Negative-pressure ventilation: better oxygenation and less lung injury.

Negative- versus positive-pressure ventilation in intubated patients with acute respiratory distress syndrome. Crit Care (2012) 0.85

Relative effects of negative versus positive pressure ventilation depend on applied conditions. Intensive Care Med (2012) 0.84

Year in review in Intensive Care Medicine 2012: I. Neurology and neurointensive care, epidemiology and nephrology, biomarkers and inflammation, nutrition, experimentals. Intensive Care Med (2012) 0.84

Use of dynamic CT in acute respiratory distress syndrome (ARDS) with comparison of positive and negative pressure ventilation. Eur Radiol (2008) 0.81

Design and validation of a clinical-scale bioreactor for long-term isolated lung culture. Biomaterials (2015) 0.81

Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ. Respir Res (2016) 0.75

Effects of extrathoracic mechanical ventilation on pulmonary hypertension secondary to lung disease. J Anesth (2016) 0.75

Proceedings of the fourth international conference on central hypoventilation. Orphanet J Rare Dis (2014) 0.75

Year in review 2012: Critical Care--Respirology. Crit Care (2013) 0.75

Do spontaneous and mechanical breathing have similar effects on average transpulmonary and alveolar pressure? A clinical crossover study. Crit Care (2016) 0.75

Whole-body "negative-pressure" ventilation: is it really different? Am J Respir Crit Care Med (2008) 0.75

Combined Negative- and Positive-Pressure Ventilation for the Treatment of ARDS. Case Rep Crit Care (2015) 0.75

Biphasic cuirass ventilation for treatment of an air leak after pneumothorax in a patient with nemaline myopathy: a case report. J Anesth (2016) 0.75

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med (2009) 4.97

Incidence, risk factors and consequences of ICU delirium. Intensive Care Med (2006) 4.82

Cast versus splint in children with minimally angulated fractures of the distal radius: a randomized controlled trial. CMAJ (2010) 3.15

Hypocapnia. N Engl J Med (2002) 2.67

The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65

Atelectasis causes alveolar injury in nonatelectatic lung regions. Am J Respir Crit Care Med (2006) 2.56

Seizure burden is independently associated with short term outcome in critically ill children. Brain (2014) 2.54

Hypocapnia and the injured brain: more harm than benefit. Crit Care Med (2010) 2.35

Carbon dioxide attenuates pulmonary impairment resulting from hyperventilation. Crit Care Med (2003) 2.31

Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. J Am Coll Cardiol (2006) 2.30

Lung-protective ventilation in the operating room: time to implement? Anesthesiology (2014) 2.15

Protocolized intensive care unit management of analgesia, sedation, and delirium improves analgesia and subsyndromal delirium rates. Anesth Analg (2010) 2.09

C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a. Nature (2007) 2.06

Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med (2003) 2.03

Molecular evidence of placental hypoxia in preeclampsia. J Clin Endocrinol Metab (2005) 1.98

A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (2005) 1.93

Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning. PLoS Biol (2009) 1.85

Defective lung vascular development and fatal respiratory distress in endothelial NO synthase-deficient mice: a model of alveolar capillary dysplasia? Circ Res (2004) 1.83

Insulin-like growth factor-I receptor-mediated vasculogenesis/angiogenesis in human lung development. Am J Respir Cell Mol Biol (2003) 1.80

Effect of chemical stabilizers of hypoxia-inducible factors on early lung development. Am J Physiol Lung Cell Mol Physiol (2007) 1.68

Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. Reg Anesth Pain Med (2010) 1.67

Mechanical stress induces lung fibrosis by epithelial-mesenchymal transition. Crit Care Med (2012) 1.63

Lung development and susceptibility to ventilator-induced lung injury. Am J Respir Crit Care Med (2005) 1.62

Pulmonary atelectasis: a pathogenic perioperative entity. Anesthesiology (2005) 1.57

Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Carcinogenesis (2003) 1.56

Control of late off-center cone bipolar cell differentiation and visual signaling by the homeobox gene Vsx1. Proc Natl Acad Sci U S A (2004) 1.56

Novel method to quantify loss of heart rate variability in pediatric multiple organ failure. Crit Care Med (2003) 1.54

Airway pressure release ventilation improves pulmonary blood flow in infants after cardiac surgery. Crit Care Med (2011) 1.52

Glucose in the ICU--evidence, guidelines, and outcomes. N Engl J Med (2012) 1.52

Emergency airway management: competence versus expertise? Anesthesiology (2008) 1.49

Imaging the interaction of atelectasis and overdistension in surfactant-depleted lungs. Crit Care Med (2013) 1.48

