Published in Am J Respir Crit Care Med on May 04, 2006
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Lung regional metabolic activity and gas volume changes induced by tidal ventilation in patients with acute lung injury. Am J Respir Crit Care Med (2011) 1.84
Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med (2013) 1.48
Mechanical ventilation with high tidal volume induces inflammation in patients without lung disease. Crit Care (2010) 1.22
Mild endotoxemia during mechanical ventilation produces spatially heterogeneous pulmonary neutrophilic inflammation in sheep. Anesthesiology (2010) 1.20
Recent advances and new opportunities in lung mechanobiology. J Biomech (2009) 1.06
Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care (2013) 1.03
Quantitative imaging of alveolar recruitment with hyperpolarized gas MRI during mechanical ventilation. J Appl Physiol (1985) (2010) 1.02
Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation. J Appl Physiol (1985) (2011) 0.97
Cell wounding and repair in ventilator injured lungs. Respir Physiol Neurobiol (2008) 0.96
Positive end-expiratory pressure alters the severity and spatial heterogeneity of ventilator-induced lung injury: an argument for cyclical airway collapse. J Crit Care (2008) 0.89
Airway strain during mechanical ventilation in an intact animal model. Am J Respir Crit Care Med (2007) 0.87
Comparative Effects of Volutrauma and Atelectrauma on Lung Inflammation in Experimental Acute Respiratory Distress Syndrome. Crit Care Med (2016) 0.86
Small airway remodeling in acute respiratory distress syndrome: a study in autopsy lung tissue. Crit Care (2011) 0.85
Bench-to-bedside review: distal airways in acute respiratory distress syndrome. Crit Care (2007) 0.85
Non-lobar atelectasis generates inflammation and structural alveolar injury in the surrounding healthy tissue during mechanical ventilation. Crit Care (2014) 0.84
Positive end-expiratory pressure increments during anesthesia in normal lung result in hysteresis and greater numbers of smaller aerated airspaces. Anesthesiology (2013) 0.80
Lung ventilation injures areas with discrete alveolar flooding, in a surface tension-dependent fashion. J Appl Physiol (1985) (2014) 0.80
Visualizing the Propagation of Acute Lung Injury. Anesthesiology (2016) 0.78
Spatial distribution of sequential ventilation during mechanical ventilation of the uninjured lung: an argument for cyclical airway collapse and expansion. BMC Pulm Med (2010) 0.77
Ventilator-induced lung injury distribution: the key to understanding injury mechanisms. Am J Respir Crit Care Med (2007) 0.77
Perioperative lung-protective ventilation strategy reduces postoperative pulmonary complications in patients undergoing thoracic and major abdominal surgery. Korean J Anesthesiol (2016) 0.75
Atelectasis causes alveolar hypoxia-induced inflammation during uneven mechanical ventilation in rats. Intensive Care Med Exp (2015) 0.75
Mild loss of lung aeration augments stretch in healthy lung regions. J Appl Physiol (1985) (2015) 0.75
Pendrin, an anion exchanger on lung epithelial cells, could be a novel target for lipopolysaccharide-induced acute lung injury mice. Am J Transl Res (2016) 0.75
Fifty Years of Research in ARDS. Setting Positive End-expiratory Pressure in the Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med (2017) 0.75
Alveolar instability (atelectrauma) is not identified by arterial oxygenation predisposing the development of an occult ventilator-induced lung injury. Intensive Care Med Exp (2015) 0.75
Intravascular oxygen sensors with novel applications for bedside respiratory monitoring. Anaesthesia (2017) 0.75
Interpreting lung functional changes. Am J Respir Crit Care Med (2007) 0.75
Lung metabolism during ventilator-induced lung injury: stretching the relevance of the normally aerated lung*. Crit Care Med (2014) 0.75
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med (2009) 4.97
Incidence, risk factors and consequences of ICU delirium. Intensive Care Med (2006) 4.82
Cast versus splint in children with minimally angulated fractures of the distal radius: a randomized controlled trial. CMAJ (2010) 3.15
Hypocapnia. N Engl J Med (2002) 2.67
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
Seizure burden is independently associated with short term outcome in critically ill children. Brain (2014) 2.54
Hypocapnia and the injured brain: more harm than benefit. Crit Care Med (2010) 2.35
Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med (2003) 2.31
Hypercapnic acidosis attenuates endotoxin-induced acute lung injury. Am J Respir Crit Care Med (2003) 2.31
Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol (2006) 2.30
Lung-protective ventilation in the operating room: time to implement? Anesthesiology (2014) 2.15
Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates. Anesth Analg (2010) 2.09
C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature (2007) 2.06
Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med (2003) 2.03
Molecular evidence of placental hypoxia in preeclampsia. J Clin Endocrinol Metab (2005) 1.98
Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury. Crit Care Med (2008) 1.93
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (2005) 1.93
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol (2009) 1.85
Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia? Circ Res (2004) 1.83
Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ Res (2005) 1.81
Insulin-like growth factor-I receptor-mediated vasculogenesis/angiogenesis in human lung development. Am J Respir Cell Mol Biol (2003) 1.80
Negative-pressure ventilation: better oxygenation and less lung injury. Am J Respir Crit Care Med (2007) 1.71
Effect of chemical stabilizers of hypoxia-inducible factors on early lung development. Am J Physiol Lung Cell Mol Physiol (2007) 1.68
Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. Reg Anesth Pain Med (2010) 1.67
Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition. Crit Care Med (2012) 1.63
Lung development and susceptibility to ventilator-induced lung injury. Am J Respir Crit Care Med (2005) 1.62
Pulmonary atelectasis: a pathogenic perioperative entity. Anesthesiology (2005) 1.57
Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Carcinogenesis (2003) 1.56
Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1. Proc Natl Acad Sci U S A (2004) 1.56
Novel method to quantify loss of heart rate variability in pediatric multiple organ failure. Crit Care Med (2003) 1.54
Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med (2011) 1.52
Glucose in the ICU--evidence, guidelines, and outcomes. N Engl J Med (2012) 1.52
Emergency airway management: competence versus expertise? Anesthesiology (2008) 1.49
Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med (2013) 1.48
Dissociation of inflammatory mediators and function: experimental lung injury in nonpulmonary sepsis. Crit Care Med (2013) 1.48
Exercise-related changes in umbilical and uterine artery waveforms as assessed by Doppler ultrasound scans. Am J Obstet Gynecol (2002) 1.47
Continuous negative abdominal distension augments recruitment of atelectatic lung. Crit Care Med (2012) 1.46
Clinical impact of vasopressin infusion on hemodynamics, liver and renal function in pediatric patients. Intensive Care Med (2008) 1.46
Mechanical ventilation induces neutrophil extracellular trap formation. Anesthesiology (2015) 1.44
Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU. Pediatr Crit Care Med (2016) 1.40
Pediatric Hematopoietic Stem Cell Transplant and Intensive Care: Have Things Changed? Pediatr Crit Care Med (2016) 1.39
Adult ovarian retinoblastoma genomic profile distinct from prior childhood eye tumor. Arch Ophthalmol (2011) 1.39
Statistics: all together now, one step at a time. Microcirculation (2011) 1.38
Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation. J Physiol (2002) 1.38
Airway management in the lateral position: a randomized controlled trial. Anesth Analg (2005) 1.37
The structural basis of pulmonary hypertension in chronic lung disease: remodelling, rarefaction or angiogenesis? J Anat (2002) 1.35
Opposing effects of 60% oxygen and neutrophil influx on alveologenesis in the neonatal rat. Am J Respir Crit Care Med (2004) 1.31
Grg1 acts as a lung-specific oncogene in a transgenic mouse model. Cancer Res (2006) 1.31
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech (2014) 1.30
Bench-to-bedside review: carbon dioxide. Crit Care (2010) 1.29
Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung. Am J Physiol Lung Cell Mol Physiol (2004) 1.29
Quantifying the volume of documented clinical information in critical illness. J Crit Care (2007) 1.24
Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med (2003) 1.20
Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med (2007) 1.20
PRIME importance of pathology expertise. Nat Biotechnol (2009) 1.19
A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease. Gastroenterology (2005) 1.19
Mouse snail is a target gene for HIF. Mol Cancer Res (2011) 1.18
Stretch-activated signaling pathways responsible for early response gene expression in fetal lung epithelial cells. J Cell Physiol (2007) 1.18
Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation. Neonatology (2009) 1.16
Conversion of mechanical force into biochemical signaling. J Biol Chem (2004) 1.15
Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol (2008) 1.15
Evaluation of the utility of radiography in acute bronchiolitis. J Pediatr (2007) 1.14
N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. J Biol Chem (2007) 1.14
Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation. Cell Res (2008) 1.13
Serum lipids, glucose homeostasis and abdominal adipose tissue distribution in protease inhibitor-treated and naive HIV-infected children. AIDS (2003) 1.12
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells. J Immunol (2010) 1.12
Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11
Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat. Am J Physiol Lung Cell Mol Physiol (2006) 1.11
Human placental hypoxia-inducible factor-1alpha expression correlates with clinical outcomes in chronic hypoxia in vivo. Am J Pathol (2007) 1.11
Similarities and dissimilarities of branching and septation during lung development. Pediatr Pulmonol (2005) 1.11
Gremlin plays a key role in the pathogenesis of pulmonary hypertension. Circulation (2012) 1.11
Permissive hypercapnia--role in protective lung ventilatory strategies. Intensive Care Med (2004) 1.10
Children hospitalized with severe acute respiratory syndrome-related illness in Toronto. Pediatrics (2003) 1.10
The pathophysiological basis of chronic hypoxic pulmonary hypertension in the mouse: vasoconstrictor and structural mechanisms contribute equally. Exp Physiol (2012) 1.08