Published in Proc Natl Acad Sci U S A on February 01, 2010
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Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis. J Biol Chem (2010) 0.93
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Phosphate and succinate use different mechanisms to inhibit sugar-induced cell death in yeast: insight into the Crabtree effect. J Biol Chem (2011) 0.82
A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine. Mol Genet Genomics (2011) 0.82
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Identification of Ftr1 and Zrt1 as iron and zinc micronutrient transceptors for activation of the PKA pathway in Saccharomyces cerevisiae. Microb Cell (2017) 0.75
Achieving global perfect homeostasis through transporter regulation. PLoS Comput Biol (2017) 0.75
A novel approach using C. elegans DNA damage-induced apoptosis to characterize the dynamics of uptake transporters for therapeutic drug discoveries. Sci Rep (2016) 0.75
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Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol (2003) 1.69
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The Mep2p ammonium permease controls nitrogen starvation-induced filamentous growth in Candida albicans. Mol Microbiol (2005) 1.50
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Competitive intra- and extracellular nutrient sensing by the transporter homologue Ssy1p. J Cell Biol (2006) 1.38
Nitrate signalling mediated by the NRT1.1 nitrate transporter antagonises L-glutamate-induced changes in root architecture. Plant J (2008) 1.37
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GIT1, a gene encoding a novel transporter for glycerophosphoinositol in Saccharomyces cerevisiae. Genetics (1998) 1.18
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nat Chem Biol (2008) 1.16
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Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry (2009) 0.94
Glycerophosphoinositol, a novel phosphate source whose transport is regulated by multiple factors in Saccharomyces cerevisiae. J Biol Chem (2004) 0.91
A central integrator of transcription networks in plant stress and energy signalling. Nature (2007) 5.05
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. Nat Genet (2006) 3.04
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The Arabidopsis trehalose-6-P synthase AtTPS1 gene is a regulator of glucose, abscisic acid, and stress signaling. Plant Physiol (2004) 1.71
Inorganic phosphate is sensed by specific phosphate carriers and acts in concert with glucose as a nutrient signal for activation of the protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol (2003) 1.69
PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability. Mol Microbiol (2005) 1.69
The eukaryotic plasma membrane as a nutrient-sensing device. Trends Biochem Sci (2004) 1.63
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Glucose and sucrose act as agonist and mannose as antagonist ligands of the G protein-coupled receptor Gpr1 in the yeast Saccharomyces cerevisiae. Mol Cell (2004) 1.58
Expression levels of the yeast alcohol acetyltransferase genes ATF1, Lg-ATF1, and ATF2 control the formation of a broad range of volatile esters. Appl Environ Microbiol (2003) 1.56
Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis. Genome Res (2012) 1.46
The Gap1 general amino acid permease acts as an amino acid sensor for activation of protein kinase A targets in the yeast Saccharomyces cerevisiae. Mol Microbiol (2003) 1.44
Aquaporin expression correlates with freeze tolerance in baker's yeast, and overexpression improves freeze tolerance in industrial strains. Appl Environ Microbiol (2002) 1.42
Flavor-active esters: adding fruitiness to beer. J Biosci Bioeng (2003) 1.39
The G protein-coupled receptor Gpr1 and the Galpha protein Gpa2 act through the cAMP-protein kinase A pathway to induce morphogenesis in Candida albicans. Mol Biol Cell (2005) 1.38
The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity. J Biol Chem (2005) 1.34
Ammonium permease-based sensing mechanism for rapid ammonium activation of the protein kinase A pathway in yeast. Mol Microbiol (2006) 1.33
Disruption of the Candida albicans TPS2 gene encoding trehalose-6-phosphate phosphatase decreases infectivity without affecting hypha formation. Infect Immun (2002) 1.33
Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae. J Biol Chem (2004) 1.22
A short regulatory domain restricts glycerol transport through yeast Fps1p. J Biol Chem (2002) 1.17
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor. Nat Chem Biol (2008) 1.16
Why do microorganisms have aquaporins? Trends Microbiol (2006) 1.15
Production and biological function of volatile esters in Saccharomyces cerevisiae. Microb Biotechnol (2009) 1.15
Molecular mechanisms controlling the localisation of protein kinase A. Curr Genet (2002) 1.14
Multi-level response of the yeast genome to glucose. Genome Biol (2003) 1.12
Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco. Proc Natl Acad Sci U S A (2011) 1.12
