Published in Mol Cell Biol on November 01, 2004
Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. Genetics (2012) 1.56
Evolutionary-conserved telomere-linked helicase genes of fission yeast are repressed by silencing factors, RNAi components and the telomere-binding protein Taz1. Nucleic Acids Res (2006) 1.23
5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotransposition. J Virol (2010) 1.17
Posttranslational interference of Ty1 retrotransposition by antisense RNAs. Proc Natl Acad Sci U S A (2009) 1.07
Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast. EMBO J (2009) 1.04
Retrosequence formation restructures the yeast genome. Genes Dev (2007) 1.00
Sgs1 RecQ helicase inhibits survival of Saccharomyces cerevisiae cells lacking telomerase and homologous recombination. J Biol Chem (2008) 0.95
Essential domains for ribonucleoprotein complex formation required for retrotransposition of telomere-specific non-long terminal repeat retrotransposon SART1. Mol Cell Biol (2006) 0.94
S-phase checkpoint pathways stimulate the mobility of the retrovirus-like transposon Ty1. Mol Cell Biol (2007) 0.93
Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retroviruses. Eukaryot Cell (2007) 0.92
Severe adenine starvation activates Ty1 transcription and retrotransposition in Saccharomyces cerevisiae. Mol Cell Biol (2005) 0.91
DNA repair at telomeres: keeping the ends intact. Cold Spring Harb Perspect Biol (2013) 0.89
The beginning of the end: links between ancient retroelements and modern telomerases. Proc Natl Acad Sci U S A (2007) 0.89
Origin and fate of pseudogenes in Hemiascomycetes: a comparative analysis. BMC Genomics (2010) 0.87
The Ty1 LTR-retrotransposon of budding yeast, Saccharomyces cerevisiae. Microbiol Spectr (2015) 0.86
Environment-responsive transcription factors bind subtelomeric elements and regulate gene silencing. Mol Syst Biol (2011) 0.85
Extension of Saccharomyces paradoxus chronological lifespan by retrotransposons in certain media conditions is associated with changes in reactive oxygen species. Genetics (2014) 0.85
Co-translational localization of an LTR-retrotransposon RNA to the endoplasmic reticulum nucleates virus-like particle assembly sites. PLoS Genet (2014) 0.81
Host co-factors of the retrovirus-like transposon Ty1. Mob DNA (2012) 0.81
Multiple Mechanisms Contribute To Telomere Maintenance. J Cancer Biol Res (2013) 0.80
Incorporation of Y'-Ty1 cDNA destabilizes telomeres in Saccharomyces cerevisiae telomerase-negative mutants. Genetics (2008) 0.76
If the cap fits, wear it: an overview of telomeric structures over evolution. Cell Mol Life Sci (2013) 0.76
Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance. Front Genet (2016) 0.75
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics (1989) 105.30
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (1999) 36.25
Genome-wide expression monitoring in Saccharomyces cerevisiae. Nat Biotechnol (1997) 27.78
Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast (1998) 23.00
Switching and signaling at the telomere. Cell (2001) 11.25
Ty elements transpose through an RNA intermediate. Cell (1985) 9.56
TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science (1994) 9.08
A mutant with a defect in telomere elongation leads to senescence in yeast. Cell (1989) 8.69
LINE-mediated retrotransposition of marked Alu sequences. Nat Genet (2003) 7.32
An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell (1993) 6.89
Human LINE retrotransposons generate processed pseudogenes. Nat Genet (2000) 6.64
Organization of DNA sequences and replication origins at yeast telomeres. Cell (1983) 6.43
Saccharomyces Genome Database (SGD) provides biochemical and structural information for budding yeast proteins. Nucleic Acids Res (2003) 5.69
Telomeres and their control. Annu Rev Genet (2000) 4.74
The DNA intermediate in yeast Ty1 element transposition copurifies with virus-like particles: cell-free Ty1 transposition. Cell (1988) 3.83
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol (1999) 3.79
Maturation of dimeric viral RNA of Moloney murine leukemia virus. J Virol (1993) 3.78
The chromosome ends of Saccharomyces cerevisiae. Yeast (1995) 3.60
