Deletion of Ogg1 DNA glycosylase results in telomere base damage and length alteration in yeast.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMC 2824463)

Published in EMBO J on November 26, 2009

Authors

Jian Lu1, Yie Liu

Author Affiliations

1: Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

Articles citing this

Characterization of oxidative guanine damage and repair in mammalian telomeres. PLoS Genet (2010) 1.41

Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1. DNA Repair (Amst) (2010) 1.17

DNA repair mechanisms and the bypass of DNA damage in Saccharomyces cerevisiae. Genetics (2013) 1.17

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures. Nucleic Acids Res (2015) 0.97

Defective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects. PLoS Genet (2013) 0.97

Essential role for mammalian apurinic/apyrimidinic (AP) endonuclease Ape1/Ref-1 in telomere maintenance. Proc Natl Acad Sci U S A (2013) 0.94

Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro. Cell Cycle (2012) 0.85

Up-regulation of leucocytes genes implicated in telomere dysfunction and cellular senescence correlates with depression and anxiety severity scores. PLoS One (2012) 0.81

DNA excision repair at telomeres. DNA Repair (Amst) (2015) 0.81

Potential Risks in the Paradigm of Basic to Translational Research: A Critical Evaluation of qPCR Telomere Size Techniques. J Cancer Epidemiol Treat (2015) 0.80

Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage. Rejuvenation Res (2011) 0.80

Oxidative guanine base damage regulates human telomerase activity. Nat Struct Mol Biol (2016) 0.79

Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis. Aging Cell (2013) 0.78

Defective repair of uracil causes telomere defects in mouse hematopoietic cells. J Biol Chem (2015) 0.77

Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins. Front Genet (2016) 0.76

A new era of allele-specific diagnostics? Front Genet (2013) 0.75

Radioresistance of GGG sequences to prompt strand break formation from direct-type radiation damage. Radiat Environ Biophys (2016) 0.75

The origin of oxidized guanine resolves the puzzle of oxidation-induced telomere-length alterations. Nat Struct Mol Biol (2016) 0.75

Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers. Oncotarget (2016) 0.75

Arsenic exposure, telomere length, and expression of telomere-related genes among Bangladeshi individuals. Environ Res (2014) 0.75

Articles cited by this

Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res (1992) 34.33

Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nat Genet (2001) 13.05

Switching and signaling at the telomere. Cell (2001) 11.25

How shelterin protects mammalian telomeres. Annu Rev Genet (2008) 11.20

Reverse transcriptase motifs in the catalytic subunit of telomerase. Science (1997) 10.10

TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science (1994) 9.08

Control of telomere length by the human telomeric protein TRF1. Nature (1997) 7.62

Telomere length regulation. Annu Rev Biochem (1996) 6.98

An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell (1993) 6.89

Organization of DNA sequences and replication origins at yeast telomeres. Cell (1983) 6.43

A protein-counting mechanism for telomere length regulation in yeast. Science (1997) 4.79

Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states. Cell (2004) 4.79

Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics (1996) 4.78

Control of human telomere length by TRF1 and TRF2. Mol Cell Biol (2000) 4.54

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation. Genes Dev (1992) 4.53

Runaway telomere elongation caused by telomerase RNA gene mutations. Nature (1995) 4.34

RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability. Cell (1990) 4.25

Telomeres: beginning to understand the end. Science (1995) 4.13

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. Genes Dev (1997) 4.05

Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae. Mol Cell Biol (1999) 3.79

RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomerase. Genetics (1999) 3.55

The saccharomyces PIF1 DNA helicase inhibits telomere elongation and de novo telomere formation. Cell (1994) 3.52

Transfer of yeast telomeres to linear plasmids by recombination. Cell (1984) 3.39

A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A (2004) 3.21

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae. Genes Dev (1993) 3.18

The catalytic subunit of yeast telomerase. Proc Natl Acad Sci U S A (1997) 2.72

Tankyrase promotes telomere elongation in human cells. Curr Biol (2000) 2.67

Semi-conservative DNA replication through telomeres requires Taz1. Nature (2006) 2.53

The yeast Pif1p helicase removes telomerase from telomeric DNA. Nature (2005) 2.47

The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA. Cell (1996) 2.42

Progressive cis-inhibition of telomerase upon telomere elongation. EMBO J (1999) 2.37

Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. Nature (1996) 2.24

Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol Cell Biol (2002) 2.22

Rif1 and rif2 inhibit localization of tel1 to DNA ends. Mol Cell (2009) 2.09

Base excision repair in yeast and mammals. Mutat Res (2000) 1.99

How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex. Mol Cell (2008) 1.97

Role of oxidative stress in telomere length regulation and replicative senescence. Ann N Y Acad Sci (2000) 1.97

Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae. Mol Cell Biol (1999) 1.97

Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts. Proc Natl Acad Sci U S A (1994) 1.94

Sequence-specific DNA cleavage by Fe2+-mediated fenton reactions has possible biological implications. J Biol Chem (1999) 1.93

Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. PLoS Biol (2006) 1.89

The subtelomeric Y' repeat family in Saccharomyces cerevisiae: an experimental system for repeated sequence evolution. Genetics (1990) 1.79

