Published in Hum Mol Genet on August 27, 2004
The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression. Proc Natl Acad Sci U S A (2006) 1.67
Menin: a scaffold protein that controls gene expression and cell signaling. Trends Biochem Sci (2013) 1.21
Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome. Mol Cancer (2005) 1.05
Menin is a regulator of the stress response in Drosophila melanogaster. Mol Cell Biol (2005) 1.00
Characterization of DNA damage-dependent cell cycle checkpoints in a menin-deficient model. DNA Repair (Amst) (2009) 0.85
MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair. Mol Cell Biol (2013) 0.83
MEN1 and FANCD2 mediate distinct mechanisms of DNA crosslink repair. DNA Repair (Amst) (2008) 0.82
MEN1, MEN4, and Carney Complex: Pathology and Molecular Genetics. Neuroendocrinology (2015) 0.80
Multiple endocrine neoplasia type 1 (MEN1) as a cancer predisposition syndrome: clues into the mechanisms of MEN1-related carcinogenesis. Yale J Biol Med (2006) 0.79
Imaging in multiple endocrine neoplasia type 1: recent studies show enhanced sensitivities but increased controversies. Int J Endocr Oncol (2016) 0.79
Menin and bone metabolism. J Bone Miner Metab (2012) 0.78
Genetic interactions between Drosophila melanogaster menin and Jun/Fos. Dev Biol (2006) 0.78
Menin links the stress response to genome stability in Drosophila melanogaster. PLoS One (2010) 0.77
Treatment of Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1: Some Clarity But Continued Controversy. Pancreas (2017) 0.75
Genetics of multiple endocrine neoplasia type 1 syndrome: what's new and what's old. F1000Res (2017) 0.75
Mutation in the Drosophila melanogaster adenosine receptor gene selectively decreases the mosaic hyperplastic epithelial outgrowth rates in wts or dco heterozygous flies. Purinergic Signal (2014) 0.75
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev (2003) 9.58
Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol (2002) 8.04
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice. Cell (2005) 7.29
Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol (2006) 4.28
A genetic screen in Drosophila for metastatic behavior. Science (2003) 4.09
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. Proc Natl Acad Sci U S A (2011) 3.10
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron (2009) 3.10
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice. Dev Cell (2007) 3.09
Outcome of conservatively managed early-onset breast cancer by BRCA1/2 status. Lancet (2002) 3.04
CD14 controls the LPS-induced endocytosis of Toll-like receptor 4. Cell (2011) 3.00
Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature (2010) 2.79
Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila. Curr Biol (2006) 2.63
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation. Development (2007) 2.27
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population. Epilepsia (2008) 2.27
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice. Proc Natl Acad Sci U S A (2009) 2.07
Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila. Dev Cell (2011) 2.07
Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. Proc Natl Acad Sci U S A (2007) 1.97
Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila. Dev Cell (2009) 1.95
LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1. Nat Cell Biol (2004) 1.86
An innate immune response of blood cells to tumors and tissue damage in Drosophila. Dis Model Mech (2008) 1.84
Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. Science (2009) 1.83
Variant in the glucokinase regulatory protein (GCKR) gene is associated with fatty liver in obese children and adolescents. Hepatology (2011) 1.79
Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer. Cancer Res (2006) 1.78
Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused. Development (2005) 1.75
A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents. Hepatology (2010) 1.71
Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila. Dev Cell (2007) 1.68
Mutations and polymorphisms in the human ornithine transcarbamylase (OTC) gene. Hum Mutat (2006) 1.61
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet (2010) 1.59
Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. Am J Hum Genet (2012) 1.49
FGFR1 and FGFR2 mutations in Pfeiffer syndrome. J Craniofac Surg (2013) 1.46
Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. J Biol Chem (2001) 1.46
Heterozygous nonsense mutation SATB2 associated with cleft palate, osteoporosis, and cognitive defects. Hum Mutat (2007) 1.44
Diagnostic accuracy of quantitative angiographic and intravascular ultrasound parameters predicting the functional significance of single de novo lesions. Int J Cardiol (2012) 1.42
A large-scale functional approach to uncover human genes and pathways in Drosophila. Cell Res (2008) 1.42
Shaping cells and organs in Drosophila by opposing roles of fat body-secreted Collagen IV and perlecan. Dev Cell (2011) 1.41
LATS1 tumor suppressor regulates G2/M transition and apoptosis. Oncogene (2002) 1.38
ADAM10 is essential for proteolytic activation of Notch during thymocyte development. Int Immunol (2008) 1.38
PGR +331 A/G and increased risk of epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev (2006) 1.37
A cell-intrinsic role for Mst1 in regulating thymocyte egress. J Immunol (2009) 1.35
Drosophila atrophin homolog functions as a transcriptional corepressor in multiple developmental processes. Cell (2002) 1.29
Indoor tanning and risk of early-onset basal cell carcinoma. J Am Acad Dermatol (2011) 1.26
Host phenotype characteristics and MC1R in relation to early-onset basal cell carcinoma. J Invest Dermatol (2011) 1.19
A Gateway MultiSite recombination cloning toolkit. PLoS One (2011) 1.17
Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20. Immunity (2013) 1.15
Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates. BMC Public Health (2012) 1.14
Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response. Cancer Res (2006) 1.13