Kelch-repeat proteins interacting with the Galpha protein Gpa2 bypass adenylate cyclase for direct regulation of protein kinase A in yeast. Proc Natl Acad Sci U S A (2006) 1.11
Truncation of Arabidopsis thaliana and Selaginella lepidophylla trehalose-6-phosphate synthase unlocks high catalytic activity and supports high trehalose levels on expression in yeast. Biochem J (2002) 1.08
QTL analysis of high thermotolerance with superior and downgraded parental yeast strains reveals new minor QTLs and converges on novel causative alleles involved in RNA processing. PLoS Genet (2013) 1.08
ABI4 mediates the effects of exogenous trehalose on Arabidopsis growth and starch breakdown. Plant Mol Biol (2006) 1.05
Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Mol Microbiol (2002) 1.05
Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast. Cell Res (2012) 1.04
Extensive expression regulation and lack of heterologous enzymatic activity of the Class II trehalose metabolism proteins from Arabidopsis thaliana. Plant Cell Environ (2009) 1.04
Isolation and characterization of a freeze-tolerant diploid derivative of an industrial baker's yeast strain and its use in frozen doughs. Appl Environ Microbiol (2002) 1.03
Uncoupling of the glucose growth defect and the deregulation of glycolysis in Saccharomyces cerevisiae Tps1 mutants expressing trehalose-6-phosphate-insensitive hexokinase from Schizosaccharomyces pombe. Biochim Biophys Acta (2003) 1.03
Genetic mapping of quantitative phenotypic traits in Saccharomyces cerevisiae. FEMS Yeast Res (2012) 1.03
Comparative polygenic analysis of maximal ethanol accumulation capacity and tolerance to high ethanol levels of cell proliferation in yeast. PLoS Genet (2013) 1.01
Saccharomyces cerevisiae plasma membrane nutrient sensors and their role in PKA signaling. FEMS Yeast Res (2009) 1.00
Feedback inhibition on cell wall integrity signaling by Zds1 involves Gsk3 phosphorylation of a cAMP-dependent protein kinase regulatory subunit. J Biol Chem (2003) 1.00
The protein quality control system manages plant defence compound synthesis. Nature (2013) 0.99
Isolation and characterization of brewer's yeast variants with improved fermentation performance under high-gravity conditions. Appl Environ Microbiol (2006) 0.99
Combinatorial biosynthesis of sapogenins and saponins in Saccharomyces cerevisiae using a C-16α hydroxylase from Bupleurum falcatum. Proc Natl Acad Sci U S A (2014) 0.96
Molecular mechanisms of feedback inhibition of protein kinase A on intracellular cAMP accumulation. Cell Signal (2012) 0.96
A bifunctional TPS-TPP enzyme from yeast confers tolerance to multiple and extreme abiotic-stress conditions in transgenic Arabidopsis. Planta (2007) 0.96
Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro. New Phytol (2013) 0.95
The Saccharomyces cerevisiae alcohol acetyl transferase Atf1p is localized in lipid particles. Yeast (2004) 0.95
Combining inhibitor tolerance and D-xylose fermentation in industrial Saccharomyces cerevisiae for efficient lignocellulose-based bioethanol production. Biotechnol Biofuels (2013) 0.95
An integrated framework for discovery and genotyping of genomic variants from high-throughput sequencing experiments. Nucleic Acids Res (2014) 0.94
Molecular mechanisms controlling phosphate-induced downregulation of the yeast Pho84 phosphate transporter. Biochemistry (2009) 0.94
Yeast nutrient transceptors provide novel insight in the functionality of membrane transporters. Curr Genet (2013) 0.93
Cyclic AMP-protein kinase A and Snf1 signaling mechanisms underlie the superior potency of sucrose for induction of filamentation in Saccharomyces cerevisiae. Eukaryot Cell (2007) 0.92
Determinants of freeze tolerance in microorganisms, physiological importance, and biotechnological applications. Adv Appl Microbiol (2003) 0.91
TrkA pathway activation induced by amyloid-beta (Abeta). Mol Cell Neurosci (2008) 0.91
Glucose and sucrose: hazardous fast-food for industrial yeast? Trends Biotechnol (2004) 0.91
Prion protein structure is affected by pH-dependent interaction with membranes: a study in a model system. FEBS Lett (2007) 0.90
Mutational analysis of putative phosphate- and proton-binding sites in the Saccharomyces cerevisiae Pho84 phosphate:H(+) transceptor and its effect on signalling to the PKA and PHO pathways. Biochem J (2012) 0.90
Phenotypic evaluation of natural and industrial Saccharomyces yeasts for different traits desirable in industrial bioethanol production. Appl Microbiol Biotechnol (2014) 0.89
Peptides induce persistent signaling from endosomes by a nutrient transceptor. Nat Chem Biol (2012) 0.89
The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways. FEMS Yeast Res (2003) 0.88
Yeast 3-phosphoinositide-dependent protein kinase-1 (PDK1) orthologs Pkh1-3 differentially regulate phosphorylation of protein kinase A (PKA) and the protein kinase B (PKB)/S6K ortholog Sch9. J Biol Chem (2011) 0.87
