Published in J Biol Chem on August 31, 2004
Accurate discovery of expression quantitative trait loci under confounding from spurious and genuine regulatory hotspots. Genetics (2008) 3.66
Glucose signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2006) 3.16
Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase. EMBO J (2010) 1.76
Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae. Curr Genet (2010) 1.65
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae. FEMS Microbiol Rev (2014) 1.59
The G protein-coupled receptor Gpr1 and the Galpha protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans. Mol Biol Cell (2005) 1.38
The Ras/cAMP/protein kinase A pathway regulates glucose-dependent assembly of the vacuolar (H+)-ATPase in yeast. J Biol Chem (2008) 1.33
Magnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi. FEMS Microbiol Rev (2008) 1.33
Actin-induced hyperactivation of the Ras signaling pathway leads to apoptosis in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.30
The regulation of filamentous growth in yeast. Genetics (2012) 1.29
Except in every detail: comparing and contrasting G-protein signaling in Saccharomyces cerevisiae and Schizosaccharomyces pombe. Eukaryot Cell (2005) 1.16
Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast. Cell Res (2012) 1.04
Regulation of pol III transcription by nutrient and stress signaling pathways. Biochim Biophys Acta (2012) 1.04
The RasGAP proteins Ira2 and neurofibromin are negatively regulated by Gpb1 in yeast and ETEA in humans. Mol Cell Biol (2010) 1.03
Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast. J Cell Sci (2009) 1.03
Glucose signaling-mediated coordination of cell growth and cell cycle in Saccharomyces cerevisiae. Sensors (Basel) (2010) 1.01
Loss of mitochondrial membrane potential triggers the retrograde response extending yeast replicative lifespan. Front Genet (2012) 1.00
Glucose sensing network in Candida albicans: a sweet spot for fungal morphogenesis. Eukaryot Cell (2009) 0.97
Deterministic mathematical models of the cAMP pathway in Saccharomyces cerevisiae. BMC Syst Biol (2009) 0.86
Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase. Genetics (2006) 0.84
Sir-dependent downregulation of various aging processes. Mol Genet Genomics (2005) 0.84
Protein kinase A and fungal virulence: a sinister side to a conserved nutrient sensing pathway. Virulence (2012) 0.83
Yeast glucose pathways converge on the transcriptional regulation of trehalose biosynthesis. BMC Genomics (2012) 0.82
The role of feedback control mechanisms on the establishment of oscillatory regimes in the Ras/cAMP/PKA pathway in S. cerevisiae. EURASIP J Bioinform Syst Biol (2012) 0.82
Transcriptional responses to glucose in Saccharomyces cerevisiae strains lacking a functional protein kinase A. BMC Genomics (2011) 0.81
Ras-Mediated Signal Transduction and Virulence in Human Pathogenic Fungi. Fungal Genom Biol (2012) 0.80
Protein kinase A is part of a mechanism that regulates nuclear reimport of the nuclear tRNA export receptors Los1p and Msn5p. Eukaryot Cell (2013) 0.80
Nutrient sensing kinases PKA and Sch9 phosphorylate the catalytic domain of the ubiquitin-conjugating enzyme Cdc34. PLoS One (2011) 0.79
The cAMP pathway is important for controlling the morphological switch to the pathogenic yeast form of Paracoccidioides brasiliensis. Mol Microbiol (2007) 0.79
Coordinate responses to alkaline pH stress in budding yeast. Microb Cell (2015) 0.78
Low concentrations of hydrogen peroxide or nitrite induced of Paracoccidioides brasiliensis cell proliferation in a Ras-dependent manner. PLoS One (2013) 0.78
Lack of HXK2 induces localization of active Ras in mitochondria and triggers apoptosis in the yeast Saccharomyces cerevisiae. Oxid Med Cell Longev (2013) 0.78
Quercetin protects Saccharomyces cerevisiae against oxidative stress by inducing trehalose biosynthesis and the cell wall integrity pathway. PLoS One (2012) 0.77
Ste50 adaptor protein influences Ras/cAMP-driven stress-response and cell survival in Saccharomyces cerevisiae. Curr Genet (2007) 0.77
Nuclear Ras2-GTP controls invasive growth in Saccharomyces cerevisiae. PLoS One (2013) 0.76
Modeling mutant phenotypes and oscillatory dynamics in the Saccharomyces cerevisiae cAMP-PKA pathway. BMC Syst Biol (2013) 0.75
The low affinity glucose transporter HxtB is also involved in glucose signalling and metabolism in Aspergillus nidulans. Sci Rep (2017) 0.75
Model-guided optogenetic study of PKA signaling in budding yeast. Mol Biol Cell (2016) 0.75
Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras. Nat Commun (2017) 0.75
A central integrator of transcription networks in plant stress and energy signalling. Nature (2007) 5.05
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. Nat Genet (2006) 3.04
Glucose-sensing and -signalling mechanisms in yeast. FEMS Yeast Res (2002) 2.50
TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0. Mol Cell (2003) 2.18
Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase. EMBO J (2010) 1.76
The Arabidopsis trehalose-6-P synthase AtTPS1 gene is a regulator of glucose, abscisic acid, and stress signaling. Plant Physiol (2004) 1.71
Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol (2003) 1.69
PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability. Mol Microbiol (2005) 1.69
Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae. Curr Genet (2010) 1.65
Inferring transcriptional modules from ChIP-chip, motif and microarray data. Genome Biol (2006) 1.64
The eukaryotic plasma membrane as a nutrient-sensing device. Trends Biochem Sci (2004) 1.63
Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae. FEMS Microbiol Rev (2014) 1.59
Glucose and sucrose act as agonist and mannose as antagonist ligands of the G protein-coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae. Mol Cell (2004) 1.58
The novel yeast PAS kinase Rim 15 orchestrates G0-associated antioxidant defense mechanisms. Cell Cycle (2004) 1.57
Expression levels of the yeast alcohol acetyltransferase genes ATF1, Lg-ATF1, and ATF2 control the formation of a broad range of volatile esters. Appl Environ Microbiol (2003) 1.56
Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis. Genome Res (2012) 1.46
Rim15 and the crossroads of nutrient signalling pathways in Saccharomyces cerevisiae. Cell Div (2006) 1.45
The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae. Mol Microbiol (2003) 1.44
Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains. Appl Environ Microbiol (2002) 1.42
Flavor-active esters: adding fruitiness to beer. J Biosci Bioeng (2003) 1.39
The G protein-coupled receptor Gpr1 and the Galpha protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans. Mol Biol Cell (2005) 1.38
The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity. J Biol Chem (2005) 1.34
Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast. Mol Microbiol (2006) 1.33
Disruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation. Infect Immun (2002) 1.33
Functional mitochondria are required for alpha-synuclein toxicity in aging yeast. J Biol Chem (2008) 1.28
The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution. Mol Cell Biol (2005) 1.27
A new nerve growth factor-mimetic peptide active on neuropathic pain in rats. J Neurosci (2008) 1.25
Yeast as a model for medical and medicinal research. Trends Pharmacol Sci (2005) 1.21
The AMPK/SNF1/SnRK1 fuel gauge and energy regulator: structure, function and regulation. FEBS J (2011) 1.20
Mitochondrial dysfunction leads to reduced chronological lifespan and increased apoptosis in yeast. FEBS Lett (2008) 1.17
A short regulatory domain restricts glycerol transport through yeast Fps1p. J Biol Chem (2002) 1.17
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nat Chem Biol (2008) 1.16
Phosphorylation, lipid raft interaction and traffic of alpha-synuclein in a yeast model for Parkinson. Biochim Biophys Acta (2008) 1.15
Why do microorganisms have aquaporins? Trends Microbiol (2006) 1.15
Production and biological function of volatile esters in Saccharomyces cerevisiae. Microb Biotechnol (2009) 1.15
Transport and signaling through the phosphate-binding site of the yeast Pho84 phosphate transceptor. Proc Natl Acad Sci U S A (2010) 1.14
Molecular mechanisms controlling the localisation of protein kinase A. Curr Genet (2002) 1.14
Multi-level response of the yeast genome to glucose. Genome Biol (2003) 1.12
Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco. Proc Natl Acad Sci U S A (2011) 1.12
Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast. Proc Natl Acad Sci U S A (2006) 1.11
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies. Acta Neuropathol Commun (2014) 1.09
Truncation of Arabidopsis thaliana and Selaginella lepidophylla trehalose-6-phosphate synthase unlocks high catalytic activity and supports high trehalose levels on expression in yeast. Biochem J (2002) 1.08
QTL analysis of high thermotolerance with superior and downgraded parental yeast strains reveals new minor QTLs and converges on novel causative alleles involved in RNA processing. PLoS Genet (2013) 1.08
Structure, expression, and functional analysis of the hexokinase gene family in rice (Oryza sativa L.). Planta (2006) 1.05
ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown. Plant Mol Biol (2006) 1.05
Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Mol Microbiol (2002) 1.05
Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast. Cell Res (2012) 1.04
Extensive expression regulation and lack of heterologous enzymatic activity of the Class II trehalose metabolism proteins from Arabidopsis thaliana. Plant Cell Environ (2009) 1.04
Genetic mapping of quantitative phenotypic traits in Saccharomyces cerevisiae. FEMS Yeast Res (2012) 1.03
Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast. J Cell Sci (2009) 1.03
A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential. Biochim Biophys Acta (2005) 1.03
Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae Tps1 mutants expressing trehalose-6-phosphate-insensitive hexokinase from Schizosaccharomyces pombe. Biochim Biophys Acta (2003) 1.03
Isolation and characterization of a freeze-tolerant diploid derivative of an industrial baker's yeast strain and its use in frozen doughs. Appl Environ Microbiol (2002) 1.03
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease. EMBO J (2013) 1.02
Comparative polygenic analysis of maximal ethanol accumulation capacity and tolerance to high ethanol levels of cell proliferation in yeast. PLoS Genet (2013) 1.01
Saccharomyces cerevisiae plasma membrane nutrient sensors and their role in PKA signaling. FEMS Yeast Res (2009) 1.00
Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast. FEBS J (2005) 1.00
Feedback inhibition on cell wall integrity signaling by Zds1 involves Gsk3 phosphorylation of a cAMP-dependent protein kinase regulatory subunit. J Biol Chem (2003) 1.00
The protein quality control system manages plant defence compound synthesis. Nature (2013) 0.99
Isolation and characterization of brewer's yeast variants with improved fermentation performance under high-gravity conditions. Appl Environ Microbiol (2006) 0.99
The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae. Mol Biol Cell (2013) 0.97
Ceramide involvement in apoptosis and apoptotic diseases. Mini Rev Med Chem (2006) 0.97
Functional analysis of RalGPS2, a murine guanine nucleotide exchange factor for RalA GTPase. Exp Cell Res (2007) 0.97
Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum. Proc Natl Acad Sci U S A (2014) 0.96
Segregation of protein aggregates involves actin and the polarity machinery. Cell (2011) 0.96
Molecular mechanisms of feedback inhibition of protein kinase A on intracellular cAMP accumulation. Cell Signal (2012) 0.96
A bifunctional TPS-TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis. Planta (2007) 0.96
Identification and isolation of a hyperphosphorylated, conformationally changed intermediate of human protein tau expressed in yeast. Biochemistry (2005) 0.95
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy (2012) 0.95
Analysis of the gene expression profile of mouse male meiotic germ cells. Gene Expr Patterns (2004) 0.95
Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro. New Phytol (2013) 0.95
The Saccharomyces cerevisiae alcohol acetyl transferase Atf1p is localized in lipid particles. Yeast (2004) 0.95
Combining inhibitor tolerance and D-xylose fermentation in industrial Saccharomyces cerevisiae for efficient lignocellulose-based bioethanol production. Biotechnol Biofuels (2013) 0.95
Attenuation of chronic neuroinflammation by a nitric oxide-releasing derivative of the antioxidant ferulic acid. J Neurochem (2004) 0.94
Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry (2009) 0.94
An integrated framework for discovery and genotyping of genomic variants from high-throughput sequencing experiments. Nucleic Acids Res (2014) 0.94
Microtubule binding and clustering of human Tau-4R and Tau-P301L proteins isolated from yeast deficient in orthologues of glycogen synthase kinase-3beta or cdk5. J Biol Chem (2006) 0.94
Yeast nutrient transceptors provide novel insight in the functionality of membrane transporters. Curr Genet (2013) 0.93
Cyclic AMP-protein kinase A and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in Saccharomyces cerevisiae. Eukaryot Cell (2007) 0.92
SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis. FEBS Lett (2005) 0.92
Determinants of freeze tolerance in microorganisms, physiological importance, and biotechnological applications. Adv Appl Microbiol (2003) 0.91
Glucose and sucrose: hazardous fast-food for industrial yeast? Trends Biotechnol (2004) 0.91
Modeling and stochastic simulation of the Ras/cAMP/PKA pathway in the yeast Saccharomyces cerevisiae evidences a key regulatory function for intracellular guanine nucleotides pools. J Biotechnol (2007) 0.91
Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H(+) transceptor and its effect on signalling to the PKA and PHO pathways. Biochem J (2012) 0.90
Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae. FEMS Yeast Res (2013) 0.90
Phenotypic evaluation of natural and industrial Saccharomyces yeasts for different traits desirable in industrial bioethanol production. Appl Microbiol Biotechnol (2014) 0.89
Peptides induce persistent signaling from endosomes by a nutrient transceptor. Nat Chem Biol (2012) 0.89
Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9. FEMS Yeast Res (2008) 0.89
Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast. FEBS Lett (2006) 0.89
The deubiquitinating enzyme mUBPy interacts with the sperm-specific molecular chaperone MSJ-1: the relation with the proteasome, acrosome, and centrosome in mouse male germ cells. Biol Reprod (2004) 0.89
Glucose-induced calcium influx in budding yeast involves a novel calcium transport system and can activate calcineurin. Cell Calcium (2011) 0.89