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55
Single-step selection for Ty1 element retrotransposition. Proc Natl Acad Sci U S A (1991) 3.29
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity. Proc Natl Acad Sci U S A (1997) 3.11
Multiple regulators of Ty1 transposition in Saccharomyces cerevisiae have conserved roles in genome maintenance. Genetics (2001) 3.10
The structure and evolution of subtelomeric Y' repeats in Saccharomyces cerevisiae. Genetics (1992) 2.96
Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process. Mol Cell (2000) 2.76
Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev (1996) 2.76
Telomere dysfunction increases mutation rate and genomic instability. Cell (2001) 2.62
Two modes of survival of fission yeast without telomerase. Science (1998) 2.57
Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events. Mol Cell Biol (2001) 2.34
Structure, function, and replication of Saccharomyces cerevisiae telomeres. Annu Rev Genet (1996) 2.32
Temperature effects on the rate of ty transposition. Science (1984) 2.27
Propagation and expression of cloned genes in yeast: 2-microns circle-based vectors. Methods Enzymol (1990) 2.14
RNA-mediated recombination in S. cerevisiae. Cell (1991) 1.96
Short telomeres induce a DNA damage response in Saccharomyces cerevisiae. Mol Biol Cell (2003) 1.86
Ty RNA levels determine the spectrum of retrotransposition events that activate gene expression in Saccharomyces cerevisiae. Mol Gen Genet (1990) 1.84
Indecent exposure: when telomeres become uncapped. Mol Cell (2004) 1.82
TEC1, a gene involved in the activation of Ty1 and Ty1-mediated gene expression in Saccharomyces cerevisiae: cloning and molecular analysis. Mol Cell Biol (1990) 1.52
MEC3, MEC1, and DDC2 are essential components of a telomere checkpoint pathway required for cell cycle arrest during senescence in Saccharomyces cerevisiae. Mol Biol Cell (2002) 1.48
The reverse transcriptase of the R2 non-LTR retrotransposon: continuous synthesis of cDNA on non-continuous RNA templates. J Mol Biol (2002) 1.45
Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem (1998) 1.24
Identification of autonomously replicating circular subtelomeric Y' elements in Saccharomyces cerevisiae. Mol Cell Biol (1985) 1.21
Reverse transcription of retroviruses and LTR retrotransposons. Cell Mol Life Sci (2001) 1.18
The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays. Mol Cell Biol (2001) 1.10
Activation of a LTR-retrotransposon by telomere erosion. Proc Natl Acad Sci U S A (2003) 1.09
Recovery of a function involving gene duplication by retroposition in Saccharomyces cerevisiae. Genome Res (2004) 1.09
The involvement of cellular recombination and repair genes in RNA-mediated recombination in Saccharomyces cerevisiae. Genetics (1998) 1.00
Ty1 defect in proteolysis at high temperature. J Virol (2002) 0.94
Functional profiling of the Saccharomyces cerevisiae genome. Nature (2002) 36.10
Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets. Nat Genet (2006) 6.74
A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell (2006) 6.61
Transcriptional disruption by the L1 retrotransposon and implications for mammalian transcriptomes. Nature (2004) 5.15
Human l1 retrotransposition is associated with genetic instability in vivo. Cell (2002) 4.79
A robust toolkit for functional profiling of the yeast genome. Mol Cell (2004) 4.69
The biochemistry of sirtuins. Annu Rev Biochem (2006) 4.32
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci U S A (2002) 4.27
DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray. Nat Genet (2003) 4.14
Mobile interspersed repeats are major structural variants in the human genome. Cell (2010) 3.60
Human L1 element target-primed reverse transcription in vitro. EMBO J (2002) 3.54
The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation. Curr Biol (2006) 3.37
Total synthesis of a functional designer eukaryotic chromosome. Science (2014) 3.31
Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription. Mol Cell (2006) 3.22
Mighty Piwis defend the germline against genome intruders. Cell (2007) 3.06
Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis. Cell (2009) 2.99
Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature (2011) 2.81
Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res (2006) 2.81
Regulated nucleosome mobility and the histone code. Nat Struct Mol Biol (2004) 2.76
A core nucleosome surface crucial for transcriptional silencing. Nat Genet (2002) 2.67
A highly active synthetic mammalian retrotransposon. Nature (2004) 2.51
Evidence that Set1, a factor required for methylation of histone H3, regulates rDNA silencing in S. cerevisiae by a Sir2-independent mechanism. Curr Biol (2002) 2.44
Toward a comprehensive temperature-sensitive mutant repository of the essential genes of Saccharomyces cerevisiae. Mol Cell (2008) 2.39
Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae. Mol Cell Biol (2005) 2.33
LINE-1 retrotransposons: modulators of quantity and quality of mammalian gene expression? Bioessays (2005) 2.24
Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases. Curr Biol (2005) 2.21
Molecular archeology of L1 insertions in the human genome. Genome Biol (2002) 2.14
Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor. Science (2010) 2.12
Acetylation of yeast AMPK controls intrinsic aging independently of caloric restriction. Cell (2011) 2.10
Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough. Cell Host Microbe (2008) 2.08
Gene function prediction from congruent synthetic lethal interactions in yeast. Mol Syst Biol (2005) 2.04
A comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation. Genes Dev (2008) 2.01
Structure of a Sir2 enzyme bound to an acetylated p53 peptide. Mol Cell (2002) 2.00
Probing nucleosome function: a highly versatile library of synthetic histone H3 and H4 mutants. Cell (2008) 1.99
Transposon-mediated genome manipulation in vertebrates. Nat Methods (2009) 1.96
Lysine succinylation and lysine malonylation in histones. Mol Cell Proteomics (2012) 1.95
Genome-wide identification of Isw2 chromatin-remodeling targets by localization of a catalytically inactive mutant. Genes Dev (2005) 1.92
GeneDesign: rapid, automated design of multikilobase synthetic genes. Genome Res (2006) 1.87
The take and give between retrotransposable elements and their hosts. Annu Rev Genet (2008) 1.86
Global synthetic-lethality analysis and yeast functional profiling. Trends Genet (2005) 1.82
Human transposon tectonics. Cell (2012) 1.81
Genome-wide consequences of deleting any single gene. Mol Cell (2013) 1.76
Short-chain fatty acid activation by acyl-coenzyme A synthetases requires SIR2 protein function in Salmonella enterica and Saccharomyces cerevisiae. Genetics (2003) 1.73
Cells satisfy the mitotic checkpoint in Taxol, and do so faster in concentrations that stabilize syntelic attachments. J Cell Biol (2009) 1.73
Transcriptional interactions between yeast tRNA genes, flanking genes and Ty elements: a genomic point of view. Genome Res (2003) 1.71
Rapid identification of monospecific monoclonal antibodies using a human proteome microarray. Mol Cell Proteomics (2012) 1.65
Polyubiquitin-sensor proteins reveal localization and linkage-type dependence of cellular ubiquitin signaling. Nat Methods (2012) 1.62
Finding friends and enemies in an enemies-only network: a graph diffusion kernel for predicting novel genetic interactions and co-complex membership from yeast genetic interactions. Genome Res (2008) 1.61
Telomeric and rDNA silencing in Saccharomyces cerevisiae are dependent on a nuclear NAD(+) salvage pathway. Genetics (2002) 1.60
Gene-breaking: a new paradigm for human retrotransposon-mediated gene evolution. Genome Res (2005) 1.58
Microarray-based genetic screen defines SAW1, a gene required for Rad1/Rad10-dependent processing of recombination intermediates. Mol Cell (2008) 1.56
A microarray-based genetic screen for yeast chronological aging factors. PLoS Genet (2010) 1.53
Efficient Tor signaling requires a functional class C Vps protein complex in Saccharomyces cerevisiae. Genetics (2007) 1.52
Active transposition in genomes. Annu Rev Genet (2012) 1.51
Active retrotransposition by a synthetic L1 element in mice. Proc Natl Acad Sci U S A (2006) 1.48