Aquaporin-mediated improvement of freeze tolerance of Saccharomyces cerevisiae is restricted to rapid freezing conditions. Appl Environ Microbiol (2004) 0.87
The trehalose pathway regulates mitochondrial respiratory chain content through hexokinase 2 and cAMP in Saccharomyces cerevisiae. J Biol Chem (2009) 0.85
Characterization of the Pho89 phosphate transporter by functional hyperexpression in Saccharomyces cerevisiae. FEMS Yeast Res (2008) 0.85
Directly from Galpha to protein kinase A: the kelch repeat protein bypass of adenylate cyclase. Trends Biochem Sci (2007) 0.85
Novel mechanisms in nutrient activation of the yeast protein kinase A pathway. Acta Microbiol Immunol Hung (2008) 0.85
A split-ubiquitin two-hybrid screen for proteins physically interacting with the yeast amino acid transceptor Gap1 and ammonium transceptor Mep2. PLoS One (2011) 0.85
Evidence for inositol triphosphate as a second messenger for glucose-induced calcium signalling in budding yeast. Curr Genet (2003) 0.85
Identification of hexose transporter-like sensor HXS1 and functional hexose transporter HXT1 in the methylotrophic yeast Hansenula polymorpha. Eukaryot Cell (2008) 0.85
In vivo phosphorylation of Ser21 and Ser83 during nutrient-induced activation of the yeast protein kinase A (PKA) target trehalase. J Biol Chem (2012) 0.85
Aβ42 production in brain capillary endothelial cells after oxygen and glucose deprivation. Mol Cell Neurosci (2012) 0.85
Quantitative trait analysis of yeast biodiversity yields novel gene tools for metabolic engineering. Metab Eng (2013) 0.84
Specific analogues uncouple transport, signalling, oligo-ubiquitination and endocytosis in the yeast Gap1 amino acid transceptor. Mol Microbiol (2014) 0.84
Agp2, a member of the yeast amino acid permease family, positively regulates polyamine transport at the transcriptional level. PLoS One (2013) 0.83
Identification of multiple interacting alleles conferring low glycerol and high ethanol yield in Saccharomyces cerevisiae ethanolic fermentation. Biotechnol Biofuels (2013) 0.83
Combined inactivation of the Candida albicans GPR1 and TPS2 genes results in avirulence in a mouse model for systemic infection. Infect Immun (2008) 0.82
G-protein-coupled receptor Gpr1 and G-protein Gpa2 of cAMP-dependent signaling pathway are involved in glucose-induced pexophagy in the yeast Saccharomyces cerevisiae. Cell Biol Int (2007) 0.82
Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains. Appl Microbiol Biotechnol (2007) 0.81
Controlled expression of homologous genes by genomic promoter replacement in the yeast Saccharomyces cerevisiae. Methods Mol Biol (2004) 0.81
Natural and modified promoters for tailored metabolic engineering of the yeast Saccharomyces cerevisiae. Methods Mol Biol (2014) 0.81
Trehalose-6-phosphate synthase as an intrinsic selection marker for plant transformation. J Biotechnol (2005) 0.81
Flavour formation in fungi: characterisation of KlAtf, the Kluyveromyces lactis orthologue of the Saccharomyces cerevisiae alcohol acetyltransferases Atf1 and Atf2. Appl Microbiol Biotechnol (2008) 0.81
Aquaporin expression and freeze tolerance in Candida albicans. Appl Environ Microbiol (2005) 0.81
Evidence for rapid uptake of D-galacturonic acid in the yeast Saccharomyces cerevisiae by a channel-type transport system. FEBS Lett (2012) 0.81
Pin1 affects Tau phosphorylation in response to Abeta oligomers. Mol Cell Neurosci (2009) 0.80
Characterization of a recombinant bifunctional xylosidase/arabinofuranosidase from Phanerochaete chrysosporium. J Biosci Bioeng (2013) 0.80
Assessing the potential of wild yeasts for bioethanol production. J Ind Microbiol Biotechnol (2014) 0.79
Activation state of protein kinase A as measured in permeabilised Saccharomyces cerevisiae cells correlates with PKA-controlled phenotypes in vivo. FEMS Yeast Res (2003) 0.79
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The activation loop of PKA catalytic isoforms is differentially phosphorylated by Pkh protein kinases in Saccharomyces cerevisiae. Biochem J (2012) 0.78
Heterologous aquaporin (AQY2-1) expression strongly enhances freeze tolerance of Schizosaccharomyces pombe. J Mol Microbiol Biotechnol (2005) 0.78
Differences in glucose sensing and signaling for pexophagy between the baker's yeast Saccharomyces cerevisiae and the methylotrophic yeast Pichia pastoris. Autophagy (2008) 0.77
Enhanced folate binding of cultured fibroblasts from Alzheimer's disease patients. Neurosci Lett (2008) 0.77
QTL mapping by pooled-segregant whole-genome sequencing in yeast. Methods Mol Biol (2014) 0.77
The Saccharomyces cerevisiae type 2A protein phosphatase Pph22p is biochemically different from mammalian PP2A. Eur J Biochem (2002) 0.76
Mammalian ribosomal and chaperone protein RPS3A counteracts α-synuclein aggregation and toxicity in a yeast model system. Biochem J (2013) 0.76
Abeta peptide toxicity is reduced after treatments decreasing phosphatidylethanolamine content in differentiated neuroblastoma cells. Neurochem Res (2011) 0.76
New selection marker for plant transformation. Methods Mol Biol (2004) 0.75