Published in J Immunol on December 01, 2004
Osteoimmunology: interactions of the bone and immune system. Endocr Rev (2008) 2.32
B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood (2007) 2.16
Ebf1-dependent control of the osteoblast and adipocyte lineages. Bone (2008) 1.23
The role of gap junctions in megakaryocyte-mediated osteoblast proliferation and differentiation. Bone (2008) 1.21
Role of Bcl2 in osteoclastogenesis and PTH anabolic actions in bone. J Bone Miner Res (2008) 1.05
Immature and mature megakaryocytes enhance osteoblast proliferation and inhibit osteoclast formation. J Cell Biochem (2010) 1.01
Regulation of bone by the adaptive immune system in arthritis. Arthritis Res Ther (2011) 1.00
Osteoblast-specific overexpression of human interleukin-7 rescues the bone mass phenotype of interleukin-7-deficient female mice. J Bone Miner Res (2012) 0.95
How B cells influence bone biology in health and disease. Bone (2010) 0.94
Bone structure and B-cell populations, crippled by obesity, are partially rescued by brief daily exposure to low-magnitude mechanical signals. FASEB J (2012) 0.89
Examination of ERα signaling pathways in bone of mutant mouse models reveals the importance of ERE-dependent signaling. Endocrinology (2012) 0.87
Cell biology of osteoimmunology. Wien Med Wochenschr (2010) 0.82
The paired-box homeodomain transcription factor Pax6 binds to the upstream region of the TRAP gene promoter and suppresses receptor activator of NF-κB ligand (RANKL)-induced osteoclast differentiation. J Biol Chem (2013) 0.79
Influence of Rituximab on markers of bone remodeling in patients with rheumatoid arthritis: a prospective open-label pilot study. Rheumatol Int (2010) 0.77
DMSO regulates osteoclast development in vitro. In Vitro Cell Dev Biol Anim (2011) 0.77
Cx43 expressed on bone marrow stromal cells plays an essential role in multiple myeloma cell survival and drug resistance. Arch Med Sci (2016) 0.77
Lnk Deficiency Leads to TPO-Mediated Osteoclastogenesis and Increased Bone Mass Phenotype. J Cell Biochem (2017) 0.75
Two levels of protection for the B cell genome during somatic hypermutation. Nature (2008) 5.32
The in vivo pattern of binding of RAG1 and RAG2 to antigen receptor loci. Cell (2010) 3.88
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc Natl Acad Sci U S A (2003) 3.46
A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature (2011) 2.58
Targeting of somatic hypermutation. Nat Rev Immunol (2006) 2.42
Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. J Exp Med (2005) 2.21
Serum sclerostin levels negatively correlate with parathyroid hormone levels and free estrogen index in postmenopausal women. J Clin Endocrinol Metab (2010) 2.05
Identification of an AID-independent pathway for chromosomal translocations between the Igh switch region and Myc. Nat Immunol (2004) 2.00
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol (2009) 1.98
Defective DNA repair and increased genomic instability in Artemis-deficient murine cells. J Exp Med (2003) 1.98
Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation. J Exp Med (2009) 1.89
Balancing AID and DNA repair during somatic hypermutation. Trends Immunol (2009) 1.86
Identification of multiple osteoclast precursor populations in murine bone marrow. J Bone Miner Res (2005) 1.75
Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis. Proc Natl Acad Sci U S A (2010) 1.73
Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity. Cell (2002) 1.73
Pax5 is required for recombination of transcribed, acetylated, 5' IgH V gene segments. Genes Dev (2003) 1.69
Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein. Mol Cancer Ther (2005) 1.59
Distinct requirements of microRNAs in NK cell activation, survival, and function. J Immunol (2010) 1.48
Engraftment of a vascularized human skin equivalent. FASEB J (2003) 1.43
