Published in Cell Commun Adhes on December 01, 2009
A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells. Sci Signal (2015) 1.53
Targeting pannexin1 improves seizure outcome. PLoS One (2011) 1.43
ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes. Glia (2012) 1.22
Pannexin1 regulates α1-adrenergic receptor- mediated vasoconstriction. Circ Res (2011) 1.21
The ATP permeability of pannexin 1 channels in a heterologous system and in mammalian taste cells is dispensable. J Cell Sci (2012) 1.16
Pannexin1 stabilizes synaptic plasticity and is needed for learning. PLoS One (2012) 1.07
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow. J Cell Physiol (2012) 1.06
K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharmacol (2012) 1.04
Is pannexin the pore associated with the P2X7 receptor? Naunyn Schmiedebergs Arch Pharmacol (2013) 0.95
Roles of gap junctions, connexins, and pannexins in epilepsy. Front Physiol (2014) 0.94
Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"? J Membr Biol (2012) 0.94
The bizarre pharmacology of the ATP release channel pannexin1. Neuropharmacology (2013) 0.93
Nature of plasmalemmal functional "hemichannels". Biochim Biophys Acta (2011) 0.93
Mechanisms of ATP release, the enabling step in purinergic dynamics. Cell Physiol Biochem (2011) 0.92
Contribution of pannexin1 to experimental autoimmune encephalomyelitis. PLoS One (2013) 0.91
Regulation of cellular communication by signaling microdomains in the blood vessel wall. Pharmacol Rev (2014) 0.90
Pannexin 1 channels play essential roles in urothelial mechanotransduction and intercellular signaling. PLoS One (2014) 0.86
P2X receptor stimulation amplifies complement-induced haemolysis. Pflugers Arch (2012) 0.82
Emerging functions of pannexin 1 in the eye. Front Cell Neurosci (2014) 0.81
Thalamic modulation of cingulate seizure activity via the regulation of gap junctions in mice thalamocingulate slice. PLoS One (2013) 0.80
Emerging concepts regarding pannexin 1 in the vasculature. Biochem Soc Trans (2015) 0.78
Inhibition of connexin 43 hemichannel-mediated ATP release attenuates early inflammation during the foreign body response. Tissue Eng Part A (2015) 0.78
Pannexin 1 channels in skeletal muscles. Front Physiol (2014) 0.76
Regulation of extracellular ATP in human erythrocytes infected with Plasmodium falciparum. PLoS One (2014) 0.76
A small-fish model for behavioral-toxicological screening of new antimalarial drugs: a comparison between erythro- and threo-mefloquine. BMC Res Notes (2015) 0.75
Mechanism of Action of the Anti-Inflammatory Connexin43-Mimetic Peptide JM2. Am J Physiol Cell Physiol (2017) 0.75
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity (2007) 6.75
Pannexin membrane channels are mechanosensitive conduits for ATP. FEBS Lett (2004) 4.73
Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium. FEBS Lett (2005) 3.89
Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes. J Neurochem (2005) 3.87
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J Neurosci (2006) 3.14
Ischemia opens neuronal gap junction hemichannels. Science (2006) 3.00
The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem (2009) 2.90
P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage. J Immunol (2008) 2.72
Potent block of Cx36 and Cx50 gap junction channels by mefloquine. Proc Natl Acad Sci U S A (2004) 2.61
P2X7 receptor-Pannexin1 complex: pharmacology and signaling. Am J Physiol Cell Physiol (2008) 2.49
Pannexin 1: the molecular substrate of astrocyte "hemichannels". J Neurosci (2009) 2.48
Amazing chloride channels: an overview. Acta Physiol Scand (2003) 2.42
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. J Pharmacol Exp Ther (2008) 2.42
Functional connexin "hemichannels": a critical appraisal. Glia (2006) 2.21
Cell-cell communication beyond connexins: the pannexin channels. Physiology (Bethesda) (2006) 2.13
Evolution of gap junction proteins--the pannexin alternative. J Exp Biol (2005) 1.88
Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Res Brain Res Rev (2004) 1.54
Astrocytic swelling in cerebral ischemia as a possible cause of injury and target for therapy. Glia (2005) 1.53
Functional characteristics of skate connexin35, a member of the gamma subfamily of connexins expressed in the vertebrate retina. Eur J Neurosci (1999) 1.33
Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis. Proc Natl Acad Sci U S A (2009) 1.30
Discovery of nonxanthine adenosine A2A receptor antagonists for the treatment of Parkinson's disease. Neurology (2003) 1.11
Hemichannels in cerebral ischemia. Curr Mol Med (2009) 1.07
Transfection of mammalian cells with connexins and measurement of voltage sensitivity of their gap junctions. Nat Protoc (2006) 1.04
