Published in FASEB J on November 19, 2004
Erythropoietin deficiency decreases vascular stability in mice. J Clin Invest (2008) 2.45
Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia. J Physiol (2007) 1.56
Erythropoietin sustains cognitive function and brain volume after neonatal stroke. Dev Neurosci (2009) 1.26
Erythropoietin: a multimodal neuroprotective agent. Exp Transl Stroke Med (2009) 1.14
Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse. Exp Eye Res (2009) 1.04
Erythropoietin in the intensive care unit: beyond treatment of anemia. Ann Intensive Care (2011) 1.03
Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies. J Physiol (2005) 1.00
Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells. Mol Vis (2011) 0.98
Involvement of erythropoietin in retinal ischemic preconditioning. Anesthesiology (2009) 0.97
Up-regulated endogenous erythropoietin/erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension. Cell Mol Neurobiol (2007) 0.95
Evidence That Erythropoietin Modulates Neuroinflammation through Differential Action on Neurons, Astrocytes, and Microglia. Front Immunol (2014) 0.92
Enhanced survival of melanopsin-expressing retinal ganglion cells after injury is associated with the PI3 K/Akt pathway. Cell Mol Neurobiol (2008) 0.87
Erythropoietin neuroprotection with traumatic brain injury. Pathophysiology (2012) 0.85
Tissue inhibitor of matrix metalloproteinase-1 mediates erythropoietin-induced neuroprotection in hypoxia ischemia. Neurobiol Dis (2011) 0.83
Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush. PLoS One (2014) 0.82
Safety and angiogenic effects of systemic gene delivery of a modified erythropoietin. Gene Ther (2015) 0.82
Erythropoietin protects adult retinal ganglion cells against NMDA-, trophic factor withdrawal-, and TNF-α-induced damage. PLoS One (2013) 0.82
Differential modulation of angiogenesis by erythropoiesis-stimulating agents in a mouse model of ischaemic retinopathy. PLoS One (2010) 0.82
Erythropoietin and polyneuropathy in older persons. Mech Ageing Dev (2008) 0.82
Aqueous humor and serum erythropoietin levels in patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma. Int Ophthalmol (2010) 0.82
[Erythropoietin protects retinal ganglion cells and visual function after ocular ischemia and optic nerve compression]. Ophthalmologe (2010) 0.81
Erythropoietin: when liability becomes asset in neurovascular repair. J Clin Invest (2008) 0.80
Erythropoetin receptor expression in the human diabetic retina. BMC Res Notes (2009) 0.80
Safety and efficacy of intravitreal injection of recombinant erythropoietin for protection of photoreceptor cells in a rat model of retinal detachment. Eye (Lond) (2011) 0.79
Revisiting the role of erythropoietin for treatment of ocular disorders. Eye (Lond) (2016) 0.77
Erythropoietin in ophthalmology: A literature review. J Curr Ophthalmol (2016) 0.77
Erythropoietin in stroke therapy: friend or foe. Curr Med Chem (2015) 0.76
Stroke in the eye of the beholder. Med Hypotheses (2013) 0.76
Hypoxia-Inducible Factor-1α Target Genes Contribute to Retinal Neuroprotection. Front Cell Neurosci (2017) 0.75
A Coral-Derived Compound Improves Functional Recovery after Spinal Cord Injury through Its Antiapoptotic and Anti-Inflammatory Effects. Mar Drugs (2016) 0.75
Erythropoietin either Prevents or Exacerbates Retinal Damage from Eye Trauma Depending on Treatment Timing. Optom Vis Sci (2016) 0.75
Upregulation of neurotrophic factor-related gene expression in retina with experimental autoimmune uveoretinitis by intravitreal injection of tacrolimus (FK506). Br J Ophthalmol (2007) 0.75
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat Med (2011) 3.31
HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration. Nat Med (2002) 2.69
The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function. Exp Physiol (2012) 2.20
Air quality, stroke, and coronary events: results of the Heinz Nixdorf Recall Study from the Ruhr Region. Dtsch Arztebl Int (2015) 2.10
Moderate altitude but not additional endurance training increases markers of oxidative stress in exhaled breath condensate. Eur J Appl Physiol (2009) 1.99
Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain (2009) 1.89
Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circ Res (2004) 1.88
Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis. Immunity (2002) 1.87
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Mol Cell Biol (2003) 1.75
Erythropoietin enhances immune responses in mice. Eur J Immunol (2007) 1.68
VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain (2004) 1.67
The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J (2006) 1.64
Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia. J Physiol (2007) 1.56
Functional NMDA receptors in rat erythrocytes. Am J Physiol Cell Physiol (2010) 1.54
Regulating cellular oxygen sensing by hydroxylation. Cardiovasc Res (2006) 1.54
Differential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5. EMBO J (2003) 1.53
TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration. Neurobiol Dis (2008) 1.52
Erythropoietic and non-erythropoietic functions of erythropoietin in mouse models. J Physiol (2011) 1.46
Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1. Neurobiol Dis (2005) 1.45
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J (2005) 1.40
Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice. Proc Natl Acad Sci U S A (2009) 1.37
Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. FASEB J (2003) 1.36
Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression. FASEB J (2002) 1.36