The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells. Proc Natl Acad Sci U S A (2006) 1.41
Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination. Int Immunol (2004) 1.41
Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination. Proc Natl Acad Sci U S A (2005) 1.40
Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nat Struct Mol Biol (2009) 1.40
Megakaryocyte-osteoblast interaction revealed in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Miner Res (2003) 1.39
Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions. Nat Immunol (2010) 1.35
Evidence of a critical architectural function for the RAG proteins in end processing, protection, and joining in V(D)J recombination. Genes Dev (2002) 1.35
The activation-induced deaminase functions in a postcleavage step of the somatic hypermutation process. J Exp Med (2002) 1.34
B cell-specific loss of histone 3 lysine 9 methylation in the V(H) locus depends on Pax5. Nat Immunol (2004) 1.34
Immunopathology of human T cell responses to skin, artery and endothelial cell grafts in the human peripheral blood lymphocyte/severe combined immunodeficient mouse. Springer Semin Immunopathol (2003) 1.29
Osteoporosis with increased osteoclastogenesis in hematopoietic cell-specific STAT3-deficient mice. Biochem Biophys Res Commun (2005) 1.27
T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy. J Bone Miner Res (2006) 1.26
Altered metabolism and lipodystrophy in the early B-cell factor 1-deficient mouse. Endocrinology (2010) 1.24
Promoters, enhancers, and transcription target RAG1 binding during V(D)J recombination. J Exp Med (2010) 1.23
Ebf1-dependent control of the osteoblast and adipocyte lineages. Bone (2008) 1.23
A functional analysis of the spacer of V(D)J recombination signal sequences. PLoS Biol (2003) 1.21
Leaky severe combined immunodeficiency and aberrant DNA rearrangements due to a hypomorphic RAG1 mutation. Blood (2009) 1.19
Regulation of RAG1/RAG2-mediated transposition by GTP and the C-terminal region of RAG2. EMBO J (2003) 1.19
Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Mol Cell (2010) 1.18
Up-regulation of Hlx in immature Th cells induces IFN-gamma expression. J Immunol (2004) 1.18
Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection. J Exp Med (2009) 1.16
Control of gene conversion and somatic hypermutation by immunoglobulin promoter and enhancer sequences. J Exp Med (2006) 1.14
Human trophoblast noncoding RNA suppresses CIITA promoter III activity in murine B-lymphocytes. Biochem Biophys Res Commun (2003) 1.13
Mobilization of RAG-generated signal ends by transposition and insertion in vivo. Mol Cell Biol (2006) 1.12
Ly-6 superfamily members Ly-6A/E, Ly-6C, and Ly-6I recognize two potential ligands expressed by B lymphocytes. J Immunol (2002) 1.10
Histone modifications associated with somatic hypermutation. Immunity (2005) 1.10
Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation. J Immunol (2007) 1.10
Strand-biased spreading of mutations during somatic hypermutation. Science (2007) 1.09
Interleukin-7 influences osteoclast function in vivo but is not a critical factor in ovariectomy-induced bone loss. J Bone Miner Res (2006) 1.06
DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase. Nucleic Acids Res (2003) 1.05
1,25(OH)2 vitamin D3-stimulated osteoclast formation in spleen-osteoblast cocultures is mediated in part by enhanced IL-1 alpha and receptor activator of NF-kappa B ligand production in osteoblasts. J Immunol (2002) 1.05
Extrachromosomal recombination substrates recapitulate beyond 12/23 restricted VDJ recombination in nonlymphoid cells. Immunity (2003) 1.05
Decreased numbers of regulatory T cells suggest impaired immune tolerance in children with tourette syndrome: a preliminary study. Biol Psychiatry (2006) 1.03
Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis. Proc Natl Acad Sci U S A (2008) 1.03