Stereoselectivity in the pharmacodynamics and pharmacokinetics of the chiral antimalarial drugs. Clin Pharmacokinet (2003) 1.02
Reversion of gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy after transplantation of bone marrow cells. Cell Cycle (2011) 3.49
Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex. FEBS Lett (2007) 3.19
P2X7 receptors mediate ATP release and amplification of astrocytic intercellular Ca2+ signaling. J Neurosci (2006) 3.14
The pannexin 1 channel activates the inflammasome in neurons and astrocytes. J Biol Chem (2009) 2.90
Spatial and temporal control of cofilin activity is required for directional sensing during chemotaxis. Curr Biol (2006) 2.86
Potent block of Cx36 and Cx50 gap junction channels by mefloquine. Proc Natl Acad Sci U S A (2004) 2.61
Pannexin 1: the molecular substrate of astrocyte "hemichannels". J Neurosci (2009) 2.48
The role of the glycocalyx in reorganization of the actin cytoskeleton under fluid shear stress: a "bumper-car" model. Proc Natl Acad Sci U S A (2004) 2.05
Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1. J Biol Chem (2004) 2.03
Imaging the endothelial glycocalyx in vitro by rapid freezing/freeze substitution transmission electron microscopy. Arterioscler Thromb Vasc Biol (2011) 1.89
Glial cells in (patho)physiology. J Neurochem (2012) 1.89
Connexin and pannexin mediated cell-cell communication. Neuron Glia Biol (2007) 1.86
Pannexin channels are not gap junction hemichannels. Channels (Austin) (2011) 1.84
Connexin family members target to lipid raft domains and interact with caveolin-1. Biochemistry (2002) 1.66
Perspectives on Trypanosoma cruzi-induced heart disease (Chagas disease). Prog Cardiovasc Dis (2009) 1.60
pH-dependent intramolecular binding and structure involving Cx43 cytoplasmic domains. J Biol Chem (2002) 1.59
Mechanisms of glutamate release from astrocytes: gap junction "hemichannels", purinergic receptors and exocytotic release. Neurochem Int (2004) 1.53
The role of connexins in controlling cell growth and gene expression. Prog Biophys Mol Biol (2007) 1.48
Connexins, pannexins, innexins: novel roles of "hemi-channels". Pflugers Arch (2008) 1.45
Gap junctions mediate bystander cell death in developing retina. J Neurosci (2003) 1.43
Targeting pannexin1 improves seizure outcome. PLoS One (2011) 1.43
Regulation of connexin43 protein complexes by intracellular acidification. Circ Res (2003) 1.43
The cytokine IL-1beta transiently enhances P2X7 receptor expression and function in human astrocytes. Glia (2005) 1.42
Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia. Stroke (2005) 1.36
Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia. Proc Natl Acad Sci U S A (2007) 1.33
The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors. Proc Natl Acad Sci U S A (2008) 1.28
New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relationship with connexin43. FASEB J (2005) 1.28
pH-dependent dimerization of the carboxyl terminal domain of Cx43. Biophys J (2004) 1.26
Array analysis of gene expression in connexin-43 null astrocytes. Physiol Genomics (2003) 1.24
ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes. Glia (2012) 1.22
Acute downregulation of Cx43 alters P2Y receptor expression levels in mouse spinal cord astrocytes. Glia (2003) 1.21
Closure of gap junction channels by arylaminobenzoates. Mol Pharmacol (2003) 1.21
Genes controlling multiple functional pathways are transcriptionally regulated in connexin43 null mouse heart. Physiol Genomics (2004) 1.20
Block of specific gap junction channel subtypes by 2-aminoethoxydiphenyl borate (2-APB). J Pharmacol Exp Ther (2006) 1.20
Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy. Parasitol Res (2003) 1.19
Optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging. J Nanobiotechnology (2011) 1.19
Fluid shear stress remodels expression and function of junctional proteins in cultured bone cells. Am J Physiol Cell Physiol (2002) 1.18
Cognitive dysfunction in mice infected with Plasmodium berghei strain ANKA. J Infect Dis (2008) 1.16
Exocytosis of ATP from astrocyte progenitors modulates spontaneous Ca2+ oscillations and cell migration. Glia (2007) 1.16
Bone marrow cell therapy ameliorates and reverses chagasic cardiomyopathy in a mouse model. J Infect Dis (2008) 1.16
Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner. Mol Biol Cell (2012) 1.15
Sensitivity of the brain transcriptome to connexin ablation. Biochim Biophys Acta (2004) 1.14
Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis. J Neurosci Res (2005) 1.14
Gene expression alterations in connexin null mice extend beyond the gap junction. Neurochem Int (2004) 1.12
Modifications in the biophysical properties of connexin43 channels by a peptide of the cytoplasmic loop region. Circ Res (2004) 1.11
