Published in PLoS One on January 27, 2010
Uridine insertion/deletion editing in trypanosomes: a playground for RNA-guided information transfer. Wiley Interdiscip Rev RNA (2011) 1.29
TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites. RNA (2010) 1.11
MRB3010 is a core component of the MRB1 complex that facilitates an early step of the kinetoplastid RNA editing process. RNA (2011) 1.01
Naphthalene-based RNA editing inhibitor blocks RNA editing activities and editosome assembly in Trypanosoma brucei. J Biol Chem (2011) 0.87
Editosome accessory factors KREPB9 and KREPB10 in Trypanosoma brucei. Eukaryot Cell (2012) 0.85
U-Insertion/Deletion mRNA-Editing Holoenzyme: Definition in Sight. Trends Parasitol (2015) 0.84
Differential Editosome Protein Function between Life Cycle Stages of Trypanosoma brucei. J Biol Chem (2015) 0.81
Inhibitors of RNA editing as potential chemotherapeutics against trypanosomatid pathogens. Int J Parasitol Drugs Drug Resist (2011) 0.81
High-throughput sequencing of partially edited trypanosome mRNAs reveals barriers to editing progression and evidence for alternative editing. RNA (2016) 0.78
Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds. J Struct Biol (2012) 0.78
In vivo cleavage specificity of Trypanosoma brucei editosome endonucleases. Nucleic Acids Res (2017) 0.75
A model for RNA editing in kinetoplastid mitochondria: "guide" RNA molecules transcribed from maxicircle DNA provide the edited information. Cell (1990) 6.24
Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA. Cell (1986) 5.49
Nucleic acid recognition by OB-fold proteins. Annu Rev Biophys Biomol Struct (2003) 4.13
Complex management: RNA editing in trypanosomes. Trends Biochem Sci (2005) 3.69
An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei. Science (2001) 3.52
Extensive editing of the cytochrome c oxidase III transcript in Trypanosoma brucei. Cell (1988) 3.26
RNA editing in kinetoplastid protozoa. Microbiol Mol Biol Rev (1997) 2.58
Three classes of C2H2 zinc finger proteins. Cell Mol Life Sci (2001) 2.44
Developmentally regulated addition of nucleotides within apocytochrome b transcripts in Trypanosoma brucei. Cell (1987) 2.43
RNA editing involves indiscriminate U changes throughout precisely defined editing domains. Cell (1990) 2.40
An extensively edited mitochondrial transcript in kinetoplastids encodes a protein homologous to ATPase subunit 6. Cell (1990) 2.38
Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons. Cell (1988) 2.32
Trypanosoma brucei gBP21. An arginine-rich mitochondrial protein that binds to guide RNA with high affinity. J Biol Chem (1997) 2.17
Isolation of a U-insertion/deletion editing complex from Leishmania tarentolae mitochondria. EMBO J (2003) 2.12
Mitochondrial proteins and complexes in Leishmania and Trypanosoma involved in U-insertion/deletion RNA editing. RNA (2004) 2.06
Unexplained complexity of the mitochondrial genome and transcriptome in kinetoplastid flagellates. Curr Genet (2005) 2.01
The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing. Cell (1992) 1.99
Four related proteins of the Trypanosoma brucei RNA editing complex. Mol Cell Biol (2001) 1.97
An essential RNase III insertion editing endonuclease in Trypanosoma brucei. Proc Natl Acad Sci U S A (2005) 1.96
Keep your fingers off my DNA: protein-protein interactions mediated by C2H2 zinc finger domains. Cell Biochem Biophys (2008) 1.95
Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol Cell (2003) 1.94
TbMP57 is a 3' terminal uridylyl transferase (TUTase) of the Trypanosoma brucei editosome. Mol Cell (2003) 1.88
RNA editing in Trypanosoma brucei requires three different editosomes. Mol Cell Biol (2007) 1.87
Trypanosoma brucei TBRGG1, a mitochondrial oligo(U)-binding protein that co-localizes with an in vitro RNA editing activity. J Biol Chem (1998) 1.87
A tale of two TUTases. Proc Natl Acad Sci U S A (2003) 1.87
Compositionally and functionally distinct editosomes in Trypanosoma brucei. RNA (2006) 1.86
Editing machines: the complexities of trypanosome RNA editing. Cell (2002) 1.75
The MURF3 gene of T. brucei contains multiple domains of extensive editing and is homologous to a subunit of NADH dehydrogenase. Cell (1990) 1.68
RNA editing in trypanosomes. Eur J Biochem (1994) 1.68
Extensive editing of both processed and preprocessed maxicircle CR6 transcripts in Trypanosoma brucei. J Biol Chem (1992) 1.64
