Published in Neurobiol Dis on March 28, 2008
Regulation of innate immune responses in the brain. Nat Rev Immunol (2009) 3.41
Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. Lancet Neurol (2009) 2.98
Toll-like receptors in neurodegeneration. Brain Res Rev (2008) 2.15
Toll-like receptor signaling in neural plasticity and disease. Trends Neurosci (2011) 2.01
Linking oxidative stress to inflammation: Toll-like receptors. Free Radic Biol Med (2010) 1.85
Microglial activation in stroke: therapeutic targets. Neurotherapeutics (2010) 1.84
Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clin Sci (Lond) (2011) 1.73
An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol (2010) 1.64
HMBG1 mediates ischemia-reperfusion injury by TRIF-adaptor independent Toll-like receptor 4 signaling. J Cereb Blood Flow Metab (2010) 1.39
Microglia during development and aging. Pharmacol Ther (2013) 1.30
Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity. Int J Environ Res Public Health (2011) 1.27
Genomic biomarkers and cellular pathways of ischemic stroke by RNA gene expression profiling. Neurology (2010) 1.23
Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS? Br J Pharmacol (2010) 1.12
Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB, JAK-STAT and JNK stress kinase pathways. J Inflamm (Lond) (2011) 1.11
CNS immune responses following experimental stroke. Neurocrit Care (2009) 1.11
Toll-like receptor 4 contributes to retinal ischemia/reperfusion injury. Mol Vis (2010) 1.09
Toll-like receptors in cerebral ischemic inflammatory injury. J Neuroinflammation (2011) 1.06
The high-mobility group box-1 nuclear factor mediates retinal injury after ischemia reperfusion. Invest Ophthalmol Vis Sci (2011) 1.05
Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia. Proc Natl Acad Sci U S A (2009) 1.04
Targeting neutrophils in ischemic stroke: translational insights from experimental studies. J Cereb Blood Flow Metab (2015) 1.03
Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke. J Cereb Blood Flow Metab (2010) 1.03
Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling. Invest Ophthalmol Vis Sci (2010) 1.01
Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway. EMBO Mol Med (2010) 1.00
A clear and present danger: endogenous ligands of Toll-like receptors. Neuromolecular Med (2009) 0.99
Innate inflammatory responses in stroke: mechanisms and potential therapeutic targets. Curr Med Chem (2014) 0.99
Novel role for the innate immune receptor Toll-like receptor 4 (TLR4) in the regulation of the Wnt signaling pathway and photoreceptor apoptosis. PLoS One (2012) 0.98
Innate immune regulation by toll-like receptors in the brain. ISRN Neurol (2012) 0.97
Activin A is essential for neurogenesis following neurodegeneration. Stem Cells (2009) 0.96
Exercise Therapy Downregulates the Overexpression of TLR4, TLR2, MyD88 and NF-κB after Cerebral Ischemia in Rats. Int J Mol Sci (2013) 0.94
Protection of hippocampal neurogenesis from toll-like receptor 4-dependent innate immune activation by ablation of prostaglandin E2 receptor subtype EP1 or EP2. Am J Pathol (2009) 0.94
Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles. Prog Neurobiol (2014) 0.94
Immune regulation toward immunomodulation for neuroprotection in glaucoma. Curr Opin Pharmacol (2012) 0.93
Toll-like 4 receptor inhibitor TAK-242 decreases neuroinflammation in rat brain frontal cortex after stress. J Neuroinflammation (2014) 0.93
The innate immune system in Alzheimer's disease. Int J Cell Biol (2013) 0.92
Mechanisms and potential therapeutic applications of microglial activation after brain injury. CNS Neurosci Ther (2014) 0.89
Toll-like receptors in ischaemia and its potential role in the pathophysiology of muscle damage in critical limb ischaemia. Cardiol Res Pract (2012) 0.89
TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice. J Cereb Blood Flow Metab (2015) 0.88
Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism. Mol Immunol (2012) 0.86
A novel protective role for the innate immunity Toll-Like Receptor 3 (TLR3) in the retina via Stat3. Mol Cell Neurosci (2014) 0.85
Different TLR4 expression and microglia/macrophage activation induced by hemorrhage in the rat spinal cord after compressive injury. J Neuroinflammation (2013) 0.84
Lipopolysaccharide from Rhodobacter sphaeroides Attenuates Microglia-Mediated Inflammation and Phagocytosis and Directs Regulatory T Cell Response. Int J Inflam (2015) 0.83
Early Blockade of TLRs MyD88-Dependent Pathway May Reduce Secondary Spinal Cord Injury in the Rats. Evid Based Complement Alternat Med (2012) 0.82
Activation of BV2 microglia by lipopolysaccharide triggers an inflammatory reaction in PC12 cell apoptosis through a toll-like receptor 4-dependent pathway. Cell Stress Chaperones (2014) 0.81
Possible involvement of TLRs and hemichannels in stress-induced CNS dysfunction via mastocytes, and glia activation. Mediators Inflamm (2013) 0.81
Glial and Neuroimmune Mechanisms as Critical Modulators of Drug Use and Abuse. Neuropsychopharmacology (2016) 0.81
