PubRank

Anne J Ridley

Author PubWeight™ 147.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 2008 8.99
2 Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 2003 8.68
3 Rho GTPases in cancer cell biology. FEBS Lett 2008 4.47
4 Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. Nature 2008 3.19
5 Lymphocyte transcellular migration occurs through recruitment of endothelial ICAM-1 to caveola- and F-actin-rich domains. Nat Cell Biol 2006 3.08
6 Rho GTPases and the regulation of endothelial permeability. Vascul Pharmacol 2002 2.88
7 Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res 2004 2.83
8 RhoA and RhoC have distinct roles in migration and invasion by acting through different targets. J Cell Biol 2011 2.59
9 RhoE binds to ROCK I and inhibits downstream signaling. Mol Cell Biol 2003 2.46
10 Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron 2011 2.42
11 Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J Cell Biol 2003 2.14
12 Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability. J Cell Physiol 2007 2.03
13 Crossing the endothelial barrier during metastasis. Nat Rev Cancer 2013 2.00
14 Phosphoinositide 3-kinases in cell migration. Biol Cell 2009 1.95
15 14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins. Cell 2013 1.90
16 Rac1-deficient macrophages exhibit defects in cell spreading and membrane ruffling but not migration. J Cell Sci 2004 1.88
17 Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein. J Biol Chem 2002 1.88
18 Ezrin/radixin/moesin proteins and Rho GTPase signalling in leucocytes. Immunology 2004 1.82
19 IQGAP1 promotes cell motility and invasion. J Biol Chem 2003 1.72
20 Rac1 and Rac2 regulate macrophage morphology but are not essential for migration. J Cell Sci 2006 1.70
21 Differential regulation of phagosome maturation in macrophages and dendritic cells mediated by Rho GTPases and ezrin-radixin-moesin (ERM) proteins. Proc Natl Acad Sci U S A 2006 1.64
22 Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis. Cancer Res 2002 1.63
23 RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J 2005 1.59
24 Phosphorylation of the WASP-VCA domain increases its affinity for the Arp2/3 complex and enhances actin polymerization by WASP. Mol Cell 2003 1.53
25 Adherens junctions connect stress fibres between adjacent endothelial cells. BMC Biol 2010 1.52
26 Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells. PLoS One 2010 1.49
27 The p110delta isoform of PI 3-kinase negatively controls RhoA and PTEN. EMBO J 2007 1.48
28 RhoE inhibits cell cycle progression and Ras-induced transformation. Mol Cell Biol 2004 1.41
29 Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages. J Cell Sci 2008 1.39
30 RhoE is a pro-survival p53 target gene that inhibits ROCK I-mediated apoptosis in response to genotoxic stress. Curr Biol 2006 1.37
31 Rho GTPases and leukocyte adhesion receptor expression and function in endothelial cells. Circ Res 2006 1.35
32 Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration. J Cell Biol 2010 1.35
33 Endothelial intercellular adhesion molecule (ICAM)-2 regulates angiogenesis. Blood 2005 1.34
34 PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics. J Cell Sci 2008 1.32
35 Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration. BMC Biol 2011 1.30
36 The PI3K p110alpha isoform regulates endothelial adherens junctions via Pyk2 and Rac1. J Cell Biol 2010 1.28
37 Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure. EMBO J 2008 1.27
38 Intercellular adhesion molecule (ICAM)-1, but not ICAM-2, activates RhoA and stimulates c-fos and rhoA transcription in endothelial cells. J Immunol 2002 1.25
39 Requirement for PI 3-kinase gamma in macrophage migration to MCP-1 and CSF-1. Exp Cell Res 2003 1.25
40 PAK4 is activated via PI3K in HGF-stimulated epithelial cells. J Cell Sci 2002 1.24
41 Cell migration in development and disease. Dev Cell 2002 1.23
42 Rnd proteins: multifunctional regulators of the cytoskeleton and cell cycle progression. Bioessays 2010 1.21
43 Cdc42 promotes transendothelial migration of cancer cells through β1 integrin. J Cell Biol 2012 1.20
44 Involvement of phosphoinositide 3-kinase gamma, Rac, and PAK signaling in chemokine-induced macrophage migration. J Biol Chem 2004 1.20
45 Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation. Biochem J 2009 1.19
46 p120 catenin associates with microtubules: inverse relationship between microtubule binding and Rho GTPase regulation. J Biol Chem 2003 1.18
47 Implantation of the human embryo requires Rac1-dependent endometrial stromal cell migration. Proc Natl Acad Sci U S A 2008 1.17
48 Cell motility: braking WAVEs. Nature 2002 1.14
49 RhoB affects macrophage adhesion, integrin expression and migration. Exp Cell Res 2007 1.13
50 T cell receptor-induced phosphoinositide-3-kinase p110delta activity is required for T cell localization to antigenic tissue in mice. J Clin Invest 2008 1.13
51 Mutagenesis of the ezrin-radixin-moesin binding domain of L-selectin tail affects shedding, microvillar positioning, and leukocyte tethering. J Biol Chem 2004 1.12
52 Class I phosphoinositide 3-kinase p110beta is required for apoptotic cell and Fcgamma receptor-mediated phagocytosis by macrophages. J Biol Chem 2003 1.11
53 Extension, retraction and contraction in the formation of a dendritic cell dendrite: distinct roles for Rho GTPases. Eur J Immunol 2002 1.10
54 PAK1 and PAK2 have different roles in HGF-induced morphological responses. Cell Signal 2009 1.10