Flow cytometry analysis of gap junction-mediated cell-cell communication: advantages and pitfalls. Cytometry A (2006) 1.10
Acquired infection with Toxoplasma gondii in adult mice results in sensorimotor deficits but normal cognitive behavior despite widespread brain pathology. Microbes Infect (2010) 1.09
A comparative antibody analysis of pannexin1 expression in four rat brain regions reveals varying subcellular localizations. Front Pharmacol (2013) 1.09
Cardiac connexins: genes to nexus. Adv Cardiol (2006) 1.08
Formation of the gap junction nexus: binding partners for connexins. J Physiol Paris (2002) 1.08
Similar transcriptomic alterations in Cx43 knockdown and knockout astrocytes. Cell Commun Adhes (2008) 1.07
Automated cell-based assay for screening of aquaporin inhibitors. Anal Chem (2009) 1.06
Sequence-specific resonance assignment of the carboxyl terminal domain of Connexin43. J Biomol NMR (2002) 1.04
Transfection of mammalian cells with connexins and measurement of voltage sensitivity of their gap junctions. Nat Protoc (2006) 1.04
Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia. J Biol Chem (2004) 1.02
Chagas heart disease: report on recent developments. Cardiol Rev (2012) 1.02
Bidirectional calcium signaling between satellite glial cells and neurons in cultured mouse trigeminal ganglia. Neuron Glia Biol (2009) 1.01
The TLR3 ligand polyI: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the NF-kappaB and PI3 kinase pathways. Glia (2006) 1.01
Microarray technology in the investigation of diseases of myocardium with special reference to infection. Front Biosci (2006) 1.00
Two non-vesicular ATP release pathways in the mouse erythrocyte membrane. FEBS Lett (2011) 1.00
Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria. Microbes Infect (2010) 1.00
Characterization of hTERT-immortalized osteoblast cell lines generated from wild-type and connexin43-null mouse calvaria. Am J Physiol Cell Physiol (2010) 0.98
Transcriptomic changes in developing kidney exposed to chronic hypoxia. Biochem Biophys Res Commun (2006) 0.98
Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model. Sci Rep (2013) 0.98
Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection. Genomics (2008) 0.97
Promises and pitfalls of a Pannexin1 transgenic mouse line. Front Pharmacol (2013) 0.97
Molecular basis for pacemaker cells in epithelia. J Biol Chem (2002) 0.95
Connexins induce and maintain tight junctions in epithelial cells. J Membr Biol (2007) 0.95
Trypanosoma cruzi induces changes in cardiac connexin43 expression. Microbes Infect (2007) 0.94
The carboxyl-terminal domain of connexin43 is a negative modulator of neuronal differentiation. J Biol Chem (2010) 0.94
Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"? J Membr Biol (2012) 0.94
Mesenchymal bone marrow cell therapy in a mouse model of chagas disease. Where do the cells go? PLoS Negl Trop Dis (2012) 0.93
The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1. J Biol Chem (2007) 0.93
Connexin-dependent transcellular transcriptomic networks in mouse brain. Prog Biophys Mol Biol (2007) 0.93
Effects of ageing and streptozotocin-induced diabetes on connexin43 and P2 purinoceptor expression in the rat corpora cavernosa and urinary bladder. BJU Int (2009) 0.93
Cx32 formation and/or Cx32-mediated intercellular communication induces expression and function of tight junctions in hepatocytic cell line. Exp Cell Res (2002) 0.92
Molecular cloning and functional expression of zfCx52.6: a novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina. J Biol Chem (2003) 0.91
Contribution of pannexin1 to experimental autoimmune encephalomyelitis. PLoS One (2013) 0.91
Labeling stem cells with superparamagnetic iron oxide nanoparticles: analysis of the labeling efficacy by microscopy and magnetic resonance imaging. Methods Mol Biol (2012) 0.91
Point mutation in the mouse P2X7 receptor affects intercellular calcium waves in astrocytes. ASN Neuro (2009) 0.91
Reciprocal influence of connexins and apical junction proteins on their expressions and functions. Biochim Biophys Acta (2008) 0.91
A developmental switch in the expression of aquaporin-4 and Kir4.1 from horizontal to Müller cells in mouse retina. Invest Ophthalmol Vis Sci (2005) 0.91
On the electrophysiological response of bone cells using a Stokesian fluid stimulus probe for delivery of quantifiable localized picoNewton level forces. J Biomech (2011) 0.91
Trifluoroethanol reveals helical propensity at analogous positions in cytoplasmic domains of three connexins. Biopolymers (2009) 0.90
Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics. J Membr Biol (2007) 0.90
In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motors. J Biol Chem (2011) 0.90