Use of mixture models in a microarray-based screening procedure for detecting differentially represented yeast mutants. Stat Appl Genet Mol Biol (2003) 1.45
Teaching synthetic biology, bioinformatics and engineering to undergraduates: the interdisciplinary Build-a-Genome course. Genetics (2008) 1.41
Structural basis for the mechanism and regulation of Sir2 enzymes. Mol Cell (2004) 1.37
Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition. Cell (2013) 1.34
Reconstitution of papillomavirus E2-mediated plasmid maintenance in Saccharomyces cerevisiae by the Brd4 bromodomain protein. Proc Natl Acad Sci U S A (2005) 1.34
TFIIIB subunit Bdp1p is required for periodic integration of the Ty1 retrotransposon and targeting of Isw2p to S. cerevisiae tDNAs. Genes Dev (2005) 1.33
Retracted Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK. Nature (2012) 1.29
dSLAM analysis of genome-wide genetic interactions in Saccharomyces cerevisiae. Methods (2007) 1.28
Retrotransposition is associated with genome instability during chronological aging. Proc Natl Acad Sci U S A (2011) 1.22
Improved microarray methods for profiling the Yeast Knockout strain collection. Nucleic Acids Res (2005) 1.21
Local definition of Ty1 target preference by long terminal repeats and clustered tRNA genes. Genome Res (2004) 1.21
5' to 3' mRNA decay factors colocalize with Ty1 gag and human APOBEC3G and promote Ty1 retrotransposition. J Virol (2010) 1.17
Inhibition of reverse transcription in vivo by elevated manganese ion concentration. Mol Cell (2002) 1.16
Histone H3 K56 hyperacetylation perturbs replisomes and causes DNA damage. Genetics (2008) 1.16
Retrotransposon Ty1 integration targets specifically positioned asymmetric nucleosomal DNA segments in tRNA hotspots. Genome Res (2012) 1.16
Transposon insertion site profiling chip (TIP-chip). Proc Natl Acad Sci U S A (2006) 1.14
Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin. J Biol Chem (2009) 1.13
A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer. Proc Natl Acad Sci U S A (2012) 1.12
SIR2 family of NAD(+)-dependent protein deacetylases. Methods Enzymol (2002) 1.09
Activation of a LTR-retrotransposon by telomere erosion. Proc Natl Acad Sci U S A (2003) 1.09
Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo. Biochem J (2004) 1.07
Nuclear expression of a group II intron is consistent with spliceosomal intron ancestry. Genes Dev (2010) 1.07
The LRS and SIN domains: two structurally equivalent but functionally distinct nucleosomal surfaces required for transcriptional silencing. Mol Cell Biol (2006) 1.06
Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochem (2011) 1.05
GeneDesign 3.0 is an updated synthetic biology toolkit. Nucleic Acids Res (2010) 1.05
HistoneHits: a database for histone mutations and their phenotypes. Genome Res (2009) 1.04
Hos2 and Set3 promote integration of Ty1 retrotransposons at tRNA genes in Saccharomyces cerevisiae. Genetics (2006) 1.03
Silent information regulator 3: the Goldilocks of the silencing complex. Genes Dev (2010) 1.03
Characterization of L1 retrotransposition with high-throughput dual-luciferase assays. Nucleic Acids Res (2010) 1.02
A nucleosomal surface defines an integration hotspot for the Saccharomyces cerevisiae Ty1 retrotransposon. Genome Res (2012) 1.01
Compensatory interactions between Sir3p and the nucleosomal LRS surface imply their direct interaction. PLoS Genet (2008) 1.01
Multichange isothermal mutagenesis: a new strategy for multiple site-directed mutations in plasmid DNA. ACS Synth Biol (2013) 1.01
Retrosequence formation restructures the yeast genome. Genes Dev (2007) 1.00
Poly(A) binding protein C1 is essential for efficient L1 retrotransposition and affects L1 RNP formation. Mol Cell Biol (2012) 0.99
Assembling DNA fragments by USER fusion. Methods Mol Biol (2012) 0.99
Identification and characterization of critical cis-acting sequences within the yeast Ty1 retrotransposon. RNA (2005) 0.98
The incredible shrinking world of DNA microarrays. Mol Biosyst (2008) 0.98
FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation. Eukaryot Cell (2004) 0.98
tRNA genes rapidly change in evolution to meet novel translational demands. Elife (2013) 0.96