Astrocytic Toll-like receptor 3 is associated with ischemic preconditioning-induced protection against brain ischemia in rodents. PLoS One (2014) 0.80
Reduced photoreceptor death and improved retinal function during retinal degeneration in mice lacking innate immunity adaptor protein MyD88. Exp Neurol (2015) 0.78
Method parameters' impact on mortality and variability in mouse stroke experiments: a meta-analysis. Sci Rep (2016) 0.77
CD40 Negatively Regulates ATP-TLR4-Activated Inflammasome in Microglia. Cell Mol Neurobiol (2016) 0.77
Combination treatment with low-dose Niaspan and tissue plasminogen activator provides neuroprotection after embolic stroke in rats. J Neurol Sci (2011) 0.77
Function and mechanism of toll-like receptors in cerebral ischemic tolerance: from preconditioning to treatment. J Neuroinflammation (2015) 0.77
Cinnamaldehyde inhibits inflammation and brain damage in a mouse model of permanent cerebral ischaemia. Br J Pharmacol (2015) 0.77
Stroke in the eye of the beholder. Med Hypotheses (2013) 0.76
Cellular Stress Response and Immune Signaling in Retinal Ischemia-Reperfusion Injury. Front Immunol (2016) 0.75
Future Perspectives for Brain Pharmacotherapies: Implications of Drug Transport Processes at the Blood-brain Barrier. Ther Adv Neurol Disord (2008) 0.75
Lack of the scavenger receptor CD36 alters microglial phenotypes after neonatal stroke. J Neurochem (2015) 0.75
Isoquercetin activates the ERK1/2-Nrf2 pathway and protects against cerebral ischemia-reperfusion injury in vivo and in vitro. Exp Ther Med (2017) 0.75
Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors. Prog Neuropsychopharmacol Biol Psychiatry (2016) 0.75
Regulation of microglial activation in stroke. Acta Pharmacol Sin (2017) 0.75
Minocycline-Suppression of Early Peripheral Inflammation Reduces Hypoxia-Induced Neonatal Brain Injury. Front Neurosci (2017) 0.75
Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis. Science (2004) 2.38
Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. J Clin Invest (2011) 2.37
Air quality, stroke, and coronary events: results of the Heinz Nixdorf Recall Study from the Ruhr Region. Dtsch Arztebl Int (2015) 2.10
Sleep-disordered breathing and periodic limb movements in narcolepsy with cataplexy: a systematic analysis of 35 consecutive patients. Eur Neurol (2013) 2.05
Violence in sleep. Brain (2010) 1.92
Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain (2009) 1.89
From abstract to impact in cardiovascular research: factors predicting publication and citation. Eur Heart J (2012) 1.79
Validation of the fatigue severity scale in a Swiss cohort. Sleep (2008) 1.72
Sleep-wake disturbances 3 years after traumatic brain injury. J Neurol Neurosurg Psychiatry (2010) 1.71
VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena. Brain (2004) 1.67
The phosphatidylinositol-3 kinase/Akt pathway mediates VEGF's neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia. FASEB J (2006) 1.64
Sleep-wake disturbances 6 months after traumatic brain injury: a prospective study. Brain (2007) 1.64
Loss of hypocretin (orexin) neurons with traumatic brain injury. Ann Neurol (2009) 1.54
Sleep homeostasis in the rat is preserved during chronic sleep restriction. Proc Natl Acad Sci U S A (2010) 1.49
Effects of sleep fragmentation on the arousability to resistive loading in NREM and REM sleep in normal men. Sleep (2006) 1.48
Protective roles of SIRT1 in atherosclerosis. Cell Cycle (2011) 1.47
Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1. Neurobiol Dis (2005) 1.45
Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. FASEB J (2005) 1.40
SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis. Eur Heart J (2010) 1.40
Sleep-related breathing and sleep-wake disturbances in ischemic stroke. Neurology (2009) 1.39
Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. Circulation (2007) 1.39
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice. Aging (Albany NY) (2010) 1.32
Neural stem/precursor cells for the treatment of ischemic stroke. J Neurol Sci (2007) 1.31
Human vascular endothelial growth factor protects axotomized retinal ganglion cells in vivo by activating ERK-1/2 and Akt pathways. J Neurosci (2006) 1.31
Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity. Eur Heart J (2013) 1.31
Post-acute delivery of erythropoietin induces stroke recovery by promoting perilesional tissue remodelling and contralesional pyramidal tract plasticity. Brain (2011) 1.29
Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J (2004) 1.25
Abnormal activity in hypothalamus and amygdala during humour processing in human narcolepsy with cataplexy. Brain (2007) 1.24
The clinical spectrum of narcolepsy with cataplexy: a reappraisal. J Sleep Res (2004) 1.24
Animal models of ischemic stroke. Part two: modeling cerebral ischemia. Open Neurol J (2010) 1.18
Dissociation of periodic leg movements from arousals in restless legs syndrome. Ann Neurol (2012) 1.14
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation. Acta Neuropathol (2013) 1.13