The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis. Dev Biol (2005) 1.10
Incidence of BRCA1 and BRCA2 mutations in young Korean breast cancer patients. J Clin Oncol (2004) 1.09
PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Res (2007) 1.07
The expanding role of mouse genetics for understanding human biology and disease. Dis Model Mech (2008) 1.05
Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response. Curr Biol (2012) 1.05
Modeling Sjögren's syndrome with Id3 conditional knockout mice. Immunol Lett (2011) 1.05
Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma. Proc Natl Acad Sci U S A (2013) 1.04
Drosophila Src-family kinases function with Csk to regulate cell proliferation and apoptosis. Oncogene (2004) 1.03
Drosophila homologs of FANCD2 and FANCL function in DNA repair. DNA Repair (Amst) (2006) 1.02
Coiled versus straight peritoneal dialysis catheters: a randomized controlled trial and meta-analysis. Am J Kidney Dis (2011) 1.02
Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA. J Biol Chem (2005) 1.01
ELF1 is associated with systemic lupus erythematosus in Asian populations. Hum Mol Genet (2010) 0.99
Rhabdomyosarcoma, Wilms tumor, and deletion of the patched gene in Gorlin syndrome. Nat Clin Pract Oncol (2006) 0.99
Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Hum Mol Genet (2011) 0.97
A genetic screen for modifiers of the lats tumor suppressor gene identifies C-terminal Src kinase as a regulator of cell proliferation in Drosophila. Oncogene (2003) 0.95
piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice. PLoS One (2011) 0.95
LATS1 tumor suppressor is a novel actin-binding protein and negative regulator of actin polymerization. Cell Res (2011) 0.95
Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease. J Immunol (2014) 0.94
A mitotic recombination system for mouse chromosome 17. Proc Natl Acad Sci U S A (2008) 0.93
Clinical testing for the nevoid basal cell carcinoma syndrome in a DNA diagnostic laboratory. Genet Med (2005) 0.93
Roles for Drp1, a dynamin-related protein, and milton, a kinesin-associated protein, in mitochondrial segregation, unfurling and elongation during Drosophila spermatogenesis. Fly (Austin) (2007) 0.93
Indoor tanning and tanning dependence in young people after a diagnosis of basal cell carcinoma. JAMA Dermatol (2013) 0.92
Dissecting social cell biology and tumors using Drosophila genetics. Annu Rev Genet (2013) 0.92
A newly identified locus for benign adult familial myoclonic epilepsy on chromosome 3q26.32-3q28. Eur J Hum Genet (2012) 0.89
Adam10 is essential for early embryonic cardiovascular development. Dev Dyn (2010) 0.89
PDGFRa mutations in humans with isolated cleft palate. Eur J Hum Genet (2012) 0.88
Ablation of vacuole protein sorting 18 (Vps18) gene leads to neurodegeneration and impaired neuronal migration by disrupting multiple vesicle transport pathways to lysosomes. J Biol Chem (2012) 0.88
Molecular mechanism of size control in development and human diseases. Cell Res (2011) 0.88
Ubiquitous expression of mRFP1 in transgenic mice. Genesis (2005) 0.88
L63, the Drosophila PFTAIRE, interacts with two novel proteins unrelated to cyclins. Mech Dev (2003) 0.87
Disruption of lysosome function promotes tumor growth and metastasis in Drosophila. J Biol Chem (2010) 0.87
Nickel-catalyzed Suzuki-Miyaura reaction of aryl fluorides. J Am Chem Soc (2011) 0.87
Expression of Drosophila trehalose-phosphate synthase in HEK-293 cells increases hypoxia tolerance. J Biol Chem (2003) 0.87
Karyotype-phenotype insights from 11q14.1-q23.2 interstitial deletions: FZD4 haploinsufficiency and exudative vitreoretinopathy in a patient with a complex chromosome rearrangement. Am J Med Genet A (2006) 0.87
Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development. Dev Dyn (2010) 0.87
Low frequency of recurrent BRCA1 and BRCA2 mutations in Spain. Hum Mutat (2002) 0.87
A genetic screen for synaptic transmission mutants mapping to the right arm of chromosome 3 in Drosophila. Genetics (2003) 0.86
Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye. BMC Dev Biol (2009) 0.86
Characterization of DNA damage-dependent cell cycle checkpoints in a menin-deficient model. DNA Repair (Amst) (2009) 0.85
Clinical testing for multiple endocrine neoplasia type 1 in a DNA diagnostic laboratory. Genet Med (2005) 0.85
Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell Melanoma Res (2014) 0.84
A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity. Obesity (Silver Spring) (2015) 0.84
Characterization of fluorescent eye markers for mammalian transgenic studies. PLoS One (2011) 0.84
Expanding clinical spectrum of non-autoimmune hyperthyroidism due to an activating germline mutation, p.M453T, in the thyrotropin receptor gene. Clin Endocrinol (Oxf) (2008) 0.84
Functional characterization of vasopressin receptor 2 mutations causing partial and complete congenital nephrogenic diabetes insipidus in Thai families. Horm Res Paediatr (2010) 0.84
Dlic1 deficiency impairs ciliogenesis of photoreceptors by destabilizing dynein. Cell Res (2013) 0.84
Hexameric GFP and mCherry reporters for the Drosophila GAL4, Q, and LexA transcription systems. Genetics (2014) 0.84
Hypertension, alcohol drinking and stroke incidence: a population-based prospective cohort study among inner Mongolians in China. J Hypertens (2014) 0.84
Analyzing the function of tumor suppressor genes using a Drosophila model. Methods Mol Biol (2003) 0.84
piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice. Dis Model Mech (2013) 0.83
Tea, coffee, and caffeine and early-onset basal cell carcinoma in a case-control study. Eur J Cancer Prev (2014) 0.83
Muscle atrophy in transgenic mice expressing a human TSC1 transgene. FEBS Lett (2006) 0.83
Expansion of the gateway multisite recombination cloning toolkit. PLoS One (2013) 0.83
Novel gene identified in an exome-wide association study of tanning dependence. Exp Dermatol (2014) 0.83