The yeast Pif1p DNA helicase preferentially unwinds RNA DNA substrates. Nucleic Acids Res (2007) 1.78

Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae. J Biol Chem (2000) 1.78

Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening. FEBS Lett (1999) 1.69

Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length. Mol Cell Biol (2004) 1.66

Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. J Biol Chem (2005) 1.64

Tel1p preferentially associates with short telomeres to stimulate their elongation. Mol Cell (2007) 1.60

Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2. Nucleic Acids Res (2005) 1.59

DNA damage and repair in telomeres: relation to aging. Proc Natl Acad Sci U S A (1995) 1.56

Yeast TFIID serves as a coactivator for Rap1p by direct protein-protein interaction. Mol Cell Biol (2006) 1.31

Y'-Help1, a DNA helicase encoded by the yeast subtelomeric Y' element, is induced in survivors defective for telomerase. J Biol Chem (1998) 1.24

Oxidative damage to purines in DNA: role of mammalian Ogg1. DNA Repair (Amst) (2006) 1.23

Rap1 protein regulates telomere turnover in yeast. Proc Natl Acad Sci U S A (1998) 1.20

Telomere loops and homologous recombination-dependent telomeric circles in a Kluyveromyces lactis telomere mutant strain. Mol Cell Biol (2007) 1.20

The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity. Nucleic Acids Res (2006) 1.19

Formamidopyrimidines in DNA: mechanisms of formation, repair, and biological effects. Free Radic Biol Med (2008) 1.17

Repair of 8-oxoguanine in Saccharomyces cerevisiae: interplay of DNA repair and replication mechanisms. Free Radic Biol Med (2002) 1.15

Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase. PLoS Genet (2007) 1.12

Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants. Nucleic Acids Res (2001) 1.10

Spontaneous mutation, oxidative DNA damage, and the roles of base and nucleotide excision repair in the yeast Saccharomyces cerevisiae. Yeast (1999) 1.10

A genome-wide distribution of 8-oxoguanine correlates with the preferred regions for recombination and single nucleotide polymorphism in the human genome. Genome Res (2006) 1.06

Ty1 mobilizes subtelomeric Y' elements in telomerase-negative Saccharomyces cerevisiae survivors. Mol Cell Biol (2004) 1.05

Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells. Proc Natl Acad Sci U S A (1999) 1.03

The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. Mol Cell Biol (2009) 1.00

Site-specific oxidation at GG and GGG sequences in double-stranded DNA by benzoyl peroxide as a tumor promoter. Biochemistry (1999) 0.99

Yeast Est2p affects telomere length by influencing association of Rap1p with telomeric chromatin. Mol Cell Biol (2008) 0.82

Assessing telomeric phenotypes. Methods Mol Biol (2006) 0.81

Dynamic regulation of single-stranded telomeres in Saccharomyces cerevisiae. Genetics (2008) 0.81

Articles by these authors

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice. Proc Natl Acad Sci U S A (2004) 1.83

The dual-specificity phosphatase CDC14B bundles and stabilizes microtubules. Mol Cell Biol (2005) 1.49

Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping. Mol Cell Biol (2006) 1.45

Characterization of oxidative guanine damage and repair in mammalian telomeres. PLoS Genet (2010) 1.41

B-MYB is essential for normal cell cycle progression and chromosomal stability of embryonic stem cells. PLoS One (2008) 1.32

An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres. Proc Natl Acad Sci U S A (2005) 1.17

Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1. DNA Repair (Amst) (2010) 1.17

SLX4 assembles a telomere maintenance toolkit by bridging multiple endonucleases with telomeres. Cell Rep (2013) 1.13

Cdc14B depletion leads to centriole amplification, and its overexpression prevents unscheduled centriole duplication. J Cell Biol (2008) 1.09

PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres. Mol Biol Cell (2006) 1.07

RECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenance. J Biol Chem (2011) 1.04

Dual-tagging system for the affinity purification of mammalian protein complexes. Biotechniques (2007) 0.97

Defective repair of oxidative base lesions by the DNA glycosylase Nth1 associates with multiple telomere defects. PLoS Genet (2013) 0.97

XRCC1 haploinsufficiency in mice has little effect on aging, but adversely modifies exposure-dependent susceptibility. Nucleic Acids Res (2011) 0.94

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. PLoS One (2010) 0.92

Telomere sister chromatid exchange in telomerase deficient murine cells. Cell Cycle (2005) 0.90

FANCC suppresses short telomere-initiated telomere sister chromatid exchange. Hum Mol Genet (2009) 0.87

Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor. Proc Natl Acad Sci U S A (2011) 0.86

Nucleophosmin/B23 negatively regulates GCN5-dependent histone acetylation and transactivation. J Biol Chem (2007) 0.82

Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis. Aging Cell (2013) 0.78

Telomere, telomerase and aging. Mech Ageing Dev (2007) 0.77

The monitoring and affinity purification of proteins using dual tags with tetracysteine motifs. Methods Mol Biol (2009) 0.75

Quantitative comparison of mitotic spindles by confocal image analysis. J Biomed Opt (2005) 0.75