Hyperactive S6K1 mediates oxidative stress and endothelial dysfunction in aging: inhibition by resveratrol. PLoS One (2011) 1.12
Morphological differences in Parkinson's disease with and without rest tremor. J Neurol (2009) 1.12
Reduced connexin43 expression limits neointima formation after balloon distension injury in hypercholesterolemic mice. Circulation (2006) 1.11
Inhibition of multidrug resistance transporter-1 facilitates neuroprotective therapies after focal cerebral ischemia. Nat Neurosci (2006) 1.10
Endothelial dysfunction and arterial stiffness in ischemic stroke: the role of sleep-disordered breathing. Stroke (2013) 1.08
c-Jun N-terminal kinase 2 deficiency protects against hypercholesterolemia-induced endothelial dysfunction and oxidative stress. Circulation (2008) 1.08
Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells. Cardiovasc Res (2010) 1.07
Statins (HMG-CoA reductase inhibitors) reduce CD40 expression in human vascular cells. Cardiovasc Res (2003) 1.07
Abnormal activity in reward brain circuits in human narcolepsy with cataplexy. Ann Neurol (2010) 1.07
Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? Brain (2010) 1.07
Inhibition of neuronal apoptosis in vitro and in vivo using TAT-mediated protein transduction. Mol Cell Neurosci (2002) 1.06
Role of Nogo-A in neuronal survival in the reperfused ischemic brain. J Cereb Blood Flow Metab (2010) 1.06
Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets. Atherosclerosis (2009) 1.06
Evolution of neurological, neuropsychological and sleep-wake disturbances after paramedian thalamic stroke. Stroke (2007) 1.06
Hypocretins (orexins) and sleep-wake disorders. Lancet Neurol (2005) 1.06
Signal transduction pathways involved in melatonin-induced neuroprotection after focal cerebral ischemia in mice. J Pineal Res (2005) 1.06
When melatonin gets on your nerves: its beneficial actions in experimental models of stroke. Exp Biol Med (Maywood) (2005) 1.06
PARP1 is required for adhesion molecule expression in atherogenesis. Cardiovasc Res (2007) 1.06
Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy. Circ Res (2009) 1.06
Heart-infiltrating prominin-1+/CD133+ progenitor cells represent the cellular source of transforming growth factor beta-mediated cardiac fibrosis in experimental autoimmune myocarditis. Circ Res (2009) 1.06
Delayed melatonin administration promotes neuronal survival, neurogenesis and motor recovery, and attenuates hyperactivity and anxiety after mild focal cerebral ischemia in mice. J Pineal Res (2008) 1.05
Intravenous TAT-Bcl-Xl is protective after middle cerebral artery occlusion in mice. Ann Neurol (2002) 1.04
RANTES (regulated on activation, normal T cell expressed and secreted), inflammation, obesity, and the metabolic syndrome. Circulation (2007) 1.04
Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain. Acta Neuropathol (2011) 1.04
Intravenous TAT-GDNF is protective after focal cerebral ischemia in mice. Stroke (2003) 1.04
Brain-derived neurotrophic factor, stress and depression: a minireview. Brain Res Bull (2008) 1.02
Polypharmacy is associated with an increased risk of bleeding in elderly patients with venous thromboembolism. J Gen Intern Med (2014) 1.02
Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation. Stem Cells (2012) 1.02
Total dream loss: a distinct neuropsychological dysfunction after bilateral PCA stroke. Ann Neurol (2004) 1.02
Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence. J Nucl Med (2004) 1.02
Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond) (2013) 1.02
Multiple sleep latency measures in narcolepsy and behaviourally induced insufficient sleep syndrome. Sleep Med (2009) 1.01
Discontinuation of nonsteroidal anti-inflammatory drug therapy and risk of acute myocardial infarction. Arch Intern Med (2004) 1.00
Dimethyl sulfoxide inhibits tissue factor expression, thrombus formation, and vascular smooth muscle cell activation: a potential treatment strategy for drug-eluting stents. Circulation (2006) 0.99
Deletion of the activated protein-1 transcription factor JunD induces oxidative stress and accelerates age-related endothelial dysfunction. Circulation (2013) 0.99
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis. Brain (2012) 0.99
Current use of nonsteroidal antiinflammatory drugs and the risk of acute myocardial infarction. Pharmacotherapy (2005) 0.99
Longitudinal polysomnographic assessment from acute to subacute phase in infratentorial versus supratentorial stroke. Cerebrovasc Dis (2014) 0.98
Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain. Sci Signal (2010) 0.98
Letter by Winnik et Al regarding article, "conversion of cardiovascular conference abstracts to publications". Circulation (2013) 0.98
Standard procedures for adults in accredited sleep medicine centres in Europe. J Sleep Res (2011) 0.97
Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata. Eur Heart J (2011) 0.97
Evidence for metabolic hypothalamo-amygdala dysfunction in narcolepsy. Sleep (2009) 0.97
Pseudocataplexy in narcolepsy with cataplexy. Sleep Med (2010) 0.96