Published in Methods Mol Biol on January 01, 2004
Structure and function of snake venom proteins affecting platelet plug formation. Toxins (Basel) (2009) 0.78
Heterologous fibrin sealant derived from snake venom: from bench to bedside - an overview. J Venom Anim Toxins Incl Trop Dis (2017) 0.77
Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry (2006) 1.99
Platelet physiology and thrombosis. Thromb Res (2004) 1.90
High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction. Blood (2010) 1.75
Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets. Blood (2011) 1.56
The dimeric versus monomeric status of 14-3-3zeta is controlled by phosphorylation of Ser58 at the dimer interface. J Biol Chem (2003) 1.49
Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members. Blood (2005) 1.47
Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa. Blood (2011) 1.44
Association of Fyn and Lyn with the proline-rich domain of glycoprotein VI regulates intracellular signaling. J Biol Chem (2002) 1.39
P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface. Blood (2003) 1.34
Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo. Blood (2006) 1.22
Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. Blood (2005) 1.21
A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood (2005) 1.20
Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene. J Biol Chem (2006) 1.12
Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway. Blood (2008) 1.11
Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase. Blood (2002) 1.09
Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta). J Biol Chem (2002) 1.09
Anti-beta2-glycoprotein I antibodies in complex with beta2-glycoprotein I can activate platelets in a dysregulated manner via glycoprotein Ib-IX-V. Arthritis Rheum (2006) 1.09
Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa. Blood (2007) 1.06
Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase. Blood (2004) 1.04
Leucine-rich repeats 2-4 (Leu60-Glu128) of platelet glycoprotein Ibalpha regulate shear-dependent cell adhesion to von Willebrand factor. J Biol Chem (2006) 1.03
Bernard-Soulier syndrome. Haematologica (2011) 1.00
Platelet adhesion: a game of catch and release. J Clin Invest (2008) 1.00
Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. Blood (2004) 0.99
Glycoprotein VI is associated with GPIb-IX-V on the membrane of resting and activated platelets. Thromb Haemost (2005) 0.98
The LFA-1-associated molecule PTA-1 (CD226) on T cells forms a dynamic molecular complex with protein 4.1G and human discs large. J Biol Chem (2004) 0.96
Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1. Circ Res (2008) 0.95
Delineation of the region in the glycoprotein VI tail required for association with the Fc receptor gamma-chain. J Biol Chem (2003) 0.93
Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity. Arterioscler Thromb Vasc Biol (2007) 0.92
The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation. Arterioscler Thromb Vasc Biol (2012) 0.92
Antihemostatic activity of human granzyme B mediated by cleavage of von Willebrand factor. J Biol Chem (2008) 0.92
Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood. J Biol Chem (2012) 0.92
Proteolysis of platelet receptors in humans and other species. Biol Chem (2010) 0.91
Platelet receptor redox regulation. Platelets (2008) 0.88
The cryptome: a subset of the proteome, comprising cryptic peptides with distinct bioactivities. Drug Discov Today (2006) 0.88
LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis. Blood (2013) 0.88
Interaction of calmodulin with the cytoplasmic domain of platelet glycoprotein VI. Blood (2002) 0.87
Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels. Blood (2012) 0.87
Platelet interactions in thrombosis. IUBMB Life (2004) 0.86
SHIP-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V: localization of SHIP-2 to the activated platelet actin cytoskeleton. Blood (2003) 0.86
Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha. J Biol Chem (2010) 0.86
Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke. Stroke (2010) 0.85
Binding of von Willebrand factor to the small proteoglycan decorin. FEBS Lett (2004) 0.84
Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane. J Biol Chem (2007) 0.84
Role of calmodulin in platelet receptor function. Curr Med Chem Cardiovasc Hematol Agents (2005) 0.84
Snake venom probes of platelet adhesion receptors and their ligands. Toxicon (2005) 0.83
Primary platelet adhesion receptors. IUBMB Life (2005) 0.83
Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding. Platelets (2009) 0.83
Polymorphisms and interspecies differences of the activating and inhibitory FcγRII of Macaca nemestrina influence the binding of human IgG subclasses. J Immunol (2013) 0.82
Fractionation of snake venom metalloproteinases by metal ion affinity: a purified cobra metalloproteinase, Nk, from Naja kaouthia binds Ni2+-agarose. Toxicon (2007) 0.81
Bernard-Soulier syndrome: an update. Semin Thromb Hemost (2013) 0.81
Characterization of a myeloma patient with a life-threatening hemorrhagic diathesis: presence of a lambda dimer protein inhibiting shear-induced platelet aggregation by binding to the A1 domain of von Willebrand factor. Thromb Haemost (2005) 0.81
GPIbalpha-selective activation of platelets induces platelet signaling events comparable to GPVI activation events. Platelets (2010) 0.80
Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation. Mol Pharmacol (2003) 0.80
Cadherin 6 has a functional role in platelet aggregation and thrombus formation. Arterioscler Thromb Vasc Biol (2012) 0.80
The functional role of platelets in the regulation of angiogenesis. Platelets (2014) 0.80
Phase I pilot clinical trial of antenatal maternally administered melatonin to decrease the level of oxidative stress in human pregnancies affected by pre-eclampsia (PAMPR): study protocol. BMJ Open (2013) 0.79
A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway. Br J Haematol (2007) 0.79
The 14-3-3zeta-GPIb-IX-V complex as an antiplatelet target. Drug News Perspect (2007) 0.78
Measuring soluble platelet glycoprotein VI in human plasma by ELISA. Platelets (2009) 0.78
Structure-activity relationships of snake toxins targeting platelet receptors, glycoprotein Ib-IX-V and glycoprotein VI. Curr Med Chem Cardiovasc Hematol Agents (2003) 0.78
Platelets: envoys at the infection frontline. J Infect Dis (2013) 0.78
Platelet receptor shedding. Methods Mol Biol (2012) 0.77
Calmodulin interacts with the platelet ADP receptor P2Y1. Biochem J (2006) 0.77
Functional analysis of the C-terminal flanking sequence of platelet glycoprotein Ib alpha using canine-human chimeras. Blood (2002) 0.77
Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI. J Biol Chem (2010) 0.77
Histone deacetylase inhibitors reduce glycoprotein VI expression and platelet responses to collagen related peptide. Thromb Res (2013) 0.76
Platelet physiology: in cold blood. Curr Biol (2003) 0.76
Diesel exhaust particles impair platelet response to collagen and are associated with GPIbα shedding. Toxicol In Vitro (2012) 0.76
Snake venom metalloproteinases, crotarhagin and alborhagin, induce ectodomain shedding of the platelet collagen receptor, glycoprotein VI. Thromb Haemost (2007) 0.75
Inside platelets... Blood (2012) 0.75
Induction of platelet-endothelial interactions in postcapillary venules in hypercholesterolemia: critical role of P-selectin. Arterioscler Thromb Vasc Biol (2003) 0.75
An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI. Acta Haematol (2012) 0.75
Platelet hem-immunoreceptor tyrosine-based activation motif receptors: at least one required. Arterioscler Thromb Vasc Biol (2013) 0.75
Arterial thrombosis: going, gone! Blood (2010) 0.75
New direction for WE thrombin. Arterioscler Thromb Vasc Biol (2008) 0.75
Microparticles facilitate neutrophil/platelet crosstalk. Blood (2008) 0.75
An event of shear importance. Blood (2011) 0.75
Restored platelet function after romiplostim treatment in a patient with immune thrombocytopenic purpura. Br J Haematol (2010) 0.75