV substitution mutations are associated with recombination. J Virol (2014) 0.91
Accurately measuring recombination between closely related HIV-1 genomes. PLoS Comput Biol (2010) 0.90
A recombination hot spot in HIV-1 contains guanosine runs that can form a G-quartet structure and promote strand transfer in vitro. J Biol Chem (2009) 0.88
Long-range recombination gradient between HIV-1 subtypes B and C variants caused by sequence differences in the dimerization initiation signal region. J Mol Biol (2008) 0.87
Sequences in the U3 region of human immunodeficiency virus 1 improve efficiency of minus strand transfer in infected cells. Virology (2010) 0.80
Effects of identity minimization on Moloney murine leukemia virus template recognition and frequent tertiary template-directed insertions during nonhomologous recombination. J Virol (2007) 0.80
Human immunodeficiency virus type 1 protease inhibitor drug-resistant mutants give discordant results when compared in single-cycle and multiple-cycle fitness assays. J Clin Microbiol (2010) 0.80
Feline immunodeficiency virus (FIV) env recombinants are common in natural infections. Retrovirology (2014) 0.79
HIV-1 nucleocapsid protein increases strand transfer recombination by promoting dimeric G-quartet formation. J Biol Chem (2011) 0.78
Mechanism of HIV-1 RNA dimerization in the central region of the genome and significance for viral evolution. J Biol Chem (2013) 0.78
Cross- and Co-Packaging of Retroviral RNAs and Their Consequences. Viruses (2016) 0.75
Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA Panel. Clin Infect Dis (2003) 4.51
Flap endonuclease 1: a central component of DNA metabolism. Annu Rev Biochem (2004) 3.16
Macrophage tropism of HIV-1 depends on efficient cellular dNTP utilization by reverse transcriptase. J Biol Chem (2004) 3.10
Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells. Blood (2008) 3.05
Epigenetic regulation of HIV-1 latency by cytosine methylation. PLoS Pathog (2009) 2.50
Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R. J Biol Chem (2003) 2.26
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell (2005) 2.19
Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate. J Biol Chem (2002) 2.06
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (2005) 1.93
Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A (2011) 1.92
Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis. Dev Biol (2006) 1.91
HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system. Virol J (2007) 1.89
BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle (2012) 1.88
Host factors influencing susceptibility to HIV infection and AIDS progression. Retrovirology (2007) 1.77
Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu. Cell Host Microbe (2010) 1.74
Drug resistance mutations in HIV-1. Top HIV Med (2003) 1.72
On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing. J Biol Chem (2004) 1.72
HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response. PLoS Pathog (2009) 1.71
Lagging strand replication proteins in genome stability and DNA repair. Chem Rev (2006) 1.71
Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun (2011) 1.69
HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT. PLoS Pathog (2006) 1.67
Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome. Am J Physiol Heart Circ Physiol (2005) 1.67
Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation. Mol Cell Biol (2004) 1.66
Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells. PLoS Pathog (2011) 1.64
Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. J Biol Chem (2004) 1.63
Update of the drug resistance mutations in HIV-1: 2004. Top HIV Med (2004) 1.62
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. Mol Biol Cell (2003) 1.61
The protein components and mechanism of eukaryotic Okazaki fragment maturation. Crit Rev Biochem Mol Biol (2003) 1.57
Analysing complete genome sequence of swine hepatitis E virus (HEV), strain CHN-XJ-SW13 isolated from Xinjiang, China: putative host range, and disease severity determinants in HEV. Infect Genet Evol (2011) 1.54
Strand transfer events during HIV-1 reverse transcription. Virus Res (2008) 1.51
A randomized trial of 2 different 4-drug antiretroviral regimens versus a 3-drug regimen, in advanced human immunodeficiency virus disease. J Infect Dis (2003) 1.51
The human Rad9-Rad1-Hus1 checkpoint complex stimulates flap endonuclease 1. Proc Natl Acad Sci U S A (2004) 1.49
Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. J Virol (2006) 1.47
No evidence for decay of the latent reservoir in HIV-1-infected patients receiving intensive enfuvirtide-containing antiretroviral therapy. J Infect Dis (2010) 1.45
Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy. Retrovirology (2008) 1.44
Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal. J Biol Chem (2008) 1.43
HIV latency and integration site placement in five cell-based models. Retrovirology (2013) 1.42
A role for dNTP binding of human immunodeficiency virus type 1 reverse transcriptase in viral mutagenesis. Biochemistry (2004) 1.41
Modeling and estimation of replication fitness of human immunodeficiency virus type 1 in vitro experiments by using a growth competition assay. J Virol (2006) 1.41
Differential equation modeling of HIV viral fitness experiments: model identification, model selection, and multimodel inference. Biometrics (2008) 1.38
