Published in Cancer Res on July 15, 2008
New insights of an old defense system: structure, function, and clinical relevance of the complement system. Mol Med (2010) 1.37
Application of a novel inhibitor of human CD59 for the enhancement of complement-dependent cytolysis on cancer cells. Cell Mol Immunol (2011) 0.90
Complement activation by CpG in a human whole blood loop system: mechanisms and immunomodulatory effects. J Immunol (2009) 0.81
Implication of complement system and its regulators in Alzheimer's disease. Curr Neuropharmacol (2009) 0.81
Interplay between REST and nucleolin transcription factors: a key mechanism in the overexpression of genes upon increased phosphorylation. Nucleic Acids Res (2010) 0.78
The REST gene signature predicts drug sensitivity in neuroblastoma cell lines and is significantly associated with neuroblastoma tumor stage. Int J Mol Sci (2014) 0.76
The dual role of complement in cancer and its implication in anti-tumor therapy. Ann Transl Med (2016) 0.75
Retraction: Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma. Cancer Res (2013) 0.75
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Nuclear transport and cancer: from mechanism to intervention. Nat Rev Cancer (2004) 2.85
CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59. Blood (2001) 2.53
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A novel protein that participates in nonself discrimination of malignant cells by homologous complement. Nat Med (1997) 1.61
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REST in good times and bad: roles in tumor suppressor and oncogenic activities. Cell Cycle (2006) 1.51
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CD59a is the primary regulator of membrane attack complex assembly in the mouse. J Immunol (2004) 1.45
Complement-regulatory proteins in ovarian malignancies. Int J Cancer (1997) 1.44
Transcriptional regulation: cancer, neurons and the REST. Curr Biol (2005) 1.41
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Immune evasion of tumor cells using membrane-bound complement regulatory proteins. Immunol Today (1999) 1.40
A splice variant of the neuron-restrictive silencer factor repressor is expressed in small cell lung cancer: a potential role in derepression of neuroendocrine genes and a useful clinical marker. Cancer Res (2000) 1.31
In vivo targeting of human neutralizing antibodies against CD55 and CD59 to lymphoma cells increases the antitumor activity of rituximab. Cancer Res (2007) 1.21
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Complement-mediated mechanisms in anti-GD2 monoclonal antibody therapy of murine metastatic cancer. Cancer Res (2005) 1.16
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Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the mu opioid receptor gene. J Biol Chem (2004) 1.13
Tumor-specific deposition of immunoglobulin G and complement in papillary thyroid carcinoma. Hum Pathol (1996) 1.02
The repressor element silencing transcription factor (REST)-mediated transcriptional repression requires the inhibition of Sp1. J Biol Chem (2004) 1.00
Analysis of changes in CD20, CD55, and CD59 expression on established rituximab-resistant B-lymphoma cell lines. Leuk Res (2005) 0.99
Analysis of the level of mRNA expression of the membrane regulators of complement, CD59, CD55 and CD46, in breast cancer. Int J Cancer (2004) 0.96
Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. J Immunol (2005) 0.96
CD59 expressed on a tumor cell surface modulates decay-accelerating factor expression and enhances tumor growth in a rat model of human neuroblastoma. Cancer Res (2000) 0.96
Retracted The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility. Mol Immunol (2007) 0.95
Role of zinc finger domains of the transcription factor neuron-restrictive silencer factor/repressor element-1 silencing transcription factor in DNA binding and nuclear localization. J Biol Chem (2001) 0.94
Small molecules in an RNAi world. Mol Biosyst (2005) 0.93
Recruitment of heterogeneous nuclear ribonucleoprotein A1 in vivo to the LMP/TAP region of the major histocompatibility complex. J Biol Chem (2002) 0.92
Retracted p53 regulates cellular resistance to complement lysis through enhanced expression of CD59. Cancer Res (2006) 0.92
Antibody-based immunotherapy in high-risk neuroblastoma. Expert Rev Mol Med (2007) 0.90
Glycation of CD59 impairs complement regulation on erythrocytes from diabetic subjects. Immunology (2005) 0.87
Satellite DNA binding and cellular localisation of RNA helicase P68. J Cell Sci (2005) 0.87
Genomic structure and chromosomal localization of GML (GPI-anchored molecule-like protein), a gene induced by p53. Genomics (1997) 0.85
Survival of children with neuroblastoma. time trends and regional differences in Europe, 1978--1992. Eur J Cancer (2001) 0.84
Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement. Cancer Res (2007) 0.83
Tumour-specific arginine vasopressin promoter activation in small-cell lung cancer. Br J Cancer (1999) 0.81
Immunohistochemistry of complement response on human renal cell carcinoma biopsies. Tumori (1997) 0.80
Inhibition of p53 activity in vitro and in living cells by a synthetic peptide derived from its core domain. Cell Cycle (2003) 0.80
The complement inhibitor CD59 and the lymphocyte function-associated antigen-3 (LFA-3, CD58) genes possess functional binding sites for the p53 tumor suppressor protein. Anticancer Res (2003) 0.78
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature (2006) 24.29
A high-resolution atlas of nucleosome occupancy in yeast. Nat Genet (2007) 12.21
The DNA-encoded nucleosome organization of a eukaryotic genome. Nature (2008) 11.41
Diversity and complexity in DNA recognition by transcription factors. Science (2009) 9.07
Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell (2007) 8.43
FunSpec: a web-based cluster interpreter for yeast. BMC Bioinformatics (2002) 8.01
Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell (2008) 7.93
Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform. Mol Cell (2004) 7.32
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell (2005) 7.21
Most "dark matter" transcripts are associated with known genes. PLoS Biol (2010) 6.60
Mapping pathways and phenotypes by systematic gene overexpression. Mol Cell (2006) 6.42
Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling. Cell (2006) 5.72
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways. Nat Biotechnol (2003) 5.60
A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell (2003) 5.57
Exploration of essential gene functions via titratable promoter alleles. Cell (2004) 5.21
DNA-binding specificities of human transcription factors. Cell (2013) 5.14
Probing microRNAs with microarrays: tissue specificity and functional inference. RNA (2004) 4.91
A compendium of RNA-binding motifs for decoding gene regulation. Nature (2013) 4.91
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J (2010) 4.78
A critical assessment of Mus musculus gene function prediction using integrated genomic evidence. Genome Biol (2008) 4.78
Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters. Nat Genet (2002) 4.68
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Mol Cell (2007) 4.58
A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Mol Cell (2008) 4.49
High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell (2004) 4.18
Exploring the mode-of-action of bioactive compounds by chemical-genetic profiling in yeast. Cell (2006) 4.03
Rapid tRNA decay can result from lack of nonessential modifications. Mol Cell (2006) 3.86
Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome. Proc Natl Acad Sci U S A (2006) 3.80
Genome-wide analysis of mRNA stability using transcription inhibitors and microarrays reveals posttranscriptional control of ribosome biogenesis factors. Mol Cell Biol (2004) 3.72
Identification of a bacterial type III effector family with G protein mimicry functions. Cell (2006) 3.47
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. Genome Res (2010) 3.46
Rapid and systematic analysis of the RNA recognition specificities of RNA-binding proteins. Nat Biotechnol (2009) 3.44
Using expression profiling data to identify human microRNA targets. Nat Methods (2007) 3.37
A panoramic view of yeast noncoding RNA processing. Cell (2003) 3.11
The synthetic genetic interaction spectrum of essential genes. Nat Genet (2005) 3.06
G+C content dominates intrinsic nucleosome occupancy. BMC Bioinformatics (2009) 3.05
IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis. Brain (2008) 2.91
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell (2011) 2.89
Conservation of core gene expression in vertebrate tissues. J Biol (2009) 2.84
Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. Proc Natl Acad Sci U S A (2004) 2.80
Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome. PLoS Biol (2008) 2.73
Why are there still over 1000 uncharacterized yeast genes? Genetics (2007) 2.71
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses. Immunity (2013) 2.69
C-reactive protein-induced in vitro endothelial cell activation is an artefact caused by azide and lipopolysaccharide. Arterioscler Thromb Vasc Biol (2005) 2.64
SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. Dev Cell (2007) 2.64
High nucleosome occupancy is encoded at human regulatory sequences. PLoS One (2010) 2.43
RBPDB: a database of RNA-binding specificities. Nucleic Acids Res (2010) 2.42
RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell (2003) 2.40
Identifying transcription factor functions and targets by phenotypic activation. Proc Natl Acad Sci U S A (2006) 2.39