Dissociation of inflammatory mediators and function: experimental lung injury in nonpulmonary sepsis. Crit Care Med (2013) 1.48

Continuous negative abdominal distension augments recruitment of atelectatic lung. Crit Care Med (2012) 1.46

Clinical impact of vasopressin infusion on hemodynamics, liver and renal function in pediatric patients. Intensive Care Med (2008) 1.46

Mechanical ventilation induces neutrophil extracellular trap formation. Anesthesiology (2015) 1.44

Strategies to Maximize Enrollment in a Prospective Study of Comatose Children in the PICU. Pediatr Crit Care Med (2016) 1.40

Adult ovarian retinoblastoma genomic profile distinct from prior childhood eye tumor. Arch Ophthalmol (2011) 1.39

Pediatric Hematopoietic Stem Cell Transplant and Intensive Care: Have Things Changed? Pediatr Crit Care Med (2016) 1.39

Airway management in the lateral position: a randomized controlled trial. Anesth Analg (2005) 1.37

Opposing effects of 60% oxygen and neutrophil influx on alveologenesis in the neonatal rat. Am J Respir Crit Care Med (2004) 1.31

Grg1 acts as a lung-specific oncogene in a transgenic mouse model. Cancer Res (2006) 1.31

Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. Dis Model Mech (2014) 1.30

Bench-to-bedside review: carbon dioxide. Crit Care (2010) 1.29

Role of oxygen and vascular development in epithelial branching morphogenesis of the developing mouse lung. Am J Physiol Lung Cell Mol Physiol (2004) 1.29

Quantifying the volume of documented clinical information in critical illness. J Crit Care (2007) 1.24

Atelectasis causes vascular leak and lethal right ventricular failure in uninjured rat lungs. Am J Respir Crit Care Med (2003) 1.20

Have changes in ventilation practice improved outcome in children with acute lung injury? Pediatr Crit Care Med (2007) 1.20

PRIME importance of pathology expertise. Nat Biotechnol (2009) 1.19

Stretch-activated signaling pathways responsible for early response gene expression in fetal lung epithelial cells. J Cell Physiol (2007) 1.18

Mouse snail is a target gene for HIF. Mol Cancer Res (2011) 1.18

Congenital diaphragmatic hernia: comparison of animal models and relevance to the human situation. Neonatology (2009) 1.16

Conversion of mechanical force into biochemical signaling. J Biol Chem (2004) 1.15

Evaluation of the utility of radiography in acute bronchiolitis. J Pediatr (2007) 1.14

N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. J Biol Chem (2007) 1.14

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation. Cell Res (2008) 1.13

Serum lipids, glucose homeostasis and abdominal adipose tissue distribution in protease inhibitor-treated and naive HIV-infected children. AIDS (2003) 1.12

Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med (2014) 1.11

Therapeutic hypercapnia prevents chronic hypoxia-induced pulmonary hypertension in the newborn rat. Am J Physiol Lung Cell Mol Physiol (2006) 1.11

Human placental hypoxia-inducible factor-1alpha expression correlates with clinical outcomes in chronic hypoxia in vivo. Am J Pathol (2007) 1.11

Similarities and dissimilarities of branching and septation during lung development. Pediatr Pulmonol (2005) 1.11

Permissive hypercapnia--role in protective lung ventilatory strategies. Intensive Care Med (2004) 1.10

Children hospitalized with severe acute respiratory syndrome-related illness in Toronto. Pediatrics (2003) 1.10

Dynamic HIF1A regulation during human placental development. Biol Reprod (2006) 1.08

Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. J Biol Chem (2003) 1.08

Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. Am J Physiol Lung Cell Mol Physiol (2007) 1.06

Detection of modifier loci influencing the lung phenotype of cystic fibrosis knockout mice. Mamm Genome (2002) 1.06

Insulin sensitivity and beta-cell function in protease inhibitor-treated and -naive human immunodeficiency virus-infected children. J Clin Endocrinol Metab (2004) 1.06

Surfactant lipid synthesis and lamellar body formation in glycogen-laden type II cells. Am J Physiol Lung Cell Mol Physiol (2004) 1.05

Sperm freezing and in vitro fertilization in three substrains of C57BL/6 mice. J Am Assoc Lab Anim Sci (2009) 1.05

The mouse pathology ontology, MPATH; structure and applications. J Biomed Semantics (2013) 1.05

Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction. J Clin Endocrinol Metab (2007) 1.05

High tidal volume ventilation causes different inflammatory responses in newborn versus adult lung. Am J Respir Crit Care Med (2004) 1.04

Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care (2013) 1.03

Lung-derived soluble mediators are pathogenic in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2011) 1.03