Lung development and susceptibility to ventilator-induced lung injury.

Brief, large tidal volume ventilation initiates lung injury and a systemic response in fetal sheep. Am J Respir Crit Care Med (2007) 1.73

Pathogenetic significance of biological markers of ventilator-associated lung injury in experimental and clinical studies. Chest (2006) 1.45

Developmental regulation of NO-mediated VEGF-induced effects in the lung. Am J Respir Cell Mol Biol (2008) 1.10

Postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia. Birth Defects Res A Clin Mol Teratol (2014) 1.08

Targeting inflammation to prevent bronchopulmonary dysplasia: can new insights be translated into therapies? Pediatrics (2011) 1.08

Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation. Am J Respir Crit Care Med (2007) 1.07

Recent advances and new opportunities in lung mechanobiology. J Biomech (2009) 1.06

Ventilator-induced lung injury. Similarity and differences between children and adults. Am J Respir Crit Care Med (2014) 0.97

Understanding the Impact of Infection, Inflammation, and Their Persistence in the Pathogenesis of Bronchopulmonary Dysplasia. Front Med (Lausanne) (2015) 0.88

Effects of age on the synergistic interactions between lipopolysaccharide and mechanical ventilation in mice. Am J Respir Cell Mol Biol (2009) 0.87

Pediatric Sepsis - Part I: "Children are not small adults!" Open Inflamm J (2011) 0.87

Susceptibility to ventilator induced lung injury is increased in senescent rats. Crit Care (2013) 0.83

Animal Models, Learning Lessons to Prevent and Treat Neonatal Chronic Lung Disease. Front Med (Lausanne) (2015) 0.82

Donor age and early graft failure after lung transplantation: a cohort study. Am J Transplant (2013) 0.77

Respiratory mechanics and lung stress/strain in children with acute respiratory distress syndrome. Ann Intensive Care (2016) 0.76

Interpretation of PV Curves. Am J Respir Crit Care Med (2005) 0.75

Disassociating Lung Mechanics and Oxygenation in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med (2017) 0.75

Incidence, risk factors and consequences of ICU delirium. Intensive Care Med (2006) 4.82

Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med (2014) 3.96

Hypocapnia. N Engl J Med (2002) 2.67

The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65

Angiopoietin-1 and angiopoietin-2 as clinically informative prognostic biomarkers of morbidity and mortality in severe sepsis. Crit Care Med (2011) 2.59

Atelectasis causes alveolar injury in nonatelectatic lung regions. Am J Respir Crit Care Med (2006) 2.56

Seizure burden is independently associated with short term outcome in critically ill children. Brain (2014) 2.54

Hypocapnia and the injured brain: more harm than benefit. Crit Care Med (2010) 2.35

Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med (2003) 2.31

Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol (2006) 2.30

Lung-protective ventilation in the operating room: time to implement? Anesthesiology (2014) 2.15

Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates. Anesth Analg (2010) 2.09

C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature (2007) 2.06

Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med (2003) 2.03

Molecular evidence of placental hypoxia in preeclampsia. J Clin Endocrinol Metab (2005) 1.98

A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (2005) 1.93

Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol (2009) 1.85

Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia? Circ Res (2004) 1.83

Insulin-like growth factor-I receptor-mediated vasculogenesis/angiogenesis in human lung development. Am J Respir Cell Mol Biol (2003) 1.80

Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis. Crit Care Med (2010) 1.78

Bronchopulmonary dysplasia: one disease or two? Am J Respir Crit Care Med (2003) 1.73

Negative-pressure ventilation: better oxygenation and less lung injury. Am J Respir Crit Care Med (2007) 1.71

Effect of chemical stabilizers of hypoxia-inducible factors on early lung development. Am J Physiol Lung Cell Mol Physiol (2007) 1.68

Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. Reg Anesth Pain Med (2010) 1.67

Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition. Crit Care Med (2012) 1.63

Pulmonary hypertension in adult Alk1 heterozygous mice due to oxidative stress. Cardiovasc Res (2011) 1.59

Pulmonary atelectasis: a pathogenic perioperative entity. Anesthesiology (2005) 1.57

Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Carcinogenesis (2003) 1.56

Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1. Proc Natl Acad Sci U S A (2004) 1.56