Evaluation of methods for modeling transcription factor sequence specificity. Nat Biotechnol (2013) 2.34
BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Curr Biol (2005) 2.32
H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex. Mol Cell (2007) 2.32
Alternative splicing of conserved exons is frequently species-specific in human and mouse. Trends Genet (2005) 2.26
Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. J Clin Invest (2010) 2.18
Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Nat Genet (2005) 2.15
Conserved structure for single-stranded telomeric DNA recognition. Science (2002) 2.11
TFCat: the curated catalog of mouse and human transcription factors. Genome Biol (2009) 2.06
The draft genome and transcriptome of Cannabis sativa. Genome Biol (2011) 2.03
Conserved expression without conserved regulatory sequence: the more things change, the more they stay the same. Trends Genet (2010) 1.97
Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol (2008) 1.92
Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts. Blood (2002) 1.87
RankMotif++: a motif-search algorithm that accounts for relative ranks of K-mers in binding transcription factors. Bioinformatics (2007) 1.86
H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Mol Cell Biol (2005) 1.82
Functional coordination of alternative splicing in the mammalian central nervous system. Genome Biol (2007) 1.80
RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins. PLoS Comput Biol (2010) 1.78
C3-dependent mechanism of microglial priming relevant to multiple sclerosis. Proc Natl Acad Sci U S A (2012) 1.73
Nucleosome sequence preferences influence in vivo nucleosome organization. Nat Struct Mol Biol (2010) 1.72
The splicing factor Prp43p, a DEAH box ATPase, functions in ribosome biogenesis. Mol Cell Biol (2006) 1.70
Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis. Arch Neurol (2012) 1.67
Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. Elife (2013) 1.64
Dimerization of complement factor H-related proteins modulates complement activation in vivo. Proc Natl Acad Sci U S A (2013) 1.63
Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk. J Immunol (2003) 1.61
Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk. Proc Natl Acad Sci U S A (2011) 1.60
Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell (2007) 1.56
CD59a deficiency exacerbates accelerated nephrotoxic nephritis in mice. J Am Soc Nephrol (2003) 1.54
Transcriptional networks: reverse-engineering gene regulation on a global scale. Curr Opin Microbiol (2004) 1.54
Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice. Blood (2008) 1.53
The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity. Hum Mol Genet (2009) 1.52
Tetracycline protects against dermonecrosis induced by Loxosceles spider venom. J Invest Dermatol (2007) 1.50
Alternative roles for CD59. Mol Immunol (2006) 1.47
A systematic search for new mammalian noncoding RNAs indicates little conserved intergenic transcription. BMC Genomics (2005) 1.47
RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits. Mol Cell Biol (2004) 1.46
CD59a is the primary regulator of membrane attack complex assembly in the mouse. J Immunol (2004) 1.45
A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer. Blood (2012) 1.45
The human complement fragment receptor, C5L2, is a recycling decoy receptor. Mol Immunol (2008) 1.45
The specificities of four yeast dihydrouridine synthases for cytoplasmic tRNAs. J Biol Chem (2004) 1.43
Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. Eur J Immunol (2003) 1.40
Letter in response to Bisoendial et al: "activation of inflammation and coagulation after infusion of C-reactive protein in humans". Circ Res (2005) 1.39
Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B. Proc Natl Acad Sci U S A (2009) 1.36
Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina. J Biol Chem (2010) 1.36
Molecular dissection of interactions between components of the alternative pathway of complement and decay accelerating factor (CD55). J Biol Chem (2004) 1.35
The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. J Cell Sci (2013) 1.33
Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration. Invest Ophthalmol Vis Sci (2008) 1.32
Analysis of Escherichia coli RNase E and RNase III activity in vivo using tiling microarrays. Nucleic Acids Res (2010) 1.32
Establishing legitimacy and function in the new transcriptome. Brief Funct Genomic Proteomic (2009) 1.31
CD59, a complement regulatory protein, controls choroidal neovascularization in a mouse model of wet-type age-related macular degeneration. J Immunol (2007) 1.31
Holding T cells in check--a new role for complement regulators? Trends Immunol (2006) 1.30
Glucocorticoids induce protein S-dependent phagocytosis of apoptotic neutrophils by human macrophages. J Immunol (2009) 1.30