55 SnapShot: Rho family GTPases. Cell 2007 1.10
56 Rho GTPases and cell cycle control. Growth Factors 2006 1.08
57 The prostate-derived sterile 20-like kinase (PSK) regulates microtubule organization and stability. J Biol Chem 2003 1.08
58 Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms. Mol Biol Cell 2006 1.07
59 Rho GTPases and leucocyte-induced endothelial remodelling. Biochem J 2005 1.07
60 The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis. Blood 2011 1.07
61 Rac activation by the T-cell receptor inhibits T cell migration. PLoS One 2010 1.03
62 p120ctn and P-cadherin but not E-cadherin regulate cell motility and invasion of DU145 prostate cancer cells. PLoS One 2010 1.02
63 Radixin regulates cell migration and cell-cell adhesion through Rac1. J Cell Sci 2012 1.00
64 Analysis of cell migration using the Dunn chemotaxis chamber and time-lapse microscopy. Methods Mol Biol 2005 0.98
65 Transcriptional regulation of the small GTPase RhoB gene by TGF{beta}-induced signaling pathways. FASEB J 2009 0.95
66 Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1. J Biol Chem 2006 0.94
67 Crosstalk between reticular adherens junctions and platelet endothelial cell adhesion molecule-1 regulates endothelial barrier function. Arterioscler Thromb Vasc Biol 2012 0.94
68 Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization. Exp Cell Res 2005 0.94
69 CSF-1 and PI 3-kinase regulate podosome distribution and assembly in macrophages. Cell Motil Cytoskeleton 2006 0.93
70 Casein kinase I epsilon associates with and phosphorylates the tight junction protein occludin. FEBS Lett 2006 0.93
71 RhoB regulates cell migration through altered focal adhesion dynamics. Open Biol 2012 0.93
72 Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing. J Biol Chem 2006 0.92
73 RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation. J Biol Chem 2009 0.91
74 In Vitro and in Vivo Characterization of Molecular Interactions between Calmodulin, Ezrin/Radixin/Moesin, and L-selectin. J Biol Chem 2009 0.90
75 Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation. Exp Cell Res 2009 0.90
76 RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific. Circ Res 2004 0.89
77 T-cell receptor- and CD28-induced Vav1 activity is required for the accumulation of primed T cells into antigenic tissue. Blood 2008 0.89
78 Multiple roles for RhoA during T cell transendothelial migration. Small GTPases 2010 0.88
79 Crystal structure of the core domain of RhoE/Rnd3: a constitutively activated small G protein. Biochemistry 2002 0.88
80 Rho GTPases and cancer cell transendothelial migration. Methods Mol Biol 2012 0.88
81 Statins inhibit T-acute lymphoblastic leukemia cell adhesion and migration through Rap1b. J Leukoc Biol 2011 0.87
82 RhoB regulates uPAR signalling. J Cell Sci 2012 0.87
83 FMNL1 promotes proliferation and migration of leukemia cells. J Leukoc Biol 2013 0.87
84 beta1-Integrins determine the dendritic morphology which enhances DC-SIGN-mediated particle capture by dendritic cells. Int Immunol 2006 0.86
85 CD73 represses pro-inflammatory responses in human endothelial cells. J Inflamm (Lond) 2010 0.85
86 Human endometrial stromal cell rho GTPases have opposing roles in regulating focal adhesion turnover and embryo invasion in vitro. Biol Reprod 2010 0.85
87 Rnd3 induces stress fibres in endothelial cells through RhoB. Biol Open 2012 0.85
88 Inhibition of ROCK by RhoE. Methods Enzymol 2006 0.84
89 Quantification of transendothelial migration using three-dimensional confocal microscopy. Methods Mol Biol 2011 0.83
90 MYADM controls endothelial barrier function through ERM-dependent regulation of ICAM-1 expression. Mol Biol Cell 2012 0.83
91 ARHGAP21 is a RhoGAP for RhoA and RhoC with a role in proliferation and migration of prostate adenocarcinoma cells. Biochim Biophys Acta 2012 0.83
92 Effects of microinjected small GTPases on the actin cytoskeleton of human neutrophils. J Anat 2003 0.82
93 Getting invasive with GEP100 and Arf6. Nat Cell Biol 2008 0.82
94 Roles of Rho GTPases in leucocyte and leukaemia cell transendothelial migration. Philos Trans R Soc Lond B Biol Sci 2013 0.81
95 An in vitro model to study the role of endothelial rho GTPases during leukocyte transendothelial migration. Methods Enzymol 2006 0.80
96 Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration. Cytoskeleton (Hoboken) 2014 0.80
97 N-terminus-mediated dimerization of ROCK-I is required for RhoE binding and actin reorganization. Biochem J 2008 0.80
98 Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration. Int J Biochem Cell Biol 2012 0.79
99 Analyzing the roles of Rho GTPases in cancer cell migration with a live cell imaging 3D-morphology-based assay. Methods Mol Biol 2014 0.78
100 RhoE Is a Pro-Survival p53 Target Gene that Inhibits ROCK I-Mediated Apoptosis in Response to Genotoxic Stress. Curr Biol 2016 0.77
101 Using the Dunn chemotaxis chamber to analyze primary cell migration in real time. Methods Mol Biol 2011 0.77
102 Mammalian cell microinjection assay to study the function of Rho family guanosine triphosphatases. Methods Mol Biol 2006 0.76
103 Rho and Rap guanosine triphosphatase signaling in B cells and chronic lymphocytic leukemia. Leuk Lymphoma 2013 0.76
104 Focus on membrane dynamics. Trends Cell Biol 2006 0.75
105 Determining Rho GTPase activity by an affinity-precipitation assay. Methods Mol Biol 2013 0.75