Novel method to quantify loss of heart rate variability in pediatric multiple organ failure. Crit Care Med (2003) 1.54

Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med (2011) 1.52

Glucose in the ICU--evidence, guidelines, and outcomes. N Engl J Med (2012) 1.52

Emergency airway management: competence versus expertise? Anesthesiology (2008) 1.49

Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med (2013) 1.48

Dissociation of inflammatory mediators and function: experimental lung injury in nonpulmonary sepsis. Crit Care Med (2013) 1.48

Continuous negative abdominal distension augments recruitment of atelectatic lung. Crit Care Med (2012) 1.46

Delayed childbearing and its impact on population rate changes in lower birth weight, multiple birth, and preterm delivery. Pediatrics (2002) 1.46

Clinical impact of vasopressin infusion on hemodynamics, liver and renal function in pediatric patients. Intensive Care Med (2008) 1.46

Nonbeneficial treatment Canada: definitions, causes, and potential solutions from the perspective of healthcare practitioners*. Crit Care Med (2015) 1.45

Mechanical ventilation induces neutrophil extracellular trap formation. Anesthesiology (2015) 1.44

Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU. Pediatr Crit Care Med (2016) 1.40

Pediatric Hematopoietic Stem Cell Transplant and Intensive Care: Have Things Changed? Pediatr Crit Care Med (2016) 1.39

Airway management in the lateral position: a randomized controlled trial. Anesth Analg (2005) 1.37

Opposing effects of 60% oxygen and neutrophil influx on alveologenesis in the neonatal rat. Am J Respir Crit Care Med (2004) 1.31

Grg1 acts as a lung-specific oncogene in a transgenic mouse model. Cancer Res (2006) 1.31

Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech (2014) 1.30

Bench-to-bedside review: carbon dioxide. Crit Care (2010) 1.29

Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung. Am J Physiol Lung Cell Mol Physiol (2004) 1.29

Lung inflammation as a therapeutic target in cystic fibrosis. Am J Respir Cell Mol Biol (2004) 1.28

Asymmetric dimethylarginine is increased in asthma. Am J Respir Crit Care Med (2011) 1.25

Quantifying the volume of documented clinical information in critical illness. J Crit Care (2007) 1.24

Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med (2003) 1.20

Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med (2007) 1.20

PRIME importance of pathology expertise. Nat Biotechnol (2009) 1.19

Mouse snail is a target gene for HIF. Mol Cancer Res (2011) 1.18

Stretch-activated signaling pathways responsible for early response gene expression in fetal lung epithelial cells. J Cell Physiol (2007) 1.18

Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats. Am J Physiol Lung Cell Mol Physiol (2007) 1.17

Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation. Neonatology (2009) 1.16

Conversion of mechanical force into biochemical signaling. J Biol Chem (2004) 1.15

N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. J Biol Chem (2007) 1.14

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation. Cell Res (2008) 1.13

Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11

Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat. Am J Physiol Lung Cell Mol Physiol (2006) 1.11

Human placental hypoxia-inducible factor-1alpha expression correlates with clinical outcomes in chronic hypoxia in vivo. Am J Pathol (2007) 1.11

Similarities and dissimilarities of branching and septation during lung development. Pediatr Pulmonol (2005) 1.11

Permissive hypercapnia--role in protective lung ventilatory strategies. Intensive Care Med (2004) 1.10

Dynamic HIF1A regulation during human placental development. Biol Reprod (2006) 1.08

Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. J Biol Chem (2003) 1.08

Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. Am J Physiol Lung Cell Mol Physiol (2007) 1.06

Detection of modifier loci influencing the lung phenotype of cystic fibrosis knockout mice. Mamm Genome (2002) 1.06

Surfactant lipid synthesis and lamellar body formation in glycogen-laden type II cells. Am J Physiol Lung Cell Mol Physiol (2004) 1.05

Sperm freezing and in vitro fertilization in three substrains of C57BL/6 mice. J Am Assoc Lab Anim Sci (2009) 1.05

Prenatal exposure to fluoxetine induces fetal pulmonary hypertension in the rat. Am J Respir Crit Care Med (2007) 1.05

The mouse pathology ontology, MPATH; structure and applications. J Biomed Semantics (2013) 1.05

Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction. J Clin Endocrinol Metab (2007) 1.05