Role of endocrine-immune dysregulation in osteoporosis, sarcopenia, frailty and fracture risk. Mol Aspects Med (2005) 1.03
Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation. Proc Natl Acad Sci U S A (2010) 1.03
RANKL-stimulated osteoclast-like cell formation in vitro is partially dependent on endogenous interleukin-1 production. Bone (2005) 1.02
B cells and osteoblast and osteoclast development. Immunol Rev (2005) 1.02
Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery. J Bone Miner Res (2013) 1.02
Roles of the Ig kappa light chain intronic and 3' enhancers in Igk somatic hypermutation. J Immunol (2006) 1.00
The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases. Mol Cells (2012) 1.00
Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation. J Biol Chem (2008) 1.00
Pax5 and linker histone H1 coordinate DNA methylation and histone modifications in the 3' regulatory region of the immunoglobulin heavy chain locus. Mol Cell Biol (2008) 0.99
Targeting of AID-mediated sequence diversification by cis-acting determinants. Adv Immunol (2007) 0.98
Bcl-2 transduction protects human endothelial cell synthetic microvessel grafts from allogeneic T cells in vivo. J Immunol (2004) 0.97
Reperfusion injury intensifies the adaptive human T cell alloresponse in a human-mouse chimeric artery model. Arterioscler Thromb Vasc Biol (2011) 0.96
Interplay between DNA repair and inflammation, and the link to cancer. Crit Rev Biochem Mol Biol (2014) 0.96
RAG1-DNA binding in V(D)J recombination. Specificity and DNA-induced conformational changes revealed by fluorescence and CD spectroscopy. J Biol Chem (2002) 0.96
Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions. Nat Immunol (2012) 0.95
Receptor activator of NF-kappa B ligand stimulates recruitment of SHP-1 to the complex containing TNFR-associated factor 6 that regulates osteoclastogenesis. J Immunol (2003) 0.95
Interferon-gamma augments CD95(APO-1/Fas) and pro-caspase-8 expression and sensitizes human vascular endothelial cells to CD95-mediated apoptosis. Am J Pathol (2002) 0.95
Parathyroid hormone regulates the distribution and osteoclastogenic potential of hematopoietic progenitors in the bone marrow. J Bone Miner Res (2011) 0.95
Osteoblast-specific overexpression of human interleukin-7 rescues the bone mass phenotype of interleukin-7-deficient female mice. J Bone Miner Res (2012) 0.95
IL-17F deficiency inhibits small intestinal tumorigenesis in ApcMin/+ mice. Biochem Biophys Res Commun (2011) 0.95
How B cells influence bone biology in health and disease. Bone (2010) 0.94
Children with Tourette's syndrome may suffer immunoglobulin A dysgammaglobulinemia: preliminary report. Biol Psychiatry (2009) 0.94
AID and Igh switch region-Myc chromosomal translocations. DNA Repair (Amst) (2006) 0.93
Biphasic effect of prostaglandin E2 on osteoclast formation in spleen cell cultures: role of the EP2 receptor. J Bone Miner Res (2004) 0.93
The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. J Exp Med (2013) 0.93
Immunology. One AID to unite them all. Science (2002) 0.93
Elevated expression of MCP-1, IL-2 and PTPR-N in basal ganglia of Tourette syndrome cases. Brain Behav Immun (2010) 0.93
Imatinib resistance and progression of CML to blast crisis: somatic hypermutation AIDing the way. Cancer Cell (2009) 0.92
Class II transactivator promoter activity is suppressed through regulation by a trophoblast noncoding RNA. Transplantation (2003) 0.92
Non-redundancy of cytidine deaminases in class switch recombination. Eur J Immunol (2004) 0.92
A limited number of genes are involved in the differentiation of germinal center B cells. J Cell Biochem (2006) 0.91
Peroxisome proliferator-activated receptor-γ agonists prevent in vivo remodeling of human artery induced by alloreactive T cells. Circulation (2011) 0.90
Interleukin-7 is a direct inhibitor of in vitro osteoclastogenesis. Endocrinology (2003) 0.90