Kinetoplast DNA network: evolution of an improbable structure. Eukaryot Cell (2002) 1.62
RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei. J Biol Chem (2004) 1.58
A deletion site editing endonuclease in Trypanosoma brucei. Mol Cell (2005) 1.57
Creation of AUG initiation codons by addition of uridines within cytochrome b transcripts of kinetoplastids. Proc Natl Acad Sci U S A (1988) 1.54
RBP16 is a multifunctional gene regulatory protein involved in editing and stabilization of specific mitochondrial mRNAs in Trypanosoma brucei. RNA (2003) 1.53
Comparative analysis of editosome proteins in trypanosomatids. Nucleic Acids Res (2003) 1.52
Characterization of cytochrome c oxidase III transcripts that are edited only in the 3' region. Cell (1988) 1.52
Distinct functions of two RNA ligases in active Trypanosoma brucei RNA editing complexes. Mol Cell Biol (2002) 1.48
TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex. RNA (2008) 1.47
Reconstitution of uridine-deletion precleaved RNA editing with two recombinant enzymes. Proc Natl Acad Sci U S A (2005) 1.47
Partially edited mRNAs for cytochrome b and subunit III of cytochrome oxidase from Leishmania tarentolae mitochondria: RNA editing intermediates. Cell (1990) 1.46
The involvement of gRNA-binding protein gBP21 in RNA editing-an in vitro and in vivo analysis. Nucleic Acids Res (1999) 1.45
TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei. Eukaryot Cell (2003) 1.39
TbRGG2, an essential RNA editing accessory factor in two Trypanosoma brucei life cycle stages. J Biol Chem (2008) 1.33
TbMP42, a protein component of the RNA editing complex in African trypanosomes, has endo-exoribonuclease activity. Mol Cell (2005) 1.33
Conserved genes encode guide RNAs in mitochondria of Crithidia fasciculata. EMBO J (1991) 1.29
Alternative editing of cytochrome c oxidase III mRNA in trypanosome mitochondria generates protein diversity. EMBO Rep (2006) 1.22
RNA editing-associated protein 1 is an RNA binding protein with specificity for preedited mRNA. Mol Cell (2001) 1.22
KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2006) 1.19
Processing of polycistronic guide RNAs is associated with RNA editing complexes in Trypanosoma brucei. EMBO J (2000) 1.19
KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2007) 1.14
RNA uridylyltransferases. Cell Mol Life Sci (2005) 1.14
Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins. Proc Natl Acad Sci U S A (2006) 1.11
A protein-protein interaction map of trypanosome ~20S editosomes. J Biol Chem (2009) 1.08
An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei. RNA (2007) 1.08
gRNA/pre-mRNA annealing and RNA chaperone activities of RBP16. RNA (2008) 1.06
Differential functions of two editosome exoUases in Trypanosoma brucei. RNA (2009) 1.06
RBP16 stimulates trypanosome RNA editing in vitro at an early step in the editing reaction. RNA (2006) 1.06
Distinct and overlapping functions of MRP1/2 and RBP16 in mitochondrial RNA metabolism. Mol Cell Biol (2009) 1.04
Uridine insertion/deletion RNA editing in trypanosomatid mitochondria: In search of the editosome. RNA (2009) 1.02
OB-fold: growing bigger with functional consistency. Curr Protein Pept Sci (2003) 1.02
Alternative RNA editing produces a novel protein involved in mitochondrial DNA maintenance in trypanosomes. Mol Cell Biol (2008) 1.01
Alternative mRNA editing in trypanosomes is extensive and may contribute to mitochondrial protein diversity. PLoS One (2008) 1.00
The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol (2008) 0.99
Dyskinetoplastic Trypanosoma brucei contains functional editing complexes. Eukaryot Cell (2003) 0.99
RNA editing in trypanosomes. The us(e) of guide RNAs. Mol Biol Rep (1992) 0.96
An intragenic guide RNA location suggests a complex mechanism for mitochondrial gene expression in Trypanosoma brucei. Eukaryot Cell (2004) 0.96
The 3'-untranslated region of cytochrome oxidase II mRNA functions in RNA editing of African trypanosomes exclusively as a cis guide RNA. RNA (2004) 0.95
In Trypanosoma brucei RNA editing, TbMP18 (band VII) is critical for editosome integrity and for both insertional and deletional cleavages. Mol Cell Biol (2006) 0.92
PyCogent: a toolkit for making sense from sequence. Genome Biol (2007) 20.64
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science (2005) 7.61
Comparative genomics of trypanosomatid parasitic protozoa. Science (2005) 5.37
Complex management: RNA editing in trypanosomes. Trends Biochem Sci (2005) 3.69