Reconstituted Okazaki fragment processing indicates two pathways of primer removal. J Biol Chem (2006) 1.38
Drug resistance mutations in HIV-1. Top HIV Med (2004) 1.37
Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo. J Virol (2005) 1.34
Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation. J Biol Chem (2004) 1.34
Prevalence of human papillomavirus genotypes and related abnormalities of cervical cytological results among HIV-1-infected women in Rochester, New York. J Infect Dis (2006) 1.32
Clinical significance of human immunodeficiency virus type 1 replication fitness. Clin Microbiol Rev (2007) 1.31
Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells. Methods (2010) 1.29
HIV-1 Vpr: mechanisms of G2 arrest and apoptosis. Exp Mol Pathol (2008) 1.29
Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway. J Biol Chem (2009) 1.27
Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiae. J Biol Chem (2008) 1.24
Template dimerization promotes an acceptor invasion-induced transfer mechanism during human immunodeficiency virus type 1 minus-strand synthesis. J Virol (2003) 1.24
RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information. J Med Chem (2009) 1.24
The role of Vpr in HIV-1 pathogenesis. Curr HIV Res (2005) 1.24
Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA. AIDS Res Hum Retroviruses (2003) 1.23
Reduced dNTP binding affinity of 3TC-resistant M184I HIV-1 reverse transcriptase variants responsible for viral infection failure in macrophage. J Biol Chem (2008) 1.23
Evidence that DNA damage detection machinery participates in DNA repair. Cell Cycle (2005) 1.23
Single-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathways. Mol Cell Biol (2004) 1.23
Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability. Mol Cell Biol (2004) 1.22
Current status of gene therapy strategies to treat HIV/AIDS. Mol Ther (2005) 1.21
Flap endonuclease 1. Annu Rev Biochem (2013) 1.21
Endostatin gene transfer inhibits joint angiogenesis and pannus formation in inflammatory arthritis. Mol Ther (2002) 1.19
Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates. J Biol Chem (2009) 1.18
The effects of estrogen-responsive element- and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ER alpha and ER beta. Mol Endocrinol (2002) 1.18
Okazaki fragment metabolism. Cold Spring Harb Perspect Biol (2013) 1.17
Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments. Bull Math Biol (2008) 1.17
Phosphatidylinositol 3-kinase inhibition by LY294002 radiosensitizes human cervical cancer cell lines. Clin Cancer Res (2006) 1.17
Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation. J Virol (2007) 1.16
Structural and binding analysis of pyrimidinol carboxylic acid and N-hydroxy quinazolinedione HIV-1 RNase H inhibitors. Antimicrob Agents Chemother (2011) 1.16
Mechanism of stimulation of human DNA ligase I by the Rad9-rad1-Hus1 checkpoint complex. J Biol Chem (2006) 1.15
Induction of cell cycle arrest by human T-cell lymphotropic virus type 1 Tax in hematopoietic progenitor (CD34+) cells: modulation of p21cip1/waf1 and p27kip1 expression. J Virol (2005) 1.13
Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque. J Biol Chem (2003) 1.13
Detection of drug-resistant minority variants of HIV-1 during virologic failure of indinavir, lamivudine, and zidovudine. J Infect Dis (2004) 1.12
Apparent defects in processive DNA synthesis, strand transfer, and primer elongation of Met-184 mutants of HIV-1 reverse transcriptase derive solely from a dNTP utilization defect. J Biol Chem (2008) 1.12
Evaluation of a multiple-cycle, recombinant virus, growth competition assay that uses flow cytometry to measure replication efficiency of human immunodeficiency virus type 1 in cell culture. J Clin Microbiol (2006) 1.10
Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion. J Biol Chem (2003) 1.10
Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading. J Biol Chem (2010) 1.09
Efficiency of lentiviral transduction during development in normal and rd mice. Mol Vis (2006) 1.09
GTP is the primary activator of the anti-HIV restriction factor SAMHD1. J Biol Chem (2013) 1.09
Eukaryotic lagging strand DNA replication employs a multi-pathway mechanism that protects genome integrity. J Biol Chem (2010) 1.08
Long patch base excision repair proceeds via coordinated stimulation of the multienzyme DNA repair complex. J Biol Chem (2009) 1.08
Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells. J Virol (2012) 1.08
Role of the Reverse Transcriptase, Nucleocapsid Protein, and Template Structure in the Two-step Transfer Mechanism in Retroviral Recombination. J Biol Chem (2003) 1.07
Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line. J Mol Biol (2006) 1.07
AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair. J Biol Chem (2002) 1.07
Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation. Retrovirology (2013) 1.06
Strand transfer occurs in retroviruses by a pause-initiated two-step mechanism. J Biol Chem (2002) 1.06
HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. Kidney Int (2008) 1.05
Flap endonuclease 1 efficiently cleaves base excision repair and DNA replication intermediates assembled into nucleosomes. Mol Cell (2002) 1.05
DNA ligase I competes with FEN1 to expand repetitive DNA sequences in vitro. J Biol Chem (2002) 1.04