Neural stem/precursor cells for the treatment of ischemic stroke. J Neurol Sci (2007) 1.31
Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways. J Neurosci (2006) 1.31
Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain (2011) 1.29
Constitutive overexpression of human erythropoietin protects the mouse retina against induced but not inherited retinal degeneration. J Neurosci (2004) 1.27
Differentiating embryonic stem cells into embryoid bodies. Methods Mol Biol (2004) 1.26
HIFs and tumors--causes and consequences. Am J Physiol Regul Integr Comp Physiol (2004) 1.23
Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity. Blood (2003) 1.22
Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism. Circ Res (2011) 1.22
Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor. Cancer Res (2002) 1.20
Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors. FASEB J (2002) 1.20
Animal models of ischemic stroke. Part two: modeling cerebral ischemia. Open Neurol J (2010) 1.18
Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis. Arthritis Rheum (2004) 1.17
Sensing and responding to hypoxia via HIF in model invertebrates. J Insect Physiol (2006) 1.17
Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain. Neuroimage (2007) 1.14
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. Acta Neuropathol (2013) 1.13
Rescue of lethal c-KitW/W mice by erythropoietin. Blood (2004) 1.12
Excessive erythrocytosis compromises the blood-endothelium interface in erythropoietin-overexpressing mice. J Physiol (2011) 1.11
Central necrosis in isolated hypoxic human pancreatic islets: evidence for postisolation ischemia. Cell Transplant (2005) 1.11
Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia. Nat Neurosci (2006) 1.10
S-glutathionylation of the Na,K-ATPase catalytic α subunit is a determinant of the enzyme redox sensitivity. J Biol Chem (2012) 1.09
Macrophages as novel target cells for erythropoietin. Haematologica (2010) 1.08
Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult. J Cereb Blood Flow Metab (2010) 1.08
Erythropoietin treatment leads to reduced blood glucose levels and body mass: insights from murine models. J Endocrinol (2010) 1.07
Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions. Eur J Appl Physiol (2005) 1.07
Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction. Mol Cell Neurosci (2002) 1.06
Non-erythroid activities of erythropoietin: Functional effects on murine dendritic cells. Mol Immunol (2008) 1.06
Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res (2005) 1.06
Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab (2010) 1.06
When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. Exp Biol Med (Maywood) (2005) 1.06
NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biol Chem (2005) 1.06
Enhanced erythro-phagocytosis in polycythemic mice overexpressing erythropoietin. Blood (2007) 1.05
Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species. J Cell Sci (2006) 1.05
Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice. FASEB J (2002) 1.05
Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pineal Res (2008) 1.05
Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice. Ann Neurol (2002) 1.04
Non-erythroid functions of erythropoietin. Adv Exp Med Biol (2003) 1.04
Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta Neuropathol (2011) 1.04
Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice. Stroke (2003) 1.04
Nociceptive tuning by stem cell factor/c-Kit signaling. Neuron (2007) 1.03
Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression. Mol Cancer Res (2008) 1.03
Hypoxic up-regulation of erythroid 5-aminolevulinate synthase. Blood (2002) 1.02
Brain-derived neurotrophic factor, stress and depression: a minireview. Brain Res Bull (2008) 1.02
Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation. Stem Cells (2012) 1.02
Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence. J Nucl Med (2004) 1.02
Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond) (2013) 1.02
Erythrocytosis: the HIF pathway in control. Blood (2013) 1.01
Histamine H1 receptor promotes atherosclerotic lesion formation by increasing vascular permeability for low-density lipoproteins. Arterioscler Thromb Vasc Biol (2010) 1.01
Physiologically low oxygen concentrations in fetal skin regulate hypoxia-inducible factor 1 and transforming growth factor-beta3. FASEB J (2002) 1.00
Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies. J Physiol (2005) 1.00
HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius. Respir Physiol Neurobiol (2004) 0.99
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis. Brain (2012) 0.99
Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration. Am J Physiol Regul Integr Comp Physiol (2006) 0.98
Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain. Sci Signal (2010) 0.98
Hypoxia selectively disrupts brain microvascular endothelial tight junction complexes through a hypoxia-inducible factor-1 (HIF-1) dependent mechanism. J Cell Physiol (2014) 0.98
Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells. Biochem Biophys Res Commun (2002) 0.98
Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN. Mol Cell Biol (2003) 0.97
Hypoxia: adapting to high altitude by mutating EPAS-1, the gene encoding HIF-2α. High Alt Med Biol (2011) 0.96
Sleep EEG changes after middle cerebral artery infarcts in mice: different effects of striatal and cortical lesions. Sleep (2006) 0.96
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood (2012) 0.95