An essential RNase III insertion editing endonuclease in Trypanosoma brucei. Proc Natl Acad Sci U S A (2005) 1.96
Separate insertion and deletion subcomplexes of the Trypanosoma brucei RNA editing complex. Mol Cell (2003) 1.94
A comprehensive analysis of Trypanosoma brucei mitochondrial proteome. Proteomics (2009) 1.94
Compositionally and functionally distinct editosomes in Trypanosoma brucei. RNA (2006) 1.86
Mitochondrial complexes in Trypanosoma brucei: a novel complex and a unique oxidoreductase complex. Mol Cell Proteomics (2007) 1.81
Discovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei. Proc Natl Acad Sci U S A (2008) 1.73
High resolution crystal structure of a key editosome enzyme from Trypanosoma brucei: RNA editing ligase 1. J Mol Biol (2004) 1.67
Structural basis for UTP specificity of RNA editing TUTases from Trypanosoma brucei. EMBO J (2005) 1.61
RNA interference analyses suggest a transcript-specific regulatory role for mitochondrial RNA-binding proteins MRP1 and MRP2 in RNA editing and other RNA processing in Trypanosoma brucei. J Biol Chem (2004) 1.58
A deletion site editing endonuclease in Trypanosoma brucei. Mol Cell (2005) 1.57
Role of uridylate-specific exoribonuclease activity in Trypanosoma brucei RNA editing. Eukaryot Cell (2002) 1.55
TbRGG1, an essential protein involved in kinetoplastid RNA metabolism that is associated with a novel multiprotein complex. RNA (2008) 1.47
TbMP44 is essential for RNA editing and structural integrity of the editosome in Trypanosoma brucei. Eukaryot Cell (2003) 1.39
A novel active DNA topoisomerase I in Leishmania donovani. J Biol Chem (2002) 1.35
Leishmania major chromosome 3 contains two long convergent polycistronic gene clusters separated by a tRNA gene. Nucleic Acids Res (2003) 1.29
The MRB1 complex functions in kinetoplastid RNA processing. RNA (2008) 1.24
Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum. Proc Natl Acad Sci U S A (2013) 1.21
KREPA4, an RNA binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2006) 1.19
KREPA6 is an RNA-binding protein essential for editosome integrity and survival of Trypanosoma brucei. RNA (2007) 1.14
The F(0)F(1)-ATP synthase complex contains novel subunits and is essential for procyclic Trypanosoma brucei. PLoS Pathog (2009) 1.14
Evaluation of differential gene expression in Leishmania major Friedlin procyclics and metacyclics using DNA microarray analysis. Mol Biochem Parasitol (2003) 1.11
A protein-protein interaction map of trypanosome ~20S editosomes. J Biol Chem (2009) 1.08
An essential role of KREPB4 in RNA editing and structural integrity of the editosome in Trypanosoma brucei. RNA (2007) 1.08
Differential functions of two editosome exoUases in Trypanosoma brucei. RNA (2009) 1.06
Isolation and compositional analysis of trypanosomatid editosomes. Methods Enzymol (2007) 1.03
Genomic organization and gene expression in a chromosomal region of Leishmania major. Mol Biochem Parasitol (2004) 1.00
The KREPA3 zinc finger motifs and OB-fold domain are essential for RNA editing and survival of Trypanosoma brucei. Mol Cell Biol (2008) 0.99
Dyskinetoplastic Trypanosoma brucei contains functional editing complexes. Eukaryot Cell (2003) 0.99
Trypanosoma brucei mitochondrial respiratome: composition and organization in procyclic form. Mol Cell Proteomics (2011) 0.96
The Fe/S cluster assembly protein Isd11 is essential for tRNA thiolation in Trypanosoma brucei. J Biol Chem (2010) 0.94
Uridine insertion/deletion editing activities. Methods Enzymol (2007) 0.91
Protein composition of Trypanosoma brucei mitochondrial membranes. Proteomics (2009) 0.89
KREPB6, KREPB7, and KREPB8 are important for editing endonuclease function in Trypanosoma brucei. RNA (2011) 0.87
Editosome accessory factors KREPB9 and KREPB10 in Trypanosoma brucei. Eukaryot Cell (2012) 0.85
Paromomycin affects translation and vesicle-mediated trafficking as revealed by proteomics of paromomycin -susceptible -resistant Leishmania donovani. PLoS One (2011) 0.84
Functions and cellular localization of cysteine desulfurase and selenocysteine lyase in Trypanosoma brucei. FEBS J (2009) 0.81
Trypanosoma brucei Tb927.2.6100 is an essential protein associated with kinetoplast DNA. Eukaryot Cell (2013) 0.80
Identity crisis? The need for systematic gene IDs. Trends Parasitol (2011) 0.79
Expression of biopterin transporter (BT1) protein in Leishmania. FEMS Microbiol Lett (2002) 0.75